• 한국어병학회지
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• 제37권1호
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• pp.123-132
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• 2024

Viral diseases cause enormous economic losses to the olive flounder (Paralichthys olivaceus) aquaculture industry in Korea. This study aimed to identify immune-related genes expressed in the kidney of olive flounder injected with Polyinosinic-polycytidylic acid (Poly (I:C)). Thirty fish were divided into two groups by intraperitoneal injection of 100µl of diethylpyrocarbonate-treated water or poly I:C per fish. Kidney tissues at day 3 and 30 after the injection were used for RNA-seq analysis to identify differentially expressed genes (DEGs). Poly I:C group upregulated il8, cfh, tnfaip2b, c3b.2, ly6d and cd38 genes at 3 days post-injection. Additionally, cd22, ccl34a.3, c9, cxcl19, ccl27a, ccl7, and cfh genes were upregulated at 30 days post-injection. Differential expression gene analysis showed that poly I:C has both short and long-term immune effects in olive flounder. This study provides a theoretical basis for understanding the molecular mechanism of the short and long-term immune effects of poly I:C.

• 한국자동차공학회논문집
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• 제9권6호
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• pp.16-23
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• 2001

Spray dispersion in high pressure diesel engines have been simulated experimentally with a special emphasis on the effect of swirl by using a liquid injection technique. A constant volume chamber was designed to be rotatable in order to generate a continuous swirl and to have the flow field closely resembling a solid body rotation. Emulsified fuel was injected into the chamber and the developing process of fuel sprays was visualized. The effect of swirl on the spray dispersion was quantified by calculating non-dimensionalized dispersion area according to the spray tip penetration length. The results show that the effect of swirl on the spray dispersion is different between short and long spray penetrations. For short range of spray tip penetration, the effect of swirl on spray dispersion is quite small. However, as the spray tip is penetrated into longer distance in spray chamber, the effect of swirl on spray dispersion becomes larger. These results can be used as a basic data for designing combustion chamber and injection system of direct injection diesel engine.

• Nuclear Engineering and Technology
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• 제47권6호
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• pp.719-728
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• 2015

Following the Fukushima accident, a special safety inspection was conducted in Korea. The inspection results show that Korean nuclear power plants have no imminent risk for expected maximum potential earthquake or coastal flooding. However long- and short-term safety improvements do need to be implemented. One of the measures to increase the mitigation capability during a prolonged station blackout (SBO) accident is installing injection flow paths to provide emergency cooling water of external sources using fire engines to the steam generators or reactor cooling systems. This paper illustrates an evaluation of the effectiveness of external cooling water injection strategies using fire trucks during a potential extended SBO accident in a 1,000 MWe pressurized water reactor. With regard to the effectiveness of external cooling water injection strategies using fire engines, the strategies are judged to be very feasible for a long-term SBO, but are not likely to be effective for a short-term SBO.

• 한국정밀공학회지
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• 제19권12호
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• pp.33-37
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• 2002

A short shot is a molded part that is incomplete because insufficient material was injected into the mold. Remedial actions to control the process conditions can be taken by the injection molding experts based on their knowledge and experience. However, it is very difficult for the non-experts to avoid short shot by finding the proper process conditions such as mold temperature, melt temperature and filling time. In this paper, an intelligent generator of the optimal process conditions based upon fuzzy logic algorithm is proposed so that trial and error can be minimized and the non-experts as well as the experts can also find the optimal process conditions.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2001년도 춘계학술대회 논문집
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• pp.402-405
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• 2001

A short shot is a molded part that is incomplete because insufficient material was injected into the mold. Remedial actions to control the process conditions can be taken by the injection molding experts based on their knowledge and experience. However, it is very difficult for the non-experts to avoid short shot by finding the proper process conditions such as mold temperature, melt temperature and filling time. In this paper, an intelligent generator of the optimal process conditions based upon fuzzy logic algorithm is proposed so that trial and error can be minimized and the non-experts as well as the experts can also find the optimal process conditions.

• 한국산학기술학회논문지
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• 제3권1호
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• pp.1-4
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• 2002

사출성형에서 제품의 최종 품질에 영향을 미치는 중요한 인자들 중의 하나는 사출압력이다. 전통적으로 현장의 사출전문가는 오래된 현장 경험을 바탕으로 사출압력을 결정한다. 그러나 비전문가에게는 제품의 크기, 형상 그리고 사출공정의 전반적인 과정을 고려한 적절한 사출압을 결정하기가 쉽지 않다. 본 연구에서는 퍼지 논리(fuzzy logic)를 이용하여 제품도면에 나와 있는 제품두께와 유동길이를 알면 쉽게 초기 사출압을 결정할 수 있도록 전문가의 경험을 규칙베이스화 하였다. 규칙베이스를 구성하기 위해서 현장 전문가들을 인터뷰하고 설문조사를 한 후 기술적인 문서를 작성하여야 하지만 본 연구에서는 사출성형 해석 프로그램인 C-Mold를 이용하여 수 차례의 시뮬레이션을 반복 수행하여 규칙베이스를 구성하였다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1997년도 추계학술대회 논문집
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• pp.97-100
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• 1997

In order to predict the moldability of a injection molded part, a simulation of filling is needed. Especially when short shot is predicted by CAE simulation in the filling stage, there are mainly three ways to solve the problem. Modification of gate and runner, replacement of plastic resin, and adjustment of process conditions are the main ways. Among them, adjustment of process conditions is the most economic way in the cost and time since the mold doesn\\`t need t be modified at all. But it is difficult to adjust the process conditions appropriately in no times since it requires an empirical knowledge of injection molding. In this paper, a fuzzy neural network(FNN) based upon injection molding process is proposed to evaluate moldability in filling stage and also to solve the problem in case of short shot. An adequate mold temperature is generated through the fuzzy neural network where fill time and melt temperature are taken into considerations because process conditions affect each other.

• Journal of Veterinary Science
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• 제24권3호
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• pp.43.1-43.8
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• 2023

Background: Meloxicam is used widely for exotic animal analgesia, but its toxicity in common raptor species in Thailand is unclear. Objectives: This study evaluated the single-dose effect of intramuscular meloxicam in common raptor species in Thailand for short-term and long-term periods. Methods: Twenty-two raptors were administered a single 1 mg/kg dose of meloxicam individually via intramuscular injection. The following were evaluated: clinical appearance, body weight, body condition score, body temperature, fecal appearance, complete blood cell count, and biochemistry panel before (day 0) and after the injection (1, 7, and 30 days). The collected samples were categorized into three groups: Brahminy kite (Haliastur indus) (n = 10), adult Barn owl (Tyto javanica) (n = 4), and juvenile Barn owl (n = 8). Results: None of the raptors in the study groups showed any abnormalities. The hematological profiles were significantly different in the short-term period (day 1 and day 7). The creatinine, aspartate aminotransferase, and creatinine kinase increased in several groups. On the other hand, the packed cell volume decreased in the Brahminy kite and juvenile Barn owl groups. According to the findings, an intramuscular injection of 1 mg/kg meloxicam affected the blood biochemistry panel of the muscle, but the affected raptors recovered within one week. Conclusions: An intramuscular injection of meloxicam at a single 1 mg/kg dose in Brahminy kites and Barn owls was not associated with the morbidity, hepatotoxicity, gastrointestinal toxicity, and nephrotoxicity in the short- and long-term periods.

• 소성∙가공
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• 제12권2호
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• pp.134-140
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• 2003

Polymers such as polypropylene or polyethylene offer a unique feature of producing an integral hinge, which can flex over a million times without causing a failure. With such advantage manufacturing, time and cost required at the assembly stage can be eliminated by injecting the whole part as one piece. However, due to increased fluidity resistance at hinges during molding, several defects such as short shot or premature hinge failure can occur with the improper selection of gate locations. Therefore, it is necessary to optimize flow balancer in injection molding of part with hinges before actually producing molds. In this paper, resin flow patterns depending on several gate positions were investigated by numerical analyses of a simple strip part with a hinge. As a result, we found that the properly determined gate location leads to better resin flow and shorter hesitation time. Finally, injection molding tryouts using a mold that was designed one of the proposed gate systems were conducted using polypropylene that contained 20% talc. The experiment showed that hinges without defects could be produced by using the designed gate location.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2001년도 춘계학술발표대회 논문집
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• pp.201-204
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• 2001

A Confocal Laser Scanning Microscope (CLSM) is applied to determine three-dimensional fiber orientation states in injection-molded short fiber composites. Since the CLSM optically sections the composites, more than two planes either on or below the surface of composites can be obtained. Therefore, three dimensional fiber orientation states are determined without destruction. To predict the orientation states, velocity and temperature fields are calculated by using a hybrid FEM/FDM method. The change of orientation state during packing stage is also considered by employing a compressible Hele-Shaw model. The predicted orientation states show good agreement with measured ones. However, some differences are found at the end of cavity. They may result from other effects, which are not considered in the numerical analysis.