• Journal of the Korean Association of Geographic Information Studies
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• v.22 no.3
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• pp.10-20
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• 2019

Irregular rainfall caused by climate change, in combination with non-point pollution, can cause water systems worldwide to suffer from frequent eutrophication and algal blooms. This type of water pollution is more common in agricultural prone to water system inflow of non-point pollution. Therefore, in this study, the correlation between Unmanned Aerial Vehicle(UAV) multi-spectral images and total phosphorus, total nitrogen, and chlorophyll-a with indirect association of algal blooms, was analyzed to identify the usability of UAV image to identify water quality characteristics in agricultural streams. The analysis the vegetation index Normalized Differences Index (NDVI), the Normalized Differences Red Edge(NDRE), and the Chlorophyll Index Red Edge(CIRE) for the detection of multi-spectral images and algal blooms collected from the target regions Yang cheon and Hamyang Wicheon. The analysis of the correlation between image values and water quality analysis values for the water sampling points, total phosphorus at a significance level of 0.05 was correlated with the CIRE(0.66), and chlorophyll-a showed correlation with Blue(-0.67), Green(-0.66), NDVI(0.75), NDRE (0.67), CIRE(0.74). Total nitrogen was correlated with the Red(-0.64), Red edge (-0.64) and Near-Infrared Ray(NIR)(-0.72) wavelength at the significance level of 0.05. The results of this study confirmed a significant correlations between multi-spectral images collected through UAV and the factors responsible for water pollution, In the case of the vegetation index used for the detection of algal bloom, the possibility of identification of not only chlorophyll-a but also total phosphorus was confirmed. This data will be used as a meaningful data for counterplan such as selecting non-point pollution apprehensive area in agricultural area.

• Korean Journal of Psychosomatic Medicine
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• v.26 no.2
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• pp.188-193
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• 2018

Objectives : Clozapine is a widely prescribed antipsychotic drug for schizophrenia and is known to increase the risk of cardiovascular disease due to its metabolic side effects. However, little is known about the effect of clozapine on the platelet activation, another important factor in the development of cardiovascular disease. In this study, we tried to investigate the effect of clozapine on platelet activity in patients with schizophrenia by comparing the mean platelet component (MPC) values before and after the clozapine administration. Methods : A retrospective review of medical records of patients with schizophrenia, who newly started clozapine treatment from September 1st, 2003 to April 30th, 2007 at the Department of Psychiatry, Konyang University Hospital in Republic of Korea was performed. The final statistical analysis included 14 participants. Bayer ADVIA $120^{(R)}$ system was used to measure MPC. Results : Among the 14 participants, five subjects were males (28.60%), and ten subjects were females (71.40%). The mean age of participants was $37.50{\pm}11.64years$. Average of duration of illness was $91.00{\pm}93.96months$, with the mean dosage of clozapine taken by participants at the time of the last blood test was $337.50{\pm}109.52mg$. The mean MPC measurement before and after receiving clozapine was $26.12{\pm}2.22g/dL$ and $25.14{\pm}2.08g/dL$ respectively. Wilcoxon signed rank test showed that there was a statistically significant decrease in MPC levels after clozapine administration (V=16, p=0.024). Conclusions : Decreased MPC levels after clozapine administration implies that clozapine may increase platelet activation which could have an adverse effect on the occurrence of thromboembolic disease. Our findings also suggest that careful monitoring of the risk factors of cardiovascular diseases, such as platelets activity, is necessary when administering clozapine.

• Journal of Climate Change Research
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• v.5 no.1
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• pp.71-81
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• 2014

Using the Eddy Covariance technique, we analyzed seasonal variation in net ecosystem $CO_2$ exchange (NEE) and investigated the effects of environmental factors and aboveground biomass of rice on the $CO_2$ fluxes in a rice-barley double cropping paddy field of Gimje, Korea. Quality control and gap-filling were conducted before this investigation of the effects. The results have been showed that NEE, gross primary production (GPP), and ecosystem respiration (Re) during the rice growing period were -215.6, 763.9, and $548.3g\;C\;m^{-2}$, respectively. Relation between NEE and net radiation (Rn) could be described by a quadratic equation, and about 65 % of variation in NEE was explained by changes in Rn. On the other hand, an exponential function relating Re to soil temperature accounted for approximately 43 % of variation in Re under the flooded condition of paddy field. Aboveground biomass showed significant linear relationships with NEE ($r^2=0.93$), GPP ($r^2=0.96$), and Re ($r^2=0.95$), respectively.

• Korean Journal of Poultry Science
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• v.46 no.1
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• pp.31-37
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• 2019

A chicken clathrin-associated adaptor protein $3-{\delta}$ subunit 2 (AP3S2) is a subunit of AP3, which is involved in cargo protein trafficking to target membrane with clathrin-coated vesicles. AP3S2 may play a role in virus entry into host cells through clathrin-dependent endocytosis. AP3S2 is also known to participate in metabolic disease developments of progressions, such as liver fibrosis with hepatitis C virus infection and type 2 diabetes mellitus. Chicken AP3S2 (chAP3S2) gene was originally identified as one of the differentially expressed genes (DEGs) in chicken kidney which was fed with different calcium doses. This study aims to characterize the molecular characteristics, gene expression patterns, and transcriptional regulation of chAP3S2 in response to the stimulation of Toll-like receptor 3 (TLR3) to understand the involvement of chAP3S2 in metabolic disease in chicken. As a result, the structure prediction of chAP3S2 gene revealed that the gene is highly conserved among AP3S2 orthologs from other species. Evolutionarily, it was suggested that chAP3S2 is relatively closely related to zebrafish, and fairly far from mammal AP3S2. The transcriptional profile revealed that chAP3S2 gene was highly expressed in chicken lung and spleen tissues, and under the stimulation of poly (I:C), the chAP3S2 expression was down-regulated in DF-1 cells (P<0.05). However, the presence of the transcriptional inhibitors, BAY 11-7085 (Bay) as an inhibitor for nuclear factor ${\kappa}B$ ($NF{\kappa}B$) or Tanshinone IIA (Tan-II) as an inhibitor for activated protein 1 (AP-1), did not affect the expressional level of chAP3S2, suggesting that these transcription factors might be dispensable for TLR3 mediated repression. These results suggest that chAP3S2 gene may play a significant role against viral infection and be involved in TLR3 signaling pathway. Further study about the transcriptional regulation of chAP3S2 in TLR3 pathways and the mechanism of chAP3S2 upon virus entry shall be needed.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.63 no.4
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• pp.294-303
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• 2018

To set an optimal harvest time for five main whole-crop silage (WCS) rice cultivars, Nokyang (Ny), Mogwoo (Mw), Mogyang (My), Nokwoo (Nw) and Yeongwoo(Yw), based on feed value and dry matter yield, we analyzed water content (WC), feed values such as percent crude protein (CP), crude fat (CF), crude ash (CA), neutral detergent fiber (NDF), acid detergent fiber (ADF), estimated total digestible nutrients (TDN), and calculated their dry matter yield (DMY). These parameters were estimated at the booting stage and every 10 days from start of heading to 45 days after heading (DAH) to identify the optimal harvest time for these rice varieties. In all varieties, except Ny, the WC was about 65% on the $30^{th}$ DAH. In terms of WC, it is judged that there would be no major problem in preparing high quality silage when harvested between 20~30 DAH for Ny and about 30 days for the other cultivars. The CP and CA decreased significantly as the harvest time was delayed in all varieties (p<0.05). However, the CF in the tested varieties generally declined as DAH increased, and then increased again(p<0.05). The decrease in ADF and NDF was significantly different from the booting stage to 45 DAH in all varieties (p<0.05) and the estimated TDN increased gradually in all varieties as the harvest time was delayed. The TDN of all varieties, except Nw, was over 70% around 30 DAH. As harvest time was delayed, the DMY for all WCS rice increased significantly (p<0.05). The maximum DMY for each cultivar was observed at 45 DAH, however, no significant difference (p<0.05) was seen after 40 DAH for Ny and Yw, 30 DAH for Mw and Nw, and 20 DAH for My. Considering these results and others factors such as lodging, shattering, digestibility of grains, conversion of eating rice, etc., the optimal harvest time for silage use of all WCS rice tested was generally the yellow ripening stage, at about 30 DAH (30~40 DAH for Ny and Mw, and 30 DAH for My, Nw and Yw).

• Korean Journal of Environmental Biology
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• v.37 no.1
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• pp.93-108
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• 2019

To investigate the temporal-spatial distribution of picophytoplankton in relation to different water masses in the northern East China Sea (ECS), picophytoplankton abundance were investigated using flow cytometry with environmental factors in 2016-2017. The results from the analysis of flow cytometer data showed that Synechococcus appeared across all seasons, exhibiting its minimum abundance in winter and maximum abundance in summer. Furthermore, high abundance was detected in the surface mixed layer during spring and summer when vertical stratification occurs; in particular, Synechococcus exhibited maximum abundance in thermocline layer, indicating a close correlation to water temperature and thermocline formation. In addition, the abundance of Synechococcus indicated a decrease in the western seas in 2017 compared to 2016 under the strong influence of the Changjiang Diluted Water (CDW). This was determined by the significant influence of the CDW on the abundance of Synechococcus during summer in the northern waters of the ECS. In contrast, Prochlorococcus did not appear during winter and spring, and its distribution was limited during summer and autumn in the eastern seas under the influence of the Kuroshio current. The largest range of Prochlorococcus distribution was confirmed during autumn without the influence of the CDW. Thus, the distribution pattern of each picophytoplankton genus was found to be changing in accordance to the extension and reduction of sea current in different seasons and periods of time. This is anticipated to be a useful biological marker in understanding the distribution of sea currents and their influence in the northern waters of the ECS.

• Journal of the Korean Society of Radiology
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• v.13 no.3
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• pp.339-348
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• 2019

The purpose of this study was to investigate the effect of carotid artery ultrasound Respectively. The carotid intima-media thickness is known to have a significant correlation with cardiovascular disease and cerebrovascular disease. We investigated the relationship between carotid intima - media thickness, body mass index, waist circumference, the blood lipid value, fasting blood glucose, glycated hemoglobin, and blood pressure using carotid artery ultrasound. The carotid artery ultrasound was considered to be abnormality of IMT thickness over 0.8 mm and the presence or absence of atherosclerotic plaque was evaluated. Serological tests were used to compare the geologic value, fasting blood glucose level, and glycated hemoglobin. As a result, waist circumference (=.022), low density cholesterol (=.004), fasting blood glucose level (.019), and glycemic index (.002) were analyzed as predictors of atherosclerosis. In the ROC curve analysis, sensitivity was 87.80% (95% CI: 73.8-95.9), specificity was 41.67% (95% CI: 30.2-53.9), sensitivity was 78.05% (95% CI: 62.4-89.4) in low density lipoprotein, Specificity was 50.00% (95% CI: 38.0-62.0), sensitivity was 73.11% (95% CI: 57.1-85.8), specificity was 61.11 (95% CI: 48.9-72.4) and sensitivity was 82.93%-91.8) and a specificity of 43.06% (31.4-55.3). In logistic regression analysis, the risk of atherosclerosis was 0.248 times at waist circumference (WC)> 76 cm, 3.475 times at low-density lipoprotein (LDL-C) ${\geq}124mg/dL$, 0.618 at HbA1c> 5.4% It appeared as a times. We suggest that prospective study of carotid artery ultrasound should be performed for the effective prevention of cardiovascular diseases.

• Journal of the Korean Applied Science and Technology
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• v.36 no.3
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• pp.942-953
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• 2019

The objective of this study was to evaluate the effects of L-arginine supplementation on muscle damage and fatigue indices and athletic performance improvement of canoe athletes after conducting a high-intensity training program. To achieve the objective, this study applied a high-intensity training program to seven high school canoe athletes. The high-intensity training program is composed of aerobic exercise sessions (twice per week; Tuesday and Thursday), anaerobic exercise sessions (three times per week; Monday, Wednesday, and Friday), and flexibility exercise sessions (five times per week). During the 6 week high-intensity training program, drug ingestion (L-arginine or placebo) was conducted in the first two weeks, wash out (two weeks) followed it, and drug ingestion (L-arginine or placebo) was carried out again in the last two weeks. The crossover design was used for the experiment so all study subjects were assigned to either the L-arginine intake group (the treatment group) or the placebo group (the control group). Each subject ingested 3g per day. This study confirmed the significant effects of L-arginine supplementation on muscle damage indices, fatigue indices, and antioxidants using blood samples. Additionally, FMD was analyzed to evaluate vascular endothelial cell functions and canoe performance was examined using the canoe ergometer. The results of this study showed that L-arginine intake did not have direct effects on the levels of ammonia, IP, and CK. The level of LDH decreased significantly more in the ARG group than in the PLA group due to L-arginine supplementation. Moreover, L-arginine supplementation did not change total NO, d-ROMs, BAP, and FMD significantly. Lastly, the results of the 500m canoe ergometer, which was conducted to evaluate the canoe performance, revealed that L-arginine did not have direct effects on total time, stroke distance, and mean velocity. However, L-arginine supplementation significantly improved muscle damage indices, fatigue indices, antioxidants, FMD, and canoe performance. Therefore, it is believed that additional studies are needed for examining the potential effects of L-arginine supplementation athletic performance enhancement.

• Korean Journal of Environment and Ecology
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• v.33 no.4
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• pp.378-401
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• 2019

This study generated a list of plants in eight sections from the Baekdansa ticket office (874m) to Cheonjedan (1,560m) divided in the interval of 100m above sea level to examine the species diversity patterns and distribution changes of the vascular plants at different altitudes in Taebaeksan National Park. Four site surveys found a total of 385 taxa: 89 families, 240 genera, 345 species, 5 subspecies, 34 varieties, and 1 form. A result of analyzing the change of species diversity along elevational gradients showed that it decreased with increasing elevation and then increased from a certain section. A result of analyzing habitat affinity types showed that the proportion of forest species increased with increasing elevation. On the other hand, the ruderal species appeared at a high rate in the artificial interference section. A result of comparing the proportion of woody and herb plants showed that the woody plants gradually increased with elevation and rapidly decreased in the artificial interference section. On the other hand, the herb plants showed the opposite trend. A result of analyzing the change of distribution of species according to altitude with the DCA technique showed that the vascular plants were divided into three groups according to the elevation in order on the I axis with the boundaries at 900m and 1,300m above sea level. The arrangement of each stand from right to left along the altitude on the I axis with a significant correlation with warmth index (WI) confirmed that the temperature change along the altitude could affect the distribution of vascular plants, composition, and diversity. Therefore, the continuous monitoring is necessary to confirm ecological and environmental characteristics of vegetation, distribution ranges, changes of habitat. We expect that the results of this study will be used as the basic data for establishing the measurement measures related to the preservation of biodiversity and climate change.

• Korean Journal of Environment and Ecology
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• v.33 no.4
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• pp.472-480
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• 2019

Selection of the plant material for planting to reduce fine dust should comprehensively consider the visual characteristics, such as the shape and texture of the plant leaves and form of bark, which affect the adsorption function of the plant. However, previous studies on reduction of fine dust through plants have focused on the absorption function rather than the adsorption function of plants and on foliage plants, which are indoor plants, rather than the outdoor plants. In particular, the criterion for selection of fine dust reduction species is not specific, so research on the selection criteria for plant materials for fine dust reduction in urban areas is needed. The purpose of this study is to identify the priorities of eight indicators that affect the fine dust reduction by using the fuzzy multi-criteria decision-making model (MCDM) and establish the tree selection criteria for the urban planting to reduce fine dust. For the purpose, we conducted a questionnaire survey of those who majored in fine dust-related academic fields and those with experience of researching fine dust. A result of the survey showed that the area of leaf and the tree species received the highest score as the factors that affect the fine dust reduction. They were followed by the surface roughness of leaves, tree height, growth rate, complexity of leaves, edge shape of leaves, and bark feature in that order. When selecting the species that have leaves with the coarse surface, it is better to select the trees with wooly, glossy, and waxy layers on the leaves. When considering the shape of the leaves, it is better to select the two-type or three-type leaves and palm-shaped leaves than the single-type leaves and to select the serrated leaves than the smooth edged leaves to increase the surface area for adsorbing fine dust in the air on the surface of the leaves. When considering the characteristics of the bark, it is better to select trees that have cork layers or show or are likely to show the bark loosening or cracks than to select those with lenticel or patterned barks. This study is significant in that it presents the priorities of the selection criteria of plant material based on the visual characteristics that affect the adsorption of fine dust for the planning of planting to reduce fine dust in the urban area. The results of this study can be used as basic data for the selection of trees for plantation planning in the urban area.