• Bulletin of the Korean Chemical Society
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• v.27 no.10
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• pp.1604-1608
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• 2006

A simple and efficient cloud point extraction-spectrofluorimetric method for the determination of thiamine in human urine is proposed. The procedure is based on the oxidation of thiamine with ferricyanide to form thiochrome, its extraction to Triton X-114 micelles and spectrofluorimetric determination. The variables affecting oxidation of thiamine, extraction and phase separation were studied and optimized. Under the experimental conditions used, the calibration graphs were linear over the range 2.5-1000 ng $mL^{-1}$. The limit of detection was 0.78 ng $mL^{-1}$ of thiamine and the relative standard deviation for 5 replicate determinations of thiamine at 400 ng $mL^{-1}$ concentration level was 2.42%. Average recoveries between 93-107% were obtained for spiked samples. The proposed method was applied to the determination of thiamine in human urine.

• Proceedings of the KSPS conference
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• 2002.11a
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• pp.141-144
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• 2002

The relations between words intelligibility and sentences intelligibility were tested on adults with cerebral palsy(athetoid type). Intelligibility is used as an important evaluation value in the field of diagnosis and therapy of dysarthric patients. In order to develop one syllable phonetic contrast intelligibility test using specific phonetic contrasts, the correlation with sentences intelligibility was tested to find out the validity. Pearson's simple correlation coefficient was .83 that shows a high correlation. Also, comparing the range and standard deviation given by seven evaluators on each subject, it was shown that when evaluating patients of moderate intelligibility, words intelligibility was more reliable than sentences intelligibility.

• Phonetics and Speech Sciences
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• v.5 no.1
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• pp.3-10
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• 2013

This study proposes a method to measure mental fatigue using speech technology, which has not been used in previous research and is easier than existing complex and difficult methods. It aims at establishing a relationship between the human voice and mental fatigue based on experiments to measure the influence of mental fatigue on the human voice. Two monotonous tasks of simple calculation such as finding the sum of three one digit numbers were used to measure the feeling of monotony and two sets of subjective questionnaires were used to measure mental fatigue. While thirty subjects perform the experiment, responses to the questionnaire and speech data were collected. Speech features related to speech source and the vocal tract filter were extracted from the speech data. According to the results, speech parameters deeply related to mental fatigue are a mean and standard deviation of fundamental frequency, jitter, and shimmer. This study shows that speech technology is a useful method for measuring mental fatigue.

• BMB Reports
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• v.29 no.2
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• pp.122-126
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• 1996

A series of oligonucleotides were synthesized by automatic DNA synthesizer. The purity of crude products was checked and their molecular weights determined by matrix assisted laser desorption ionization mass spectrometry (MALDI-MS) with an accuracy of better than 0.05% deviation even without using an internal standard. This mass determining technology in combination with partial digestion of oligonucleotides by 5'- and 3'-exonuclease provides a straightforward and simple method to obtain sequence information of oligonucleotides. The extension of this technology to the sequencing of modified oligonucleotides and genomic DNA and RNA might become possible.

• 한국전산유체공학회:학술대회논문집
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• 2005.10a
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• pp.45-47
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• 2005

We have investigated the mixing behavior of a tubular heat exchanger reactor using CFD and compared its mixing performance with different type of reactors such as jet mixer and continuous stirred tank reactor (CSTR). The mixedness in each reactor was quantified introducing a statistical average value, the coefficient of variation (CoV), which is a normalized standard deviation of concentration of a component over the whole fluid domain. Through the analysis of the flow pattern and turbulent energy distribution, we suggested a simple but effective way to improve the mixing performance of the tubular heat-exchanger reactor, which include the addition of the internals and/or the increase of the recycle flow rate. It was found that the CoV value of the tubular reactor could be nearly equivalent to that of CSTR by applying those two alternatives suggested here.

• Journal of Mechanical Science and Technology
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• v.18 no.4
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• pp.681-688
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• 2004

For use of the thermal cycle of the biochemical fluid sample, the isothermal temperature source with a large surface area was designed, fabricated and its thermal characterization was experimentally evaluated. The comprehensive overview of the technology trend on the temperature control devices was detailed. The large surface area isothermal temperature source was realized by using the vapor chamber heat spreader. The cost-effectiveness and simple manufacturing process were achieved by using the metal-etched wick structure. The temperature distribution was quantitatively investigated by using IR temperature imaging system at equivalent temperatures to the PCR thermal cycle. The standard deviation was measured to be within 0.7$^{\circ}C$ for each temperature cycle. This concludes that the presented isothermal temperature source enables no temperature gradient inside bio-sample fluid. Furthermore it can be applied to the cooling of the electronic devices due to its slimness and low thermal spreading resistance.

• Proceedings of the KIEE Conference
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• 2005.07a
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• pp.834-836
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• 2005

This paper describes algorithms for enhancing the reliability of measurements to verify the performance of energy efficiency programs with an simple method. Fundamentally, measurements contain erroneous data because of the various causes. and so proper procedures or schemes are prepared before the performance is evaluated. In this paper, we propose an approach for detecting and correcting an adulterate data, such as missing and bad data. Erroneous data are detected or corrected by pre-described measuring conditions, ensemble average, and standard deviation of measurements at measuring time. The proposed algorithms are tested by field test measurements. From case studies we drew the promising results.

• Proceedings of the Korea Water Resources Association Conference
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• 2003.05a
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• pp.151-158
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• 2003

Recently, there has been considerable interest in the influence of El Nino/Southern Oscillation (ENSO) on a global scale. ENSO has been measured by a simple index called Southern Oscillation Index (SOI). The statistical characteristics of SOI have been also focused to reveal the influence of ENSO. The SOI trend shows that El Nino events are generally getting stronger and more frequently occurring than La Nina events. However, the variation of SOI has varied significantly in a long-term. The SOI values are computed using the mean value and its standard deviation of the base period from 1951 to 1980. In the present study, the different base periods are applied to compute the SOI values and the influence of the different base periods is investigated in detail to reveal the long-term variation of SOI From the results, we could conclude that the present SOI should be carefully considered as a criterion to judge whether the El Nino and La Nina events are occurring.

• YAKHAK HOEJI
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• v.32 no.4
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• pp.251-257
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• 1988

A simple and sensitive HPLC method was developed for the simultaneous determination of ten kinds of active ingredients formulated in commercial cough-cold mixtures. A group of Pseudoephedrine HCl, dl-Methylephedrine HCl, Noscapine, Chlorophenylamine maleate, Dextromethorphan HBr and Phenylpropanolamine HCl were determined at 254nm using a Novapak $C_{18}$ column with mobile phase consisting of a mixture of methanol-acetonitrile-1, 4dioxane-tetrahydrofuran-water(12 : 20 : 20 : 5 : 43, pH4.7) containing 0.013M-dioctyl sodium sulfosuccinate. The another group of Acetoaminophen, Caffeine, Guaifenesin and Ethenzamide were also determined at 254nm using a Novapak $C_{18}$ column as the stationary phase, and a mixture of methanol-1% aqueous acetic acid (3 : 7). The results indicate that these methods are accurate and precise with relative standard deviation of not more than 1% (n=5) for the above active ingredients.

• Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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• v.10 no.S_1
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• pp.11-22
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• 2001

Observations related to the along-wind dispersion of puffs were collected from 12 field sites and from a wind tunnel experiment and used to test simple similarity relations. Because most of the date made use of concentration time series observation from fixed monitors, the basic observation was t, the standard deviation of the concentration time series. This data also allowed the travel time, t, from the source to the receptor to be estimated, from which the puff advective speed ue, could be determined. The along-wind dispersion coefficient, x, was then assumed to equal tue. The data, which extended over four orders of magnitude, supported the similarity relations t=0.1 t and x=1.8 $u^*$t, where t is the travel time and $u^*$ is the friction velocity. About 50% of the observations were within a factor of two of the predictions based on the similarity relations.