• Title/Summary/Keyword: Single Plate System

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Gas Typed Digital X-ray Image Sensor Using PDP Fabrication Process (PDP공정을 이용한 가스 방식의 디지털 X-ray 영상 센서)

  • Kim, Chang Man;Kim, Si Hyung;Nam, Ki Chang;Kim, Sang Hee;Song, Kwang Soup
    • Journal of the Institute of Electronics and Information Engineers
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    • v.49 no.9
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    • pp.322-327
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    • 2012
  • Parallel-plate-type scanning sensors have been commercially used for X-ray imaging sensors. In this study, we manufactured the scan typed 1D X-ray image sensor that can be used to obtain scanning images, by using the plasma display panel (PDP) fabrication process. We fabricated drift and pixel electrodes in the glass chamber and injected Xe gas at atmospheric pressure. We evaluated the intensity of a pixel signal depending on the bias voltage on the drift electrode and investigated the characteristics of shielding effect on the single pixel using lead (Pb). The adsorption rate of X-ray photon is low (4%) on the soda lime glass (1.1mm) and the electrical signal detected on the X-ray sensor was increased in the high bias voltage. We acquired digital X-ray scanning image with our DAS (data acquisition system) and sensor scanning system.

Lysozyme Crystallization in Droplet-based Microfluidic Device (액적기반 미세유체장치에서 라이소자임 결정화)

  • Ko, Kwan-Young;Kim, In-Ho
    • Korean Chemical Engineering Research
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    • v.51 no.6
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    • pp.760-765
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    • 2013
  • Lysozyme crystallization was performed by using flow-focusing chip in droplet-based microfluidic system. Water-in-oil droplets were formed in the system and collected on petri-dish and cross type mold. Liquid-liquid reaction of lysozyme and sodium chloride occurred in the droplet and crystals were observed through microscope. Solution pH was varied as 4.8 and 7.2. Crystals of polyhedron and plate-like shape were obtained at pH 4.8, while needle structure crystals formed at pH 7.2. Lysozyme in single droplet for two pHs were crystallized with constant or decreased droplet size. However, crystals at pH 4.8 were only obtained in the droplet of which size was increased by the interaction between droplets. Droplet volume did not change at pH 7.2 and crystals formed in both droplets.

Structural health rating (SHR)-oriented 3D multi-scale finite element modeling and analysis of Stonecutters Bridge

  • Li, X.F.;Ni, Y.Q.;Wong, K.Y.;Chan, K.W.Y.
    • Smart Structures and Systems
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    • v.15 no.1
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    • pp.99-117
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    • 2015
  • The Stonecutters Bridge (SCB) in Hong Kong is the third-longest cable-stayed bridge in the world with a main span stretching 1,018 m between two 298 m high single-leg tapering composite towers. A Wind and Structural Health Monitoring System (WASHMS) is being implemented on SCB by the Highways Department of The Hong Kong SAR Government, and the SCB-WASHMS is composed of more than 1,300 sensors in 15 types. In order to establish a linkage between structural health monitoring and maintenance management, a Structural Health Rating System (SHRS) with relevant rating tools and indices is devised. On the basis of a 3D space frame finite element model (FEM) of SCB and model updating, this paper presents the development of an SHR-oriented 3D multi-scale FEM for the purpose of load-resistance analysis and damage evaluation in structural element level, including modeling, refinement and validation of the multi-scale FEM. The refined 3D structural segments at deck and towers are established in critical segment positions corresponding to maximum cable forces. The components in the critical segment region are modeled as a full 3D FEM and fitted into the 3D space frame FEM. The boundary conditions between beam and shell elements are performed conforming to equivalent stiffness, effective mass and compatibility of deformation. The 3D multi-scale FEM is verified by the in-situ measured dynamic characteristics and static response. A good agreement between the FEM and measurement results indicates that the 3D multi-scale FEM is precise and efficient for WASHMS and SHRS of SCB. In addition, stress distribution and concentration of the critical segments in the 3D multi-scale FEM under temperature loads, static wind loads and equivalent seismic loads are investigated. Stress concentration elements under equivalent seismic loads exist in the anchor zone in steel/concrete beam and the anchor plate edge in steel anchor box of the towers.

Recent Progress in Air-Conditioning and Refrigeration Research : A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2012 (설비공학 분야의 최근 연구 동향 : 2012년 학회지 논문에 대한 종합적 고찰)

  • Han, Hwataik;Lee, Dae-Young;Kim, Sa Ryang;Kim, Hyun-Jung;Choi, Jong Min;Park, Jun-Seok;Kim, Sumin
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.25 no.6
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    • pp.346-361
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    • 2013
  • This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering during 2012. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. The conclusions are as follows : (1) The research works on thermal and fluid engineering have been reviewed as groups of fluid machinery, pipes and valves, fuel cells and power plants, ground-coupled heat pumps, and general heat and mass transfer systems. Research issues are mainly focused on new and renewable energy systems, such as fuel cells, ocean thermal energy conversion power plants, and ground-coupled heat pump systems. (2) Research works on the heat transfer area have been reviewed in the categories of heat transfer characteristics, pool boiling and condensing heat transfer, and industrial heat exchangers. Researches on heat transfer characteristics included the results for natural convection in a square enclosure with two hot circular cylinders, non-uniform grooved tube considering tube expansion, single-tube annular baffle system, broadcasting LED light with ion wind generator, mechanical property and microstructure of SA213 P92 boiler pipe steel, and flat plate using multiple tripping wires. In the area of pool boiling and condensing heat transfer, researches on the design of a micro-channel heat exchanger for a heat pump, numerical simulation of a heat pump evaporator considering the pressure drop in the distributor and capillary tubes, critical heat flux on a thermoexcel-E enhanced surface, and the performance of a fin-and-tube condenser with non-uniform air distribution and different tube types were actively carried out. In the area of industrial heat exchangers, researches on a plate heat exchanger type dehumidifier, fin-tube heat exchanger, an electric circuit transient analogy model in a vertical closed loop ground heat exchanger, heat transfer characteristics of a double skin window for plant factory, a regenerative heat exchanger depending on its porous structure, and various types of plate heat exchangers were performed. (3) In the field of refrigeration, various studies were executed to improve refrigeration system performance, and to evaluate the applicability of alternative refrigerants and new components. Various topics were presented in the area of refrigeration cycle. Research issues mainly focused on the enhancement of the system performance. In the alternative refrigerant area, studies on CO2, R32/R152a mixture, and R1234yf were performed. Studies on the design and performance analysis of various compressors and evaporator were executed. (4) In building mechanical system research fields, twenty-nine studies were conducted to achieve effective design of mechanical systems, and also to maximize the energy efficiency of buildings. The topics of the studies included heating and cooling, HVAC system, ventilation, renewable energy systems, and lighting systems in buildings. New designs and performance tests using numerical methods and experiments provide useful information and key data, which can improve the energy efficiency of buildings. (5) In the fields of the architectural environment, studies for various purposes, such as indoor environment, building energy, and renewable energy were performed. In particular, building energy-related researches and renewable energy systems have been mainly studied, reflecting interests in global climate change, and efforts to reduce building energy consumption by government and architectural specialists. In addition, many researches have been conducted regarding indoor environments.

Full validation of high-throughput bioanalytical method for the new drug in plasma by LC-MS/MS and its applicability to toxicokinetic analysis

  • Han, Sang-Beom
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2006.11a
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    • pp.65-74
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    • 2006
  • Modem drug discovery requires rapid pharmacokinetic evaluation of chemically diverse compounds for early candidate selection. This demands the development of analytical methods that offer high-throughput of samples. Naturally, liquid chromatography / tandem mass spectrometry (LC-MS/MS) is choice of the analytical method because of its superior sensitivity and selectivity. As a result of the short analysis time(typically 3-5min) by LC-MS/MS, sample preparation has become the rate- determining step in the whole analytical cycle. Consequently tremendous efforts are being made to speed up and automate this step. In a typical automated 96-well SPE(solid-phase extraction) procedure, plasma samples are transferred to the 96-well SPE plate, internal standard and aqueous buffer solutions are added and then vacuum is applied using the robotic liquid handling system. It takes only 20-90 min to process 96 samples by automated SPE and the analyst is physically occupied for only approximately 10 min. Recently, the ultra-high flow rate liquid chromatography (turbulent-flow chromatography)has sparked a huge interest for rapid and direct quantitation of drugs in plasma. There is no sample preparation except for sample aliquotting, internal standard addition and centrifugation. This type of analysis is achieved by using a small diameter column with a large particle size(30-5O ${\mu}$m) and a high flow rate, typically between 3-5 ml/min. Silica-based monolithic HPLC columns contain a novel chromatographic support in which the traditional particulate packing has been replaced with a single, continuous network (monolith) of pcrous silica. The main advantage of such a network is decreased backpressure due to macropores (2 ${\mu}$m) throughout the network. This allows high flow rates, and hence fast analyses that are unattainable with traditional particulate columns. The reduction of particle diameter in HPLC results in increased column efficiency. use of small particles (<2 urn), however, requires p.essu.es beyond the traditional 6,000 psi of conventional pumping devices. Instrumental development in recent years has resulted in pumping devices capable of handling the requirements of columns packed with small particles. The staggered parallel HPLC system consists of four fully independent binary HPLC pumps, a modified auto sampler, and a series of switching and selector valves all controlled by a single computer program. The system improves sample throughput without sacrificing chromatographic separation or data quality. Sample throughput can be increased nearly four-fold without requiring significant changes in current analytical procedures. The process of Bioanalytical Method Validation is required by the FDA to assess and verify the performance of a chronlatographic method prior to its application in sample analysis. The validation should address the selectivity, linearity, accuracy, precision and stability of the method. This presentation will provide all overview of the work required to accomplish a full validation and show how a chromatographic method is suitable for toxirokinetic sample analysis. A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method developed to quantitate drug levels in dog plasma will be used as an example of tile process.

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Investigation and Analysis on the Surface Morphology of Roof-Top Photovoltaic System (평지붕 설치 태양광시스템의 표면형태 조사·분석)

  • Lee, Eung-Jik
    • Journal of the Korean Solar Energy Society
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    • v.36 no.4
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    • pp.57-65
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    • 2016
  • Domestic photovoltaic system for roof-top is installed towards the south at an angle of 20 to 35 degrees and the shape of PV array is divided into two kinds; a plane shape and a curved shape. This paper aims to understand an actual condition of PV facility and strengths and weaknesses of support structure production and installation and to consider the best PV surface shape by analyzing theoretical logics of these two surface shapes and architectural perspective-based realistic case studies. This study targeted 98 facilities including common houses, public institutions and education institutions. In common houses, all of 59 PV facilities have a plane surface. In public institutions, 7 of 15 PV facilities have a curved array surface and 8 PV facilities have a plane surface. In education institutions, also, 14 of 24 PV facilities have a plane array surface and 10 PV facilities have a curved surface. Most of 98 facilities have a flat roof supporting shape. However, it was found that the curved shape wasn't positive for PV generation due to the change of radial density and it was at least 10 % more expensive to produce its structure. Also, domestic general large single-plate PV facilities have problems of harmony with buildings and wind load. Therefore, it is considered that for fixed-type roof-top PV, a plane PV array shape is good for optimum generation and economic efficiency and a parallel array structure on the roof surface is favorable to wind load and snow load without being a hindrance to the building facade.

A Study on the Construction of Littman and Littrow Type Tunable Diode Laser Systems (Littman 및 Littrow 타입 파장가변 반도체 레이저의 제작에 관한 연구)

  • Baek, Woon-Sik
    • Korean Journal of Optics and Photonics
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    • v.17 no.3
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    • pp.273-277
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    • 2006
  • In this paper, we constructed the Littman type and fixed Littrow type tunable external-cavity diode laser systems. The laser output, which is the 0th-order diffracted beam from the diffraction grating in an external cavity, was the single longitudinal mode. Its FWHM was measured as less than 9MHz. With the diode driving current of 140mA and operating temperature of $25^{\circ}C$, the coarse tuning range of 5.375nm was measured for the Littman type, and of 13.65nm was measured for the fixed Littrow type. A fine tuning experiment in which an external mirror was rotated by a PZT driven by a sawtooth wave was performed, and its tuning range of 0.042nm was measured for both types. The fixed Littrow type tunable external-cavity diode laser system was an improvement on the conventional Littrow type tunable laser system in which the output direction varies due to the grating embedded in the mirror plate.

The Genotoxicity Study of Molinate, an Herbicide, in Bacterial Reversion, in vitro and in vivo Mammalian System

  • Kim, Youn-Jung;Ryu, Jae-Chun
    • Molecular & Cellular Toxicology
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    • v.2 no.3
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    • pp.176-184
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    • 2006
  • The controversy on genotoxicity of molinate, an herbicide, has been reported in bacterial system, and in vitro and in vivo mammalian systems. To clarify the genotoxicity of molinate, we performed bacterial gene mutation test, in vitro chromosome aberration and mouse lymphoma $tk^{+/-}$ gene assay, and in vivo micronucleus assay using bone marrow cells and peripheral reticulocytes of mice. In bacterial gene mutation assay, no mutagenicity of molinate ($12-185{\mu}g/plate$) was observed in Salmonella typhimurium TA 98, 100, 1535 and 1537 both in the absence and in the presence of S-9 metabolic activation system. The clastogenicity of molinate was observed in the presence ($102.1-408.2\;{\mu}g/mL$) of metabolic activation system in mammalian cell system using Chinese hamster lung fibroblast. However, no clastogenicity was observed in the absence ($13.6-54.3\;{\mu}g/mL$) of metabolic activation system. It is suggested that the genotoxicity of molinate was derived some metabolites by metabolic activation. Molinate was also subjected to mouse lymphoma L5178Y $tk^{+/-}$ cells using microtiter cloning technique. In the absence of S-9 mixture, mutation frequencies (MFs) were revealed $1.4-1.9{\times}10^{-4}$ with no statistical significance. However, MFs in the presence of metabolic activation system revealed $3.2-3.4{\times}10^{-4}$ with statistical significance (p<0.05). In vivo micronucleus (MN) assay using mouse bone marrow cells, molinate revealed genotoxic potential in the dose ranges of 100-398 mg/kg of molinate when administered orally. Molinate also subjected to acridine orange MN assay with mouse peripheral reticulocytes. The frequency of micronucleated reticulocytes (MNRETs) induced 48 hr after i.p. injection at a single dose of 91, 182 and 363 mg/kg of molinate was dose-dependently increased as $10.2{\pm}4.7,\;14.6{\pm}3.9\;and\;28.6{\pm}6.3\;(mean{\pm}SD\;of\;MNRETs/2,000\;reticulocytes)$ with statistical significance (p<0.05), respectively. Consequently, genotoxic potential of molinate was observed in in vitro mammalian mutagenicity systems only in the presence of metabolic activation system and in vivo MN assay using both bone marrow cells and peripheral reticulocytes in the dose ranges used in this experiment. These results suggest that metabolic activation plays a critical role to express the genotoxicity of molinate in in vitro and in vivo mammalian system.

Experimental Study of SBLOCA Simulation of Safety-Injection Line Break with Single Train Passive Safety System of SMART-ITL (SMART-ITL 1 계열 피동안전계통을 이용한 안전주입배관 파단 소형냉각재상실사고 모의에 대한 실험적 연구)

  • Ryu, Sung Uk;Bae, Hwang;Ryu, Hyo Bong;Byun, Sun Joon;Kim, Woo Shik;Shin, Yong-Cheol;Yi, Sung-Jae;Park, Hyun-Sik
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.40 no.3
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    • pp.165-172
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    • 2016
  • An experimental study of the thermal-hydraulic characteristics of passive safety systems (PSSs) was conducted using a system-integrated modular advanced reactor-integral test loop (SMART-ITL). The present passive safety injection system for the SMART-ITL consists of one train with the core makeup tank (CMT), the safety injection tank, and the automatic depressurization system. The objective of this study is to investigate the injection effect of the PSS on the small-break loss-of-coolant accident (SBLOCA) scenario for a 0.4 inch line break in the safety-injection system (SIS). The steady-state condition was maintained for 746 seconds before the break. When the major parameters of the target value and test results were compared, most of the thermal-hydraulic parameters agreed closely with each other. The water level of the reactor pressure vessel (RPV) was maintained higher than that of the fuel assembly plate during the transient, for the present CMT and safety injection tank (SIT) flow rate conditions. It can be seen that the capability of an emergency core cooling system is sufficient during the transient with SMART passive SISs.

Catadioptric Omnidirectional Optical System Using a Spherical Mirror with a Central Hole and a Plane Mirror for Visible Light (중심 구멍이 있는 구면거울과 평면거울을 이용한 가시광용 반사굴절식 전방위 광학계)

  • Seo, Hyeon Jin;Jo, Jae Heung
    • Korean Journal of Optics and Photonics
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    • v.26 no.2
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    • pp.88-97
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    • 2015
  • An omnidirectional optical system can be described as a special optical system that images in real time a panoramic image with an azimuthal angle of $360^{\circ}$ and the altitude angle corresponding to the upper and lower fields of view from the horizon line. In this paper, for easy fabrication and compact size, we designed and fabricated a catadioptric omnidirectional optical system consisting of the mirror part of a spherical mirror with a central hole (that is, obscuration), a plane mirror, the imaging lens part of 3 single spherical lenses, and a spherical doublet in the visible light spectrum. We evaluated its image performance by measuring the cut-off spatial frequency using automobile license plates, and the vertical field of view using an ISO 12233 chart. We achieved a catadioptric omnidirectional optical system with vertical field of view from $+53^{\circ}$ to $-17^{\circ}$ and an azimuthal angle of $360^{\circ}$. This optical system cleaniy imaged letters on a car's front license plate at the object distance of 3 meters, which corresponds to a cut-off spatial frequency of 135 lp/mm.