• 동의생리병리학회지
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• 제19권2호
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• pp.530-535
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• 2005

A Korean traditional herbal formular, Taeumbiman-tang(TBT), was based on Taeumjowi-tang, currently the most widely used herbal formula compound, and which is known to be safe and have a positive effect on adult obesity. TBT was given to obese children for thirty days, and was found to be clinically safe and effective. The subjects were children who had been admitted into the hospital to be treated for obesity, that had more than 20% relative body weight. Originally there were 19 subjects, but 5 dropped out of the experiment. There were 5 girls and 9 boys, whose average ages were $11.00\;{\pm}\;2.60$ years, average weight was $54.01\;{\pm}\;18.59\;kg$. As a pretest, all of the volunteers were examined for height, weight, blood pressure, pulse rate, EKG, and chest radiography. The subjects underwent interview, body measurement tests, blood tests, and safety tests under 8 hour fasting state. After 15 days of TBT intake, the safety tests and the interview were conducted. The interview, body measurement tests, blood tests, and safety tests were conducted again after the 30 day trial was completed. The short term effects of TBT on obese children is weight loss. It did not cause any significant changes in the subject's livers, hearts, and kidneys, and clinically dangerous side effects or withdrawal symptoms were not observed.

• Journal of Preventive Medicine and Public Health
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• 제22권3호
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• pp.380-388
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• 1989

To evaluate the costs of the hypertension screening program of the Korea Medical Insurance Corporation, the records of the screening examinations were used. The sample size was 49,983 of the 906,554 people insured by the Corporation and was obtained by two-stage stratification random sampling. The alternatives for efficiency of the screening program, which were divided into three categories : modification of the screening test package, application of other hypertension diagnostic criteria, and selective approach of tested groups by age, were evaluated according to the cost per patient detected. The results of this study were as follows In the hypertension screening system, the cost per patient detected was Won 30,883. The most nonsensitive test for hypertension detection was ophthalmoscopy, which was examined during the second stage of screening. If the ophthalmoscope examination was excluded, olny one person was not detected, which was 0.2% of detected persons, and the cost per patient detected decreased to Won 28,098. The most efficient modification of the screening test package was measurement of blood pressure through the first and second stages of screening. The cost per patient detected by this modification was Won 24,408. The application of other diagnostic critera, which were more restricted criteria, increased the cost per patient detected by 3.7%-6.7%. The cost per patient detected were Won 170,582 for persons less than 39 years old, Won 20,032 for persons 40 to 59 years old, and Won 8,675 for persons 60 years old and over. In conclusion, the best alternative suggested with respect to efficiency and practical application excluded the ophthalmoscope examination of second stage screening and restricted the target population to persons greater than 40 years old. The application of this alternative decreased 54.9% of the screening costs and the cost per patient detected was Won 15,222. This study was limited in that measurement of effectivenes was not of the ultimate goal of screening, which is decreasing morbidity and mortality, but was of disease detection as the short-term objective.

• 한국산업보건학회지
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• 제29권3호
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• pp.336-342
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• 2019

Introduction: An unexpected death was reported in a beginner immediately after starting the work at a plating factory. After the incident, air sampling was performed using a simulation of the situation as it had been at the time. Methods: To evaluate the airborne concentration of hydrogen cyanide, a total of six samples were collected: one personal sample, three area samples, and two background samples (office and outdoors). Hydrogen cyanide measurement was performed according to the standard sampling protocol recommended by the U.S. NIOSH (National Institute of Occupational Safety and Health). Results: The highest concentration of hydrogen cyanide was 0.938 ppm measured in a sample collected from the plating bath area with local exhaust ventilation. This value was approximately 20% of the ceiling occupational exposure limit. The personal sample showed a concentration of 0.135 ppm. Samples collected near the bath in which the incident occurred and a dehydrator showed hydrogen cyanide concentrations of 0.236 ppm and 0.101 ppm, respectively. Hydrogen cyanide was not detected in the background samples (office and outdoors). Conclusions: It is necessary to use proper ventilation systems and respirators in plating factories to prevent acute poisoning. Furthermore, it is important to educate and train new workers dealing with toxic substances.

• 대한한방소아과학회지
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• 제18권1호
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• pp.77-91
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• 2004

Objective: The purpose of this study were to examine the growth pattern of weak children by measurement according to the five weak symptoms (respiratory, digestive, psycho-neurological, neuromotor, urogenital symptom). Five weak symptoms are common etiology of short stature in childhood and oriental medicine therapy is used as a treatment in short stature but the effects on height are not conclusive. Methods: This clinical study had been carried out with the 166 case (male 74, female 92) of the children aged 3 to 18 years old who visited in growth clinic of Pediatrics, Dongguk university Bundang Oriental Hospital. They were divided into 3 groups by age (3-10, 11-14, 15-18 years group) Five weak symptoms were studied to determine the association with growth stature among children by comparison with the growth stature of weak children group and normal group Results: The distribution of age showed the highest in 11-14 years(58.4%), followed by I 3-10 years (26.5%), over 15years(15%) in order. In case of male, the distribution of five weak symptoms showed the highest respiratory weak symptom(68.9%), followed by digestive(52.7%), psycho-neurological(43.2%), neuromotor(24.3%), urogenital weak symptom (143.5%) and digestive weak children's Height SDS were lower than normal children in all age groups and respiratory weak children's Height SDS were lower than normal children in age group of 3-10. In case of female, the distribution of five weak symptoms showed the highest digestive weak symptom(59.8%), followed by respiratory(52.5%), psycho-neurological(51.5%), neuromotor (35.9%), urogenital weak symptom (25%) and digestive weak children's Height SDS were lower than normal children in age group of 3-14. Other weak children Height SDS were no significant difference from normal group. Conclusions: From the above result, it was suggested that weak symptoms is cause in short stature. These data indicate that the height was correlated with respiratory, digestive weak symptom and a way to improve the weakness increased significantly height in children growth stature. Growth stature should be investigated as a new field of oriental medical treatment and more controlled, long term studies are required to classify benefits of Oriental medicine therapy in short stature.

• 한국해안해양공학회지
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• 제14권1호
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• pp.51-64
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• 2002

협수로로 연결된 속초항과 청초호의 장주기파 공진을 검토하기 위하여 항내·외 8개 정점에서 파향·파고계, 초음파식 파고계, 수압식 파고계, 유속계 등을 이용하여 장·단주기파 현장관측을 실시하였다 자료 분석 결과 속초항과 청초호의 Helmholtz 공진 모드의 주기는 각각 13.6분과 54.5분으로 제시되었으며, 협수로 내 주된 유속의 출현 주기는 55.2분으로 청초호의 Helmholtz 공진 조건에 지배됨을 알 수 있었다. 저중력파로 인한 국부 부진동의 에너지 수준은 평상시보다 폭풍시에 훨씬 더 큰 것으로 나타났다. 항내·외 정점에서의 저중력파 파고와 항외의 단주기파고에 대한 회귀분석 결과 양자는 거의 선형적인 상관 관계를 가지는 것으로 나타났다. 그러나 양자의 주기들, 단주기 파향과 저중력파 파고, 단주기 파고와 저중력파 주기 사이에는 특별한 상관 관계를 발견하지 못하였다. 한편, 향후 장기간 자료가 축적되면 속초항 해역에서의 저중력파 파고에 대한 극치 해석을 통하여 재현빈도별 저중력파 파고를 추정할 수 있을 것으로 사료되었다.

• 대한한방내과학회지
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• 제28권1호
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• pp.106-114
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• 2007

Background : Mahuang (Ephedrae Herba, Ephedra sinica $S_{TAPE}$) has been widely used to treat respiratory disease in Asian over the past thousand years. The main ingredient of Mahuang is ephedrine, whose affects on the autonomic nervous system induce some adverse effects like vasoconstriction, hypertension, tachycardia, miosis, insomnia, dizziness, headache, etc. Although there were lots of reports about adverse effects of Mahuang, there were no clinical studies which evaluated the adverse effects of Mahuang on the autonomic nervous system by objective numerical value in the past decade. Objectives : The purpose of this report was to provide an objective assessment of state-trait anxiety that is caused by Mahuang, and to identify anxiety of Mahuang according to different Sasang constitution classifications. Methods : The study design was a double-blind randomized placebo-controlled trial. The subjects of this study were 79 adults aged between 20 to 40 who agreed to participate. Because 8 adults dropped out, a total of 71 subjects entered the study. They were allocated through randomization to a Mahuang group (N=50) and placebo group (N=21). Each group took three opaque capsules (every opaque capsule containing 2g of Mahuang or none) twice a day. To compare the state and trait anxiety before and after taking Mahuang, we checked the anxiety by using STAI-KYZ. Results : The following results were obtained. Short-term administration of Mahuang significantly increased state-anxiety, but in the placebo group, there were no significant changes in state-anxiety. In the Mahuang group except females, there was more significant increase in state-anxiety of Soeumin than Soyangin and Taeumin in the 2nd measurement. Conclusion : It is suggested that the ingestion of Mahuang can increase sympathetic activity and induce anxiety. There was a significant difference among Sasang constitution classification. Especially, the response is stronger in Soeumin than other constitutions. If we use Mahuang according to the Sasang constitution classification in clinic, we could not only minimize the anxiety but maximize the potential curative value.

• 대한원격탐사학회지
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• 제39권5_4호
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• pp.1125-1134
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• 2023

우리나라의 17,000여개의 저수지 중 13,600개소의 소규모 농업용 저수지에는 수문 계측 시설이 설치되지 않아서, 저수율 예측과 합리적인 저수지 운영이 쉽지 않다. 본 연구는 인공지능 기술을 이용하여 농업용 저수지의 저수율을 예측하는 것을 목적으로 하며, 단변량 long short-term memory (LSTM)에서 저수율 그 자체를 사용하는 것뿐만 아니라, 다변량 LSTM에서 강수 등의 기상변수와 시기 등의 계절변수를 추가하여 예측에 활용하였다. 이동저수지의 2013년부터 2020년까지 8년간 데이터로 모델을 학습시키고, 모델의 예측 결과를 2021년의 일일 저수율 데이터로 검증하였다. 단변량 LSTM은 1일 후 저수율을 root-mean square error (RMSE) 1.04%, 3일 후 2.52% 이내, 5일 후 4.18%의 오차로 예측하였으며, 다변량 LSTM은 1일 후 저수율을 RMSE 0.98%, 3일 후 1.95%, 5일 후 2.76%의 오차로 예측하여 더 좋은 성능을 보였다. 1일 후 저수율을 예측하는 다변량 모델의 경우, 시계열 저수율 이외에도 date of year (DOY)와 1일 및 5일 누적 강수량이 중요한 변수인 것으로 나타났는데, 이를 통해 볼 때 당일 저수율에 영향을 미치는 강수의 시간적 범위는 5일 정도인 것으로 사료된다.

• 생물환경조절학회지
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• 제8권3호
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• pp.192-201
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• 1999

본 연구는 ASKAM모델로 $CO_2$, 광 및 엽면적지수가 단고추의 동적 광합성율에 추정가능성을 평가하기 위하여 수행되었다 $CO_2$ 농도는 2구획으로 구분된 반밀폐된 생장상에서 3수준 (400, 700 or 1000$\mu$mo1 mol$^{-1}$)으로 조절하였다. 온도와 습도는 21$^{\circ}C$ 및 80-95%로 조절하였고, 양액이 순환되는 용기내에서 재배하였다. 일태양복사, 온도 및 $CO_2$농도의 단기 자료를 기초로 하여 일중 단기간격에 대한 작물 순$CO_2$흡수량를 ASKAM모델로 추정하였고, 광합성 측정 중 각 구획과 기부에서의 $CO_2$농도를 매분마다 측정하였다. 순수 $CO_2$의 구획으로의 흐름, 지상방사, 구획내의 광합성유효방사, 은도 및 상대습도를 측정하였다. 본 작물생장모델은 작물의 광합성율을 적절하게 추정할 수 있는 것으로 평가되므로 생장해석, 작물관리 및 온실관리에 광범위하게 적용될 수 있을 것으로 판단되었다.

• 전자공학회논문지SC
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• 제41권1호
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• pp.1-8
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• 2004

INS는 위치, 속도 및 자세정보를 고속으로 제공하며 스스로 항법정보를 제공하는 장점이 있으나 오차가 시간에 따라 증가하는 단점이 있다. 반면에 GPS는 데이터를 저속으로 제공하며 재밍(Jamming)에 영향을 쉽게 받으나 오차가 시간에 상관없이 일정하다는 장점이 있다. 따라서 상호보완적인 특성을 가지는 INS와 GPS를 통합하였을 때 더욱더 정확한 항법해를 제공할 수 있다. 그러나 INS와 GPS를 통합하는 과정에서 INS정보와 GPS정보의 정확한 시각적 동기가 어려우며, 시각적 비동기에 의한 오차는 일정한 측정오차를 유발하며 고속으로 운항하는 경우에는 큰 영향을 미치게 된다. 본 연구는 GPS/INS 통합항법 시스템에서 측정치 시간지연에 의해 유발되는 오차를 효과적으로 줄이기 위해 바이어스 분리형 칼만필터를 이용한 시간지연오차 보상기법을 강결합 방식과 약결합 방식에 대하여 각각 제안하였다. 각각의 통합모델에서 위치와 속도보정의 측정방정식을 지연시간에 관하여 선형화하였고 지연 상태변수를 기존의 선형 오차방정식에 추가하고 바이어스 분리형 칼만필터를 적용하여 시간지연을 초기에 추정하여 보상하도록 구성하였으며 시뮬레이션을 통하여 성능을 검증하였다.

• 대한한방부인과학회지
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• 제23권1호
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• pp.42-52
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• 2010

Purpose: This report aims to administer methodologic issues around recently conducted multicenter study for evaluating the effects of acupuncture on menopusal hot flashes and discuss practical issues for further implementation of acupuncture clinical trial for hot flashes. Methods: Study process were mentioned, and issues related to avoiding risk of bias, designing appropriate control group, optimal outcome measurement, potential different effects of menopausal status on study outcomes, and suggestions for developing future clinical trials are discussed. Results: Shortcomings of our multicenter study include lack of allocation concealment and assessor blinding, subjective outcome measurement, short-term follow-up, and fixed acupuncture regimen despite pragmatic purpose of this study. Improving trial design, using objective or validated outcomes, assessing long-term effects of acupuncture, and individualizing acupuncture regimen are needed in future clinical trials. Conclusion: We expect these practical discussions to enable researchers to plan and develop future well-designed clinical trials for evaluating the effects of acupuncture on hot flashes or other women's health issues.