• 동의생리병리학회지
• /
• 제24권3호
• /
• pp.367-372
• /
• 2010

The purpose of this study is to make a basis of in vivo or clinical study about alopecia. We investigated the prescriptions of alopecia by researching oriental medicine literature. We found the prescriptions used for alopecia. And we surveyed the frequency and classification of the herbs used for alopecia. The results of this study were recorded as follows. The most frequently used single herbs in the prescriptions were Angelicae Gigantis Radix(當歸), Glycyrrhizae Radix(甘草), Poria(茯笭), Paeoniae Radix Alba(白芍藥). Herbs specifically frequently used in the prescriptions of alopecia were as follows. Polygoni Multiflori Radix(何首烏), Rehmanniae Radix(生地黃), Cuscutae Semen(菟絲子), Bupleuri Radix(柴胡), Scutellariae Radix(黃芩), Viticis Fructus(蔓荊子), Aconiti Iateralis Preparata Radix(附子). Herbs frequently used were classified by property. The result was as follows. (()-The number of herbs) 補益藥(32), 解表藥(18), 淸熱藥(15) 收澀藥(9), 活血祛瘀藥(8), 利水滲濕藥(8).

• 동의생리병리학회지
• /
• 제24권6호
• /
• pp.1129-1133
• /
• 2010

The treatment of Atopic dermatitis and its untapped herbal elements are recognized as possible solutions to incurable diseases stemming from overdosage of chemical drugs. Synthesizing clinical results from the Oriental medicine with scientific results from the field of Molecular biology is in the mainstream. The main goal of this research is, by objectifying the methodology of abstracting information into a compendium, to establish knowledge-based database on natural materials mingling every single related information from both Oriental and Western medicine. The constructed system, ATODERM, is the first database system about the medical herb for the treatment of Atopic Dermatitis which bearing the integrated information on Oriental medicine and Western medicine. The construction of this database renders new ways of treatment and prescriptions for researchers in the field of the Oriental medicine. Using the database that has been intensively accumulated, the possibility of creating the plausible cure for the disease can be anticipated.

• 대한한의학방제학회지
• /
• 제9권1호
• /
• pp.165-206
• /
• 2001

After this study, I report the following result from it 1. 'Qiao zhang' is the symptoms that the abdomen is distension and fullness, but face, eye, four limb is not dropsial swelling. It corresponds to the Gu zhang(?脹), Zhang man(脹滿), Jiju(積聚), Dan fu zhang(單腹脹), Zhong man(重滿) of the Oriental Medicine. 2. The cause and overeating and, and malfunction pathology of the 'Qiao zhang' were accumulation of water cause of overeating and, overdrinking, the hurt of feeling, overwork, infection of blood sucker and malfunction of liver, spleen and kidney for jandice and Jiji(積聚) 3. The treatment of the 'Qiao zhang' was reinforcing middle-energizer and replenishing Qi and allevating water retention because middle-energizer were much weak. 4. The prescription of the 'Qiao zhang' that Zhang man fen xiao wan(中滿分消散) were 16 times the most. Zhang man fen xiao tang(中滿分消湯), Guang man kui jian tang(廣茂潰堅湯), ren shen gui pi tang(人蔘芎歸湯), Yu yu liang wan(禹餘糧丸), mun xiang sun qi tang(木香順氣散) were next. 5. The single herb of the prescription of the 'Qiao zhang' that were Auckrandiae Radix(木香), Citri Pericarpium(陳皮) for rephenshing qi drug, Atractylodis Macrocephalae Phieoma(白朮), Ginseng Radix(人蔘), Magnoliae Cortex(厚朴) for regurating qi drug, Pinelliae Rhzoma(半夏) for dischanging phlegm drug.

• 한방안이비인후피부과학회지
• /
• 제9권1호
• /
• pp.159-165
• /
• 1996

The study was clinically performed with the 128 out patients of dermatic disease who had visited the Dept. of dermatology, Dongzhimen Hospital, Beijing traditional medical college from May 2nd to February 14th 1996. The results were as follows. 1. The dermatologic findings which showed higher incidence in this study were Acne of Melasma 27 cases($21.0\%$), Psoriasis 25($19.5\%$), Eczema including Contact dermatitis 21($16.4\%$), Seborrheic dermatitis including Alopecia of hair 12($9.3\%$) and Urticaria 11($8.5\%$). 2. The sex ratio of male to female was 4.5 : 5.5. The peak incidence of age group was 30-39($21.8\%$). 3. In the duration of disease, 37 cases($28.9\%$) were between 1 year and 5 years. 27($21.1\%$) were over 10 years. 4. About the single herb drugs, they are Angelicas gigantis Radix, Paeoniae Radix and Salviae Radix in order of frequencies. In the case of pill type, Danggui gosam hwan. Chunggan hwan. Whaeo hwan and Shinnongjiyang hwan are most frequently used. In the case of topica, Whangyeongo, Juachanggo and Soeungo are used in high frequencies. 5. For the test and surgical treatment KOH surgical treatment of Molluscum contagiosum in 8 cases and the bloody treatment of Chronic psoriasis in 3 cases.

• 한국한의학연구원논문집
• /
• 제8권1호
• /
• pp.65-74
• /
• 2002

Inflammation is a disease that continues to afflict large numbers of people and may cause other diseases, for example, rheumatoid arthritis, colon cancer, etc. prostaglandins(PGs), one of arachidonic acid metabolites, are major chemical mediators in the process of inflammation. In traditional herbal medicine, many kinds of herbal drugs have been widely used for the treatment of inflammation. So, we analyzed many publications until 2001 which worked on inhibition of $PGE_2$ synthesis by cyclooxygenase-2 (COX-2) with herbs and herb oriented single compounds. And then we tried to make interpretations of herbal traditional prescriptions for inflammation. There are significant correlations between herbal medicine prescribed and inhibitions of COX-2 activity. From our efforts and further researches, we expect to develop new-inflammatory herbal drugs which have more efficacy and fewer side effects.

• 동의신경정신과학회지
• /
• 제27권1호
• /
• pp.11-21
• /
• 2016

Objectives: This study was performed to review the research trends in the treatment of eating disorder in traditional Chinese medicine (TCM). Methods: The CNKI database (China National Knowledge Infrastructure) was searched under the key words ‘Eating Disorder’, ‘Anorexia Nervosa’, and ‘Bulimia Nervosa’. Results: Thirteen articles were selected. These included 2 studies on bulimia nervosa, and 11 studies on anorexia nervosa. According to study design, studies were classified into 1 randomized controlled trial, 2 single group before-and-after studies, and 8 case reports. According to therapy method, they included 11 herbal medicine studies, and 2 complex treatment studies. The most common pattern identification was ‘liver qi depression’ (肝氣鬱結), and the most used herb was ‘Root of Bupleurum falcatum’ (柴胡). Most of the studies showed effective results. Conclusions: The results of our study indicated that TCM clinical studies on eating disorder were being conducted more actively than in Korean medicine. Korean medical treatment might be effective to relieve eating disorder symptoms. In the future, more scientifically designed clinical studies should be performed to prove the effectiveness of traditional Korean medicine treatment on eating disorder.

• 한국의사학회지
• /
• 제31권2호
• /
• pp.73-82
• /
• 2018

Chalbyungyogyul (察病要訣) is a book of Korean Medicine which contains simple knowledges combined with experienced prescriptions. This study intends to introduce a manuscript of Chalbyungyogyul handed down in a family in Yeongwol-gun and analyze the Eui'an (醫案) in it. This book includes common sense in medicinal herbs and 142 cases of Eui'ans. The Eui'ans in Chalbyungyogyul can be divided into three types. Some Eui'ans state miraculous effects. External medical treatments are used in another group of Eui'ans. In the other Eui'ans, prescriptions composed by a single herb are applied. These characteristics are differentiated from those of preexisting Eui'ans in the history of Korean medicine which mainly include complexly prescribed internal medicines and medical discussions. This book vividly describes medical practice in the early 20th century and shows the realization of theoretical writings. Above all, it is a valuable discovery of Eui'an compilation which is rare in the history of Korean medicine.

• 대한예방한의학회지
• /
• 제23권1호
• /
• pp.49-59
• /
• 2019

Objective : We searched and collected the various ways of taking medicine in Naegyeong, Dongeuibogam and studied the possibilities to apply the traditional ways of taking medicine to the current way of taking medicine. Method : We collected all the ways of taking medicine in Naegyeong and classified the ways according to the relative importance, urgency, pathosis, time of disease, and, the conditions of patients. Result : Medicinal forms are decoction, pills, trituration, and thin porridge. Various kinds of water and the prepared rice forms were used. A single herb was boiled and its water was used to take the medicine. Also, liquor and honey were used to take medicine. More than two herbs or special prescriptions were boiled and the extract water was taken. The same medicine was taken by different boiled water according to the condition and age of a patient, time, acute or chronic illness, and, severe or mild disease. Conclusion : There are a lot of pills and trituration prescriptions in Naegyeong, Dongeuibogam. Water, various rice preparations, and several herbs are used to take these prescriptions. The reason is that these ways of taking medicine promote the medicinal effect and fast treatment to maximize the medicinal effects. From now on, the in-depth and mutilple studies are needed based on this research.

• 턱관절균형의학회지
• /
• 제13권1호
• /
• pp.1-12
• /
• 2023

Objectives: This study was performed to review the research trends in the treatment of anorexia nervosa (AN) in Traditional Chinese Medicine (TCM). Methods: Studies were searched through The China National Knowledge Infrastructure (CNKI) database. The search term for the subject were 'Eating Disorder', and 'Anorexia Nervosa'. Clinical research that conducted TCM treatment for AN patients were included. Studies were analyze according to study design, therapy method, diagnostic criteria, population and intervention. Results: 23 articles were selected. According to study design, studies were classified into two randomized controlled trial (RCT), three single group before-and-after studies, and 18 case reports. According to therapy method, they included 19 herbal medicine studies, two acupuncture treatment studies, and two complex treatment studies. The most common pattern identification was 'liver depression with spleen deficiency' (肝鬱脾虛), and the most used herb was 'Root of Bupleurum falcatum' (柴胡). Most of the studies showed effective results in increasing appetite and weight. Conclusions: The results of our study demonstrate that TCM treatments for AN has been effective in alleviating chief symptoms. However, in terms of evidence-based medicine, lack of RCT on TCM treatments for AN and absence of objective diagnostic criteria in case reports are limitations. Therefore well-designed further clinical studies should be performed based on the results of this study are recommended.

• Toxicological Research
• /
• 제29권2호
• /
• pp.91-98
• /
• 2013

Armeniacae semen (AS) has been considered a toxic herb in the Korean medicine as it contains hydrogen cyanide and amygdalin, especially in its endocarp. Therefore, prebrewed AS that is devoid of endocarp has been traditionally used. In the present study, amygdalin content of the prebrewed AS was significantly lower ($2.73{\pm}0.32{\mu}g/ml$; p<0.01) than the content in the extract that contained the endocarps ($28.50{\pm}6.71{\mu}g/ml$); amygdalin content corresponded to 10% of the extract in the present study. Because of single oral dose toxicity of prebrewed AS according to the recommendation of Korea Food and Drug Administration Guidelines (2009-116, 2009), which was based on single oral dose toxicity study of prebrewed AS, mortality due to toxic principles was significantly reduced. In this study, 2,000 mg/kg of prebrewed AS led to death of 1 female rat and 1 male rat at the end of 2 hr of administration. Based on these results, the 50% lethal dose in both male and female rats was determined to be 9279.5 mg/kg. Seizure, loss of locomotion, and increases in respiration and heart rate were observed as prebrewed AS treatment-related toxicological signs; these signs were restrictedly manifested in the prebrewed AS (2,000 mg/kg)-treated rats. In addition, no changes were observed in body weight, organ weight, gross features, and histopathological parameters with 2,000 mg/kg of AS in both male and female rats. These findings serve as direct evidence that amygdalin in AS is the toxic principle, which can be reduced by the traditional prebrewing method involving the exclusion of endocarp.