• 한국추진공학회지
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• 제24권4호
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• pp.1-11
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• 2020

본 연구에서는 추진제 연소면적을 조절하여 이중추력 프로파일을 구현하는 단일연소관 이중추력 로켓모터의 내탄도성능 분석 방법을 제시한다. 천이 구간에서의 연소속도 보정계수 및 비추력의 점진적 변화를 고려하며 성능 예측에 필요한 변수를 획득할 수 있는 분석법을 제시하고, 해당 분석법을 적용한 결과와 천이 구간 내 변화를 고려하지 않는, 기존 연구의 분석법을 적용한 결과를 비교함으로써 새로 제시하는 분석법에서 개선된 부분을 확인한다. 추진제 초기 온도 또는 배치 조건이 다른 네 가지의 시험 조건에 대하여 제시하는 분석법을 이용해 내탄도 변수를 획득하고, 이를 이용하여 각 시험 조건별로 성능 예측을 수행한다. 해당 예측 결과는 실제 연소시험 결과와 잘 일치하며, 따라서 본 연구의 분석법을 기반으로 설계 형상이 동일한 이중추력 모터의 성능 예측이 가능함을 확인할 수 있다.

• Journal of Chest Surgery
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• 제56권1호
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• pp.6-13
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• 2023

Background: Coronavirus disease 2019 (COVID-19) has been found to cause life-threatening respiratory failure, which can progress to irreversible lung damage. Lung transplantation can be a life-saving treatment in patients with terminal lung disease (e.g., acute respiratory distress syndrome caused by infection). This study aimed to present the clinical course and results after initial lung transplantation in patients with severe COVID-19 who did not recover even with optimal medical care. Methods: From August 2019 to February 2022, this study enrolled 10 patients with COVID-19 (5 men; median age, 55.7 years) who underwent lung transplantation at a single center in Korea. All patients' characteristics, clinical pathway, overall survival, complications, and operative data were collected and analyzed. Results: Veno-venous extracorporeal membrane oxygenation or an oxygenator in a right ventricular assist device circuit was applied to 90% of the patients, and the median length of extracorporeal life support before operation was 48.5 days. There were no cases of mortality after a median follow-up of 372.8 days (interquartile range, 262.25-489 days). The major complications included the requirement for postoperative extracorporeal membrane oxygenation support in 2 cases (20%), re-transplantation in 1 case (10%), and re-exploration due to bleeding in 2 cases (20%). During the follow-up period, 3 out of 10 patients died. Conclusion: Excellent early outcomes were observed for patients who underwent lung transplantation. Thus, lung transplantation can be an effective and feasible treatment for patients with end-stage lung disease caused by COVID-19.

• Nutrition Research and Practice
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• 제17권6호
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• pp.1211-1224
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• 2023

BACKGROUND/OBJECTIVES: This study aimed to evaluate the food sources of zinc and the usual intake of dietary zinc among Korean toddlers and preschool children. SUBJECTS/METHODS: A total of 2,679 children aged 1-5 years was selected from the 2009-2013 Korea National Health and Nutrition Examination Survey (KNHANES) data. Dietary data collected from a single 24-h recall were used to evaluate the food sources of zinc. To estimate usual zinc intake, the distribution obtained from single 24-h recall data in the total sample was adjusted using the ratio of within-to-between-person variance in zinc intake obtained from 2-day 24-h recall sub-sample data of the 2009 KNHANES. The proportion of children with usual zinc intake below the estimated average requirement (EAR) and above the tolerable upper intake level (UL) was assessed. RESULTS: The main sources of zinc in Korean children were grains, dairy products, and meat. The mean usual intakes of zinc among all individuals, those aged 1-2 yrs, and those aged 3-5 yrs were 5.50, 5.01, and 5.83 mg/d, respectively. In all participants, 1.1% of the children consumed zinc below the EAR, whereas 10.7% exceeded the UL. The proportion of children with excessive zinc intake was 25.6% in the 1-2 yrs age group and 0.6% in the 3-5 yrs age group. CONCLUSIONS: According to the current UL, the risk of excessive zinc intake appears to be high among Korean toddlers. Future studies that monitor the health effects of excessive zinc intake are needed to appropriately guide zinc intake in children.

• Journal of Chest Surgery
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• 제57권1호
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• pp.36-43
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• 2024

Background: Coronavirus disease 2019 (COVID-19) can lead to acute respiratory failure, which frequently necessitates invasive mechanical ventilation and extracorporeal membrane oxygenation (ECMO). However, the limited availability of ECMO resources poses challenges to patient selection and associated decision-making. Consequently, this retrospective single-center study was undertaken to evaluate the characteristics and clinical outcomes of patients with COVID-19 receiving ECMO. Methods: Between March 2020 and July 2022, 65 patients with COVID-19 were treated with ECMO and were subsequently reviewed. Patient demographics, laboratory data, and clinical outcomes were examined, and statistical analyses were performed to identify risk factors associated with mortality. Results: Of the patients studied, 15 (23.1%) survived and were discharged from the hospital, while 50 (76.9%) died during their hospitalization. The survival group had a significantly lower median age, at 52 years (interquartile range [IQR], 47.5-61.5 years), compared to 64 years (IQR, 60.0-68.0 years) among mortality group (p=0.016). However, no significant differences were observed in other underlying conditions or in factors related to intervention timing. Multivariable analysis revealed that the requirement of a change in ECMO mode (odds ratio [OR], 366.77; 95% confidence interval [CI], 1.92-69911.92; p=0.0275) and the initiation of continuous renal replacement therapy (CRRT) (OR, 139.15; 95% CI, 1.95-9,910.14; p=0.0233) were independent predictors of mortality. Conclusion: Changes in ECMO mode and the initiation of CRRT during management were associated with mortality in patients with COVID-19 who were supported by ECMO. Patients exhibiting these factors require careful monitoring due to the potential for adverse outcomes.

• 대한소아치과학회지
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• 제33권2호
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• pp.304-310
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• 2006

본 연구는 치주질환 주요 병인균주 중의 하나인 P. intermedia를 대상으로 하여, 이 균주에서의 hemin 결합 단백질 유전자를 분리하고 염기서열을 결정하기 위하여 수행되었다. 본 연구에서는 약 5,000개의 recombinant colony들을 스크리닝하여 hemin 결합 단백질 유전자를 포함하고 있는 것으로 여겨지는 1개의 클론(pHem1)을 확인하였다. Restriction enzyme mapping 결과 pHem1의 insert DNA의 크기는 약 2.5kb이었으며 P. intermedia chromosomal DNA 내에는 hemin 결합 단백질 유전자가 single copy로 존재하였고, transcript의 크기는 약 1.8kb이었다. 분리한 pHem1 유전자는 1개의 ORF를 가지고 있으며, ORF의 크기는 2,550bp로 약 850개의 아미노산 폴리펩타이드로 구성되어 있다. 또한, pHem1 유전자는 이미 밟혀진 다른 유전자들과 상동성을 보이지 않았다. 본 연구는 P. intermedia에서의 porphyrin생리 및 hemin 획득기전을 분자생물학적으로 규명하는데 있어 중요한 의의가 있으리라 사료된다. 향후 pHem1 유전자의 특성 분석 등이 수행되어야 할 것으로 여겨진다.

• 센서학회지
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• 제22권1호
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• pp.18-27
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• 2013

Real-time monitoring is one of the prime necessities in a weapon flight test that is required for the efficient and timely collection of large amounts of high-rate sampled data acquired by an event-trigger. The wireless sensor network is a good candidate to resolve this requirement, especially considering the inhospitable environment of a weapon flight test. In this paper, we propose a priority based multi-channel MAC protocol with CSMA/CA over a single radio for a real-time monitoring of a weapon flight test. Multi-channel transmissions of nodes can improve the network performance in wireless sensor networks. Our proposed MAC protocol has two operation modes: Normal mode and Priority Mode. In the normal mode, the node exploits the normal CSMA/CA mechanism. In the priority mode, the node has one of three grades - Class A, B, and C. The node uses a different CSMA/CA mechanism according to its grade that is determined by a signal level. High grade nodes can exploit more channels and lower backoff exponents than low ones, which allow high grade nodes to obtain more transmission opportunities. In addition, it can guarantee successful transmission of important data generated by high grade nodes. Simulation results show that the proposed MAC exhibits excellent performance in an event-triggered real-time application.

• Structural Engineering and Mechanics
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• 제14권4호
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• pp.491-504
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• 2002

A state-space method is proposed to analyze the aerodynamically coupled flutter problems of long-span bridges based on the modal coordinates of structure. The theory about complex modes is applied in this paper. The general governing equation of the system is converted into a complex standard characteristic equation in a state space format, which contains only two variables. The proposed method is a single-parameter searching method about reduced velocity, and it need not choose the participating modes beforehand and has no requirement for the form of structure damping matrix. The information about variations of system characteristics with reduced velocity and wind velocity can be provided. The method is able to find automatically the lowest critical flutter velocity and give relative amplitudes, phases and energy ratios of the participating modes in the flutter motion. Moreover, the flutter analysis of Jiangyin Yangtse suspension bridge with 1385 m main span is performed. The proposed method has proved reliable in its methodology and efficient in its use.

• 한국CDE학회논문집
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• 제1권1호
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• pp.1-19
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• 1996

Non-manifold topological representations can provide a single unified representation for mixed dimensional models or cellular models and thus have a great potential to be applied in many application areas. Various boundary representations for non-manifold topology have been proposed in recent years. These representations are mainly interested in describing the sufficient adjacency relationships and too redundant as a result. A model stored in these representations occupies too much storage space and is hard to be manipulated. In this paper, we proposed a compact hierarchical non-manifold boundary representation that is extended from the half-edge data structure for solid models by introducing the partial topological entities to represent some non-manifold conditions around a vertex, edge or face. This representation allows to reduce the redundancy of the existing schemes while full topological adjacencies are still derived without the loss of efficiency. To verify the statement above, the storage size requirement of the representation is compared with other existing representations and present some main procedures for querying and traversing the representation. We have also implemented a set of the generalized Euler operators that satisfy the Euler-Poincare formula for non-manifold geometric models.

• 국제초고층학회논문집
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• 제4권4호
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• pp.271-281
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• 2015

This paper introduces detailed three-dimensional numerical analyses on a bored pile foundation for a high-rise building. A static load test was performed on a test pile and a numerical model of a single pile, which was calibrated by comparing it with the test result. The detailed numerical analysis was then conducted on the entire high-rise building foundation. Further study focused on soil pressures under the base slab of a piled raft foundation. Total seven cases with different pile numbers and raft-soil contact conditions were investigated. The design criteria of a foundation, especially settlement requirement were satisfied even for the cases with fewer piles under considerable soil pressure beneath the base slab. The bending moment for the structural design of the base slab was reduced by incorporating soil pressures beneath the base slab along with bored piles. Through the comparative studies, it was found that a more efficient design can be achieved by considering the soil pressure beneath the slab.

• 한국진공학회지
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• 제10권3호
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• pp.361-367
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• 2001

CMP(Chemical Mechanical Polishing)는 반도체 소자 제조공정 중 다층 배선구조의 평탄 경면화에 널리 이용되고 있다. 차세대 웨이퍼로 각광받는 SOI(Silicon On Insulator) 웨이퍼 제조공정 중 웨이퍼 표면 미소 거칠기를 개선하기 위해서 본 논문에서는 여러 가지 가공변수(슬러리와 연마패드)에 따른 CMP 연마능률과 표면 미소 거칠기 변화에 대해 연구하였다. 결과적으로 연마능률은 슬러리의 입자 크기가 증가할수록 이에 따라 증가하였으며, 미소 거칠기는 슬러리의 연마입자보다는 연마패드에 영향이 더욱 지배적이다. AFM(Atomic Force Microscope)에 의한 평가에서 표면 미소 거칠기가 27 $\AA$ Rms에서 0.64 $\AA$ Rms로 개선됨을 확인할 수 있었다.