• Asian Journal of Turfgrass Science
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• v.10 no.2
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• pp.105-115
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• 1996

To find out the mineral cycles of calcium, magnesium and sodium in dynamic grassland cosystems in a steady state condition, this investigation was conducted along the northwest side on Mt. Kwanak. The experimental results may he suromarized on the communities of a Zoysia japonica and a Miscanthus sinesis as follows. As compared with some properties of the surface soils among two semi-natural grasslands, cal- cium (Ca) was greater quantity in a Zoysia japonica, whereas, in a Miscanthus sicensis, sodium (Na)and magnesium (Mg) were greater in Mt. Kwanak. For the case of steady production and release, the ratio of annual mineral production to the amount accumulated on the top of mineral soil in a steady state provides the estimates of release constant k. The release constants of Ca, Mg and Na of the litter were 0.42, 0.25 and 0.29 in the Zoysia japonica grassland, and were 0.41, 0.54 arid 0.62 in the Miscanthus sinensis grassland, respect- ively. The half times of Ca, Mg and Na required for the release or accumulation of the litter on the grassland were 1.65, 2.77 and 2.39 in the Zoysia japonica, and were 1.69, 1.28 and 1.12 in the Miscauthus sinensis, respectively. The increasing order of the turnover parameters of the elements was Ca, Na and Mg in the Zoysia japonica grassland, and was Na, Mg and Ca in the Miscanthus Si nens is grassland. The amounts of annual cycles for Ca, Mg, Na in the grassland ecosystem under the steady-state conditions were 1.29, 0.20 and 0.12 g /m$^2$ in the Zoysia japonica grassland and 3.91, 1.04 and 0.61 g /m$^2$ in the Miscanthus sinensis grassland.

• Journal of the Korean Society of Marine Environment & Safety
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• v.9 no.2
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• pp.73-77
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• 2003

This study focuses on illustrating the effect of a hill on current filed at a channel, and the topographic effects of the hill were studied with various numerical experiments. The model experiments showed that stratification as well as bottom topography had influence on current fields around the hill. Due to stratification effect, Karman vortex formed behind the hill by bottom topography made effects on water movement only in the deep layer. The vortex reduced density field around the hill which resulted in the stratification in the water column, and which also resulted in the movement of isopycnic surface to deep layer both in front and back of the hill. The water in the back of the hill moved upward along ispycnic surface afterward. From these effects, velocity pattern in vertical direction around the hill showed opposite direction, downwrad in front of the hill and upward in the back. However, the upward flows did not seem to have any significant influence on the water conditions in the surface layer, even though strong upward flows were found on both side of the hill.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9667-9672
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• 2014

Background: Pancreatic adenocarcinoma is a malignant gastrointestinal cancer with significant morbidity and mortality. Despite severe side effects of chemotherapy, the use of immunotherapy combined with chemotherapy has emerged as a common clinical treatment. In this study, we investigated the efficacy of the combined doxorubicin and interferon-${\alpha}$ (IFN-${\alpha}$) therapy on murine pancreatic cancer Panc02 cells in vitro and in vivo and underlying mechanisms. Materials and Methods: A Panc02-bearing mouse model was established to determine whether doxorubicin and interferon-${\alpha}$ (IFN-${\alpha}$) could effectively inhibit tumor growth in vivo. Cytotoxicity of natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) was evaluated using a standard LDH release assay. To evaluate the relevance of NK cells and CD8 T cells to the combination therapy-mediated anti-tumor effects, they were depleted in tumor-bearing mice by injecting anti-asialo-GM-1 antibodies or anti-CD8 antibodies, respectively. Finally, the influence of doxorubicin+interferon-${\alpha}$ (IFN-${\alpha}$) on the ligands of NK and T cells was assessed by flow cytometry. Results: The combination therapy group demonstrated a significant inhibition of growth of Panc02 in vivo, resulting from activated cytotoxicity of NK cells and CTLs. Depleting CD8 T cells or NK cells reduced the anticancer effects mediated by immunochemotherapy. Furthermore, the doxorubicin+IFN-a treatment increased the expression of major histocompatibility complex class I (MHC I) and NKG2D ligands on Panc02 cells, suggesting that the combined therapy may be a potential strategy for enhancing immunogenicity of tumors. All these data indicate that the combination therapy using doxorubicin and interferon-${\alpha}$ (IFN-${\alpha}$) may be a potential strategy for treating pancreatic adenocarcinoma.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.11
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• pp.4929-4934
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• 2016

Cancer, a worldwide epidemic disease with diverse origins, involves abnormal cell growth with the potential to invade other parts of the body. Globally, it is the main cause of mortality and morbidity. To overcome the drawbacks of the commercially available chemotherapies, natural products-loaded nano-composites are recommended to improve cancer targetability and decrease the harmful impact on normal cells. This study aimed at exploring the anti-cancer impacts of Moringa oleifera seed oil in its free- (MO) and nano-formulations (MOn) through studying whether it mechanistically promotes mitochondrial apoptosis-mediating cell death. Mitochondrial-based cytotoxicity and flow cytometric-based apoptosis analyses were performed on cancer HepG2, MCF7, HCT 116, and Caco-2 cell lines against normal kidney BHK-21 cell line. The present study resulted that MOn triggered colorectal cancer Caco-2 and HCT 116 cytotoxicity via mitochondrial dysfunction more powerful than its free counterpart (MO). On the other side, MOn and MO remarkably induces HCT 116 mitochondrial apoptosis, while sparing normal BHK-21 cells with minimal cytotoxic effect. The present results concluded that nano-micelle of Moringa oleifera seed oil (MOn) can provide a novel therapeutic approach for colorectal and breast cancers via mitochondrial-mediated apoptosis, while sparing normal and even liver cancer cells a bit healthy or with minimal harmful effect. Intriguingly, MOn induced breast cancer not hepatocellular carcinoma cell death.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.16 no.1
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• pp.11-21
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• 2020

This study aims to develop and advance the evaluation technology for assessing PHWR safety. For this purpose, the complete loss of AC power or station blackout (SBO) was selected as a target accident scenario and the analysis model to evaluate the plant responses was envisioned into the MARS-KS input model. The model includes the main features of the primary heat transport system with a simplified model for the horizontal fuel channels, the secondary heat transport system including the shell side of steam generators, feedwater and main steam line, and moderator system. A steady state condition was achieved successfully by running the present model to check out the stable convergence of the key parameters. Subsequently, through the SBO transient analyses two cases with and without the coolant leakage via the PHTS pumps were simulated and the behaviors of the major parameters were compared. The sensitivity analysis on the amount of the coolant leakage by varying its flow area was also performed to investigate the effect on the system responses. It is expected that the results of the present study will contribute to upgrading the evaluation technology of the detailed thermal hydraulic analysis on the SBO transient of the operating PHWRs.

• Journal of Korean Society of Transportation
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• v.23 no.5 s.83
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• pp.73-81
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• 2005

Triangle-shaped island was been used for the exclusive separation between the right-turn and the through flow. However, in case that existing Triangle-Shaped Island is built at the intersection of narrow road. there are more possibilities of traffic collision trespassing into the opposite lane. Accordingly, separation of the opposite lane is required so as to prevent the intrusion of the large-sized (a heavy) vehicle into the opposite lane turning at the intersection. This study showed the comparison between intersection composed of existing Triangle-Shaped Island and the intersection with Drop Island is added. First of all, in the safety aspect, a method to decide location and shape of Drop Island considering turning trajectory of the large-sized (the heavy vehicle) is addressed. The guideline on the placement of drop island install location and method to decide form the consider heavy truck's turn trajectory in safety side. As a conclusion. we analyzed that drop island is relatively superior to existing Triangle-Shaped Island in terms of driver, ease of driving, driving pleasantness, pedestrian, widening and economic performance aspect.

• Plant Journal
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• v.13 no.1
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• pp.37-43
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• 2017

This study analyzed the change of gas turbine performance with air temperature decrease by the evaporation cooling system in summer season. Gas turbine performance was tested on the condition that ambient temperature is $29{\pm}1^{\circ}C$. As a result, Air temperature at the compressor inlet was decreased by $4.12^{\circ}C$ after the installation of evaporation cooling system. Decreased air temperature followed by increased air density affected gas turbine performance, Which increased compressor pressure ratio by 0.27, improved compressor efficiency of 0.29 %p, improved gas turbine enthalpy drop efficiency of 0.31 %p, improved the gas turbine efficiency by 0.44 %p, improved electric power output by 4,489 kW. On the other side, the influence of the humidity increase and flow resistance increase was negligible.

• Earthquakes and Structures
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• v.6 no.2
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• pp.163-179
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• 2014

Dynamic test with scaled model of a group of intake towers was performed to study the dynamic interaction between water and towers. The test model consists of intake tower or towers, massless foundation near the towers and part of water to simulate the dynamic interaction of tower-water-foundation system. Models with a single tower and 4 towers were tested to find the different influences of the water on the tower dynamic properties, seismic responses as well as dynamic water-tower interaction. It is found that the water has little influence on the resonant frequency in the direction perpendicular to flow due to the normal force transfer role of the water in the contraction joints between towers. By the same effect of the water, maximum accelerations in the same direction on 4 towers tend to close to each other as the water level increased from low to normal level. Moreover, the acceleration responses of the single tower model are larger than the group of towers model in both directions in general. Within 30m from the surface of water, hydrodynamic pressures were quite close for a single tower and group of towers model at two water levels. For points deeper than 30m, the pressures increased about 40 to 55% for the group of towers model than the single tower model at both water levels. In respect to the pressures at different towers, two mid towers experienced higher than two side towers, the deeper, the larger the difference. And the inside hydrodynamic pressures are more dependent on ground motions than the outside.

• Journal of Acupuncture Research
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• v.15 no.2
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• pp.301-310
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• 1998

Infrared thermographic imaging visualizes noninvasively various abnormal condition by detecting the skin temperature. As the imaging represents the objective condition by the changes in blood flow under the control of autonomic nervous system, it is used to diagnosis and monitor the lumboscral radiculopathy. And asymmetry is important in the diagnosis of disc herniation. The most common type of disc herniation occurs psoterolaterally. This frequently causes nerve root compression leading to a radiculopathy in the distribution of the involved nerve root, most of which also provoke the asymmetric changes in thermography. Central disc herniation, which accounts for 5% to 35% of disc herniation, is typically associated with low back pain. But radiculopathy is usually abscent unless central disc heriniaton is large enough to cause compression of the cauda equina. To evalute the diagnostic value of the thermographic imaging in the diagnosis of central disc herniation, the imaging of 15 normal subjects and 48 patients with central disc herniation documented by CT scan were analyzed. The patients had either bilateral radiculophathy or no radiculopathy. The imaging of patient group with non rediculopathy did not show any significant thermal difference to control. While bilateral radiculopathy group reveled hypothermic pattern compared twith control. Thermal difference between left and right side did not present any significance in non radiculopathy group but hypothermia in bilateral radiculopathy group. Large herniation group demonstrated hyperthemic pattern while the others showed no significant change. Cranial caudal thermal difference did not show any difference between experiment groups. These results shows that infrared thermographic imaging can be used central disc herniation with bilateral radiculopathy, while it seems to little useful on the diagnosis of non radiculopathic disc herniation.

• Journal of Digital Convergence
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• v.11 no.4
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• pp.57-69
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• 2013

Progresses in ICT make the processing and exchange of personal data across international borders often necessary and relatively easy. The challenge lies in protecting fundamental rights and freedoms of individuals, notably the right to privacy and the right to personal information, while encouraging the free and secure flow of information across borders for the continued expansion of online transactions. The key to establishing a functioning international solution for personal data protection is to strike a right balance between the two camps which currently dominate the debate - the advocates of individual privacy rights on one side exemplified by the EU, and the proponents of self-regulation and economic efficiency on the other, represented by the U.S. In the face of a growing tension between the two sides each equipped with their own ideals, a practical solution may lie in utilizing established institutions of standardization such as ISO and IEC as a ground upon which an agreement can take its root.