• Title/Summary/Keyword: Simultaneous Model

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Profiling Approach for the Choice between Speculation and Postponement Strategy in Supply Chain Management (공급사슬관리의 예측전략과 지연전략 선택을 위한 프로파일링 접근법)

  • Kang, Sung-Wook;Kim, Gyu-Bae
    • Journal of Distribution Science
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    • v.12 no.4
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    • pp.47-54
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    • 2014
  • Purpose - The postponement strategy, which delays the form, place, and production of products as late as possible, has been widely considered as a competitive supply chain management scheme in an era of mass customization and modular manufacturing. An interesting business phenomenon is that not all manufacturing/logistics firms choose the postponement strategy. Given that postponement is a counter-measure to speculation, which has some advantages under certain environments, the current imprudent inclination toward the postponement strategy may cause firms to lose the potential of the speculation strategy, an alternative strategy in supply chain management. Building on the logistics and manufacturing literature, this study examines characteristics of two contrasting strategies, postponement and speculation, and major factors favoring each strategy. Research design, data, and methodology - We apply the profiling approach to two business cases, HP printer and LG mobile phone. The profiling approach is a method of choosing a particular strategy aligned with environmental factors. While various approaches have been used to check the fit between a business strategy and environmental factors, the literature on manufacturing strategy and logistics has commonly adopted the profiling approach. Major factors used in profiling variables are derived from the literature. Two samples, HP printer and LG mobile phone, are selected, because they represent major characteristics appropriate for each strategy. The profiling is based on data from semi-organized interviews with managers. Results - The profiling approach shows that the postponement strategy is a suitable one for HP printers. Most factors, such as product life cycle, large production volume, low-price, product value, and monetary density, support delaying end products until as late as possible. Despite some exceptions, such as delivery time and economy of scale, our analysis states that the overall profile of HP printer is favorable for the postponement strategy. On the other hand, LG mobile phone may adapt the speculation strategy. Although it has large production volume and low delivery frequency, most characteristics support the speculation strategy for this product. An interesting finding is that, despite common perception that advanced technology products such as mobile telephones favor the postponement strategy, profiling proposes the speculation strategy for this product. Conclusions - Our analysis shows that speculation is not the universal option for supply chain management, and that, when choosing a specific strategy, one should consider many factors simultaneously. A major implication of our work is to emphasize the role of environmental factors such as supply chain variables in choosing an inventory strategy, and the importance of fit rather than solely strategic orientation. A theoretical contribution is to demonstrate the benefit of the simultaneous consideration of business variables in choosing specific strategies. For practitioners, our work leads us to consider the existence and the potential of speculation as a counter-measure to postponement. In addition, the comprehensive framework in this research may be instantly used in examining a practical strategy.

Study of literature on the Trigeminal Neuralgia for cooperative treatment of Oriental and Occidental medicine (韓.洋方 協診治療를 위한 三叉神經痛의 文獻的 硏究)

  • Sung, Byung-Gon;Oh, Chun-Keun;Lim, Kyu-Sang
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.13 no.2
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    • pp.112-139
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    • 2000
  • I examined and referred to literatures of every generations on the nicknames, causes, herb medications and acupucture treatments of ptosis(上胞下垂). And then the results were obtained as follows. We've compared and analyzed Occidental and Oriental medical causes, symptoms and treatments of Primary trigeminal neuralgia and wanted to get better effects by a cooperative analysis. So the examination and analysis of the recent treatment tendency and reference bibliography show the following results. 1. Trigeminal neuralgia is nerve systematic disease appearing in the distribution scope of trigeminal nerve. It's characterized by extreme pain accompanying with a repeated and simultaneous fit from several seconds to 1-2 minutes. 2. Though there are many hypothesis on the trigeminal neuralgia, but now many doctors agree that when trigeminal nerve is under the local out of sheath conditions resulting from receiving a chronic stimulus, and the nucleus of trigeminal nerve fire, owing to decrease of pain control function and abnormal occurrence of action potential, it would be appeared. 3. The Oriental medical name of trigeminal neuralgia is generally Dootong, Doopoong, Myuntong, Pyundootong, Pyundoopoong, and Myuntong is the nearest in Occidental medicine. 4. The Oriental medical cause of trigeminal neuralgia is usually divided into Wekam and Naesang. The first one is caused by Poonghan, Poongyul, Damhwa and wicked energy enter into the body, the mechanical energy is obstructed and can't move any more, so the pain appears by them. The other cause is the hurt by emotion. And it would be loss of the transportain of liver and obstructed, so result into Kanwulhwahwa, Kanpoongnaedong and the pain appears. 5. There are two methods of curing trigeminal neuralgia. As a medication, primary method is prescribing Carbamazepine and the second is using Phenytoin or Baclofen. And as a operation, Drug injection of trigeminal nerve, Amputation of branches of trigeminal nerve, Retrogasserian glycerol rhizotomy, Radiofrequency gangliolysis, Neurovascular decompression can be used. 6. There are several herb medicines for Trigeminal neuralgia. First, Chungung is good for Hwaejeetong, Keopoongjedam, Hwalhyuljeetong. Second, Jeongal, Jiryong, Okong is used for Sikpoonghekyung, Tongkyungjeetong. Third, Baekjee, Sesin, Cheonma, Manhyungja is efficacious in Sinonhepyo. Sanpoongjeetong. Fourth, for falling of liver's Wulhwa, Yongdamcho, Hyungge, Kukwha can be used. And also Saengjihwang, Hwangkm is good for going down the fever of Yangmyungwiyul and finally, Baekkangjam. Moryu can be effective for Jaumjamyang, Haekyungjitong. The other medicines can be used as assistant analgesics, and it also efficacious. 7. Generally the points of pain on the face and the points of Soyangkyung and Yangmyungkyung is used for Acupuntual therapy, because the two meridians passed on the face. Hakwan. Sabaek, Kwanryo, Keoryo, Hyubkeo, Taeyang, Jeechang, Younghyang, Eoyo, Chanjuk. Yangbaek. Sajukkong. Dooyoo, Kwangsangjum, Sengjang, Poongjee is used for taking near point and Joksamlee, Naejung, Habkok is used for taking distant point. 8. Dansam or Danggui injection which have a effect for Hwalhyulhwaeo, Sokyunghwalak and Vit B1, Vit B2, Vit B12, $2\%$ Hydrochloroprocaine, $1\%$ Lidocaine injection to pain point for local analgesics had so good effect. And external application and moxibustion are used for another treatment. 9. It proved that through mouse model, both Herb medication group and Drug medication group are efficacious for trigeminal neuralgia similarly and also the cooperative medication group shows more effective result than the only drug medication group.

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An Analysis of the Impacts of FDI Types on CO2 Emissions - Focus on Scale Effects and Technique Effects - (FDI 유형별 CO2 배출량에 미치는 영향 분석 - 규모효과와 기술효과를 중심으로 -)

  • Hwang, Yun-Seop;Park, Junghoon;Lee, Sang Whi
    • International Commerce and Information Review
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    • v.17 no.3
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    • pp.379-402
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    • 2015
  • The purpose of this study is to determine whether there is a significant difference in impacts decomposed into scale effects and technique effects on $CO_2$ emissions between Greenfield FDI and M&A FDI flows into Korean manufacturing sectors, ultimately leading to clarify the relationship between FDI and environmental pollution. To this end, the research constructed a simultaneous model to analyze coincidental relationship of influence and interactions between each variable. Archival data, spanning the 15 years period from 1995 to 2009, is industry-level panel data on 13 Korean manufacturing sectors, and it is empirically analyzed with three-stage least squares (3SLS) method. Key findings can be summarized into two parts. First of all, Greenfield FDI has a greater impact on increasing industrial gross output, resulting in more $CO_2$ emissions than M&A FDI through scale effects. Secondly, technique effects of FDI have a bigger impact on $CO_2$ emissions than scale effects, implying that this inflow of FDI into Korea contributes positively to the reduction of $CO_2$ emissions. These findings are expected to play a meaningful role in establishing FDI policies with consideration of the environment by giving the implication that different incentives for each FDI type should be considered to maximize the effect of environmental protection.

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Enhancement of Performance of Shell and Tube Heat Exchanger Using Pertinent Leakage Flow Between Baffle and Tube Bundles (배플과 관군간의 적정 누설유동을 이용한 쉘-관 열교환기의 성능향상)

  • Nguyen, Van Hap;Lee, Geun Sik
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.39 no.3
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    • pp.223-229
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    • 2015
  • In this study, the effects of the leakage flow between the baffle and tube bundles on the performance of a shell and tube heat exchanger (STHE) were examined using the commercial software ANSYS FLUENT v.14. A computational fluid dynamics model was developed for a small STHE with five different cases for the ratio of the leakage cross-sectional area to the baffle cross-sectional area, ranging from 0 to 40%, in order to determine the optimum leakage flow corresponding to the maximum outlet temperature. Using fixed tube wall and inlet temperatures for the shell side of the STHE, the flow and temperature fields were calculated by increasing the Reynolds number from 4952 to 14858. The present results showed that the outlet temperature, pressure drop, and heat transfer coefficient were strongly affected by the leakage flow, as well as the Reynolds number. In contrast with a previous researcher's finding that the leakage flow led to simultaneous decreases in the pressure drop and heat transfer rate, the present study found that the pertinent leakage flow provided momentum in the recirculation zone near the baffle plate and thus led to the maximum outlet temperature, a small pressure drop, and the highest heat transfer rate. The optimum leakage flow was shown in the case with a ratio of 20% among the five different cases.

Deterministic Lateral Displacement as a Function of Particle Size Using a Piecewise Curved Planar Interdigitated Electrode Array (다중예각 평면 교차전극을 이용한 입자 크기에 따른 측면방향 변위)

  • Han, Song-I;Joo, Young-Dong;Han, Ki-Ho
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.3
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    • pp.241-249
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    • 2012
  • This paper presents the lateral displacement of a particle passing over a planar interdigitated electrode array at an angle as a function of particle size. The lateral displacement was also measured as a function of the angle between the electrode and the direction of flow. A simplified line charge model was used for numerical estimation of the lateral displacement of fluorescent polystyrene (PS) beads with three different diameters. Using the lateral displacement as a function of particle size, we developed a lateral dielectrophoretic (DEP) microseparator, which enables the continuous discrimination of particles by size. The experiment using an admixture of 3-, 5-, and $10-{\mu}m$ PS beads showed that the lateral DEP microseparator could continuously separate out 99.86% of the $3-{\mu}m$ beads, 98.82% of the $5-{\mu}m$ beads, and 99.69% of the $10-{\mu}m$ beads. The lateral DEP microseparator is thus a practical device for the simultaneous separation of particles according to size from a heterogeneous admixture.

Association of CAST Gene Polymorphisms with Carcass and Meat Quality Traits in Chinese Commercial Cattle Herds

  • Li, Jiao;Zhang, Lu-Pei;Gan, Qian-Fu;Li, Jun-Ya;Gao, Hui-Jiang;Yuan, Zheng-Rong;Gao, Xue;Chen, Jin-Bao;Xu, Shang-Zhong
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.11
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    • pp.1405-1411
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    • 2010
  • Calpastatin (CAST), an endogenous inhibitor of the calpains, plays an important role in post-mortem tenderization of meat. The objectives of this study were to investigate single nucleotide polymorphisms (SNPs) in the bovine CAST gene and association with carcass and meat quality traits. A total of 212 cattle from commercial herds were tested in this study including 2 pure introduced breeds, 4 cross populations, and 3 pure Chinese native breeds. Five SNPs were identified at position 2959 (A/G), 2870 (G/A), 3088 (C/T), 3029 (G/A) and 2857 (C/T) in the CAST gene (GenBank Accession No. AF159246). Allele frequencies of SNP2959 and SNP2870 were 0.701 (A) and 0.462 (A), respectively. A general linear model was used to evaluate the associations between the two markers and 7 traits. The results showed that both SNP2959 and SNP2870 were significantly (p<0.01) associated with the Warner-Bratzler shear force (WBSF), while they had no significant association with the other 6 traits in the whole population. However, in Chinese native pure breeds, only SNP2870 had significant association with WBSF (p<0.05). The simultaneous analysis of two-marker genotype effects indicated animals containing the A/G haplotype (A for SNP2959 and G for SNP2870) tended to have lower shear force than those containing the G/A haplotype, and, especially, animals homozygous for the A/G haplotype had approximately 2 kg lower shear force than those homozygous for the G/A haplotype (p<0.01). These results suggested that both markers may be effective for the marker-assisted selection of meat quality traits in Chinese commercial herds, especially SNP2870 which can be used for Chinese native cattle.

Detecting Shared Resource Usage Errors with Global Predicates (광역조건식에 의한 공유자원 접근오류 검색)

  • Lee, Eun-Jeong;Yun, Gi-Jung
    • Journal of KIISE:Software and Applications
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    • v.26 no.12
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    • pp.1445-1454
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    • 1999
  • 광역 조건식의 계산은 분산 프로그램의 수행을 테스트 또는 디버깅하기 위한 방법으로 활 발히 연구되고 있다. 이제까지 주로 연구된 광역조건식은 AND 또는 OR 광역 조건식 등이 있는데, 특히 AND 광역 조건식은 분산 프로그램의 동시적 조건을 표현하는데 유용하여 효율적인 검색 알고리즘이 활발히 연구되었다. 분산프로그램의 수행오류로서 공유자원의 배타적 접근조건은 가장 중요하고 일반적인 경우라 할 수 있다. 본 논문에서는 XOR 연산을 이용하여 공유자원 프로그램의 오류 검색을 위한 광역조건식을 기술하는 방식에 대해 제안하였다. XOR 연산을 이용한 광역 조건식은 연산자 중 많아야 하나의 지역조건식만이 참일 때 전체 조건식이 참이 되는데 이러한 성질은 여러 프로세스 중 한번에 하나만이 공유자원에 배타적으로 접근할 수 있는 조건을 표현하는데 매우 유용하다. n 개의 프로세스로 이루어진 분산프로그램에서 한개의 공유자원에 대한 배타적 접근 조건을 기술하기 위해서 AND로 연결된 광역조건식을 이용하면 O(n2)개의 광역 조건식이 필요한데 반해 XOR 연산으로는 하나의 조건식으로 나타낼 수 있다. 더구나 XOR 연산을 이용한 광역조건식은 최근 소개된 겹치는 구간의 개념을 활용하면 매우 간단하게 검색할 수 있다. 본 논문에서는 겹치는 구간을 찾는 검색 알고리즘을 소개하고 증명하였다.Abstract Detecting global predicates is an useful tool for debugging and testing a distributed program. Past research has considered several restricted forms of predicates, including conjunctive or disjunctive form of predicates. Especially, conjunctive predicates have attracted main attention not only because they are useful to describe simultaneous conditions in a distributed program, but also because it is possible to find algorithms to evaluate them within reasonable time bound. Detecting errors in accessing shared resources are the most popular and important constraints of distributed programs. In this paper, we introduced an exclusive OR predicates as a model of global predicates to describe shared resource conditions in distributed programs. An exclusive OR predicate holds only when at most one operand is true, which is useful to describe mutual exclusion conditions of distributed programs where only one process should be allowed to access the shared resource at a time. One exclusive OR predicate is enough to describe mutual exclusion condition of n processes with one shared resource, while it takes O(n2) conjunctive predicates. Moreover, exclusive OR condition is easily detectable using the concept of overlapping intervals introduced by Venkatesan and Dathan. An off-line algorithm for evaluating exclusive OR global predicates is presented with a correctness proof.

Influence of Fimasartan (a Novel $AT_1$ Receptor Blocker) on Catecholamine Release in the Adrenal Medulla of Spontaneously Hypertensive Rats

  • Lim, Hyo-Jeong;Lee, Seog-Ki;Lim, Dong-Yoon
    • The Korean Journal of Physiology and Pharmacology
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    • v.17 no.1
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    • pp.99-109
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    • 2013
  • The aim of this study was to determine whether fimasartan, a newly developed $AT_1$ receptor blocker, can affect the CA release in the isolated perfused model of the adrenal medulla of spontaneously hypertensive rats (SHRs). Fimasartan (5~50 ${\mu}M$) perfused into an adrenal vein for 90 min produced dose- and time-dependently inhibited the CA secretory responses evoked by ACh (5.32 mM), high $K^+$ (56 mM, a direct membrane depolarizer), DMPP (100 ${\mu}M$) and McN-A-343 (100 ${\mu}M$). Fimasartan failed to affect basal CA output. Furthermore, in adrenal glands loaded with fimasartan (15 ${\mu}M$), the CA secretory responses evoked by Bay-K-8644 (10 ${\mu}M$, an activator of L-type $Ca^{2+}$ channels), cyclopiazonic acid (10 ${\mu}M$, an inhibitor of cytoplasmic $Ca^{2+}$-ATPase), and veratridine (100 ${\mu}M$, an activator of $Na^+$ channels) as well as by angiotensin II (Ang II, 100 nM), were markedly inhibited. In simultaneous presence of fimasartan (15 ${\mu}M$) and L-NAME (30 ${\mu}M$, an inhibitor of NO synthase), the CA secretory responses evoked by ACh, high $K^+$, DMPP, Ang II, Bay-K-8644, and veratridine was not affected in comparison of data obtained from treatment with fimasartan (15 ${\mu}M$) alone. Also there was no difference in NO release between before and after treatment with fimasartan (15 ${\mu}M$). Collectively, these experimental results suggest that fimasartan inhibits the CA secretion evoked by Ang II, and cholinergic stimulation (both nicotininc and muscarinic receptors) as well as by membrane depolarization from the rat adrenal medulla. It seems that this inhibitory effect of fimasartan may be mediated by blocking the influx of both $Na^+$ and $Ca^{2+}$ through their ion channels into the rat adrenomedullary chromaffin cells as well as by inhibiting the $Ca^{2+}$ release from the cytoplasmic calcium store, which is relevant to $AT_1$ receptor blockade without NO release.

PHOTOMETRIC SOLUTIONS AND SPOT MODEL OF THE CONTACT BINARY AB ANDROMEDAE (접촉쌍성 AB Andromedae의 측광해와 흑점모델)

  • Lee, Jae-Woo;Kim, Chun-Hwey;Han, Won-yong;Jin, Ho;Oh, Kyu-Dong
    • Journal of Astronomy and Space Sciences
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    • v.20 no.2
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    • pp.123-132
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    • 2003
  • We performed CCD photometric observations of the W-type contact binary AB And for 10 nights from November 1995 to December 1999 using the 61-cm reflector and BVR filters at Sobaeksan Optical Astronomy Observatory. From our observations, the seasonal light curves of AB And for 1995, 1996 and 1999 were completed and 8 new times of minimum light were determined. Newly obtained light curves show that strong light variations occurred in AB And during the past five years. We adopted the 1996 light curves as reference ones and obtained the photometric solutions of them with contact mode in the Wilson-Devinney binary code. Assuming such light variations were produced by the existence of a star spot (or star spots) in the analysis, we derived the system parameters and analyzed the 1995 and 1999 light curves by adjusting only the spot parameters. As the results, we interpreted that those light variations are produced by the simultaneous existence of a hot spot and a cool spot on the secondary. We could infer that the hot spot on the secondary is produced due to mass exchange between the components suggested by Lee (1999).

Removal of Endocrine Disrupting Chemicals in Wastewater by Nitrifying Sludge (질산화 슬러지에 의한 폐수 중의 내분비계 장애물질 제거)

  • Lim, Kyoung Jo;Hong, Soon Ho;Chung, Jin Suk;Yoo, Ik-Keun
    • Korean Chemical Engineering Research
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    • v.47 no.6
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    • pp.775-780
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    • 2009
  • The efficacy of nitrifying sludge existed in biological nutrient removal process was examined for possible removal of endocrine disrupting chemical(EDC) in the effluent of wastewater treatment plant. Some of ammonia oxidizing bacteria causes ammonia oxidation mediated by ammonia monooxygenase(AMO) activity, which has low substrate specificity resulting in cometablic degradation of several chemicals. In this study, the removal of three model EDCs such as bisphenol A(BPA), nonylphenol(NP) and dibutyl phthalate(DBP) was studied in batch cultures using nitrifying sludge, BOD-oxidizing sludge with low nitrifying activity, and sterilized sludge. Nitrifying sludge showed higher initial removal rates in all batches of three EDCs when it was fed with ammonium as an energy source. The acclimation time was required for the removal of EDCs in batches using BOD-oxidizing sludge or nitritefed nitrifying sludge. That retardation seemed to attribute to the slow growth of cells using the EDCs while ammonium-fed nitrifying sludge could degrade EDCs through simultaneous cooxidation with ammonia oxidation. Sterilized sludge was also tested under the same conditions in order to find the contribution of physical adsorption to the removal of EDCs. About 10~20% of initial EDCs dose was removed when using sterilized sludge. Thus the biological activity is likely to play major role for the degradation of BPA, NP, and DBP rather than the physical adsorption from wastewater.