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The Prognostic Role of B-type Natriuretic Peptide in Acute Pulmonary Thromboembolism (급성 폐혈전색전증 환자에서 예후 인자로서 혈중 BNP의 의의)

  • Lee, Su Jin;Lee, Jae Hyung;Park, Ji Young;Jo, Woo Sung;Kim, Ji Eun;Kim, Ki Uk;Park, Hye Kyung;Kim, Yun Seong;Lee, Min Ki;Park, Soon Kew
    • Tuberculosis and Respiratory Diseases
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    • v.60 no.5
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    • pp.540-547
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    • 2006
  • Background : Vital stability and right side heart failure are major prognostic factors of acute pulmonary thromboembolism. While it is important to recognize right side heart failure, it is often difficult in real practice. Recently, several studies have described early diagnostic tools for detecting right side heart failure including echocardiography and biochemical markers. This study, we evaluated the prognostic role of the B-type natriuretic peptide (BNP) in an acute pulmonary thromboembolism. Methods : Thirty-four patients with a diagnosis of acute pulmonary thromboembolism were enrolled in the study. The BNP levels were measured and echocardiography was performed at the Emergency Department. Data on the prognostic factors including ventilatory support, vital stability, pulmonary artery pressure, degree of tricuspid valve regurgitation, complications and death was collected from the patients' medical records. The patients with an acute pulmonary thromboembolism were divided into two groups based on the vital stability and the BNP level and the cutoff values and prognostic factors of the two groups were compared. Results : The predictors of the vital stability that influence the prognosis of patients with acute pulmonary thromboembolism were the BNP level, ventilatory support and death. The plasma BNP levels showed a strong correlation with the vital stability, ventilatory support, thrombolytic therapy and death. When the BNP cutoff level was set to 377.5 pg/dl in a ROC curve, the sensitivity and the specificity for differentiating between the groups with stable or unstable vital signs was 100% and 90%, respectively. Conclusion : This study indicates that a measurement of the plasma BNP levels may be a useful prognostic marker in patients with an acute pulmonary thrombo-embolism.

Supraclavicular Brachial Plexus block with Arm-Hyperabduction (상지(上肢) 외전위(外轉位)에서 시행(施行)한 쇄골상(鎖骨上) 상완신경총차단(上腕神經叢遮斷))

  • Lim, Keoun;Lim, Hwa-Taek;Kim, Dong-Keoun;Park, Wook;Kim, Sung-Yell;Oh, Hung-Kun
    • The Korean Journal of Pain
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    • v.1 no.2
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    • pp.214-222
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    • 1988
  • With the arm in hyperabduction, we have carried out 525 procedures of supraclavicular brachial plexus block from Aug. 1976 to June 1980, whereas block with the arm in adduction has been customarily performed by other authors. The anesthetic procedure is as follows: 1) The patient lies in the dorsal recumbent position without a pillow under his head or shoulder. His arm is hyperabducted more than a 90 degree angle from his side, and his head is turned to the side opposite from that to be blocked. 2) An "X" is marked at a point 1 cm above the mid clavicle, immediately lateral to the edge of the anterior scalene muscle, and on the palpable portion of the subclavian artery. The area is aseptically prepared and draped. 3) A 22 gauge 3.5cm needle attached to a syringe filled with 2% lidocaine (7~8mg/kg of body weight) and epineprine(1 : 200,000) is inserted caudally toward the second portion of the artery where it crosses the first rib and parallel with the lateral border of the muscle until a paresthesia is obtained. 4) Paresthesia is usually elicited while inserting the needle tip about 1~2 em in depth. If so, the local anesthetic solution is injected after careful aspiration. 5) If no paresthesia is elicited, the needle is withdrawn and redirected in an attempt to elicit paresthesia. 6) If, after several attempts, no paresthesia is obtained, the local anesthetic solution is injected into the perivascular sheath after confirming that the artery is not punctured. 7) Immediately after starting surgery, Valium is injected for sedation by the intravenous route in almost all cases. The age distribution of the cases was from 11 to 80 years. Sex distribution was 476 males and 49 females (Table 1). Operative procedures consisted of 103 open reductions, 114 skin grafts combined with spinal anesthesia in 14, 87 debridements, 75 repairs, i.e. tendon (41), nerve(32), and artery (2), 58 corrections of abnormalities, 27 amputations above the elbow (5), below the elbow (3) and fingers (17), 20 primary closures, 18 incisions and curettages, 2 replantations of cut fingers. respectively (Table 2). Paresthesia was obtained in all cases. Onset of analgesia occured within 5 minutes, starting in the deltoid region in almost all cases. Complete anesthesia of the entire arm appeared within 10 minutes but was delayed 15 to 20 minutes in 5 cases and failed in one case. Thus, our success rate was nearly 100%. The duration of anesthesia after a single injection ranged from $3\frac{1}{2}$ to $4\frac{1}{2}$, hours in 94% of the cases. The operative time ranged from 0.5 to 4 hours in 92.4% of the cases(Table 3). Repeat blocks were carried out in 33 cases when operative times which were more than 4 hours in 22 cases and the others were completed within 4 hours (Table 4). Two patients of the 33 cases, who received microvasular surgery were injected twice with 2% lidocaine 20 ml for a total of $13\frac{1}{2}$ hours. The 157 patients who received surgery on the forearms or hands had pneumatic tourniquets (250 torrs) applied without tourniquet pain. There was no pneumothorax, hematoma or phrenic nerve paralysis in any of the unilateral and 27 bilateral blocks, but there was hoarseness in two, Horner's syndrome in 11 and shivering in 7 cases. No general seizures or other side effects were observed. By 20ml of 60% urcgratin study, we confirm ed the position of the needle tip to be in a safer position when the arm is in hyperabduction than when it is in adduction. And also that the humoral head caused some obstraction of the distal flow of the dye, indicating that less local anesthetic solution would be needed for satisfactory anesthesia. (Fig. 3,4).

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Studies on the method of bring to perfectly from defective cutting Sapling (삽목재육묘의 육함에 관한 연구)

  • 김문협
    • Journal of Sericultural and Entomological Science
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    • no.11
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    • pp.31-44
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    • 1970
  • This experiment is conducted fer method cf bring to perfectly from defective cutting sapling 25 a production method of sapling which is to substitute for conventional graf ting. 1. In green wood cutting root comes out after 15 days of cutting with nearly straight development of root system; after 40 days of cutting, roots with total length of 1119 mms 43 roots, and 5.4 grs a root in total weight obtained. 2. Survival percentage of green wood cutting ranges between 56% and 90%, average 73% of that and it varies with natural characteristics of varietes. The results show variety of Gaeryang-Suban and Iljiroe with 80% as a best ones in contrast with the variety of Shipyung. 3. The varietics or Gaeryang-Suban. Iljiroe, Suwon-Sang No.4, Rosang makes of much more roots than Yongchonchuwoo and Shipyung do. 4. Root ability made good number of roots commercially, when cutting is conducted soaking in 0.01 % NAA solution or 0.02% NAA solution for 2 or 3 seconds as a chemical promoter. 5. Economical measures for increase of scion adapted 1) 2 scions from a green wood 50 cm long should be taken and basal pan of scion at its middle portion should be cut right under the node. 2) Scions below 50cm long may be used. Small scions or growthceased shoots h3ve also considerable root ability enough to be used. 3) Thus far, up 100,000 scions might be produced in 10 a. 6. We can find number of root increased, when cutting the opposite side in obliquity manner at 450. 7. When 110,000 saplings in 10 a. for the production of bring to perfectly from defective cutting sapling planted, quality of stocks does not go to bad condition without any obstacles in practical use. 8. Although the times or grafting delayed until middle of July, quality of sapling goes just a little down. Grafting may be conducted from early June to middle of July separately in several times, and the green wood of prunned mulberry in spring is available for a scion after end of June. 9. 10 grs weight of defective cutting sapling makes 95% of complete sapling, otherwise 5 or 10 grs in weight of one becomes 80% of complete sapling with its quality as similar as grafted one. 10. When the sapling planted, its branches should be cut, leaving 3 or 4 buds at the bottom of new branches. 11. In view of economical stand point, production cost of bring to perfectly from defective cutting sapling obtains 52% of grafting cost.

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A Fundamental Study of the Armors of the Missionsmuseum St. Ottilien in Germany (독일 상트 오틸리엔 선교분도수도원 선교박물관 소장 갑옷에 관한 기초연구)

  • Cho, Woo Hyun;Yum, Jung Ha;Beckers-Kim, Young Ja
    • Journal of the Korean Society of Costume
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    • v.65 no.3
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    • pp.76-90
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    • 2015
  • This is a basic study of the two remaining armors (artifacts number K2366, K2368) from the late Joseon dynasty that is part of the Korean costume collection, which is preserved in the Mission Museum of Saint Ottilien in Germany. The armor No. 1 (artifacts number K2366) is a coat-styled armor with brass studs. It has a U-shaped neckline with the non-overlapping collars and sleeve straight-lined inseam. The armor No. 1 has the Mu to the sides and is not back slit. Both its inner and outer material are padded with cotton. Leather mails are attached on the inner lining, and studs are attached on the outer lining to match the leather mails. For this reason, the armor No. 1 can be named MyeonPiGab (brass studded armor consisting of a cotton coat with internal leather mails). The outer material is faded to have the natural white, or antique white look and the patterns on it are indigo blue. The inner material is blue, but the original color is unknown since it is faded. The lotus blossoms and vine patterns are dyed on the surface of the outer material and a name is written on the inner material. The armor No. 1 was worn between the late 17th century and the 19th century. It is estimated that it was worn by military officers who were above the mid-rank in the end of the Joseon dynasty. The armor No. 2 (artifacts number K2368) is a coat-styled armor with brass studs and a low-cut U-shaped neckline. The armor No. 2 has a slit on the left armpit and a string around it. Studs are evenly attached on the armor. The iron mails are attached to the left chest area on its inner lining. It seems that it was designed with both formality and functionality in mind. The outer material is red flannel, the inner material is blue satin and the pads are cheesecloth. The side of its collars, cuffs, front lines, sidelines, back slit, and bottom lines are trimmed with fur. There are armors called "JeonCheolGap (brass studded armor consisting of a felt coat with internal iron mails)," which is similar to the armor No. 2, however, the similarities are limited because they are not made of the same material nor do they follow the same principle of nomenclature.

IN VITRO STUDY OF THE TENSILE BOND STRENGTH OF CEMENT-RETAINED SINGLE IMPLANT PROSTHESIS BY THE VARIOUS PROVISIONAL LUTING CEMENTS AND THE SURFACE TREATMENT OF ABUTMENTS

  • Lee, Hwa-Yeon;Lee, Ho-Sang
    • The Journal of Korean Academy of Prosthodontics
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    • v.40 no.3
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    • pp.296-305
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    • 2002
  • The main disadvantage of cement-retained implant restorations is their difficulty in retrievability. Advocates of cemented implant restorations frequently state that retrievability of the restoration can be maintained if a provisional cement is used. The purpose of this study was to find the optimal properties of provisional luting cements and the surface treatment of abutments in single implant abutment system. 30 prefabricated implant abutments, height 8mm, diameter 6mm, 3-degree taper per side, with light chamfer margins were obtained. Three commercially available provisional luting agents which were all zinc oxide eugenol type ; Cavitec, TempBond and TempBond NE were evaluated. No cement served as the control. TempBond along with vaseline, a kind of petrolatum (2:1 ratio) was also evaluated. Ten out of thirty abutments were randomly selected and abutment surfaces were sandblasted with $50{\mu}m$ aluminum oxide. Another ten abutments were sandblasted with $250{\mu}m$ aluminum oxide. A vertical groove, 1 mm deep and 5mm long was cut in each twenty abutments. Ten of them were sandblasted with $50{\mu}m$ aluminum oxide. The full coverage casting crowns were cemented to the abutments with the designated provisional luting agent. Specimens were stored in distilled water at $37^{\circ}C$ for 24 hours. Each specimen was attached to a universal testing machine. A crosshead speed of 0.5mm/min was used to apply a tensile force to each specimen. Within the limitations of this in vitro study, the following conclusions were drawn: 1. Tensile bond strength of provisional luting cements in no surface treatment decreased with the sequence of TempBond NE, TempBond, Cavitec, TempBond with vaseline, no cement. 2. Tensile bond strength more increased by surface treatment. Sandblasting with $250{\mu}m$ aluminum oxide exhibited the highest tensile bond strength in the abutment cemented with TempBond NE and sandblasting with $50{\mu}m$ aluminum oxide exhibited the highest tensile bond strength in cemented with TempBond. 3. In the aspect of a groove formation, tensile bond strength significantly increased in TempBond with vaseline only and the others had no significant effect on tensile bond strength.

Analysis of the Redox Reaction for Polypyrrole Thin Film by Using a Quartz Crystal Analyzer (수정진동자 분석기(QCA)를 이용한 폴리피롤 박막의 산화-환원반응 해석)

  • Chang, Sang-Mok;Kim, Jong-Min;Park, Ji-Sun;Son, Tae-Il;Hiroshi, Muramatsu
    • Applied Chemistry for Engineering
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    • v.9 no.1
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    • pp.44-51
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    • 1998
  • In this work, the in-situ viscoelastic characteristics of electropolymerized polypyrrole (PPy) thin film were investigated in the electrolyte solutions of $NaClO_4$, $LiClO_4$, and $KClO_4$ by using quartz crystal analyzer (QCA). One side of quartz crystal was used as a working electrode mounted in a special fabricated QCA electrochemical ceil. The resonant frequency and resonant resistance diagram (F-R diagram) was used to interpret the viscoelastic characteristics of Pby thin film and compared with AFM photograph. The resonant frequency, resonant resistance, and current were measured to analyze the redox reaction behaviors when the cyclic voltammetry was performed using AT-cut quartz crystal electrode coated with galvanostatically polymerized Ppy film. The result suggests that the Ppy film polymerized onto the crystal behaves as a rigid elastic layer at the initial stage of electropolymerization, while the film becomes a viscoelastic layer the polymerization proceeds further. At the same time, the film thickness increases and some morphological changes take place due to the penetration of electrolyte solution into the film. These phenomena take place when cyclic voltammetry was performed using different electrolyte solution compared with polymerization process.

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Comparative Study of Relationship between the Depressive Tendency and Tenderness of Alarm Points and Transport Points (우울 경향과 복모혈(腹募穴), 배유혈(背兪穴)압통과의 관계 비교 연구)

  • Suh, Min-Jung;Kim, Song-Yi;Park, Young-Jae;Jung, Won-Mo;Cha, Su-Jin;Lee, Hyang-Sook;Lee, Hye-Jung;Park, Hi-Joon
    • Korean Journal of Acupuncture
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    • v.27 no.4
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    • pp.97-109
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    • 2010
  • Objective : To examine whether any correlation between tendency towards depression and tenderness at special acupuncture points exists, thus to explore the potential diagnostic property of acupuncture points. Methods : A total 31 subjects were included in this study. They filled out questionnaires about their mental [Beck Depression Inventory (BDI), Stress Response Inventory (SRI), Profile of Mood States (POMS)] and physical (fatigue due to overexertion, and food accumulation) symptoms. Identical weight around Alarm points (CV17, CV12, ST25, CV5, CV4, and LR13) and transport points (BL14, BL20, BL21, BL22, BL25, and BL27) was given using an algometer and the subjects rated their pain on an 11-point numerical rating scale. Heart rate variability (HRV) was also measured. Results : The subjects were divided into two groups, normal and depressive tendency groups with a cut-off point of nine on BDI. The depressive tendency group reported significantly higher values in SRI, POMS, and questionnaire for fatigue due to overexertion. In the pressure pain measurement, depressive tendency group had more pressure pain at CV12, left side of BL20, BL14, BL22 and both sides of BL21, BL25, BL27, significantly (each p<0.05). The data of HRV did not show significant differences between groups. Conclusions : People with a tendency towards depression may be prone to stress, negative mood, and fatigue due to overexertion. In addition, they may be more likely to develop tenderness at alarm points and transport points compared with healthy people. Further research is needed to confirm this finding.

Characteristics and Energy Absorbing Capacity for Rockfall Protection Fence from In-Situ Rockfall Tests (현장 낙석실험을 통한 낙석방지울타리의 특성 및 성능 평가)

  • 구호본;박혁진;백영식
    • Journal of the Korean Geotechnical Society
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    • v.17 no.6
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    • pp.111-121
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    • 2001
  • Rockfall protection fences are used for diminishing rockfall damage in roads side slopes. In order to install the fences in effective way, the conditions of rock slopes and total predicted impact energy of fa11ing rock should be considered. However, the fences have been constructed without any consideration for lithology, height and slope angle of rock slope in Korea. In addition, the information about the performance of the protection fences, which should be evaluated by in-situ test or laboratory test in order to check out the practical use in the field, is not available. Therefore, in design manual for the rockfall protection fence, the specific details for the installation of this type of fence are not provided yet. The full sized rockfall in situ test was carried out for the calculation of falling energy of rock and the evaluation of the maximum energy absorbing capacity of fence. For this test, the rock slopes whose heights are about 20 m and dip angle of 65 degree, have been chosen. This is because those geometries are mean height and slope angle of most road cut slopes along Korean national highway. Based on the preliminary simulation procedure, four different sizes of concrete ball (0.7, 1.3, 2.3 and 4.3 ton) were prepared and flour different types of protection fence were constructed. The results of this test provide information about the maximum energy absorbing capacity of the fence, kinetic energy of rockfall and restitution coefficient, and these results can be utilized in the establishment of rockfall fence design and construction manual.

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Surgical treatment of Mallet finger deformity with Hook plate (고리 금속판을 이용한 망치 손가락의 수술적 치료법)

  • Choi, Seok Min;Jung, Sung Gyun;Shin, Ho Seong;Park, Eun Soo;Kim, Yong Bae
    • Archives of Plastic Surgery
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    • v.36 no.3
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    • pp.318-321
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    • 2009
  • Purpose: The bony mallet finger injury is generally managed by conservative treatments, but operative treatments are needed especially when the fractures involve above 30% of articular surface or distal phalanx is accompanied by subluxation in the volar side. This is the reason they often result in chronic instability, articular subluxation and unsatisfactory cosmetic. In this report, We describe new method using the hook plate as an operative treatment of Mallet finger deformity. Methods: Among 13 patients with Mallet finger deformity who came from February 2006 to February 2008, six patient were included in surgical indication. Under local anesthesia, H or Y type incision was made at the DIP joint area. After the DIP joint extension, the hook plate was put on the fracture line, and one self tapping screw was used for fixation. 2 hole plate which was one of the holes in 1.5 mm diameter was cut in almost half and bended through approximately $100^{\circ}$. Results: In all six cases which applied the hook plate, complications such as loss of reduction or nail deformity were not seen. In only one patient, hook pate was removed due to inflammatory reaction after surgery. At 2 weeks after operation, active motion of DIP joint was performed. The result was satisfactory not only cosmetically but also functionally. At 6 weeks after operation, the range of motion of DIP joint was average $64^{\circ}$. Conclusion: The purpose of the operative treatment for mallet finger deformity using the hook plate is to provide anatomical reduction with rigid fixation and to prevent contracture at the DIP joint. While other operations take 6 weeks, the operation using the hook plate begins an active motion at 2 weeks after operation. Complication rate was low and the method is rather simple. Thus, the operation using the hook plate is recommended as a good alternative method of the mallet finger deformity treatment.

Transgenic lettuce (Lactuca sativa L.) with increased vitamin C levels using GalUR gene (GalUR 유전자를 이용한 비타민 C 증대 상추 (Lactuca sativa L.) 형질전환체 개발)

  • Lim, Mi-Young;Cho, Yi-Nam;Chae, Won-Ki;Park, Young-Soo;Min, Byung-Whan;Harn, Chee-Hark
    • Journal of Plant Biotechnology
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    • v.35 no.2
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    • pp.115-120
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    • 2008
  • L-Ascorbic acid (vitamin C) in vegetables is an essential component of human nutrition. The objective is to transform lettuce (Lactuca sativa L.) with GalUR gene that is involved in the vitamin C biosynthesis. The cotyledons of Hwoahong (Nongwoo Bio Co.) were used to induce the callus and shoot under the selection media with MS + 30 g/L Sucrose + 0.5 mg/L BAP + 0.1 mg/L NAA + 100 mg/L kanamycin + 200 mg/L lilacillin, pH 5.2. The shoot was developed from the cut side of the explants after 3 weeks on the selection media. We successfully transformed the lettuce with GaIUR gene and analyzed the levels of vitamin C. We found that some of the lettuce transgenic lines contained higher levels of vitamin C compared with the normal one (non-transformed). Especially, some of $T_1$ lettuces inserted by GalUR showed about $3{\sim}4$ times higher content of vitamin C compared to the non-transformed lettuce. This data support the previously work performed with GLOase transgenic $T_1$ lettuces from which several times higher content of vitamin C were identified. The $T_2$ lettuces with high content of vitamin C have been selected for further analysis.