• Tuberculosis and Respiratory Diseases
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• v.76 no.4
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• pp.184-187
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• 2014

A nasal-type extranodal natural killer/T-cell lymphoma is considered an aggressive form of non-Hodgkin's lymphoma, with approximately half of all patients relapsing during the follow-up period, and most relapses occurring within the first 2 years of remission. Here we report an unusual case of a 42-year-old man who experienced recurrence in single pleura after 8 years of remission.

• 한국신재생에너지학회:학술대회논문집
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• 2008.05a
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• pp.572-575
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• 2008

Flow-field design has much influence over the performance of proton exchange membrane fuel cell (PEMFC) because it affects the pressure magnitude and distribution of the reactant gases. To obtain the pressure magnitude and distribution of reactant gases in four kinds of flow-field designs without additional measurement equipment, computational fluid dynamics (CFD) analysis was performed. After the CFD analysis, the performance values of PEMFC according to the flow-field configurations were measured via a single cell test. As expected, the pressure differences due to different flow-field configurations were related to the PEMFC performance because the actual performance results showed the same tendency as the results of the CFD analysis. A large pressure drop resulted in high PEMFC performance. So, the single serpentine configuration gave the highest performance. On the other hand, the parallel flow-field configuration gave the lowest performance because the pressure difference between inlet and outlet was the lowest.

• 한국신재생에너지학회:학술대회논문집
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• 2007.06a
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• pp.161-165
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• 2007

Recently by the development of the electronic engineering technology various mobile devices are developed. But their operation time need to be extended although capacity of the batteries are limited. We focused our attention to the portable SOFC system. Because SOFC has the high efficiency and a lot of strongness in comparison with other kinds of fuel cells. In addition they can be built as a self/non-reformable system and single/dual chamber system. So We evaluated some types of SOFC theoretically, and compared the results from the fuel and performance efficiency point of view.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.7
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• pp.991-994
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• 2000

Single cell of an indigenous phototrophic bacterium, Rhodovulum sulfidophilum, was incorporated in commercial fish feed for Oreochromis niloticus. The bacterial cell was analyzed for nutritional value and tested for toxicity and acceptability as an aquaculture feed supplement. The results showed higher survival rate and significantly higher growth rate (p<0.001) in O. niloticus fed with the bacteria incorporated fish feed. It is suggested that R sulfidophilum can be utilized as an aquaculture feed supplement.

• Journal of Mechanical Science and Technology
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• v.20 no.3
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• pp.297-309
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• 2006

This paper deals with a novel structure for single-cell characterization which makes use of bimorph micro thermal actuators combined with electrical sensor device and integrated microfluidic channel. The goal for this device is to capture and characterize individual biocell. Quantitative and qualitative characteristics of bimorph thermal actuator were analyzed with finite element analysis methods. Furthermore, optimization for the dimension of cantilevers and integrated parallel probe systems with microfluidic channels is able to be realized through the virtual simulation for actuation and the practical fabrication of prototype of probes. The experimental value of probe deflection was in accordance with the simulated one.

• The Journal of Korea Robotics Society
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• v.11 no.3
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• pp.133-139
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• 2016

Increasing interest of human health, building bio-database (Bio DB) has been become a hot issue in life science. Consequently, Single Cell Analysis (SCA) which can explain biodiversity of lives has been a significant factor for building Bio DB. In numerous studies from these analyses, they have been showed that mechanical properties of cells can serve explanation of biological heterogeneity and criterion of disease states. Therefore, measuring mechanical properties of cells have great potential to be used in bio-medical applications. However, traditionally, many researchers have undergone difficult and time consuming work because handling small sized cells usually requires high-skilled technique. Thus, this paper shows robotized stiffness measurement technique using fixed ended beam sensor, precision motorized stage and substrate which have wall structure.

• Proceedings of the Korea Society of Environmental Biology Conference
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• 2002.11a
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• pp.145-153
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• 2002

유해 화학 물질류에 의해 오염된 해양 환경 시료의 환경독성 수준을 평가하기 위하여 다양한 화학물질에 대해 민감성이 우수한 생물학적 독성평가기법을 개발 하고자하였다. 지속성 유기오염 물질 중 다환 방향 족 탄화수소(PAHs)를 처리한 광어(Conger myriaster)와 개조개(Saxidomus pupurata)의 DNA 손상정도를 single cell gel electrophoresis assay(comet assay)를 통해 분석하였다. PAHs 중 광양만에서 높은 농도로 검출되는 benzo(a)pyrene을 농도별(0, 10, 50, 100 ppb)로 처리한 후 2일과 4일에 광어의 혈액세포와 개조개의 근육세포를 채취해 comet assay를 실시하였다. benso(a)pyrene에 대한 DNA 손상정도를 처리된 농도와 생물종에 따라 다르게 나타났는데 광어의 혈액세포는 2일에 가장 DNA 손상정도가 높았고, 4일에는 회복되는 경향을 나타냈다. 개조개의 근육세포는 시간이 지나면서 DNA 손상정도가 증가하는 경향을 보였다. 이와 같은 결과는 comet assay 기법이 유해 화학물질로 오염된 해양생물 종의 환경독성을 검색하는 유용한 수단이 될 수 있음을 보여준다.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.151-152
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• 2006

Multi-hop system has advantage of low power consumption, improved cell capacity, and enlarged service coverage. Most of previous researches show that multi-hop relaying beyond dual-hop relaying does not improve system performance significantly. This leads most researches are focused on dual-hop relaying system. In this paper, we propose an optimal boundary condition to support maximal data rate for fluctuation of traffic load in single cell dual-hop relay system.

• Proceedings of the KIPE Conference
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• 2015.07a
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• pp.373-374
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• 2015

This paper proposes a dynamic thermo-electric model that links electrical parameters with thermal parameters. In this model, the irradiance and ambient temperature are used to calculate the cell temperature based on a four-layer model that includes the PV cell and surround materials. The calculated cell temperature is then used in the electrical model to accurately adjust the PV electrical characteristics. Dynamic PV characteristics, parallel capacitive and series inductive components, are added to the conventional single-diode model. The results show the effectiveness of this model rather than other conventional models of a PV panel.

• Molecules and Cells
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• v.46 no.2
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• pp.86-98
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• 2023

The genome is almost identical in all the cells of the body. However, the functions and morphologies of each cell are different, and the factors that determine them are the genes and proteins expressed in the cells. Over the past decades, studies on epigenetic information, such as DNA methylation, histone modifications, chromatin accessibility, and chromatin conformation have shown that these properties play a fundamental role in gene regulation. Furthermore, various diseases such as cancer have been found to be associated with epigenetic mechanisms. In this study, we summarized the biological properties of epigenetics and single-cell epigenomic profiling techniques, and discussed future challenges in the field of epigenetics.