• The Korean Journal of Physiology and Pharmacology
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• 제3권6호
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• pp.547-554
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• 1999

The aim of the present study is to investigate the contribution of $Ca^{2+} ?activated\;K^+\;(K_{Ca})$ channels and delayed rectifier $K^+\;(K_V)$ channels to the resting membrane potential (RMP) in rabbit middle cerebral arterial smooth muscle cells. The RMP and membrane currents were recorded using the whole-cell patch configuration and single $K_{Ca}$ channel was recorded using the outside-out patch configuration. Using the pipette solution containing 0.05 mM EGTA, the RMP was $-25.76{\pm}5.08$ mV (n=12) and showed spontaneous transient hyperpolarizations (STHPs). The membrane currents showed time- and voltage-dependent outward currents with spontaneous transient outward currents (STOCs). When we recorded the membrane potential using the pipette solution containing 10 mM EGTA, the RMP was depolarized and did not show STHPs. The membrane currents showed no STOCs but only showed slowly inactivating outward currents. External TEA (1 mM) reversibly inhibited the STHPs, depolarized the RMP, reduced the membrane currents, abolished STOCs, and decreased the open probability of single $K_{Ca}$ channel. When $K_V$ currents were isolated, the application of 4-AP (5 mM) depolarized the RMP. The important aspect of our results is that $K_{Ca}$ channel is responsible for the generation of the STHPs in the membrane potential and plays an important role in the regulation of the RMP and $K_V$ channel is also responsible for the regulation of the RMP in rabbit middle cerebral arterial smooth muscle cells.

• The Korean Journal of Physiology and Pharmacology
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• 제7권1호
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• pp.25-28
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• 2003

Ion channel inhibitors are widely used for pharmacological discrimination between the different channel types as well as for determination of their functional role. In the present study, we tested the hypothesis that 4-aminopyridine (4-AP) could affect the large conductance $Ca^{2+}$-activated $K^+$ channel ($BK_{Ca}$) currents using perforated-patch or cell-attached configuration of patch-clamp technique in the rabbit pulmonary arterial smooth muscle. Application of 4-AP reversibly inhibited the spontaneous transient outward currents (STOCs). The reversal potential and the sensitivity to charybdotoxin indicated that the STOCs were due to the activation of $BK_{Ca}$. The $BK_{Ca}$ currents were recorded in single channel resolution under the cell-attached mode of patch-clamp technique for minimal perturbation of intracellular environment. Application of 4-AP also inhibited the single $BK_{Ca}$ currents reversibly and dose-dependently. The membrane potential of rabbit pulmonary arterial smooth muscle cells showed spontaneous transient hyperpolarizations (STHPs), presumably due to the STOC activities, which was also inhibited by 4-AP. These results suggest that 4-AP can inhibit $BK_{Ca}$ currentsin the intact rabbit vascular smooth muscle. The use of 4-AP as a selective voltage-dependent $K^+$ (KV) channel blocker in vascular smooth muscle, therefore, must be reevaluated.

• 전기전자학회논문지
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• 제21권3호
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• pp.284-287
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• 2017

본 연구에서는 3차원 소자 시뮬레이션을 통하여 단일 게이트 피드백 전계효과 트랜지스터의 전기적 특성과 채널 길이에 따른 메모리 윈도우 특성 변화를 확인하였다. 소자의 채널 길이는 50 nm에서 100 nm까지 변화시켜가며 시뮬레이션을 수행하였다. 시뮬레이션 결과 0에 가까운 문턱전압이하 기울기(< 1 mV/dec)와 ${\sim}1.27{\times}10^{10}$의 $I_{on}/I_{off}$ 비율을 얻었다. 또한 메모리 윈도우를 확인한 결과 채널 길이 50 nm의 소자는 0.31 V의 메모리 윈도우가 생성되었으나 채널 길이 100 nm의 소자는 메모리 윈도우가 생성되지 않았다.

• Journal of Advanced Marine Engineering and Technology
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• 제28권6호
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• pp.1026-1036
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• 2004

In this study, single-phase heat transfer experiments were conducted with Oblong Shell and Plate heat exchanger using water. An experimental water loop has been developed to measure the single-phase heat transfer coefficient and pressure drop in a vertical Oblong Shell and Plate heat exchanger. Downflow of hot water in one channel receives heat from the cold water upflow of water in the other channel. Similar to the case of a plate heat exchanger, even at a very low Reynolds number, the flow in the Oblong Shell and Plate heat exchanger remains turbulent. The present data show that the heat transfer coefficient and pressure drop increase with the Reynolds number. Based on the present data, empirical correlations of the heat transfer coefficient and pressure drop in terms of Nusselt number and friction factor were proposed. Also, performance prediction analyses for Oblong Shell and Plate heat exchanger were executed and compared with experiments. $\varepsilon$-NTU method was used in this prediction program. Independent variables are flow rates and inlet temperatures. Compared with experimental data, the accuracy of the program is within the error bounds of $\pm$5% in the heat transfer rate.

• 물과 미래
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• 제20권3호
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• pp.229-235
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• 1987

The purpose of this study is to estimate the parameters of linear reservoir models in order to derive the Instantaneous unit hydrograph from a given small experimental watershed. The linear reservoir model is a conceptual model, consisting of cascade or parallel equal linear reservoirs, preceded by a linear channel which involved Nash, SLR(single linear reservoir) and 2-PLR(two-parallel linear Reservoir) model. the Nash model have two parameters N and K, single linear reseroir has one parameter $K_I$ and two-parallel linear reservoirs have two parameters $K_1,\;K_2$; where N denote the number of reservoirs and K is the storage coefficient of each reservoirs.

• Journal of Communications and Networks
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• 제16권2호
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• pp.217-226
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• 2014

In this research, we study the problem of opportunistic spectrum access (OSA) in a time-varying environment with fading channels, where the channel state is characterized by both channel quality and the occupancy of primary users (PUs). First, a finite-state Markov channel model is introduced to represent a fading channel. Second, by probing channel quality and exploring the activities of PUs jointly, a two-dimensional partially observable Markov decision process framework is proposed for OSA. In addition, a greedy strategy is designed, where a secondary user selects a channel that has the best-expected data transmission rate to maximize the instantaneous reward in the current slot. Compared with the optimal strategy that considers future reward, the greedy strategy brings low complexity and relatively ideal performance. Meanwhile, the spectrum sensing error that causes the collision between a PU and a secondary user (SU) is also discussed. Furthermore, we analyze the multiuser situation in which the proposed single-user strategy is adopted by every SU compared with the previous one. By observing the simulation results, the proposed strategy attains a larger throughput than the previous works under various parameter configurations.

• 정보학연구
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• 제2권2호
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• pp.1-12
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• 1999

유통경로의 성과를 측정할 수 있는 요인들을 분류하는 접근방법은 연구자의 관점에 따라 다양하게 이루어져 왔다. 그러나 이같이 다양한 성과측정변수들이 실제로 국내의 경로 구성원에 의해 유통성과를 평가할 때 사용되고 있는지의 여부와 국내 유통경로의 경영자들이 판단하는 총체적인 경영성과에 이들 변수들이 차지하는 비중이 차별화 되고 있는지에 대한 연구는 미미하여 왔다. 이에 본 연구는 국내의 전자 유통대리점들을 대상으로 경로 구성원들이 사용하는 성과평가척도의 요소를 살펴보고 이들 요소들이 총 유통성과에서 차지하는 비중을 도출하며 경로구성원의 특성에 따른 측정요소의 차이점이 발생하는가를 검증하는데 그 목적을 두었다. 이를 위해 요인분석을 통해 성과 측정 요소들이 어떠한 공통의 집단으로 나뉘어 지는가를 살펴보며 상관분석을 통해 이들이 총 유통성과를 평가하는데 기여하는 비중을 도출한다. 이에 따른 연구의 결과를 살펴보면 경로구성원의 성과 요인은 재무적 성과 마케팅 지원 성과, 판매원 서비스 및 소비자 만족도 성과 그리고 소비자 소비스 성과의 4 요인으로 분류 되었고 재무적 성과와 마케팅 지원성과 요인이 총유통성과와의 상관도가 가장 높았다. 또한 경로구성원의 특성에 따라 성과척도의 중요 요인에 차이가 발생한다는 사실을 확인 할 수 있었다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회B
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• pp.1870-1875
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• 2007

The microchannel heat sink is promising heat dissipation method for high heat flux source. Contrary to conventional circular channel, MEMS based microchannel had rectangular or trapezoidal cross-sectional shape. In our study, we conducted three dimensional conjugate heat transfer calculation for rectangular shape microchannel. First, we simulated that channel was completely drained with known heating power. As a result we obtained calibration line, which indicates heat loss was function of temperature. Second, we simulated single phase heat transfer with various mass flux, 100-400 $kg/m^2s$. In conclusion, the single phase test verified that the present heat loss evaluation method is applicable to micro scale heat transfer devices. Heat fluxes from each side wall shows difference due to non-uniform heating. However those ratios were correlated with supplied total heat. Finally, we proposed effective area correction factor to evaluate appropriate heat flux.

• International Journal of Fluid Machinery and Systems
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• 제2권3호
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• pp.239-247
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• 2009

Sewage pumps are designed with a wide flow channel by, for example, sacrificing some efficiency and reducing the number of blades, in order to prevent plugging with foreign bodies. However, the behavior of foreign bodies which actually flow into a pump is extremely complex, and there are questions about whether the presumed foreign bodies will actually pass through. This paper proposes a new type of sewage pump impeller designed to further improve pump efficiency and performance in passing foreign bodies. This sewage pump impeller has a structure in which the suction flow channel of a closed type non-clog pump is wound in a helical spiral. The focus of this research was to investigate pump performance and internal flow in this single blade sewage pump impeller. The results clearly indicated the following facts: The developed sewage pump impeller exhibits high efficiency over a wide range of flow rates; internal flow of the pump is very complicated; and the internal flow state varies greatly when the flow rate changes.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2003년도 추계종합학술대회
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• pp.737-740
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• 2003

대부분의 디지털 방송 시스템에서는 한정된 지상파 주파수 자원 때문에 최소한의 주파수 자원을 사용하는 SFN 또는 OCR등의 기법을 제공하고 있다. 본 논문에서는 미국 ATSC방식의 OCR과 유럽의 DVB-T방식의 SFN에 대한 특성을 연구 분석하고 중계기 및 송신기의 위치에 따른 수신영역을 시뮬레이션 하기 위한 방안을 제시한다.