• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.17 no.1
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• pp.31-36
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• 2014

Purpose: Infliximab (IFX) is considered safe and effective for the treatment of ulcerative colitis (UC) in both adults and children. The aim of this study was to evaluate the short- and long-term clinical course of IFX in Korean children with UC. Methods: Pediatric patients with UC who had received IFX infusions between November 2007 and May 2013 at Samsung Medical Center were retrospectively investigated. The clinical efficacy of IFX treatment was evaluated at 8 weeks (short term) and 54 weeks (long term) after the initiation of IFX treatment using the Pediatric Ulcerative Colitis Activity Index (PUCAI). The degree of response to IFX treatment was defined as complete response (PUCAI score=0), partial response (decrement of PUCAI score${\geq}20$ points), and non-response (decrement of PUCAI score <20 points). Adverse events associated with IFX treatment were also investigated. Results: Eleven pediatric patients with moderate to severe UC had received IFX. The remission rate after IFX treatment was 46% (5/11) and 82% (9/11) at 8 weeks and 54 weeks after IFX treatment, respectively. All patients who were steroid-dependent before treatment with IFX achieved remission at 54 weeks and were able to stop treatment with corticosteroids, while all steroid-refractory patients failed to achieve remission at 54 weeks after treatment with IFX. Conclusion: Response to IFX treatment after 8 weeks may predict a favorable long-term response to IFX treatment in Korean pediatric UC patients.

• Journal of Preventive Medicine and Public Health
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• v.28 no.2 s.50
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• pp.487-496
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• 1995

This study was performed for the comparison of the therapeutic efficiency between 6-month (2HERZ/4HER) and 9-month (9HER) short-course chemotherapy under the programe conditions for pulmonary tuberculosis in terms of sputum AFB negative conversion rate, remedial interruption rate and cost effectiveness analysis. Two hundreds and ninty three patients treated with 9HER and 641 treated with 2HERZ/4HER had been discharged from 22 health centers in Seoul from May 1, 1993 to April 30, 1994. Seven hundreds and seventeen was subsequently analysed excluding 217 patients due to remedial interruption. The results : 1. Bacteriological negative conversion rate in 9HER regimen and 2HERZ/4HER regimen was 97.8% and 96.4% respectively(p>0.05). But the early treatment period, negative conversion rate in 2HERZ/4HER regimen was very higher than in 9HER regimen(p<0.01). 2. Remedial interruption rate for 9HER regimen and 2HERZ/4HER regimen was 34.1% and 13.6% respectively. The primary reason for the interruption was transfering to other clinics and this interruption was high within 3months. 3. Cost effectiveness for 2HERZ/4HER regimen was higher than 9HER regimen. The difference cost effectiveness ratio was 2.33 at the first sputum test and 1.69 at the last sputum test.

• Tuberculosis and Respiratory Diseases
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• v.70 no.3
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• pp.191-198
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• 2011

Ventilator-associated pneumonia (VAP) is the most frequent nosocomial infection in the intensive care unit (ICU), with an incidence ranging from 8% to 38%. Patients who acquire VAP have higher mortality rates and longer ICU and hospital stays. Because there are other potential causes of fever, leukocytosis, and pulmonary infiltrates, clinical diagnosis of VAP is overly sensitive. The only alternative approach to the clinical diagnosis of VAP is the Clinical Pulmonary Infection Score (CPIS). Employing quantitative cultures of respiratory secretions in the diagnosis of VAP leads to less antibiotic use and probably to lower mortality. With respect to microbiologic diagnosis, however, it is not clear that the use of invasive sampling using bronchoscopy is associated with better outcomes. Delayed administration of antibiotic therapy is associated with an increased mortality, and inadequate antibiotic therapy is also associated with higher mortality. Therefore, prompt initiation of adequate antibiotic therapy is a cornerstone of the treatment of VAP. The initial antibiotic therapy should be based on the most common organisms in each hospital and the most likely pathogens for that specific patient. When final cultures and susceptibilities are available, de-escalation to less broad spectrum antibiotics should be done. Since clinical improvement usually takes 2 to 3 days, clinical responses to the initial empirical therapy should be evaluated by day 3. A short course of antibiotic therapy appears to be equivalent to a traditional course of more than 14 days, except when treating non-fermenting gram-negative organisms. If patients receive initially adequate antibiotic therapy, efforts should be made to shorten the duration of therapy to as short as 7 days, provided that the etiologic pathogen is not a non-fermenting gram-negative organism.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.12
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• pp.309-315
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• 2020

This study examines the accounting students' level of moral development at the university. In this study, we focused on the effects of ethics subject and gender on moral development. Therefore, we compare the moral development of male and female students. We evaluated 216 students in Cognitive Moral Development (CMD) from 17 universities in Indonesia. We measured CMD with the Defining Issues Test (DIT) model developed by Rest in 1986. The findings show that there is no difference in DIT scores between students who have taken the ethics subject and who have not taken. We also confirm female students have a higher DIT score than male students. Our study results show that gender plays an important role in the ethics issue. Our study strengthens the previous research about the effect of ethics study and ethics courses on CMD. This study has an implication for ethics education in university wherein the curriculum or the system should be prepared carefully. Although the results of this study did not show that ethics subject has a strong impact on students' CMD, we still believe that the ethics course plays a significant role in the accountants' morals. For that reason, we argue that morals need time to be developed, and cannot be taught in a short-term course. Future research is needed to explore more about this issue.

• Korean Institute of Interior Design Journal
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• no.20
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• pp.17-25
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• 1999

The curriculum analysis of lighting design course in the Interior architecture departments in American universities reveals they share a major concern in the basic lighting theories, the sorts of light source and lighting equipment, daylighting, and interior lighting plav. The curriculum is usually composed of two semesters, the first semester being about lighting theory and simple project, while the second one abut more professional fields of design studio. The curriculum of lighting design at the Interior architecture departments in Korean colleges and universities usually consists of introductory courses in the field. Almost every institution allocated only one semester for the courses, and as the courses should cover the broad range within a short time, they were lacked in the required depth and systematic approach. The analysis also reveals the curriculum in Korea puts emphasis on the interior lighting equipment design, while disregarding the importance of daylighting. In comparison, American institutions have their curriculum focused upon the use of daylighting. The curriculum of lighting design courses in Korea, a major part of space rendering methods in the field of Interior Architecture, should be improved without delay. The courses should be included in the required subjects and the educational aims should be changed from offering a general understanding of the concepts to providing professional knowledge and skills, which would contribute to the competitiveness of the departments.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.4
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• pp.1067-1073
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• 2008

This study grasped the problem by examining the consciousness of professors about the e-Learning and reached a conclusion as follows. The understanding of the e-Learning in university should be reconsidered and diffused. To activate the e-Learning in university, the education system corresponding to course of the coming education should be introduced by hold the seminar and workshop periodically and establish vision and middle-short range policy for the e-Learning. Also, university should manage by characterizing a web-based class with the major for a learner hoping to take a cyber education course and propel contents development and interchange with a foreign university by concluding a convention for taking lectures having competitive power of an advanced country to make a worldwide university.

• Journal of Korean Library and Information Science Society
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• v.14
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• pp.181-215
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• 1987

Reading education is very important in order to promote the refinement, cultivate the emotion and complete the character to the secondary school students. This thesis deals with the establishment of reading education as a formal course in secondary schools, responsibility of teaching and problems related to recommended reading lists. Reading education must separate from the national language education because of literature centered education in reading education. If reading education was separated from the national language education, students can a n.0, pproach to the other cultural boundary besides other own and exchange their information and ideas. So, reading education must be included to the elective subjects in a independent course or become a compulsory subject in secondary school curriculum. The teacher of reading education must become the teacher librarian who has a firm faith and an intellectual accomplishment. But, teacher-librarian has much disadvantages such as the problems of promotion, the division of qualification between elementary school and secondary school, and a short-term training courses for teacher-librarian. Hence, theses problems music be solved in national administrative level. Recommended reading lists must be provided to the student in order to prevent confusion of the sense of value, to estimate their own reading ability by themselves and to establish life long reading plan. Therefore, both Korean Library Association and the Ministry of Education should re-examine and develop recommended reading lists. Finally, problems of a juvenile delinquency in the post industrial society have to be solved through reading education. To solve the juvenile delinquency problems, adolescents should cultivate their moral character and possesses abundant knowledge through reading education. Then, young adults will grow as sound citizen in the society.

• Journal of the Korean Institute of Landscape Architecture
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• v.29 no.5
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• pp.84-91
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• 2001

The purpose of this thesis is to search for appropriate design elements to manage ponds on golf courses. This paper showed that a variable, width, and volume have significant influence on satisfaction(Sig 0.001). This research investgated golf courses in Kyung-ki province. In short, we measured the physical design elements of ponds to bring out major factors which could determine satisfaction of golf courses for golfcourse manager(greenkeeper). The results between satisfaction and physical variable came out as follows; 1, Golfcourse managers(Green keepers) responded to questions that they were satisfied in only 29.9% of the ponds. We found that they considered management very highly. we could evaluated the value of necessity and importance are high, that is importance to manage ponds 2. Some physical design elements(volume, width) increased dependent variable(satisfaction) and others(length, area, circumference, index of shape) decreased dependent variable(satisfaction) 3. Volume has an influence on dependent variable more than depth on index of shape. 4 If the result of \`index of shape\` decreased, the result of \`management satisfaction\` would be high, and when volume is 8500ton∼17000ton, depth is 27m∼3.1m, \`management satisfaction\` would be high. The research findings can be used for planning and designing of golfcourses for designers, and by management for greenkeepers, and will provide pertinent design elements far design of golfcourses. We suggest that the interrelation between ponds and strategic play must be examined in future research.

• Journal of Advanced Marine Engineering and Technology
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• v.39 no.1
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• pp.81-85
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• 2015

The organic/inorganic hybrid photovoltaic devices have been studied using Poly(3-hexylthiophene-2,5-diyl) (P3HT) : [6, 6]-Phenyl C61 butyric acid methyl ester (PCBM) and GaN. We traced the effect of short circuit current density with different annealing method under the various concentration and ratio of P3HT:PCBM. During the pre-annealing course, the heat treatments were performed each time at low temperature after the organic layer coated and the samples were heated at high temperature through one or two steps under the post-annealing process. It revealed that the samples with post-annealing process had higher values of short circuit current density than the other samples upon pre-annealing. And the interesting high short circuit current density features were observed at 1:1 mixing ratio and 1wt% of P3HT:PCBM.

• The Journal of the Convergence on Culture Technology
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• v.7 no.4
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• pp.659-665
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• 2021

Short video applications (e.g., TikTok, YouTube shorts) are growing quickly in terms of active users and usage time. Of course, advertising industry is utilizing the app as AD channel. The current study, however, argues that the effectiveness of ADs in short video apps are not articulated well and that precise research for measuring the effect is required. In this context, this study measured the effects of storytelling ad types(reality, parody, creative) and message sensation value(high vs. low level) on story transportation. The notable finding is that when creative storytelling ad type which requires more cognitive resources than other two types meets high level of message sensation value, ad viewers could reach cognitive overload state which induced low effectiveness of ad. As its result, the effectiveness of AD reduced. More specific theoretical discussion and suggestions for advertising producers are described.