• 재활치료과학
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• 제4권2호
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• pp.73-83
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• 2015

목적 : 본 연구는 오차배제훈련을 병행한 시간차회상훈련이 경도인지장애(Mild Cognitive Impairment; MCI) 환자의 기억력에 미치는 효과와 수단적 일상생활(Instrumental Activities of Daily Living; IADL) 및 우울에 미치는 영향을 알아보고자 하였다. 연구방법 : 주간보호시설에 등록된 78세 MCI 노인을 대상으로 단일 대상 실험 연구 중 ABA 설계를 사용하여 실험을 진행하였다. 연구를 진행한 총 16회기 중 기초선 A는 총 3회기, 중재기간 B는 총 10회기, 기초선 A'는 총 3회기였다. 기억력을 측정하기 위한 회기별 평가로 Rey-Kim 언어 기억 검사(K-Auditory Verbal Learning Test; K-AVLT)를 사용하였고, 인지기능, IADL 수행 능력, 우울을 측정하기 위하여 각각 한국판 몬트리올 인지평가(Korean version of Montreal Cognitive Assessment; MoCA-K), 필라델피아 노인 센터 IADL 도구(Philadelphia Geriatric Center Instrumental Activities Daily Living; PGC IADL), 한국판 노인우울척도(Geriatric Depression Scale Korean Version; GDS-K)를 사용하였다. 결과 : 대상자는 기초선 A기간에 비하여 중재를 제공한 B기간에서의 즉시회상 및 지연회상이 현저히 증가하였다. 또한, 즉시회상과 지연회상 모두 B 기간에서 증가하던 측정값의 경향이 중재를 제거한 후인 기초선 A'구간에서 감소하는 경향을 보였다. MoCA-K 점수는 향상을 보였으며, PGC IADL 점수는 중재 전과 후가 같았고 GDS-K의 점수는 감소하였다. 결론 : 본 연구의 결과를 통하여 MCI 환자를 대상으로 실시한 오차배제훈련을 병행한 시간차 회상훈련의 근거를 확고히 하였다. 나아가 MCI 환자들이 기억력과 함께 어려움을 겪는 요인을 향상시키기 위한 중재 및 기억력과 다른 기능적 요소들에 대한 상관관계에 대하여 추가적인 연구가 필요할 것이다.

• 대한지역사회작업치료학회지
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• 제5권2호
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• pp.31-42
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• 2015

목적 : 상상연습(mental practice)이 노인의 균형 능력에 미치는 효과를 규명하고 노인 낙상 예방을 위한 효과적인 중재 방법으로써 적용 가능성에 대해 알아보는 것이었다. 연구방법 : 본 연구는 2013년 7월부터 10월 까지 인지에 문제가 없고 낙상에 경험이 있지만 보조 도구 없이 자립보행이 가능한 65세 이상 노인 3명에게 상상연습을 제공하였다. 개별 사례 실험 연구 중 ABA' 설계를 사용하여 기초선 과정 4회기, 중재 과정 5회기, 재 기초선 과정 4회, 총 13회기로 진행되었다. 독립변수는 노인의 균형 능력 및 낙상 효능감 증진을 위해 상상연습을 사용하였고, 종속변수로는 전반적 균형능력의 변화를 알아보기 위해 버그 균형 척도(Berg Blance Scale; BBS), 낙상효능감에 변화를 알아보기 위해 낙상효능감척도(Fall Efficacy Scale: FES), 정적, 동적 균형에 변화를 측정하기 위해 각각 외다리기립검사(One-Leg Standing test; OLS), 일어나 걸어가기 검사(Timed Up & Go test : TUG)를 실시하였다. 결과 분석은 평균값과 시각적 그래프를 통해 제시하였다. 결과 : 상상연습 기법 적용 후 모든 대상자의 낙상효능감이 기초선 과정에서 측정된 수치 보다 증가된 결과를 보였으며 또한 전반적 균형 능력과 정적 동적 균형 능력 또한 증진 또는 유지 되었다. 결론 : 본 연구는 상상연습이 노인의 낙상효능감과 균형능력의 향상과 유지에 효과가 있는 것으로 나타났음으로 노인의 낙상 예방 활동으로 상상연습의 적용을 추천한다.

• 한국전문물리치료학회지
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• 제8권1호
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• pp.76-88
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• 2001

Back extension exercises have been used for rehabilitation of the injured low back, prevention of injury, and fitness training programs. However, excessive loading on low back can exacerbate existing structural weakness. The purpose of this study was to compare muscle activity of low back muscles during back extension exercises. Twenty healthy male subject s were evaluated. Electromyographic (EMG) activities of low back muscles at L1 and L5 level were recorded during seven different back extension exercises and two reference tasks by surface EMG and saved for data analysis. Reference tasks of lifting 20% and 40% of their body weight were included for comparison. The result were as follows: 1) Single-arm extension and single-leg extension exercises on quadruped position appeared to constitute a low-risk exercise for initial extensor strengthening. 2) When arm extension was combined with contralateral leg extension on quadruped position, EMG activities of low back muscles were increased. 3) EMG activity of low back muscles was highest during the trunk extension exercises on prone position. 4) EMG activities of low back muscles during arm and leg extension exercises on quadruped position were less than those of reference task of lifting 40% of their body weight. These result s have important implications for progressive back extensor muscle strengthening exercises in patients with back pain.

• 대한약침학회지
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• 제15권3호
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• pp.48-52
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• 2012

Objective: This study was performed to analyze the single-dose toxicity of Aconitum kusnezoffii Reichb. pharmacopuncture (AKRP). Methods: All experiments were conducted at the Korea Testing & Research Institute (KTRI), an institute authorized to perform non-clinical studies, under the regulations of Good Laboratory Practice (GLP). Twenty (20) Sprague-Dawley rats were chosen for the pilot study. The animals were divided into four groups of five animals per group: group 1 (G1) being the control group with each animal receiving an injection of 0.3 ml of saline and groups 2, 3, and 4 (G2, G3, and G4) being the experimental groups with each animal receiving an injection of 0.1, 0.2 or 0.3 ml of AKRP, respectively. This study was conducted with the approval of the Institutional Animal Ethics Committee. Results: No deaths occurred in any of the 4 groups, and the $LD_{50}$ of AKRP administered via IV was higher than 1.77 ml/kg. Some changes in the weights of the male rates were observed between the control group and the experimental groups, but no significant differences were noted in the weights of the female rats. To check for abnormalities in organs and tissues, we stained representative sections of each specified organ with Hematoxylin & Eosin for light microscopic examination. The results showed no significant differences in any of the organs or tissues. Conclusions: The above findings suggest that Aconitum kusnezoffii Reichb. pharmacopuncture is a relatively safe treatment. Further studies on the subject should be conducted to yield more concrete evidence.

• 과학교육연구지
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• 제40권1호
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• pp.17-30
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• 2016

이 연구의 목적은 STEAM 프로그램의 문제해결활동이 중학생들의 메타인지에 어떤 영향을 미치는지 알아보기 위한 것이다. 연구 대상은 63명의 중학생이다. 이 연구는 단일집단 사전사후 검사로 설계되었다. 중학생들의 메타인지에 관한 사전 사후 검사간 유의미한 차이가 있는지 알아보기 위해 단일집단 t-test를 실시하였다. 분석 결과 중학생들의 메타인지는 사전 사후 검사간 유의미한 차이가 있는 것으로 나타났다. 또한 메타인지적 지식과 메타인지적 조절에 대한 t-test 결과에서도 사전 사후 검사간 유의미한 차이가 있는 것으로 나타났다. 메타인지적 지식의 하위 요소에 대한 분석에서도 사전 사후간 유의미한 차이를 보였다. 이 연구에서는 메타인지 하위 요소들간 관계를 알아보기 위해 다중회귀분석을 실시하였다. 분석 결과 메타인지 하위 요소들은 높은 설명력을 나타내었다. 이와 같은 결과는 STEAM 프로그램의 문제해결활동이 학습자의 메타인지 촉진에 긍정적 영향을 미칠 수 있음을 시사하고 있다.

• 대한예방한의학회지
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• 제10권1호
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• pp.95-107
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• 2006

This study was explore the level of Yangseng by certain elderly people in Dalian, china. The subject of this study is(randomly) selected Dalian residents over 65 years-old. We used a formultaed questionnaire for this research during the period from October 2004 to November. 266 subjects in total answered to the questionnaire. The analyses are as follows: 1. Man does more Exercise Yangseng than woman. Elderly with spouse has better Total of Yangseng, Exercise Yangseng, Seasonal Yangseng, Sex life Yangseng than single elderly. Compare to elderly living with family other than their spouse, single elderly has better Total of Yangseng, Diet Yangseng, Activities and rest Yangseng, Exercise Yangseng, Sex life yangseng. 2. Educated elderly has better life than illiterate in every aspects except Diet Yangseng and Seasonal Yangseng. Elderly who does not belive in any religion has better Activities and rest Yangseng and Seasonal Yangseng. Religious elderly has better sleep yangseng than irreligioius elderly. Elderly with occupation has better Total of Yangseng, Activities and rest Yangseng, Exercise Yangseng and Sex life Yangseng. 3. Elderly who support himself of the living expense has better Sleep Yangseng, and elderly who support himself with his sons and daughters has better Morality Yangseng, Exercise Yangseng, Seasonal Yangseng and Sex life Yangseng. Elderly who has time to spare has better life than elderly who has bo leisure in Total of Yangseng and other 8 sub-factors.

• 대한약침학회지
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• 제18권3호
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• pp.63-67
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• 2015

Objectives: This study was performed to analyze the single-dose oral toxicity of the super key (processed sulfur). Methods: All experiments were conducted at Medvill, an institution authorized to perform non-clinical studies, under the Good Laboratory Practice (GLP) regulations. In order to investigate the oral toxicity of super key. We administered it orally to Sprague-Dawley (SD) rats. The SD rats were divided into four groups of five male and five female animals per group: group 1 being the control group and groups 2, 3, and 4 being the experimental groups. Doses of super key 500 mg/kg, 1,000 mg/kg and 2,000 mg/kg were administered to the experimental groups, and a dose of normal saline solution, 10 mL/kg, was administered to the control group. We examined the survival rates, weights, clinical signs, gross findings and necropsy findings. This study was conducted under the approval of the Institutional Animal Ethics Committee. (Approval number: A01-14018). Results: No deaths or abnormalities occurred in any of the four groups. Although slight decreases in the weights of some female rats were noted, no significant changes in weights or differences in the gross findings between the control group and the experimental groups were observed. To check for abnormalities in organs, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs. Conclusion: The results of this research showed that administration of 500 - 2,000 mg/kg of super key did not cause any changes in the weights or in the results of necropsy examinations. Neither did it result in any mortalities. The above findings suggest that treatment with super key is relatively safe. Further studies on this subject are needed to yield more concrete evidence.

• 한국가족관계학회지
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• 제22권3호
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• pp.47-72
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• 2017

Objectives: Do husbands with working wives share domestic labor more equally than husbands with unemployed housewives? Is the husband's contribution sufficient enough to satisfy his wife? These questions have long inspired many researchers to find ways to more accurately estimate husband's domestic contributions and narrow the emotional gap following the different threshold of satisfaction within couples, but not without some limits. This study attempted to figure out an answer to the above-mentioned subject by using time diaries of Korean married couples with a preschooler as their first-born child and relying on the typology of husbands' sharing of housework and childcare, which allowed me to overcome some limitations of prior research. Method: I analyzed a total of 1,716 diaries of 858 married couples from 2014 Korea Time Use Survey with descriptive statistics, t-test, cluster analysis, and multinomial logit. Results: Analytic results showed that husbands in dual-earner households did share domestic labor more equally than husbands in single-earner households, but there were different types of husband's contribution depending on time they spent in housework and childcare. While more than half of husbands with employed wives shared more or less than ten percent of domestic labor, the rest were divided into one group of husbands who shared both housework and childcare more heavily and evenly, and another group who were mainly involved in childcare duties. It is interesting that husbands who made the least contributions to domestic labor were not the ones with the lowest level of satisfaction with their sharing of household labor, whereas their wives were deeply dissatisfied, leading to a huge emotional gap within couples. Conclusion: Identifying factors associated with the three different types allowed me to find a point of intervention to narrow the emotional gap that is likely to harm the marital relationship if left unattended to.

• Nutrition Research and Practice
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• 제17권1호
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• pp.62-72
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• 2023

BACKGROUND/OBJECTIVES: Many studies have revealed an association between fat mass and the obesity-related gene (FTO) and obesity. On the other hand, no meta-analysis was conducted with data from only Koreans. Therefore, this study performed a meta-analysis using Korean data to provide evidence for the association between FTO single nucleotide polymorphisms (SNPs) and the risk of obesity among Korean adults. SUBJECT/METHODS: Meta-analysis was finally conducted with data extracted from seven datasets of four studies performed on Korean adults after the screening passed. Five kinds of FTO SNPs (rs9939609, rs7193144, rs9940128, rs8050136, and rs9926289) were included, and the relationship between FTO SNPs and body mass index (BMI) was investigated using linear regression with an additive model adjusted for covariants, such as age, sex, and area. RESULTS: The minor alleles of FTO SNPs were associated with increased BMI (odds ratio [OR], 1.31; 95% confidence interval [CI], 1.21-1.42). In sub-group analysis, FTO rs9939609 T>A was significantly associated with BMI (OR, 1.23; 95% CI, 1.06-1.42). The other FTO SNPs together were significantly associated with BMI (OR, 1.37; 95% CI, 1.25-1.49). The publication bias was not observed based on Egger's test. CONCLUSIONS: This meta-analysis showed that minor alleles in the FTO SNPs were significantly associated with an increased BMI among Korean adults. This meta-analysis is the first to demonstrate that minor alleles in the FTO SNPs contribute significantly to the increased risk of obesity among Korean adults using data from a Korean population.

• 방사성폐기물학회지
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• 제9권1호
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• pp.1-11
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• 2011

에멀션 기반의 계면활성제를 이용한 주형합성법을 이용하여 산촉매로서 염산과 실리카의 전구체인 테트라에톡시실란을 사용함으로써 메조다공성 실리카 마이크로스피어를 합성하였다. 테트라에톡시실란의 농도 증가에 의해 구형의 입자 형태가 파괴되었고, 기공구조도 크게 변하였다. 산촉매 농도 증가에 의한 구형의 입자형태 파괴 현상은 적었지만 상대적으로 작은 크기의 구형의 마이크로입자가 더 많이 생성되었다. 하지만, 산성조건에서 입자들 간의 강한 응집현상이 나타남에 따라 낱개의 분리되어 있는 단일입자를 얻기 위해서는 초음파 등의 후처리 과정이 필요하였다.