• Title/Summary/Keyword: Significance Level

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Multilevel Analysis on the Risk Factors for Depression in Jeollabuk-do (우울증 위험요인에 관한 다수준 분석: 전라북도 주민을 대상으로)

  • Jungwoo, Sohn
    • Journal of agricultural medicine and community health
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    • v.47 no.4
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    • pp.268-274
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    • 2022
  • Objectives: The purpose of this study was to identify the individual and regional risk factors on depression using community-based data in Jeollabuk-do. Methods: This cross-sectional study obtained data from the Community Health Survey 2018 in Jeollabuk-do. The dependent variable was depression measured by Patient Health Questionnaire-9 (PHQ-9). The prevalence of depression was defined if total score of PHQ-9 was 10 or higher. A multilevel analysis was conducted to consider individual and regional level independent variables that could be risk factors for depression. Results: In the individual level, female gender and smokers had significantly higher odds ratios (ORs) for depression of 1.58 and 1.72, respectively. Subjects with economic activity, higher income and higher education had significantly lower ORs of 0.53, 0.41 and 0.66. In the regional level, higher greening rates and lower levels of PM2.5 had statistically lower ORs at the significance level of 10%. Conclusion: By conducting this study, risk factors associated with depression were identified in individual- and regional-level. This study suggests that health projects are needed to control regional level risk factors including community networks for mental health management in addition to the traditional individual level risk factors.

Prognostic Significance of Circulating Tumor Cells and Serum CA15-3 Levels in Metastatic Breast Cancer, Single Center Experience, Preliminary Results

  • Tarhan, Mustafa Oktay;Gonel, Ataman;Kucukzeybek, Yuksel;Erten, Cigdem;Cuhadar, Serap;Yigit, Seyran Ceri;Atay, Aysenur;Somali, Isil;Dirican, Ahmet;Demir, Lutfiye;Koseoglu, Mehmet
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.3
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    • pp.1725-1729
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    • 2013
  • Background: Breast cancer is the second leading cancer causing death in women. Circulating tumor cells are among the prognostic factors while tumor markers are of diagnostic value and can be used for follow-up. The aim of this study was to investigate the correlation between the prognostic significance of the serum CA15-3 levels, number of circulating tumor cells and histopathological tumor factors. Materials and Methods: Thirty patients recently diagnosed with breast cancer were included in the study. Number of circulating tumor cells and serum CA15-3 level were assessed when metastasis was detected and diagnostic value was assessed. Presence of associations with estrogen and progesterone receptors, c-erbB2, Ki-67 proliferation index and histological grade were also evaluated. Results: Median overall survival of the patients with serum CA15-3 levels of >108 ng/dl was 19 months whereas for those with a low serum level it was 62 months. Median overall survival for CTC ${\geq}5$ vs CTC<5 patients was 19 months and 40 months respectively. The difference between the two groups was statistically significant. Conclusions: Prognostic significance of the CTC count and CA15-3 levels in metastatic breast cancer patients was demonstrated.

The Effects of Site Environmental Factors on Estimation of Site Index Function for Chamaecyparis obtusa Endlicher Stands (입지환경인자를 바탕으로 한 편백의 지위지수 추정에 관한 연구)

  • Kim, Dae-Hyun;Kim, Eui-Gyeong;Lee, Sung-Gi;Chung, Young-Gyo;Jeong, Jin-Hyun
    • Journal of Environmental Science International
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    • v.17 no.8
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    • pp.891-898
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    • 2008
  • This study was conducted to develop the effects of site environmental factors on estimation of site index function for Chamaecyparis obtusa Endlicher stands. We derived nonlinear growth equation and the draw site index curves by applying this estimated equation. This study with Chapman-Richards function showed significant P-value which was less then 0.0001 and $R^2$ value 0.5947. This study was conducted to develop the feasible site index equation of Chamaecyparis obtusa Endlicher. For the table, the data of 82 sample areas that were thought to be without errors among the data of Chamaecyparis obtusa Endlicher sample area located on the value-oriented forest location chart were used and estimated. After analyzing the quantification method I based on 13 environmental factors to develop the score table for the site-index estimation of Chamaecyparis obtusa Endlicher, $R^2$ value of the model was 0.7555. It has been analyzed that the scope value of Soil moisture in horizon A was 7.5045, that of total soil depth was 6.3896, that of topography was 5.3471, that of slope was 4.7000 and that of aspect was 3.2038. After analyzing the partial correlation to examine the factors that affected most the site-index of Chamaecyparis obtusa Endlicher, it has been noted that the partial correlation of climatic zone was 0.4987, which was highest, and it was followed by Soil moisture in horizon A (0.4592), slope (0.4537), topography (0.3299) and total soil depth (0.1035). As a result of conducting the significance test for partial correlation, it has been found that topography, climatic zone, parent rock, slope, altitude, aspect, Soil moisture in horizon A, soil hardness in horizon A and total soil depth were recognized significant with 1% of significance level and sedimentary type and soil texture in horizon A were recognized significant with 5% of significance level.

Antitumor Effect of Hang-Am-Dan Non-boiled Water Extracts on NCI-H460 Tumor Regression Model

  • Kim, Jun-Lae;Kim, Kyung-Soon;Park, Jae-Woo;Lee, Yeon-Weol;Cho, Chong-Kwan;Yoo, Hwa-Seung
    • The Journal of Korean Medicine
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    • v.31 no.3
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    • pp.34-46
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    • 2010
  • Objective: This experimental study was performed to examine if Hang-Am-Dan non-boiled water extracts (HAD-N) induce apoptosis in human lung carcinoma NCI-H460 cells in vitro and inhibits the growth of NCI-H460 cell-transplanted solid tumor in vivo. Materials and Methods: We cultured NCI-H460 cell lines and xenografted them to nude mice. The mice were divided into 3 groups, NCI-H460 cell alone, NCI-H460 + 90 mg/kg HAD-N treated group, and NCI-H460 + 180 mg/kg HAD-N treated group, with seven mice per group. HAD-N was orally administrated every day for four weeks. We checked their body weight and tumor weight and volumes two times a week and their absolute organ weight and biochemical blood analysis at the final day by sacrificing them. We also calculated their tumor inhibition rate (IR), mean survival time and percent increase in life span (% ILS). Results: In this study, we observed that all of the HAD-N treated mice got smaller tumors. The more doses of HAD-N used, the less IR showed at the 8th day after starting this experiment. Tumor weight and volume of HAD-N treatment groups also decreased. Mean survival time and percent increase in life span (% ILS) in the high-dose HAD-N treatment groups were higher than those of other groups. The test substances in the blood level UN results showed reduction in the significance in both HAD-N 90 mg/kg and HAD-N 180 mg/kg (p<0.01). The blood level phosphatase results in HAD-N 90 mg/kg group compared to NCI-H460 cell alone group showed a reduction in significance (p<0.05). AST levels HAD-N 180 mg/kg group compared to NCI-H460 cell alone group significance as well (p<0.05). Conclusion: We suggest that the results of the in vivo study showed that HAD-N may have potential as a growth inhibitor of tumor-induced NCI-H460 of nude mice in spite of the shortcomings of this study. More studies to overcome those shortcomings and to find out significant antitumor mechanism will be needed.

Safety of Bojungikgi-tang Soft Extract after Single Oral Administration in Healthy Male Volunteers, Single Center Study (보중익기탕연조엑스의 1회 경구투여 후 안전성 평가에 관한 단일기관 연구)

  • An, Sung-Hu;Jeong, Yeong-jin;Kim, Jong-gyu;Shin, Hyeryung;Kwon, Young-Dal
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.4
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    • pp.157-166
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    • 2021
  • Objectives This study is designed to evaluate the safety of Bojungikgi-tang soft extract in healthy male volunteers. Methods 12 healthy male volunteers were recruited and this study was carried out by a single center. Laboratory test results, vital signs of the volunteers were collected to evaluate safety. According to registration order, the 12 subjects were allocated by serial number. To evaluate safety, blood samples were taken and vital signs were checked 4 times - screening, pre administration, post administration and follow up-during the whole trial. The difference between pre (before medication [0 hr]) and post-administration (after medication [48 hr]) variables was summarized as mean±standard deviation. The normality test was performed using the Kolmogorov-Smirnov test and Shapiro-Wilk test. When the normality is satisfied, the paired t-test is applied. Otherwise, the non-parametric method, Wilcoxon signed rank test is applied. The significance level was p<0.05. The incidence of all adverse effects are shown in percentage. Results In the case of red blood cell, hemoglobin, hematocrit, lymphocytes, neutrophils, protein, γ-glutamyl transpeptidase values, the normality test result of the variable for the difference value before and after the dosing has a significance level <0.05. But most of values did not deviate from the normal range, and the deviation from the normal range could not be regarded as the significance associated with this clinical trial. And adverse event wasn't observed associated with the clinical trial drug. Conclusions Bojungikgi-tang soft extract were considered to be safe for healthy male volunteers.

Study on Hospital Environmental Causes Affected the Mother′s Comfort After Her Child Birth (산욕부 안위에 영향을 미치는 병원환경 요인에 관한 연구)

  • 변수자
    • Journal of Korean Academy of Nursing
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    • v.8 no.1
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    • pp.1-15
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    • 1978
  • The Purpose of this study is to examine closely the causes influenced upon the comfort and recovery of the woman delivered of a child in the hospital at the same time to understand environmental status of hospitals in order to promote mother's health recovery, and to improve hospital environment by emphasizing the meaning of environment and health before the medical staff and hospital administrative authority. In the method of servery of the research, 165 post paestum patients have been randomly selected who were accommodated and delivered their babies at OB(obstetric ) & GY (Gynecologic) unit the 7 general hospitals for the period of 6 December 1976 through 17 December 1976. As for the survey, it has been used of Questionnaire where we have 65 items in the respect of personal environment in the hospital such as trusting nurse, ability, reliability, kindness and etiquette of nurse and tile character of nurse the relationship with patients the other respect of physical environment included 9f temperature, moisture. air-ventilation lightening noise, cleanness. facilities, and the third realm being of mother's hearth ground to have the following conclusion 1. The feature of the collected personnel they are from OB or GY sects of from OB unit of the other 5 hospitals except the two general hospitals of the college or school Otherwise the rate of the patients to nurses would be 9 : 1. As for the nurses'ground it would be appeared of 20-25 years of age as the 76%. either 3 year course or 4 year course in the education would be each 50% and less than 2 year experience case would record as of 60 %. In the respect of hospital physical environmental status, there we have two hospitals without any thermometers, on the other han4 nowhere there's hygrometer, otherwise, the lightening is normal or over than normal As for the structure of noise protection the corridors're, generally speaking worse than rooms, nerver hueless, there's no ventilating system in the hospitals. The rooms'repainted in white and yellow, light green white, or green color. The patient's clothing were in green pink blue, light green or in white co for. There're not anything special in both decoration and equipments. Most of them used tall beds except in one hospital 2. To the extent of perception of patient's hatch 9round and hospital environment it is presented that they perceived nurse's ability in highest in total human variable, though perceived kindness or etiquette in the lowest otherwise, comparatively high in total average. 3. In the respect of physical environment it is highest perceived of lightening terms, otherwise, lowest perceived of air ventilation and total average became lowest than the one of the original record 4. To ages, in the respect of hatch ground rather old aged mother than the younger one has perceived that nurse would be trusting, in good service character, able, at the same time, liable, Otherwise, in physical environment regardless of age, they perceived lightening in high and remarkably lower in ventilation As a result of the examination of the difference in hospital environment to each age it is appeared of statistical difference at 5% level of ability in the personal environment otherwise little difference as for physical environment 5. In the respect of perceiving level to educational standard it is highly perceived of personal environment for higher ranking group rather than lower group in the educational standard. In case of physical environment it is highly perceived for lower level group rather than higher level group in educational background. The variables which have statistical significance at 5% level are from trusting kindness, etiquette and total kindness, etiquette and total all significance at 5% level are from trusting, kindness, etiquette and total human environment variable in personal environment, otherwise, there's little difference in the physical environment. 6. The perceiving level due to times of admission and accommodation at the hospital would be cleared out as gradual higher perception both physical and personal environment in the hospital. At 5% significant level of the ventilation condition in physical environmental variable it is presented of meaningful difference otherwise, there we have little difference both in Personal variable and other one. 7. In accordance with living standard, the perception degree of personal environment in tee hospital would be inclined to increase to higher living standard on the other hand, in case of the physical environment, the perception level world increase to lower living standard At 5 % level, the trustuariable and total scores in the personal eicuironmectal variable there appeared a meaningful/ significant difference otherwise, there presented little difference both in physical environmental and other variable to the living standard 8. Pertaining to family unit, the mother of an independent family unit perceived highly in all respect of the personal and the physical environment in the hospital rather than the woman of succeeding family unit. At 5 % level there appeared a difference in the respect of kindness and etiquette both in personal environment variable, on the other hand, there hardly marked a difference between other variable and physical environmental one. 9. The degree of perception to comforting level has little connection with a statistical difference the age, educational level hospital admitting times, living standard or family unit. 10. The most effective variable to mother's comforting level will be nurse's ability, reliability, trusting manner, and total physical environment variable in order.

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The Factors Affecting Health Promoting Lifestyle in Patients with Pulmonary Tuberculosis (폐결핵 환자의 건강증진 생활양식과 그 영향 요인)

  • Chon, Mi-Young;Ryu, Eunjung
    • Korean Journal of Adult Nursing
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    • v.16 no.4
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    • pp.575-584
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    • 2004
  • Purpose: To describe the performance in the health-promoting lifestyle and to identify the major factors affecting the health-promoting relationships between self care behaviors and health promoting lifestyle profile in patients with pulmonary tuberculosis. Method: A convenience sample for this study was 172 pulmonary tuberculosis patients who have taken TB medications in urban city. The HPLP-II was selected to measure the concept of health-promoting lifestyle because of the number of research studies conducted using both the original HPLP and the revised HPLP-II. The statistical methods used in this study were t-test, ANOVA, Pearson correlations, and multiple regression. Result: The differences of the HPLP-II were found to have a significance of age, marital status, education level, and health service center. The level of self care behaviors was related positively to the level of health promoting lifestyle and their subcategories. Based on stepwise multiple regression analysis, the model that predicted factors included self care behaviors, age, health service center and education. Conclusion: After decades of decreasing rates, TB has reemerged as a serious national problem in Korea. The careful clinical management and more national concern of TB may help to improve the outcomes of many patients. The findings of this study suggest that TB patients who are more fulfilled in health-promoting lifestyles and self-care behaviors may be able to make better decisions regarding positive health-promoting behaviors.

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A Study on the Management of Engine Coolant in Small Fishing Vessels (소형선박 운용자의 냉각수 관리에 관한 고찰)

  • KIM, Young-Un
    • Journal of Fisheries and Marine Sciences Education
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    • v.27 no.6
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    • pp.1734-1744
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    • 2015
  • Majority of marine accidents that occur on fishing vessels are engine accidents. This comprises more than 26 % of the total annual fishing vessel marine accident cases. Large numbers of engine accidents happen in the cooling water system, which are mostly caused by negligence on regular check-up and repair. Notably, small-sized ships have higher engine accidents occurrence rate compared to medium-and large-sized ships. Based on the Report of the Korea Ship Safety Technology Authority, engine accident cases reached 3,032 out of the total 3,081 cases. This study researches on the differences between the small-sized ship pilot, an operator of a vessel engine of less than 200 tons, and a 6th level marine engineer, in terms of the relationship between management forms and what causes the marine accidents in association with the cooling water system. It also studies and analyzes the differences in frequency of the accident occurrence between the two groups. ${\chi}^2$ qualification was imposed through the SPSS statistical analysis program and it got qualified at the significance level of 5%. The research shall be utilized as one of the base line data for the reduction of marine accidents.

The Employees' Perception of the Effectiveness of Team System at University Hospitals in Korea (대학병원의 팀 운영특성에 따른 효과성 인식에 관한 연구)

  • 서영준;김연숙;강소영
    • Health Policy and Management
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    • v.11 no.3
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    • pp.1-30
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    • 2001
  • This study was conducted to evaluate the effectiveness of team system at university hospitals in Korea. Data were collected from administrative and medical support workers at 4 university hospitals through the self-administered questionnaires and analyzed using frequency analysis, t-test, and oneway ANOVA. The results of this study are as follows. First, teams with higher team management characteristics show higher level of quality of work life and performance effectiveness. Second, teams which consist of members with variety background and skills show higher level of quality of work life and performance effectiveness. Third, team which have the higher autonomy, technology variety, job significance, and feedback show higher team effectiveness. Fourth, team which have team leaders with higher leadership score show higher level of quality of work life and performance effectiveness. Fifth, there are differences in team effectiveness in terms of sicio- demographic variables such as average age, position, and tenure of team members, length of team system, and team size. Sixth, the job autonomy of team members and the leadership of team managers have significant effects on the quality of work life variables. Seventh, the leadership of team leaders, job autonomy of members, and individual contact between team managers and members have significant effects on the team performance variables. In conclusion, in order to increase the effectiveness of team system in university hospitals, it is required to consider the characteristics of team management, diversity of team members, the autonomy of team members, the leadership of team manager, and the socio-demographic factors of team members.

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Relationship between periodontal disease and level of high-sensitivity C reactive protein in Korean adults (한국 성인의 치주질환과 고감도 C-반응단백질 농도의 상관관계)

  • Son, So-Hyun;Lee, Eun-Sun
    • Journal of Korean society of Dental Hygiene
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    • v.19 no.6
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    • pp.919-929
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    • 2019
  • Objectives: The purpose of this study was to comprehensively examine the relationship between periodontal disease and high-sensitivity C reactive protein (hs-CRP) level. Methods: This study was conducted using the data from the sixth Korea National Health and Nutrition Examination Survey. SPSS 18.0 for Windows was used for statistical analysis. The data were collected from 4,576 subjects aged ≥19 years. To analyze the association between periodontal disease and hs-CRP level, chi-squared test and logistic regression analysis were used. Results: Consequent to correcting all the disturbance variables, the moderate risk of hs-CRP was 1.39 times higher in patients with periodontal disease than in those without (OR=1.39; 95% CI:1.14-1.69), whereas the high risk of hs-CRP was 1.10 times but there was no statistical significance (OR=1.10; 95% CI:0.79-1.53). Conclusions: Periodontal disease contributes to raising the risk of systemic inflammation and hs-CRP from low to moderate. Periodontal disease is associated with an early rise in hs-CRP.