• Structural Engineering and Mechanics
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• v.68 no.1
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• pp.95-101
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• 2018

The low rate of penetration and short lifetime of drilling bit served as the most common problems encountered in hard formation drilling, thus leading to severe restriction of drilling efficiency in oil and gas reservoir. This study developed a new local impact drilling method to enhance hard formation drilling efficiency. The limitation length formulas of radial/lateral cracks under static indentation and dynamic impact are derived based on the experimental research of Marshall D.B considering the mud column pressure and confining pressure. The local impact rock breaking simulation model is conducted to investigate its ROP raising effect. The results demonstrate that the length of radial/lateral cracks will increase as the decrease of mud pressure and confining pressure, and the local impact can result in a damage zone round the impact crater which helps the rock cutting, thus leading to the ROP increase. The numerical results also demonstrate the advantages of local impact method for raising ROP and the vibration reduction of bit in hard formation drilling. This study has shown that the local impact method can help raising the ROP and vibration reduction of bit, and it may be applied in drilling engineering.

• Smart Structures and Systems
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• v.24 no.6
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• pp.783-791
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• 2019

Prefabricated reinforced-concrete shear walls are used extensively in building structures because they are convenient to construct and environmentally sustainable. To make large walls easier to transport, they are divided into smaller segments and then assembled at the construction site using a variety of connection methods. The present paper proposes a precast shear wall assembled using steel shear keys, wherein the shear keys are fixed on the embedded steel plates of adjacent wall segments by combined plug and fillet welding. The anchoring strength of shear keys is known to affect the mechanical properties of the wall segments. Loading tests were therefore performed to observe the behavior of precast shear wall specimens with different anchoring components for shear keys. The specimen with insufficient strength of anchoring components was found to have reduced stiffness and lateral resistance. Conversely, an extremely high anchoring strength led to a short-column effect at the base of the wall segments and low deformation ability. Finally, for practical engineering purposes, a design approach involving the safety coefficient of anchoring components for steel shear keys is suggested.

• Journal of the Earthquake Engineering Society of Korea
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• v.23 no.4
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• pp.201-209
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• 2019

Response modification factors of school facilities for non-seismic RC moment frames with partial masonry infills in 'Manual for Seismic Performance Evaluation and Retrofit of School Facilities' published in 2018 were investigated in the preceding study. However, since previous studies are based on 2D frame analysis and limited analysis conditions, additional verification needs to be performed to further apply various conditions including orthogonal effect of seismic load. Therefore, this study is to select appropriate response modification factors of school facilities for non-seismic RC moment frames with partial masonry infills by 3D frame analysis. The results are as follows. An appropriate response modification factor for non-seismic RC moment frames with partial masonry infills is proposed as 2.5 for all cases if the period is longer than 0.6 seconds. Also if the period is less than 0.4 seconds and the ratio of shear-controlled columns is less than 30%, 2.5 is chosen too. However, if the period is less than 0.4 seconds and the ratio of shear-controlled columns is higher than 30%, the response modification factor shall be reduced to 2.0. If the period is between 0.4 and 0.6 seconds, then linearly interpolates the response correction factor.

• Structural Monitoring and Maintenance
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• v.11 no.1
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• pp.1-18
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• 2024

Self-compacting concrete is widely used around the globe today due to its special and unique properties. This study examines the effect of natural and crushed gravel combinations in different percentages in short-and long-term properties of concrete. The best utilized sand had a fineness modulus of 2.7. In the mentioned mix designs, silica fume was used with 0 and 7% of the weight of the cement. In order to check the properties of fresh and hardened concrete, 9 and 5 test types were performed, respectively. The carried out tests were slump flow, V-funnel, J-ring, L-box, U-box and column segregation for fresh concrete, and compressive, tensile and flexural strengths for hardened concrete. A mix with only 100% natural gravel was considered as the control mix. According to the results, the control mix design and the one containing 100% crushed gravel with silica fume were the best in fresh and hardened concrete tests, respectively. Finally, using the optimization method, a mix design with 25% natural gravel, 75% crushed gravel and silica fume was introduced as the best mix in terms of the results of both fresh and hardened concrete tests.

• Computers and Concrete
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• v.25 no.2
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• pp.95-109
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• 2020

This paper aims to analytically study the effect of loading conditions and confinement type on the mechanical properties of the concrete-steel composite columns under axial compressive loading. The axial loading is applied to the composite columns in the two ways; only on the concrete core, and on the concrete core and steel tube simultaneously, which are called steel tube-confined concrete (STCC) and concrete-filled steel tube (CFST) columns, respectively. In addition, the confinement is investigated in the three types of passive, short-term active and long-term active confinement. Nonlinear finite element 3D models for analyzing these columns are developed using the ABAQUS program, and then these models are verified with respect to the recent experimental results reported by the authors on the STCC and CFST columns experiencing active and passive confinements. Axial and lateral stress-strain curves as well as the failure mode for qualitative verification, and compressive strength for quantitative verification are considered. It is found that there is a good consistency between the finite element analysis results and the experimental ones. In addition, a parametric study is performed to evaluate the effect of axial loading type, prestressing ratio, concrete compressive strength and steel tube diameter-to-wall thickness ratio on the compressive behavior of the composite columns. Finally, the compressive strength results of CFST specimens obtained via the finite element analysis are compared with the values specified by the international codes and standards including EC4, CSA, ACI-318, and AISC, with the results showing that ACI-318 and AISC underestimate the compressive strength of the composite columns, while EC4 and CSA codes present overestimated values.

• Journal of Applied Biological Chemistry
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• v.61 no.4
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• pp.397-403
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• 2018

The leaves of Spiraea prunifolia were extracted with 80% aqueous MeOH and the concentrates were partitioned into EtOAc, n-BuOH, and $H_2O$ fractions. The repeated $SiO_2$ or ODS column, and medium pressure liquid chromatographies for the n-BuOH fraction led to isolation of two phenolic glucosides. The chemical structures of these compounds were determined as isosalicin (1) and crenatin (2) based on spectroscopic analyses including Nuclear magnetic resonance and MS. Extracts were analyzed using UPLC-MS/MS providing a short analysis time within 5 min using MRM technique. The concentration of crenatin was higher as 9.53 mg/g and isosalicin was lower as 0.65 mg/g. Neuroprotective effects of these compounds against hydrogen peroxide ($H_2O_2$)-induced neurotoxicity were evaluated. The results showed that exposure to $H_2O_2$ induced morphological changes, cell death and neurotoxicity in SK-N-MC cells. However, pretreatment with crenatin resulted in inhibition of morphological change, reduction of loss of cell viability and attenuation of neuronal damage. These results suggested that neuroprotective effect of crenatin isolated from S. prunifolia can be a good candidate for the development of health beneficial foods which can ameliorate the degenerative neuronal disease caused by oxidative stress.

• Journal of the Korean Geotechnical Society
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• v.31 no.9
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• pp.5-15
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• 2015

In this study, rainfall-induced slope stability and coupling effect are investigated using hydro-mechanical finite element model. This model is developed by formulating constitutive and coupled balance equations and is verified by comparing the numerical results with field matric suction. The homogeneous soil layer (soil column) and soil slope are modeled by this model, and the results of variation in matric suction, mean effective stress, porosity, displacement, factor of safety are compared with those of staggered analysis. It is found that the vertical and horizontal displacement from coupling analysis considering change in porosity is larger than that of staggered analysis. The displacement and matric suction from coupling analysis by rainfall infiltration can affect slope instability, which shows a progressive failure behavior. The lowest factor of safety is observed under short-term rainfall. This results confirm the fact that coupling analysis is needed to design soil slope under severe rain condition.

• Steel and Composite Structures
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• v.36 no.4
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• pp.383-398
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• 2020

This paper investigates the progressive collapse behavior of 3D steel-framed gravity buildings under fires with a cooling phase. The effect of fire protections and bracing systems on whether, how, and when a gravity building collapses is studied. It is found that whether a building collapses or not depends on the duration of the heating phase, and it may withstand a "short-hot" fire, but collapses under a mild fire or a "long-cool" fire. The collapse time can be conservatively determined by the time when the temperature of steel columns reaches a critical temperature of 550 ℃. It is also found that the application of a higher level of fire protection may prevent the collapse of a building, but may also lead to its collapse in the cooling phase due to the delayed temperature increment in the heated members. The tensile membrane action in a heated slab can be resisted by a tensile ring around its perimeter or by tensile yielding lines extended to the edge of the frame. It is recommended for practical design that hat bracing systems should be arranged on the whole top floor, and a combination of perimeter and internal vertical bracing systems be used to mitigate the fire-induced collapse of gravity buildings. It is also suggested that beam-to-column connections should be designed to resist high tensile forces (up to yielding force) during the cooling phase of a fire.

• Korean Journal of Pharmacognosy
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• v.30 no.4
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• pp.355-362
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• 1999

New lectins have been isolated and purified from mung bean (Phaseolus radiatus) through physiological saline extraction, ammonium sulfate salt fractionation and column chromatographies. Ion exchanger were eluted by linear salt gradient and then further purified through gel filtration. Thus obtained lectin named as MBL. The gene expressions of 5 cytokines (IL-1, IL-2, IL-6, $TNF-{\aphpa}$ and $IFN-{\gamma}$) from human peripheral blood mononuclear cells (PBMC) stimulated with MBL were investigated by using reverse transcription polymerase chain reaction (RT-PCR). PBMC ($1{\times}106$ cells/ml) isolated from healthy volunteers were stimulated with lectins (4 mg/ml) for various time intervals (1 to 96 hrs). After each of the various stimulated times, total RNA was isolated and assessed for different cytokines mRNA by RT-PCR. The mRNA encoding IL-1, IL-2 were detected continuously from 1 to 20 hrs, and IL-6 was detected up to 24 hrs. But the mRNA encoding $IFN-{\gamma}$ and $TNF-{\alpha}$ were detected to 8 hours only and showed short time response compared with other cytokines. The significant expression of all cytokines mRNA were observed at 4 hrs. These results suggested that MBL, as inducer of cytokines could elicit detectable cytokine mRNA from PBMC.

• Steel and Composite Structures
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• v.44 no.3
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• pp.295-307
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• 2022

The objective of this research is to study experimentally the behavior of stiffened steel tubes (CFSTs). Considered parameters are stiffening methods by through-bolts or shear connectors with different configurations. In addition, the effect of global (ratio between length to diameter) and local (proportion between diameter to thickness) slenderness ratios are investigated. Load application either applied on steel only or both steel and concrete is studied as well. Case of loading on steel only happens when concrete inside the column shrinks. The purpose of the research is to improve the behavior of CFSTs by load transfer between them and different stiffening methods. A parametric experimental study that incorporates thirty-three specimens is carried out to highlight the impact of those parameters. Different outputs are recorded for every specimen such as load capacities, vertical deflections, longitudinal strains, and hoop strains. Two modes of failure occur, yielding and global buckling. Shear connectors and through-bolts improve the ultimate load by up to 5% for sections loaded at steel with different studied global slenderness and local slenderness equal 63.5. Meanwhile, shear connectors or through bolts increase the ultimate load by up to 6% for global slenderness up to 15.75 for sections loaded on composite with local slenderness equals 63.50. Recommendations for future design code development are outlined.