• Journal of radiological science and technology
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• v.43 no.5
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• pp.389-395
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• 2020

The evaluation of radioactivated components of heavy-ion accelerator facilities affects the safety of radiation management and the exposure dose for workers. and this is an important issue when predicting the disposal cost of waste during maintenance and dismantling of accelerator facilities. In this study, the FLUKA code was used to simulate the proton treatment device nozzle and classify the radio-nuclides and total radioactivity generated by each component over a short period of time. The source term was evaluated using NIST reference beam data, and the neutron flux generated for each component was calculated using the evaluated beam data. Radioactive isotopes caused by generated neutrons were compared and evaluated using nuclide information from the International Radiation Protection Association and the Korea Radioisotope association. Most of the nuclides produced form of beta rays and electron capture, and short-lived nuclides dominated. However, In the case of ⁵⁴Mn, which is a radioactive product of iron, the effect of gamma rays should be considered. In the case of tritium generated from a material with a low atomic number, it is considered that handling care should be taken due to its long half-life.

• Wind and Structures
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• v.38 no.2
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• pp.147-160
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• 2024

The aerodynamic force is a significant component that influences the stability and safety of structures. It has unstable properties and depends on computer precision, making its long-term prediction challenging. Accurately estimating the aerodynamic traits of structures is critical for structural design and vibration control. This paper establishes an unsteady aerodynamic time series prediction model using Long Short-Term Memory (LSTM) network. The unsteady aerodynamic force under varied Reynolds number and angles of attack is predicted by the LSTM model. The input of the model is the aerodynamic coefficients of the 1 to n sample points and output is the aerodynamic coefficients of the n+1 sample point. The model is predicted by interpolation and extrapolation utilizing Unsteady Reynolds-average Navier-Stokes (URANS) simulation data of flow around a circular cylinder, square cylinder and airfoil. The results illustrate that the trajectories of the LSTM prediction results and URANS outcomes are largely consistent with time. The mean relative error between the forecast results and the original results is less than 6%. Therefore, our technique has a prospective application in unsteady aerodynamic force prediction of structures and can give technical assistance for engineering applications.

• Clinical Endoscopy
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• v.56 no.6
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• pp.726-734
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• 2023

Background/Aims: Endoscopic stenting for stricturing Crohn's disease (CD) is an emerging treatment that achieves more persistent dilatation of the stricture over time than endoscopic balloon dilatation (EBD). We aimed to explore the efficacy and safety of stenting for the treatment of CD strictures. Methods: A systematic electronic literature search was performed (PROSPERO; no. CRD42022308033). The primary outcomes were technical success, efficacy, complication rate, and the need for further interventions due to reobstruction. The outcomes of partially covered self-expanding metal stents (PCSEMS) with scheduled retrieval after seven days were also analyzed. Results: Eleven eligible studies were included in the review. Overall, 173 patients with CD were included in this study. Mean percentage of technical success was 95% (range, 80%-100%), short-term efficacy was 100% in all studies, and long-term efficacy was 56% (range, 25%-90%). In patients with a scheduled PCSEMS retrieval, the long-term efficacy was 76% (range, 59%-90%), the mean complication rate was 35% (range, 15%-57%), and the major complication rate was 11% (range, 0%-29%). Conclusions: Endoscopic stenting with scheduled PCSEMS retrieval may be considered a feasible second-line treatment for short CD strictures to postpone surgery. However, larger head-to-head prospective studies are needed to understand the role of stenting as an alternative or additional treatment to EBD in CD.

• Journal of Yeungnam Medical Science
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• v.20 no.2
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• pp.152-159
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• 2003

Background : Hyperlipidemia is the one of the major risk factors causing the atherosclerosis of coronary arteries. Treatment of hyperlipidemia with drugs has been confirmed the effects of therapy showing a decreased incidence of coronary artery disease. Simvastatin is a new drug of HMG-CoA reductase inhibitors and the short-term hypolipidemic effects and safety of simvastatin is evaluated in patients with hyperlipidemia. Methods: We studied 63 patients (39 males and 24 females, mean age 58) for 12 weeks whose plasma levels of total cholesterol were higher than 240 mg/dL or higher than 220 mg/dL with ischemic heart disease. Simvastatin was administered 20 mg/day and measured lipid profile at 12 week interval. Result: 1) Simvastatin significantly reduced the level of the plasma total cholesterol(-29.3%), LDL-cholesterol(-36.9%) and triglyceride(-13%)(p<0.05) but the level of HDL-cholesterol was not changed after 12 weeks simvastatin therapy. 2) the clinical symptoms and laboratory examination before and after simvastatin treatment showed no particular abnormal findings in short term follow up. Conclusion: These results suggested that short-term simvastatin therapy in patients with hyperlipidemia seeems to be very effective and safe.

• Food Science of Animal Resources
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• v.23 no.2
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• pp.137-144
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• 2003

This study was carried out to investigate safety evaluation of IGEs separated and refined from bovine milk and commercial recombinant human IGFs. In order to evaluate toxicity of these samples, acute toxicity test and short term toxicity test were investigated with IGF-I separated and refined from colostrum and commercial recombinant human IGF-I from R&D systems company. for acute toxicity test, we selected recombinant human IGF-I from R&D systems company and establish one control group and three dose-level groups(0, 10, 20 and 50 $\mu\textrm{g}$ per rat). We have intravenously injected tail of rats with selected sample once. After 20 days, pathological cellular tissue analyses were investigated with liver, kidney and spleen of 12 rats in all test groups. However, Morbid tissue and abnormal statistical results were not discovered in all cellular tissues. For short term toxicity test, we selected IGF-I separated and refined from colostrum and establish one control group and three dose-level groups(0, 5, 10 and 15 $\mu\textrm{g}$/day per rat). Rats were orally injected with selected sample once a day during two weeks. After short term toxicity test period, Pathological cellular tissue analyses were investigate with liver, kidney and spleen of 12 rats in all test groups. However, Morbid tissue and abnormal statistical results were not discovered in all cellular tissues. These results suggest that IGF-I treated groups show no significant toxicological findings with changes of body weight, food consumption, water consumption, and pathological findings compared with control groups.

• Journal of Positioning, Navigation, and Timing
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• v.13 no.2
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• pp.131-136
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• 2024

This paper deal with a method for calculating the continuity of Korea Augmentation Satellite System (KASS), which was completed in Korea in December 2023, and a plan to respond in the event that a continuity hazard situation occurs during operation. For this purpose, the International Civil Aviation Organization (ICAO) Satellite Based Augmentation System (SBAS) continuity standards, Wide Area Augmentation System (WAAS), and European Geostationary Navigation Overlay Service (EGNOS) continuity cases are examined in this paper. According to the measures recommended by the ICAO, when the number of continuity risks exceeds a certain level and the level drops drastically, various mitigation operations by country are implemented. Through this, if KASS does not meet ICAO continuity standards in the future, such measures can be referred to. In addition, this paper computes the short-term KASS continuity during the test broadcast period. Although continuity does not meet the ICAO standards, although this test period is too short, further meaningful analysis in the future is required. Additionally, this paper carried out an analysis of the timing and period to systematically calculate the meaningful value of continuity.

• Journal of Food Hygiene and Safety
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• v.12 no.3
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• pp.217-227
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• 1997

These experiments were performed to investigate the safety of the three medicinal herbs- Curcuma longa Linne, Paeonia japonica Miyabe, Scutellaria baikalensis George-irradiated with gamma rays in respect of genotoxicity. The methanol-soluble and water-soluble fractions of the methanol-water extracts of the 10 kGy gamma-irradiated herbs were examined in two short-term in vitro tests : (1) Salmonella typhimurium reversion assay (Ames test) in strain TA 98, TA 100 and TA 012 (2) Micronucleus test in cultured Chinese hamster ovary (CHO) cells. No mutagenicity was detected in the assays with or without metabolic activation. From these results, the safety of the herbs irradiated with gamma rays at practical doses could be revealed in further tests of genotoxicity in vivo, chronic and reproductive toxiceity.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.22 no.3
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• pp.73-87
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• 2023

Furnishing traffic safety information can contribute to providing hazard warnings to drivers, thereby avoiding crashes. A smart road lighting platform that instantly recognizes road conditions using various sensors and provides appropriate traffic safety information has therefore been developed. This study analyzes the short-term traffic safety improvement effects of the smart road lighting's tunnel traffic safety information service using surrogate safety measures (SSM). Individual driving behavior was investigated by applying the vehicle trajectory data collected with RADAR in the Anin Avalanche 1 and 2 tunnel sections in Gangneung. Comparing accumulated speeding, speed variation, time-to-collision, and deceleration rate to avoid the crash before and after providing traffic safety information, all SSMs showed significant improvement, indicating that the tunnel traffic safety information service is beneficial in improving traffic safety. Analyzing potential crash risk in the subdivided tunnel and access road sections revealed that providing traffic safety information reduced the probability of traffic accidents in most segments. The results of this study will be valuable for analyzing the short-term quantitative effects of traffic safety information services.

• Journal of the Korean Society of Safety
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• v.23 no.6
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• pp.150-157
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• 2008

The purpose of this study was to investigate the effect of short-tenn stretching type of muscular strength gymnastics on health-related fitness and rating of perceived pain for automotive industry workers. The subjects selected were 27, who were divided into 3 groups(A group=10, B group=9, C group=8). Group A performed a short-term stretching Type of Muscular Strength Gymnastics only one time. Group B continuously performed the exercise program two times. Group C was a control group. The exercise program was a stretching Type of Muscular Strength Gymnastics, which was performed 3 times per week for 4 weeks. Its intensity was RPE 11-15. Data analysis was conducted by using SPSS ver 14.0. The test was conducted with two-way repeated ANOVA, post-hoc Ducan and paired t-test (a<.05). This study showed the following results. Muscular strength, muscular endurance and flexibility increased in all intra and between groups. Ratio of %fat decreased for group B but the control group presented conversely. Rating of perceived pain of group A decreased at arm and hands. Rating of perceived pain of group A decreased at back and leg.

• Journal of Gastric Cancer
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• v.15 no.4
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• pp.231-237
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• 2015

Purpose: Various laparoscopic wedge resection (LWR) techniques requiring gastrotomy for gastrointestinal stromal tumors (GISTs) of the stomach have been applied to facilitate tumor resection and preserve the remnant gastric volume. However, there is the possibility of cancer cell dissemination during these procedures. The aim of this study was to assess the oncologic safety of LWR with gastrotomy (LWR-G) compared to LWR without luminal exposure. Materials and Methods: Clinicopathologic and operative results of 193 patients who underwent LWR for gastric GIST were retrospectively analyzed from 2003 to 2013. We stratified the patients into two groups: LWR-G and LWR without gastrotomy (LWR-C). Clinicopathologic features, short-term outcomes, and long-term outcomes were compared. Results: A total of 26 patients underwent LWR-G, and 167 patients underwent LWR-C. The LWR-G group showed significantly more anterior wall-located (n=10, 38.5%), intraluminal (n=20, 76.9%), and ulcerative (n=13, 50.0%) tumors than the LWR-C group (n=33, 19.8%; n=96, 57.5%; n=46, 27.5%, respectively). Postoperative short-term outcomes did not differ between the two groups. When tumor staging was compared, no statistical difference was noted. There was no recurrence in the LWR-G group, while 2 patients in the LWR-C group experienced recurrence. The two recurrences in the LWR-C group were found in the liver and in the remnant stomach at 63 and 12 months after the operation, respectively. No gastric GIST-related death was recorded in any group during the study period. Conclusions: LWR-G for gastric GIST is an oncologically safe procedure even for masses with ulcerations.