• Journal of Ginseng Research
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• 제3권2호
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• pp.105-112
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• 1979

Effect of gibberllin on the breaking of bud dormancy of root and growth of aerial parts were investigated under laboratory and field condition for the prolongation of shoot growth duration, shortening of fruit bearing age and the increase of root yield. Drop application of GA (0.5ml of 50ppm) on rhizome of one year old root broke bud dormancy better than by low temperature. Soaking for one hour of one year old roots which wintered in the field in GA (50-200ppm) greatly accelerated the emergence of new buds while kinetin was only effective at low level (50ppm). GA substantially increased stem length in early stage and petiole length later on while kinetin increased stem diameter. Under the field condition with polythylene film tunnel (PET) in early spring the soaking in GA (50ppm for 1 hour) of rhizome of 4 year old root with replanting and dropping GA (50ppm, 1ml) on rhizome without replanting brought earlier emergence (29days) in comparison with that in the usual field. PET alone caused 14 day-early emergence. GA increased the length of stem and petiole only in early stage and replanting decreased only petiole length in later stage. Soaking in GA with replanting caused the Pronounced decrease in peduncle length, percentage of (ruin set and dry weight of reproductive organ (fruits and peduncle). Dropping without replanting showed significant decrease only in dry weight of reproductive organ. Fruit maturing was 20 days earlier than in usual held with little difference between GA and PET. It is well expected that GA could be used for early emergence of bud, shortening of root dormancy period, thinning of fruit and higher root yield according to application amount and methods.

• 한국응용과학기술학회지
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• 제1권1호
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• pp.11-21
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• 1984

The purpose of the study was to find an effect of medium chain triglyceride (MCT)diet on the serum lipids and lipoprotein of Sprague-Dawley rats when the were fed with cholesterol. All experiment-groups were fed with different diet such as soybean oil, shortening,MCT and MCT mixed with oil respectively. After fed to each group, the levels of serum lipids and lipoprotein among fed rats were examined and the data from the experiment were compared with a control group. The results obtained from the study are as follows : (1) The average boby weight gain in MCT diet and soybean oil diet groups were lighter than that of the control group, while the food efficiency ratio in each experimental diet group was almost same as than in the control group. (2) Total cholesterol levels in serum of all experimental diet groups were lower than that of the control group except the level in shortening diet group. Especially, the levels of total cholesterol in MCT diet and soybean oil diet groups were significantly lower than that of the control group. (3) VLDL, LDL-cholesterol levels of all experimental groups were almost same except the case of the MCT diet and soybean oil diet group which was significantly low. (4) The ratio of VLDL, LDL-cholesterol to HDL-cholesterol, so called, atherogenic index in serum of MCT and soybean oil diet groups were significantly lower than that of the control group. (5) The ratio of total cholesterol to phospholipids in serum of MCT diet group was decreased, because total cholesterol levels were decreased more than phospolipid levels. (6) The ratio of the serum VLDL, LDL to HDL in MCT diet group. in MCT and soybean oil mixed diet group, and in soybean diet group was decreased. In other wards, it means that the decrease of the serum VLDL, LDL in each group and the increase of the serum HDL.

• Biomolecules & Therapeutics
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• 제20권5호
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• pp.457-462
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• 2012

The stem-bark of Kalopanax pictus (KP, family Araliaceae), of which main constituent is kalopanaxsaponin B, has been used for asthma, rhinitis, and arthritis in Chinese traditional medicine. To clarify anticolitic effect of KP, we examined anti-inflammatory effect of KP extract and kalopanaxsaponin B in lipopolysaccharide (LPS)-stimulated peritoneal macrophage and 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitic mice. Of KP extracts, KP BuOH-soluble fraction most potently inhibited LPS-induced IL-$1{\beta}$, IL-6 and TNF-${\alpha}$ expression, as well as NF-${\kappa}B$ activation. However, KP BuOH fraction increased IL-10, an anti-inflammatory cytokine. KP BuOH fraction also inhibited colon shortening and myeloperoxidase activity in TNBS-induced colitic mice. KP BuOH fraction also potently inhibited the expression of the pro-inflammatory cytokines, IL-$1{\beta}$, IL-6, and TNF-${\alpha}$ as well as the activation of NF-${\kappa}B$. Kalopanaxsaponin B, a main constituent of KP, inhibited TNBS-induced colonic inflammation, including colon shortening, and TNBS-increased myeloperoxidase activity pro-inflammatory cytokine expression and NF-${\kappa}B$ activation in mice. Based on these findings, KP, particularly its main constituent, kalopanaxsaponin B, may ameliorate colitis by inhibiting NF-${\kappa}B$ pathway.

• Journal of Microbiology and Biotechnology
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• 제33권8호
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• pp.1057-1065
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• 2023

Inflammatory bowel disease (IBD), a chronic inflammatory disease, results from dysregulation of the immune responses. Some lactic acid bacteria (LAB), including Lactobacillus, alleviate IBD through immunomodulation. In this study, the anti-colitis effect of LAB isolated from human breast milk was investigated in a mouse model induced acute colitis with 2,4,6-trinitrobenzene sulfonic acid (TNBS). TNBS remarkably increased weight loss, colon shortening, and colonic mucosal proliferation, as well as the expression levels of inflammatory cytokines, including tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-1β. Oral administration of LAB isolated from human breast milk resulted in a reduction in TNBS-induced colon shortening, as well as induced cyclooxygenase (COX)-2, nitric oxide synthase (iNOS), nuclear factor-kappa B (NF-κB). In addition, LAB suppressed inflammatory cytokines such as TNF-α, IL-6, and IL-1β, and thus showed an effect of suppressing the level of inflammation induced by TNBS. Furthermore, LAB alleviated gut microbiota dysbiosis, and inhibited intestinal permeability by increasing the expression of intestinal tight junction protein including ZO-1. Collectively, these results suggest that LAB isolated from human breast milk can be used as a functional food for colitis treatment by regulating NF-κB signaling, gut microbiota and increasing expression of intestinal tight junction protein.

• 한국인쇄학회지
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• 제18권1호
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• pp.121-139
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• 2000

This study is to test the possibility of applying the low-molecular weighted waste cellulase, which is produced in the process of cellulase production, to paper making. After experimenting on high-crystallized non-wood fibers with beating catalyst. I got the result that the condition for the optimal effect is temperature 40~6$0^{\circ}C$, the time 90min to 120min, pH 5.0 to 6.0, the enzyme contents 0.3% and that the effect of beating such as slight reduction of fiver viscosity, increase of water retention value(WRV) and shortening of fiber length was increased with waste cellulase. Through this process, the density, folding endurance, tensile strength and burst strength of paper was remarkably increased, which is inferred to result from the increased flexibility of fiber by individual characteristics of non-wood fiber, which was high-crystallized by penetrated low-molecular weight cellulases in the fiber.

• 한국인쇄학회지
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• 제16권3호
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• pp.157-170
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• 1998

To investigate the most effective way of cellulase utilization on paper making process and the systematic way of how to combine its components for better use, purified two major cellulase were applied to bleached kraft pulp at various dosage in the refining process and estimated the synergism effect of each components in the characteristics of papermaking fiber. freeness was not changed by $C_1$ Component dosage but strongly increased by Cx Component dosage. Drop in fiber viscosity, increase in WQV, fiber shortening and fine generation was strongly influenced by Cx Component, it seems to be that Cx Component works a hydrogenate that breaks hydrogen bonding in fiber and enhances pooling effect of fiber. $C_1$ Component was little influenced these characteristics of fiber but considered to help to make fiber surface smooth.

• Environmental Analysis Health and Toxicology
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• 제8권1_2호
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• pp.11-17
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• 1993

Radioactive elements Li/sup +/, Rb/sup +/and Cs/sup +/ effect the period shortening in proportion to the higher concentration on the growth of Neurospora crassa. 1 mM LiCl presented the result of the period length 0.52 h shorter than average circadian rhythm 21.66 h. 1 mM RbCl reduced the period length 1.13 h than control period 21.89 h and 1 mM CsCl reduced 2.12 h than control period 21.89 h. In the equal concentration Cs/sup +/ had an extreme effect. Fatal doses of Li/sup +/, Rb/sup +/ and Cs/sup +/ are 20mM, 30mM and 20mM. In the fatal concentration Neurospora didn't develop more after 7 days and the formation of spores were not given in regular order. Circadian length of Neurospora decreased generally at the last cycle of the growth.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.201.3-201.3
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• 2003

The ethanol extract from the fruit of Terminalia chebula (Combretaceae) and the hook of Uncaria sinensis (Rubiaceae) exhibited significant inhibitory activity on oxidative stress and the age-dependent shortening of the telomeric DNA length. In the peroxidation model using t-BuOOH, human epidermal keratinocytes-neonatal foreskin (HEK-N/F) cells were treated with the T. chebula and U. sinensis extracts. The results showed a notable enhancing effect on the cell viability of 60.5 ${\pm}$ 3.8 and 65.0 ${\pm}$ 3.0%, respectively, by 50 $\mu\textrm{g}$/ml of the extracts. (omitted)

• 대한기계학회논문집A
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• 제34권9호
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• pp.1161-1166
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• 2010

테이퍼롤러 베어링은 축하중과 반경방향 하중이 동시에 인가되는 회전기계의 핵심 부품으로, 자동차 입력축과 출력축의 지지 베어링 등에 주로 사용되고 있다. 특히, 변속기에 사용되는 테이퍼롤러 베어링의 경우 조립시에 축방향 과다 예압이 인가된 상태로 조립된 경우 베어링의 수명이 단축되는 결과를 가져올 수 있다. 본 연구에서는 테이퍼롤러 베어링의 축방향 과다 예압에 의한 수명 단축 효과를 실험적으로 검증하고 그 결과에 의한 베어링의 수명 분포를 분석하였다. 또한, 기존의 $L_{10}$ 수명식에 비하여 현장 작동 조건에 따른 실질적인 수명을 산출할 수 있는 축방향과 반경방향을 고려한 수명식을 도출하고 이를 프로그램화 하여 설계 및 생산 현장에서 용이하게 활용할 수 있도록 하였다.

• 한국축산식품학회지
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• 제26권1호
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• pp.43-48
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• 2006

도압 후 오리 가슴육의 발골시간과 취급방법이 육질에 미치는 영향을 알아본 결과, 처리구 간의 pH는 유의적인 차이가 없었으나 냉동해동 처리구가 냉도체 발골구에 비해 높은 명도($L^*$)와 황색도($b^*$)를 나타내었을 뿐만 아니라 짧은 근절길이와 높은 가열감량을 보였고, 그 결과 높은 전단가를 나타내었다. 이 같은 결과는 냉동해동 처리구의 근원섬유 단백질 용해성이 낮은 것과 관련이 있었으며, 낮은 용해성은 nebulin과 같은 고분자 단백질이 사후초기에 냉동에 의해 분해되지 않은 결과로 사료된다. 따라서 오리고기는 도압 후곧바로 발골하여 냉동 또는 냉장 유통하는 것보다 냉도체 발골하여 냉장 유통하는 것이 육질향상을 위해 바람직할 것으로 사료된다.