• Korean Journal of Medicinal Crop Science
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• v.11 no.1
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• pp.31-39
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• 2003

The antioxidative activities and biological properties in the EtOAc extracts and purified extracts of Orostachys japonicus were measured by assay of DPPH, xanthine/xanthine oxidase and mammalian cells(2-12). Scavenging of DPPH radical and inhibition of xanthine/xanthine oxidase of EtOAc extracts were showed the highest activity in the arable land and in September. The S-4 fraction showed the highest activity among the silica-gel column chromatography fractions. LH-4 fraction showed higher activity than the other fractionsins in assay of DPPH and xanthine/xanthine oxidase. Fatty acids and phenolic compounds were identified by GC/MS and main compounds were 1,2,3-benzenetriol, alpha-androsta-7,14-diene in LH-4 fraction. The activities of POD and SOD in samples havested on different habitats were high such as arable land> intermountain> seashore. That of POD and SOD in crude extracts of late stage were higher than early stage. Isozyme bands of crude extracts samplinged in all habitats and all growing stages showed two bands and the signal intensity showed strongly according to passage of growing stage. The purified extracts of LH-4 fraction showed excellent inhibition effect in proliferation of HL-60 cells and markedly suppressed colony formation in mouse fibroblast cells. Dose response between partially purified extracts(400ppm) and negative control did not produced statistically significant reduction in colony formation.

• Journal of the Korean Geographical Society
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• v.42 no.6
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• pp.835-850
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• 2007

This study examines long-term trends of onset dates and durations of season decomposed by applying a lowpass filtering using observed 80-year(1921-2000) data and projected 2040s and 2090s data based on the IPCC SRES A1B emission scenario in South Korea. As recent climate changes on seasonal cycles in South Korea, the onset dates of spring and summer began earlier after 1970s. But onset dates of autumn and winter were delayed. Winter duration was more shortened during the post-1990 period. Summer duration is longer and winter duration is shorter at southern and eastern coastal area. The different of summer duration and winter duration in coastal area was longer than over the inland. The reduction in winter duration in South Korea agrees with results in overall global warming trends as a climate change signal. Future model output data predict that winter will disappear in Gangneung, Busan and Mokpo in the 2090s

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.7
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• pp.796-804
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• 2010

It is important to use the comb type pilot allocation for the continuous channel and efficient processing. And DFT-spreading OFDM is used a lot to solve high PAPR problem of OFDM system. However, PAPR is increased again when comb type pilot is used to estimate channel characteristics. So, in this paper, we employ a new SLM method to DFT-spreading OFDM system to reduce increased high PAPR. And we suggest an effective method to transmit side information without additional bandwidth. Pilot and side information must be preserved from jamming or intentional interferences since those are very important in DFT spread OFDM system using SLM. So, in this paper, we like to analyze and simulate the performance of DFT spread OFDM system based on SLM against jamming signal. To remedy the vulnerable shortcomings of DFT spread OFDM about jamming or intentional interferences, we employ FH(Frequency Hopping) method and analyze system performance under the several jamming conditions such as MTJ(Multi Tone Jamming) and PBJ(Partial Band Jamming).

• Journal of Broadcast Engineering
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• v.12 no.6
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• pp.596-610
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• 2007

In order to reduce the complexity of SVC encoding, we introduce a fast mode decision method in the enhancement layers of spatial scalability by selectively performing the inter-layer residual prediction of SVC. The Inter-layer residual prediction coding in Scalable Video Coding has a large advantage of enhancing the coding efficiency since it utilizes the correlation between two residuals from a lower spatial layer and its next higher spatial layer. However, this entails the dramatical increase in the complexity of SVC encoders. The proposed method is to analyze the characteristics of integer transform coefficients for the subtracted signal for two residuals from lower and upper spatial layers. Then it selectively performs the inter-layer residual prediction coding and rate-distortion optimizations in the upper spatial enhancement layer if the SAD values of residuals exceed adaptive threshold values. Therefore, by classifying the residuals according to the properties of integer-transform coefficients only with SAD of residuals between two layers, the SVC encoder can perform the inter-layer residual coding selectively, thus significantly reducing the total required encoding time. The proposed method results in reduction of the total encoding time with 51.5% in average while maintaining the RD performance with negligible amounts of quality degradation.

• Journal of Biomedical Engineering Research
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• v.19 no.2
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• pp.119-128
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• 1998

This paper describes a filtering algorithm which employs apriori information of SPECT lesion detectability potential for the filtering of degraded projection images prior to the backprojection reconstruction. In this algorithm, we determined m minimum detectable lesion sized(MDLSs) by assuming m object contrasts uniformly-chosen in the range of 0.0-1.0, based on a signal/noise model which provides the capability potential of SPECT in terms of physical factors. A best estimate of given projection image is attempted as a weighted combination of the subimages from m optimal filters whose design is focused on maximizing the local S/N ratios for the MDLS-lesions. These subimages show relatively larger resolution recovery effect and relatively smaller noise reduction effect with the decreased MDLS, and the weighting on each subimage was controlled by the difference between the subimage and the maximum-resolution-recovered projection image. The proposed filtering algoritym was tested on SPECT image reconstruction problems, and produced good results. Especially, this algorithm showed the adaptive effect that approximately averages the filter outputs in homogeneous areas and sensitively depends on each filter strength on contrast preserving/enhancing in textured lesion areas of the reconstructed image.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.7
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• pp.3169-3175
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• 2011

This paper describes the design of size-reduced directional coupler using the artificial dielectric substrate and its increased effective permittivity. Directional couplers are widely used in measuring RF power indirectly and coupling signal power. Artificial dielectric substrates have higher effective dielectric constant than standard dielectric substrate due to the lots of metalized via-holes, and the increased effective permittivity results in size-reduction of circuits. As a design example, 15dB directional couplers are designed on the standard substrate and artificial dielectric substrate and their size are compared. The size of the directional coupler using the artificial dielectric substrate is only 1/3 of that designed using the standard substrate, while the performances are preserved. In addition, the measured performances of the size-reduced coupler are well agreed with the simulated ones. The measured coupling coefficient, matching, and insertion loss at 2GHz are -14.62dB, -24.1dB, and -0.38dB, respectively.

• The KIPS Transactions:PartA
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• v.13A no.4 s.101
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• pp.275-288
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• 2006

Rapid design space exploration is crucial to customizing embedded system design for exploiting the application behavior. As the time-to-market becomes a key concern of the design, the approach based on an application specific instruction-set processor (ASIP) is considered more seriously as one alternative design methodology. In this approach, the instruction set architecture (ISA) for a target processor is frequently modified to best fit the application with regard to code size and speed. Two goals of this paper is to introduce our new retargetable compiler and how it has been used in ASIP-based design space exploration for a popular digital signal processing (DSP) application. Newly developed retargetable compiler provides not only the functionality of previous retargetable compilers but also visualizes the features of the application program and profiles it so that it can help architecture designers and application programmers to insert new application specific instructions into target architecture for performance increase. Given an initial RISC-style ISA for the target processor, we characterized the application code and incrementally updated the ISA with more application specific instructions to give the compiler a better chance to optimize assembly code for the application. We get 32% performance increase and 20% program size reduction using 6 audio codec specific instructions from retargetable compiler. Our experimental results manifest a glimpse of evidence that a higgly retargetable compiler is essential to rapidly prototype a new ASIP for a specific application.

• Korean Journal of Materials Research
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• v.9 no.12
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• pp.1245-1251
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• 1999

Phase-change optical disk very rapid recording, high densification of data, resulting in high feedback rate and good C/N(carrier to noise) ratio of a feedback signal. However, repetitive thermal energy may cause the deformation of a disk or the lowering of an eliminability and a cyclability of the recording. The lowering of the cyclability can be reduced by insertion of thin layer of ZnS-$SiO_2$ dielectric thin film in appropriate disk structure between the upper and lower part of the recording film. Using the Taguchi method, optimum conditions satisfying both the optimized quality characteristic values and the scattering values for film formation were found to be the target R.F. power of 200W, the substrate R.F. power of 20W, the Ar pressure of 6mTorr, and the electrode distance of 6cm. From the refractive index data, the existence of the strong interaction between the electrode distance and Ar pressure was confirmed, and so was the large effect of the electrode distance on transmittance. According to the analysis of TEM and XRD, the closer the electrode distance was, the finer was the grain size due to the high deposition rate. However, the closer electrode distance brought the negative effect on the morphology of the film and caused the reduction of transmittance. AFM and SEM analyses showed that the closer the electrode distance was, the worse was the morphology due to the high rate of the deposition. Under optimum condition, the deposited thin film showed a good morphology and dense microstructure with less defects.

• Journal of the Korean Society of Radiology
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• v.4 no.2
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• pp.21-25
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• 2010

Recently, various semiconductor compounds as radiation detection material have been researched for a diagnostic x-ray detector application. In this paper, we have fabricated the CdS detecton sensor that has good photosensitivity and high x-ray absorption efficiency among other semiconductor compounds, and evaluated the application feasibility by investigating the detection properties about energy range of diagnostic x-ray generator. We have fabricated the line voltage selector(LCV) for a signal acquisition and quantities of CdS sensor, and designed the voltage detection circuit and rectifying circuit. Also, we have used a relative relation algorithm according to x-ray exposure condition, and fabricated the interface board with DAC controller. Performance evaluation was investigated by data processing using ANOVA program from voltage profile characteristics according to resistive change obtained by a tube voltage, tube current, and exposure time that is a exposure condition of x-ray generator. From experimental results, an error rates were reduced according to increasing of a tube voltage and tube current, and a good properties of 6%(at 90 kVp) and 0.4%(at 320 mA) ere showed. and coefficient of determination was 0.98 with relative relation of 1:1. The error rate according to x-ray exposure time showed exponential reduction because of delayed response velocity of CdS material, and the error rate has 2.3% at 320 msec. Finally, the error rate according to x-ray dose is below 10%, and a high relative relation was showed with coefficient of determination of 0.9898.

• Journal of Life Science
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• v.26 no.2
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• pp.174-180
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• 2016

Dicumarol is a coumarin derivative isolated from sweet clover (Melilotus alba), and has anti-coagulant activity with the inhibitory activity of NAD(P)H quinone oxidoreductase1 (NQO1). NQO1 catalyzes the two-electron reduction of quinones to hydroquinones. Dicumarol competes with NAD(P)H for binding to NQO1, resulting in the inhibition of NQO1 enzymatic activity. The expression of matrix metalloproteinases (MMPs) has been implicated in the invasion and metastasis of cancer cells. The expression of MMPs is regulated by cytokines and signal transduction pathways, including those activated by phorbol myristate acetate (PMA). However, the effects of dicumarol on metalloproteinase (MMP)-9 expression and activity are not investigated here. This study investigated whether dicumarol inhibits MMP-9 expression and activity in PMA-treated human renal carcinoma Caki cells. Dicumarol markedly inhibited the PMA-induced MMP-9 mRNA expression and MMP-9 activity. NF-κB and AP1 promoter activity, which is important in MMP-9 expression, also decreased in dicumarol-treated cells. Furthermore, dicumarol markedly suppressed the ability of PMA-mediated migration in Caki cells. When the relevance of NQO1 in the dicumarol-mediated inhibitory effect on PMA-induced MMP9 activity was elucidated, knock-down of NQO1 with siRNA was found to have no effect on PMA-induced MMP9 activity, suggesting that the stimulating effect of dicumarol on PMA-induced MMP9 activity is independent of NQO1 activity. Taken together, the present studies suggested that dicumarol may inhibit PMA-induced migration via down-regulation of MMP-9 expression and activity.