• Journal of Communications and Networks
• /
• 제11권1호
• /
• pp.47-56
• /
• 2009

We investigate the connectivity of fading wireless ad-hoc networks with a pair of novel connectivity metrics. Our first metric looks at the problem of connectivity relying on the outage capacity of MIMO channels. Our second metric relies on a probabilistic treatment of the symbol error rates for such channels. We relate both capacity and symbol error rates to the characteristics of the underlying communication system such as antenna configuration, modulation, coding, and signal strength measured in terms of signal-to-interference-noise-ratio. For each metric of connectivity, we also provide a simplified treatment in the case of ergodic fading channels. In each case, we assume a pair of nodes are connected if their bi-directional measure of connectivity is better than a given threshold. Our analysis relies on the central limit theorem to approximate the distribution of the combined undesired signal affecting each link of an ad-hoc network as Gaussian. Supported by our simulation results, our analysis shows that (1) a measure of connectivity purely based on signal strength is not capable of accurately capturing the connectivity phenomenon, and (2) employing multiple antenna mobile nodes improves the connectivity of fading ad-hoc networks.

• Archives of Pharmacal Research
• /
• 제26권10호
• /
• pp.868-873
• /
• 2003

Ginsenosides, major active ingredients of Panax ginseng, that exhibit various pharmacological and physiological actions are transformed into compound K (CK) or M4 by intestinal microorganisms. CK is a metabolite derived from protopanaxadiol (PD) ginsenosides, whereas M4 is a metabolite derived from protopanaxatriol (PT) ginsenosides. Recent reports shows that ginsenosides might playa role as pro-drugs for these metabolites. In present study, we investigated the effect of bovine serum albumin (BSA), which is one of major binding proteins on various neurotransmitters, hormones, and other pharmacological agents, on ginsenoside $Rg_{2-}$, CK-, or M4-induced regulation of $\alpha3\beta4$ nicotinic acetylcholine (ACh) receptor channel activity expressed in Xenopus oocytes. In the absence of BSA, treatment of ACh elicited inward peak current ($I_{Ach}$) in oocytes expressing $\alpha3\beta4$ nicotinic ACh receptor. Co-treatment of ginsenoside $Rg_2$, CK, or M4 with ACh inhibited IAch in oocytes expressing $\alpha3\beta4$ nicotinic ACh receptor with reversible and dose-dependent manner. In the presence of 1% BSA, treatment of ACh still elicited $I_{Ach}$ in oocytes expressing $\alpha3\beta4$ nicotinic ACh receptor and co-treatment of ginsenoside $Rg_2$ or M4 but not CK with ACh inhibited $I_{Ach}$ in oocytes expressing $\alpha3\beta4$ nicotinic ACh receptor with reversible and dose-dependent manner. These results show that BSA interferes the action of CK rather than M4 on the inhibitory effect of $I_{Ach}$ in oocytes expressing $\alpha3\beta4$ nicotinic ACh receptor and further suggest that BSA exhibits a differential interaction on ginsenoside metabolites.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권2호
• /
• pp.609-617
• /
• 2013

Renal cell carcinomas make up 3% of all cancers and one in four patients is metastatic at time of diagnosis. This cancer is one of the most resistant to cytotoxic chemotherapy. Studies have shown that the efficiency of interferon-alpha and/or interleukin-2 based immune therapies is limited in patients with metastatic renal cell carcinoma but latest advances in molecular biology and genetic science have resulted in better understanding of its biology. Tumor angiogenesis, tumor proliferation and metastasis develop by the activation of signal message pathways playing a role in the development of renal cell carcinomas. Better definition of these pathways has caused an increase in preclinic and clinical studies into target directed treatment of renal cell carcinoma. Many recent studies have shown that numerous anti-angiogenic agents have marked clinical activity. In this article, the focus is on general characteristics of molecular pathways playing a major role in renal cell carcinoma, reviewing clinical information onagents used in the target directed treatment of metastatic lesions.

• Nuclear Engineering and Technology
• /
• 제50권3호
• /
• pp.526-530
• /
• 2018

Human fingernails were used to estimate the radiation dose via electron paramagnetic resonance measurements of radiation-induced radicals. The limiting factors in this research were mechanically induced electron paramagnetic resonance signals due to the mechanical stress during the preparation of the samples. Therefore, different treatment methods of fingernails were used to reduce the mechanically induced signals. The results demonstrate that the mechanically induced and radiation-induced signals have apparently different microwave power saturation behaviors. In addition, the mechanically induced signal shows a fading evolution over time and reaches a constant value. Chemical treatment using the different reagents showed that the minimum mechanically induced signal was obtained using the dithiothreitol reagent. The dose-response curves of the samples treated with dithiothreitol for 30 minutes demonstrated a greater linearity than those of samples treated for 5 minutes. Therefore, to find an unknown absorbed dose in a fingernail sample using a calibration curve, we recommend adopting the mentioned chemical treatment procedure to reduce the uncertainty.

• 대한전자공학회논문지
• /
• 제10권6호
• /
• pp.25-44
• /
• 1973

원인과 결과간의 위상과 work사이의 관계를 correlation function의 견지에서 검토하였고 continuous signal에 포함되어 있는 redundancy를 지적하여 sampling취급의 근거를 auto correlation면에서 보였다. 두 신호사이의 Correlation의 시간변동을 보여줄 수 있는 Time Dependent Correlation Function을 정의하여 PLL회로에서 그 유편성을 보였다. 끝으로 다상포낙선검파법에 의한 특성의 개선을 T.D.Correlation Furction에 의한 Correlation Analysis를 통하려 입증하였다.

• 대한교통학회지
• /
• 제5권2호
• /
• pp.5-18
• /
• 1987

Buses arrive at a traffic intersection later than passenger cars by the amount of dwell time at previous bus stops. This late arrival of buses affects the total passenger delay at intersections especially in the street carrying large bus volume. The bus progression signal system in which the signal offset is given in favor of bus platoons was applied in the case area of Kangnam street in Seoul, and various effects were analyzed using the TRANSYT-7F simulation model. It was observed that the total passenger delay can be reduced significantly if the bus progression signal system is applied, and the most effective bus priority treatment is proved to be the bus progression signal system installed with exclusive bus lanes.

• 한국ITS학회 논문지
• /
• 제5권1호
• /
• pp.21-30
• /
• 2006

중앙버스전용차로제가 도입됨에 따라 서울의 도로환경은 단기간에 급격하게 변하였으며, 이러한 급격한 변화에 미리 준비되지 못하였던 신호운영상의 문제점들이 경험되고 있다. 장 임계적인 문제점으로 중앙버스전용차로 설치구간 신호교차로에서 일반차량 좌회전 진행을 허용할 경우, 현재 우리나라가 규정하고 있는 차량 4색신호등의 한계로 인한 신호의 비효율적 운영이다. 중앙버스전용차로 설치구간 신호교차로에서 일반차량 좌회전의 현실적 운영방안 마련이 필요하다. 본 연구는 중앙차로전용신호의 도입을 준비하기 위하여 교통관제센터의 신호운영모드별 선행좌회전 및 후행좌회전 운영방안을 검토하고, 각 운영방안 별 Signal Map 구성방안을 점검한다. Signal Map 작성방안을 검토한 결과 기존의 신호제어 장비에 추가의 신호등기신호보드를 활용하는 방법으로 제안된 방법의 현장 적용이 용이한 것으로 확인되었다.

• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 1994년도 추계학술대회 논문집
• /
• pp.670-675
• /
• 1994

Yhis paper describes a fault diagnosis simulation of the Real-Time Multiple Fault Dignosis System (RTMFDS) for forcasting faults in a system and deciding current machine state from signal information. Comparing with other diagnosis system for single fault,the system developed deals with multiple fault diagnosis,comprising two main parts. One is a remotesignal generating and transimission terminal and the other is a host system for fault diagnosis. Signal generator generate the random fault signal and the image information, and send this information to host. Host consists of various modules and agents such as Signal Processing Module(SPM) for sinal preprocessing, Performence Monotoring Module(PMM) for subsystem performance monitoring, Trigger Module(TM) for multi-triggering subsystem fault diagnosis, Subsystem Fault Diagnosis Agent(SFDA) for receiving trigger signal, formulating subsystem fault D\ulcornerB and initiating diagnosis, Fault Diagnosis Module(FDM) for simulating component fault with Hierarchical Artificial Neural Network (HANN), numerical models and Hofield network,Result Agent(RA) for receiving simulation result and sending to Treatment solver and Graphic Agent(GA). Each agent represents a separate process in UNIX operating system, information exchange and cooperation between agents was doen by IPC(Inter Process Communication : message queue, semaphore, signal, pipe). Numerical models are used to deseribe structure, function and behavior of total system, subsystems and their components. Hierarchical data structure for diagnosing the fault system is implemented by HANN. Signal generation and transmittion was performed on PC. As a host, SUN workstation with X-Windows(Motif)is used for graphic representation.

• Geosystem Engineering
• /
• 제21권5호
• /
• pp.251-261
• /
• 2018

With the urbanization in recent years, the power line interference noise in electromagnetic signal is increasing day by day, and has gradually become an unavoidable component of noises in magnetotelluric signal detection. Therefore, a kind of power line interference noise elimination method based on independent component analysis in wavelet domain for magnetotelluric signal is put forward in this paper. The method first uses wavelet decomposition to change single-channel signal into multi-channel signal, and then takes advantage of blind source separation principle of independent component analysis to eliminate power line interference noise. There is no need to choose the layer number of wavelet decomposition and the wavelet base of wavelet decomposition according to the observed signal. On the treatment effect, it is better than the previous power line interference removal method based on independent component analysis. Through the de-noising processing to actual magnetotelluric measuring data, it is shown that this method makes both the apparent resistivity curve near 50 Hz and the phase curve near 50 Hz become smoother and steadier than before processing, i.e., it effectively eliminates the power line interference noise.

• 대한방사선치료학회지
• /
• 제28권2호
• /
• pp.149-159
• /
• 2016

목 적 : 폐암환자의 호흡동조 방사선 치료 계획 시 호흡 훈련 전후 RPM 신호와 횡격막 위치 변화를 분석하여 호흡 훈련의 유용성을 평가하고자 한다. 대상 및 방법 : 2016년 4월부터 8월까지 호흡 동조 방사선 치료를 받는 환자 11명을 대상으로 호흡 훈련을 시행하였고 동시에 RPM 신호 및 횡격막 영상을 획득하였다. 호흡 훈련은 총 3단계로 1단계 자유 호흡 상태의 신호 획득, 2단계 호흡 신호 가이드를 통한 1차 호흡 신호 획득, 3단계 설명과 반복 훈련으로 규칙성과 안정을 유도한 최종 호흡 신호를 획득 하였다. 각 단계의 흡기와 호기시 RPM 신호와 투시 영상의 횡격막 위치의 평균값, 표준편차, 최대값, 최소값을 구하고, 이를 1단계 값으로 표준화 하여 2, 3단계를 상대분포 백분율(%)로 변환하여 환자의 호흡 변화와 내부 움직임을 분석 함으로써 각 환자의 호흡훈련 유용성을 평가 하였다. 결 과 : RPM 신호와 횡격막 진폭을 측정한 뒤, 1단계를 100%으로 표준화하여 각 단계의 평균값과 표준편차의 오차 평균을 구하였다. 그 결과, 3단계 최종호흡 획득 시 진폭의 상대평균 및 표준편차 모두 감소가36.4%, 표준편차만 감소가 18.2%, 진폭만 감소가 36.4%로 나타났으며, 횡격막 영상의 위치 측정 시 3단계에서 전체 81.8%의 환자에게서 상대평균 진폭 값이 30% 감소함을 보였다. 그러나 모든 환자들에게서 2단계 대비 3단계의 RPM 신호와 횡격막 진폭이 각각 평균 52.6%, 42.1% 감소함을 보였다. 또한, RPM 신호와 횡격막 영상 진폭 차이의 연관성은 2번 10번 환자를 제외하고 각각 1, 2, 3단계 움직임의 패턴이 상관관계를 보였다. 결 론 : 호흡 동조 방사선치료에서 호흡 훈련을 시행하였을 때 최적화된 호흡 주기를 유도할 수 있었으며, 모의 호흡 훈련을 치료 전 시행함으로써 불규칙적인 호흡에 의한 환자의 호흡을 제어해 폐의 움직임을 예측 가능 하게 해주는 효과를 기대할 수 있었다. 궁극적으로는 방사선 치료의 체계적 오류를 최소화해 보다 정확한 치료를 기대할 수 있어 호흡 훈련이 유용하다고 할 수 있겠다.그러나 본 연구는 치료 전 호흡 훈련을 시행한 자료를 바탕으로 분석한 연구로 제한되어 있으며 추후 실제 CT 계획과 치료 시 획득한 자료를 가지고 검증하는 것도 필요할 것으로 사료된다.