• 복식
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• 제61권1호
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• pp.47-57
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• 2011

This study is aimed at presenting the information on tailor-made clothes products which could positively relieve the psychological anxiety of the aged and enhance their living independence, and also at the development of clothes designs which could help them enjoy their healthy and activities. Based on the survey, the study conducted the research and analysis on the wearing practices, problems, and improvements for the clothes for the aged and found out their favorite clothes designs and colors. Based on the findings, the clothes models were recruited that reflect the physical features of silver-generation women and assist them with their joint protection. Moreover, the emphases were placed on the convenience of dressing or undressing, and the current fashion of development of clothes. The number of the clothes models developed were 11 for one pants suit, two skirt suits, one knit wear, one training wear, and one bolero.

• Archives of Plastic Surgery
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• 제34권2호
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• pp.169-175
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• 2007

Purpose: $Allevyn^{(R)}$(Smith & Nephew, England) is a type of polyurethane foam material with good wound discharge absorption. $Acticoat^{(R)}$(Smith & Nephew, England) is a silver coated dressing material which is effective in infected wound. The purpose of this study is to compare the effects of dry gauze, $Acticoat^{(R)}$ and $Allevyn^{(R)}$ on infected full-thickness wound healing in rat. Methods: One hundred and twenty rats were divided into 3 groups: group I(dressing with dry gauze, n=40), group II(dressing with $Allevyn^{(R)}$, n=40), group III(dressing with $Acticoat^{(R)}$, n=40). A $15{\times}15mm$ square full-thickness wound was made on the dorsum and left open for 24 hours. The size of wound defects were measured each dressing changes. The histological evaluation was performed on the 3rd day, 7th day, 14th day, 21th day. Results: After the wound was left open for 24 hours, typical findings of bacterial infection was observed. After the 7th day, group III showed larger area of epithelialization, smaller defect size compared to those of two other groups. Complete replacement by fibrotic scar tissue was observed in group III with no signs of inflammation on the 14th day. By day 21, the average defect size in group III was decreased from initial 100% to 3.63%. while in group I and II, it was decreased to 62.66% and 53.62%, respectively. Conclusion: $Acticoat^{(R)}$ is an effective tool in the treatment of infected wound.

• Archives of Plastic Surgery
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• 제38권4호
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• pp.359-368
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• 2011

Purpose: Aquacel Ag$^{(R)}$ is a hydrofiber wound dressing integrated with ionic silver. Sorbact$^{(R)}$ is a hydrophobiccoated dressing that uses the hydrophobic interaction with microbes. In this study, we compared the wound healing effects and the antibacterial effects of Medifoam$^{(R)}$, Betadine soaked, Aquacel Ag$^{(R)}$ and Sorbact$^{(R)}$ dressings against MRSA-infected wounds. Methods: Eighty rats were divided into four groups: Medifoam$^{(R)}$; Betadine soaked; Aquacel Ag$^{(R)}$; and Sorbact$^{(R)}$. A $1.5{\times}1.5cm$ square full-thickness wound was made on the dorsum of each rat and infected with MRSA. Twenty-four hours thereafter, each dressing was applied to the wound and changed every other day. One, 3, 7, 11 and 15 days after the wound infection, swab culture grade, wound bed appearance score, and wound defect size change were evaluated, and 7 and 15 days after, histologic evaluation was compared between the groups. Results: The bacteria load of wounds in the Sorbact$^{(R)}$ group decreased earlier than in the other groups. The wound bed appearance score of the Sorbact$^{(R)}$ group also increased quicker, compared with the other groups. However, the size of wounds of the Aquacel Ag$^{(R)}$ group decreased more rapidly, compared with other groups. From the histologic point of view, there was no significant difference between Betadine soaked, Aquacel Ag$^{(R)}$ and Sorbact groups. Conclusion: The hydrophobic dressing using Sorbact$^{(R)}$ showed a more rapid reduction in the MRSA load and an elevation in the wound bed appearance score, but a slower decrease in wound size change due to detachment of wound bed tissue when the dressing was eliminated in the low exudate wound. The silver-containing hydrofiber dressing using Aquacel Ag$^{(R)}$ was more effective in ultimate wound size reduction, but some debris was trapped in the wound tissue and induced foreign body reaction in the high exudate wound. Thus, ongoing selection process of treatment based on the evaluation of the infectious wound state will be very important.

• Archives of Plastic Surgery
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• 제36권4호
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• pp.372-379
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• 2009

Purpose: The purpose of this study was to compare the effect on antibacterial activities and wound healing effect of silver containing dressings with which of Betadine against Staphylococcus aureus and Pseudomonas aeruginosa. Methods: One full thickness skin defects in rats(n=72) were developed on the back and were given rise to infection with S. aureus(n=36) and P. aeruginosa(n=36). The 72 mice were divided into 6 groups : Acticoat$^{(R)}$, Aquacel$^{(R)}$-Ag, Medifoam silver$^{(R)}$, Polymen silver$^{(R)}$, Ilvadon$^{(R)}$ and Betadine(control group) dressing groups. Five silver containing dressings and Betadine were assesed on infected wound. Measurement of wound size change, bacterial colonies count and histologic findings was applied. Antibacterial activity was analyzed with bacterial restricted zone in Mueller Hinton agar. Results: On S. aureus, wound size was more decreased in all treated groups as compared with betadine, however Ilvadon$^{(R)}$ was less decreased on P. aeruginosa. In histologic findings, experimental group showed more effective findings than others on S. aureus, however on P. aeruginosa, which was showed similar. Acticoat$^{(R)}$ was best effective in wound healing against S. aureus and P. aeruginosa. The bacterial colonies count was increased in all treated groups except Acticoat$^{(R)}$ as compared with the control group on S. aureus, which was decreased in Acticoat$^{(R)}$ and Ilvadon$^{(R)}$ group on P. aeruginosa. There were not statistical differences. The restricted zone was shown in Mueller - Hinton agar of all groups except Medifoam silver$^{(R)}$ group on S. aureus, which was shown of all groups on P. aeruginosa. There were statistical differences. Conclusion: This study suggests that silver containing dressings may have not better potential than Betadine in assisting management of wounds at risk of infection on S. aureus and P. aeruginosa. However, which have better antibacterial activity on S. aureus and P. aeruginosa.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 추계학술대회
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• pp.327-330
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• 1996

Poly(L-leucine)(PLL)/poly(ethylene oxide)(PEO)/poly (L-leucine)(PLL) block copolymers were synthsized by polymerization of L-leucine N-carboxyanhydride with diamine-terminated PEO for possibility of wound dressing which may have several advantages such as 1) increase of solubility, 2) control of biodegradation, 3) absorption of body fluid. 4) non-immunogenic effect than PLL homopolymer wound dressing aleady commercialized. Water content increased with an increase of PEO content in the block copolymer due to the hydrophilicity of PEO. Release of silver sulfadiazine(AgSD) from AgSD loaded wound dressing increased with an increase of PEO content in the block copolymer. It was found that the number of Pseudomonas aeruginosa decrease with an increase of PEO content due to the fast release of antibacterial agents with an increase of PEO content in the block copolymer.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.249-254
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• 1997

ABA-type block copolymers composed of poly(L-leucine)(PLL) as the A component and poly(ethylene glycol)(PEG) as the B component were synthesized by ring-opening polymerization of L-leucine N-carboxyanhydride initiated by primary amino group located at both ends of PEG chain. A silver sulfadiazine(AgSD)-impregnated wound dressing of sponge-type was prepared by the lyophilization method. Morphological structure of this wound dressing obtained by scanning electron microscopy(SEM) was composed of a dense skin layer and a macroporous inner sponge layer. Equilibrium water content(EWC) of wound dressing was above 10%. It increased with an increased of PEO content in the block copolymer due to the hydrophilicity of PEO. AgSD release from AgSD- impregnated wound dressing in PBS buffer(pH=7.4) was dependent on PEG composition in the block copolymer. Therefore, EWC and release of AgSD can be control by PEG composition. Antibacterial capacity of AgSD-impregnated wound dressing was examined in agar plate against Pseudmonas aeruginosa and Stapplococus aruous. Cytotoxicity of the wound dressing was evaluated by studing mouse skin fibroblast(L929). From the behavior of antimicrobial releasing and the investigation of the suppression of bacterial proliferation, it was supposed that the wound dressing containing antibiotics could protect the wound surfaces from bacterial invasion to suppress the bacterial proliferation effectively. In cytotoxicity observation, cellular damage was reduced by the control led released of AgSD from the LEL sponge matrix of AgSD-medicated wound dressing. In vivo test, granulous tissue formation and wound contraction or the AgSD and DHEA impregnated wound dressing were aster than any other groups.

• 한국임상수의학회지
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• 제33권5호
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• pp.310-312
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• 2016

An 8-month-old, intact male Collie and a 4-year-old, intact male Siberian husky presented with severe wounds on the limbs. Although the wounds were not managed adequately before presentation, there were no remarkable findings except for secondary infections. The lesions were cleaned with a disinfectant and then treated with systemic antibiotics. Additionally, a hydrophilic moisture-absorbing polyurethane dressing was applied to the limbs because a conventional bandage with silver sulfadiazine ointment was not effective. Both cases showed significant improvement in the lesions over a short period of time. These cases show that a bioactive dressing works efficiently to heal refractory wounds in dogs.

• Journal of Korean Biological Nursing Science
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• 제5권1호
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• pp.23-33
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• 2003

본 연구는 체중 3.0kg의 가토 수컷 10마리를 이용하여 피부의 외상을 입힌 후 개방드레싱과 밀봉드레싱이 상처의 치유과정에서의 효과와 형태학적 차이를 비교하기 위해 1cm의 절개창과 $1.0{\times}0.2cm$의 피부절제창을 만든 후 개방드레싱군은 1일 2회 betadine으로 소독한 후 상처부위를 노출시켜 5, 10 및 15일째에 관찰하였으며, 밀봉드레싱군은 매일 betadine으로 소독하고 1% silver sulfadiazine 크림을 도포한 후 거즈를 덮어 5, 10 및 15일째에 광학현미경으로 관찰하여 다음과 같은 결론을 얻었다. 피부를 절개한 군과 절제한 군을 개방드레싱 및 밀봉드레싱을 각각 시행한 5일 후에는 딱지가 형성되었고 표피의 재생은 상처의 가장자리에서부터 시작하였다. 진피의 표층에는 호중구, 단구 및 림프구의 침윤이 일어났고 부종과 섬유아세포의 증식이 경하게 일어났다. 수상 후 개방드레싱 및 밀봉드레싱을 시행한 10일 후에는 딱지는 탈락되었고 표피는 재생되어 연속적이었다. 모세혈관의 수와 염증세포의 침윤은 감소하였다. 부종과 섬유아세포의 증식은 더욱 증가하였다. 수상 후 개방 및 밀봉드레싱을 시행한 후 15일에는 표피의 재생은 완성되어 각질이 형성되었다. 진피에는 염증세포의 침윤, 부종 및 혈관의 증식은 소실되었고 섬유아세포 및 교원섬유의 양은 증가하였다. 피부를 절개한 군은 절제 군에 비해 반흔의 양은 적었고 드레싱방법에따른 치유과정의 차이는 없었다. 이상의 성적으로 보아 상처의 치료는 드레싱의 방법보다 상처의 소독이 중요한 역할을 하는 것으로 사료된다.

• 보건의료산업학회지
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• 제6권2호
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• pp.71-80
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• 2012

The purposes of this study were to effect the upper extremities strength and ADL with upper extremities in frail elders. This study comparison upper extremities strength to pre-exercise and post-exercise and ADL with upper extremities. 30 elders who was in C silver hospital in Busan after resistance exercise during 12 weeks using elastic band, It was confirmed that improvement upper extremities strength and ADL with upper extremities after resistance exercise. As a result of study about effect of elastic band based resistance exercise on ADL of frail elders, it seems to have good effect on over all items(eating, dressing, bathing, make-up, go to a rest room). Therefore, it is necessary to find method about rehabilitation exercise for frail or partial disability elders.

• 통합자연과학논문집
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• 제12권2호
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• pp.47-57
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• 2019

Staphylococcus epidermidis is well-known not only as an innocuous normal flora species commonly isolated from human skin, but also as an important bacterial species to keep skin healthy, because this species can protect the human skin from pathogenic microorganisms. However, S. epidermidis turns into a potential pathogen in damaged skin, because these bacteria can easily form a biofilm on the wound area and provide antimicrobial resistance to other microorganisms embedded in the biofilm. Thus, it is important to kill S. epidermidis in the early stage of wound treatment and block the formation of biofilms in advance. In the present study, hydrogel wound dressings were fabricated using polyvinyl alcohol/polyethylene glycol containing silver citrate nanorods, which have been proven to have strong antimicrobial activity, especially against S. epidermidis, and their wound-healing efficacy was investigated in vivo using a rat experiment.