• 제목/요약/키워드: Single Subject Experimental Study

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Obligatory Control and Coordinated Deletion as Korean Subject Diagnostics: An Experimental Approach

  • Kim, Ji-Hye;Lee, Yong-hun;Kim, Eunah
    • 한국언어정보학회지:언어와정보
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    • 제19권1호
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    • pp.75-101
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    • 2015
  • This study investigated the distribution of subject properties in Korean. Based on the previous studies on so-called 'subjecthood diagnostics' in Korean Multiple Subject Constructions (MSCs), the current study investigates how different subject properties are distributed in single subject constructions (Non-MSCs) and MSCs. Focusing on two distinct subject properties - obligatory control (OC) of PRO and coordinated deletion (CD) - an empirical syntactic experiment was designed to test how these two subjecthood diagnostics behave in the Non-MSC and MSC environments. Seventy Korean native speakers were tested over magnitude estimation task, composed of 80 Korean sentences representing different subject properties in single or multiple subject constructions. Overall results showed (i) both OC and CD can be used as subjecthood diagnostic tests in the Non-MSC environments, but (ii) that only OC can be used as a subjecthood diagnostic test in the MSC environments.

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편측무시 환자에게 실시간 초음파 영상을 이용한 왼쪽 몸통 굽힘 패턴을 적용한 과제지향적 훈련의 효과 -단일 사례 연구- (The Effects of Task-Oriented Training for Left Trunk Flexion Pattern Using Real-Time Ultrasound Imaging -A Single-Subject Experimental Study-)

  • 김지선;기경일;강태우
    • PNF and Movement
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    • 제17권1호
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    • pp.1-9
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    • 2019
  • Purpose: This study investigates the effects of task-oriented training for a left trunk flexion pattern using real-time ultrasound imaging in a stroke patient with unilateral neglect symptoms. Methods: This study used the ABA experimental design, which is a single-subject research method among individual case research methods. For the ABA experimental design, changes in the degree of unilateral neglect, balance ability, and the thickness of the lateral abdominal muscle were visually analyzed during the baseline process, in the intervention period, and after the intervention. The experiments were performed 24 times in total for 8 times in each of the 3 periods. The unilateral neglect was measured using the Albert test, balance ability was measured using the Berg balance test, and the thickness of the lateral abdominal muscle was measured using ultrasound imaging. The subject was a 50-year-old male patient with unilateral neglect caused by right cerebral hemorrhage. He performed task-oriented training for a voluntary left trunk flexion pattern using real-time ultrasound imaging during the intervention period. Results: The result of comparing the data collected during the intervention period with the data point average of the baseline process showed that balance ability improved and the tendency line was above the baseline. The tendency line of unilateral neglect was below the baseline and showed a decreasing tendency. The thickness of the lateral abdominal muscle showed an increasing trend and the tendency line was above the baseline. Conclusion: The results of this study suggest that the task-oriented training for left trunk flexion pattern using real-time ultrasound imaging has a beneficial effect on balance ability, the degree of unilateral neglect, and the strength of the lateral abdominal muscle in unilateral neglect patients.

외반슬 환자의 교정운동의 효과: 단일 피험자 A-B-A 실험 설계 (The Effect of Corrective Exercise in a patient with knee joint valgus deformity: A single-subject A-B-A experimental design)

  • 이호성;김아람
    • 대한물리의학회지
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    • 제11권1호
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    • pp.93-105
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    • 2016
  • PURPOSE: The purpose of this study was to determine the effect of corrective exercise on hip joint range of motion, lower limb alignment, radiographs of hip and knee joints, and quadriceps muscle activity in a patient with knee joint valgus deformity. METHODS: A single-subject A-B-A experimental design was used to determine the effects of therapeutic exercise. The single-subject was a 27-year-old male, who presented with knee joint valgus deformity. Corrective exercise program was performed for 40 min/day twice a week for 12-week. Range of motion (hip flexion, extension, abduction, adduction, internal rotation, and external rotation), lower limb alignment test (Q-angle, rear foot alignment, and leg length), standing anterior-posterior radiographs (neck shaft angle and knee joint space), and quadriceps muscle activity of both lower limbs were measured before (A 1), after 6 weeks (B 1) and after 12-weeks (B 2) of corrective exercise and after 6 weeks of exercise completion (A 2). RESULTS: Hip range of motion increased in all directions of both sides at B 2 and A 2 compared to at A 1. Q-angle of both side and leg length discrepancy decreased at B 2 and A 2 compared to at A 1. Neck shaft angle and knee joint space of both sides improve at B 2 and A 2 compared to at A 1. Quadriceps of both side muscle activities improved at B 2 and A 2 compared to at A 1. CONCLUSION: We demonstrated that corrective exercise increases range of motion, and improves lower limb alignment and muscle activity in a patient with knee joint valgus deformity.

Can the Energy Costs of Speech Movements be Measured\ulcorner A Preliminary Feasibility Study

  • Bjorn Lindblom;Moon, Seung-Jae
    • The Journal of the Acoustical Society of Korea
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    • 제19권3E호
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    • pp.25-32
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    • 2000
  • The main question addressed in this research was whether an adaptation of a standard exercise Physiology Procedure would be sensitive enough to record excess oxygen uptake associated with speech activity. Oxygen consumption was recorded for a single subject during 7-minute rest periods and an automatic speech task, also 7-minutes long and performed at three different vocal efforts. The data show measurable and systematic speech-induced modifications of breathing and oxygen uptake patterns. The subject was found to use less power for normal than for soft and loud speech. This result is similar to findings reported by experimental biologists on the energetics of locomotion. However, more comprehensive feasibility studies need to be undertaken on a larger population before solid and detailed conclusions about speech energy costs are possible. However, it appears clear that, for experimental tasks like the present one, i.e., variations in vocal effort, standard exercise physiology methods may indeed offer a viable approach to recording excess oxygen uptake associated with speech movements.

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류마토이드 관절염의 연구동향에 대한 소고(小考) -2004년 이후의 국내 학위논문 및 학회지 논문을 중심으로- (An Analysis of the Study Tendency on Rheumatoid Arthritis -Focusing on Domestic Theses for a Degree and Journal Since 2004-)

  • 최용훈;윤일지
    • 한방재활의학과학회지
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    • 제19권2호
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    • pp.125-156
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    • 2009
  • Objectives : To research the trend of studies related to rheumatoid arthritis and to indicate the hereafter direction for its study in oriental medicine and its treatment. Methods : I reviewed 75 domestic oriental medical journals, and 50 medical journals about rheumatoid arthritis published after 2004, and comparative analysis was made. And these theses were classified by college, year, field of study, subject. Results : The following are the results of this study. 1. Classified by oriental medical college, Dae-jeon college published the most theses, followed by Dong-guk, Kyung-hee, Se-myung and Dong-shin college. Han-yang college published the most theses among college of medicine. 2. Classified by type of thesis, experimental theses(70 pieces, 94%) showed higher rate than that of clinical theses(4 pieces, 5%) in oriental medical studies. However, in medical studies, clinical theses(34 pieces, 68%) showed higher rate than that of experimental theses(15 pieces, 30%). 3. Analyzed by subject, the most dealt subject in oriental medicine was herb medication, followed by herbal acupuncture, single herb, electroacupuncture, sasang & gene, acupuncture & moxibustion, complex accordingly. The most dealt subject in medical clinical journals was standards of diagnosis & prognosis, followed by medication, gene analysis, pathogenesis, clinical pattern, operative treatment and complication accordingly. 4. In theses related to herb medication, most of the subject was to evaluate anti-inflammatory and immunoregulatory effects of herb medication with geopungseup, jibitong, hwalhyeolgeoer function. The tendency of experimental methods was focusing on understanding anti-inflammatory and immunoregulatory mechanisms through molecular biologic methods by analyzing cytokine and gene. 5. Most of theses related to herbal acupuncture were experimental studies verifying ant-inflammatory and immnoregulatory effects through methods observing change of cytokine and immunoregulatory factors. Regarding remedies for herbal acupuncture, Ulmus davidiana Planch was most preferred, followed by bee venom. 6. In theses related to single herb, Boik-yak was most prefered, followed by Geopungseup-yak and Hwalhyeolgeoer-yak. Regarding methods of research, there were tendency of shifting from methods verifying travail, anti-inflammatory and anti-pyretic effects through a test of behavior, morphometry, serology and temperature measurement of the rectum and the skin into verifying anti-inflammatory and immunoregulatory effects through observing inflammatory cytokine in the joint and cells of spleen. 7. In theses related to electroacupuncture, ST36 and adjuvant were most preferred as acupoints and induced factor. The tendency of experimental methods was turning from verifying mechanism of travail effect to analyzing inflammation and pain inducing factors. 8. Diverse medical clinical studies were published. Subjects such as diagnosis and prognosis, medication, gene analysis, clinical pattern, operational treatment, complication and pathogenesis were published. Especially, studies about standards of early diagnosis, and research on possible parallel medications with methotrexate were actively inquired. 9. Most of theses related to medical experimental studies was about mediators and receptors related to inflammatory induction and osteoclasia mechanism. Also, it was presented blockage of them can be effective on rheumatoid arthritis. Conclusions : The oriental medicine studies have merit in its diversity of treatment, but it clinical studies is lacking compared to experimental studies. Also, more diversity of subjects is necessary. Therefore, complementary measures are needed. Hereafter, oriental medicine research about rheumatoid arthritis needs more clinical research verifying the effectiveness and safety in clinical field. Also, we require oriental medical standard of diagnosis and researches on pathological generation which would make early checkup and prognosis possible.

말 태반 가수분해 추출물의 Sprague-Dawley Rat를 이용한 단회 경구투여 독성시험 (Study on a Single Oral Dose Toxicity Test of Horse Placenta Hydrolysate Extract in Sprague-Dawley Rats)

  • 여인호;김이화;이은용
    • Journal of Acupuncture Research
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    • 제31권1호
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    • pp.105-110
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    • 2014
  • Objectives : The objective of this study is to analyze the single-dose toxicity of horse placenta hydrolysate extracts. Methods : Sprague-Dawley rats were chosen for the study. Doses of horse placenta hydrolysate extracts, 2,000 mg/kg, 1,000 mg/kg and 500 mg/kg, were administered to the experimental group, and the same doses of normal saline solution were administered to the control group. This study was conducted under the approval of the Institutional Animal Ethics Committee. Results : In all 4 groups, no deaths occurred, and the horse placenta hydrolysate extracts administered by oral was over 2,000 mg/kg. No significant changes in the weight between the control group and the experimental group were observed. To check for abnormalities in organs and tissues, we used microscopy to examine representative histological sections of each specified organ, the results showed no significant differences in any organs or tissues. Conclusions : The above findings suggest that treatment with horse placenta hydrolysate extracts is relatively safe. Further studies on this subject should be conducted to yield more concrete evidence.

전신 진동 운동이 만성 뇌졸중 환자의 슬관절신전근력, 균형 및 보행능력에 미치는 영향 (The Effects of Whole Body Vibration on Knee Extensor Strength, and Balance and Walking Ability with Chronic Stroke)

  • 인태성;송창호
    • 대한물리의학회지
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    • 제5권4호
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    • pp.675-683
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    • 2010
  • Purpose : The purpose of this study was to evaluate the effect of Whole body vibration exercise(WBVE) in patient with chronic stroke. Methods : Thirty patients were divided into two groups by randomly experimental group(14 subject) and control group(16 subject) in a single blinded, randomised study. experimental group was conducted for the 6-weeks WBVE program and had a structured exercise program for 16 minutes, 5 days per week and control group was conducted for the shame exercise program. Outcome variables included the knee extensor strength, Berg balance scale, Timed up and go test at 0 and 6 weeks. Results : The experimental group tended to improve more than the control group in balance(Berg balance scale) and walking ability(Timed up and go test). There were no trends in differences in change scores by the knee extensor strength. Conclusion : WBVE program may be helpful to improve knee extensor strengthening, dynamic balance and walking ability for patients with chronic patients.

CPAP 치료 프로그램이 이완형 마비성구어장애자의 과대비성 개선에 미치는 효과 (The Effects of CPAP Therapy on Hypernasality in a Flaccid Dysarthric Patient: A Case Study)

  • 황영진;김하경;정옥란;예미경
    • 음성과학
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    • 제12권2호
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    • pp.129-138
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    • 2005
  • This study aimed at investigating the effects of CPAP therapy on hypernasality in flaccid dysarthria. The subject was a flaccid dysarthric patient with hypernasality. An A-B-A experimental research design was used. The therapy program was conducted 16 sessions. During CPAP therapy, the subjects was required to repeat single-word utterances in the form VNCV. The results showed some improvement in decreasing hypernasality.

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Mitochondrial Myopathy 환자에서 과제지향적 상지운동과 탄성밴드를 이용한 기능적 근력증진 프로그램이 상지근력과 일상생활활동에 미치는 영향 -단일사례연구- (The Effect of Task-oriented Arm Movements and Muscle Enhancement Program Using Elastic Bands on Upper Limb Muscle Strength and Activities of Daily Living of Mitochondrial Myopathy Patient -Single subject design-)

  • 박형기;이강성
    • PNF and Movement
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    • 제8권1호
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    • pp.11-19
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    • 2010
  • Purpose : The purpose of this study was to the effect of task-oriented arm movements and muscle enhancement program using elastic bands on limb muscle strength and activities of daily living of mitochondrial myopathy patient. Method : Single-subject experimental research design was applied to. AB Design was adopted. The study period was approximately four weeks. A baseline period of the three sessions of the experiment, the treatment period B, 3 sessions were conducted. Baseline period to observe the patient's daily life bardel index was measured as an independent feature, MMT as a limb muscle strength was assessed by measuring early. During the period of treatment with serabaendeu limb strength training 30 minutes after the break five minutes after the treatment using MMT limb muscle strength were evaluated. Task-oriented exercise program, and who exercise a week as a treatment was carried out in 30 minutes. Result : All of the scores for each sessional period of treatment when compared to base line and upper limb muscle strengthening exercises on the subjects that did not change significantly. Conclusion : If the muscles and nervous system involvement in patients with symptoms such as muscle weakness and paralysis of upper extremity functional use is difficult.

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Effects of Vojta Therapy on the Forced Vital Capacity and Forced Expiratory Volume at One Second in Young Male Smokers: A Single-Subject Design

  • Kim, Jin Seon;Kim, Da Young;Kim, Hee Sun;Park, Si Won;Lee, Yun Jeong;Lim, Hyoung Won
    • The Journal of Korean Physical Therapy
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    • 제31권5호
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    • pp.261-265
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    • 2019
  • Purpose: This study examined the effects of Vojta therapy on the respiratory function in young male smokers. Methods: Three subjects were tested using the ABA design for Single-subject Experimental Research Design. This study was conducted with the baseline, intervention, and follow-up phase. Intervention was conducted three to four times a week for 20 minutes per times and a total of 25 sessions. The respiratory function was measured using a Spirometer. Results: The results of Forced Vital Capacity and Forced Expiratory Volume at one second for all subjects showed improvements in the intervention phase over the baseline phase. In the follow-up phase, the improved ability was still maintained or slightly reduced. Conclusion: Vojta therapy used on young male smokers was effective in both FVC and FEV1. In other words, the Vojta therapy worked effectively in improving the respiratory function. In future studies, it is necessary to have a control group and increase the number of trials in order to generalize the effect of Vojta therapy.