• Title/Summary/Keyword: Shock index

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Identification of heat shock protein70-2 and protamine-1 mRNA, proteins, and analyses of their association with fertility using frozen-thawed sperm in Madura bulls

  • Zulfi Nur Amrina Rosyada;Berlin Pandapotan Pardede;Ekayanti Mulyawati Kaiin;Ligaya I.T.A Tumbelaka;Dedy Duryadi Solihin;Bambang Purwantara;Mokhamad Fakhrul Ulum
    • Animal Bioscience
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    • v.36 no.12
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    • pp.1796-1805
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    • 2023
  • Objective: This study aims to identify heat shock protein70-2 (HSP70-2) and protamine-1 (PRM1) mRNA and protein in Madura bull sperm and demonstrate their relation as bull fertility biomarkers. Methods: The Madura bull fertility rates were grouped based on the percentage of first service conception rate (%FSCR) as high fertility (HF) (79.04%; n = 4), and low fertility (LF) (65.84%; n = 4). mRNA of HSP70-2 and PRM1 with peptidylprolyl isomerase A (PPIA) as a housekeeping gene were determined by quantitative real-time polymerase chain reaction, while enzyme-linked immunoassay was used to measure protein abundance. In the post-thawed semen samples, sperm motility, viability, acrosome integrity, and sperm DNA fragmentation index were analyzed. Data analysis was performed on the measured parameters of semen quality, relative mRNA expression, and protein abundance of HSP70-2 and PRM1, among the bulls with various fertility levels (HF and LF) in a one-way analysis of variance analysis. The Pearson correlation was used to analyze the relationship between semen quality, mRNA, proteins, and fertility rate. Results: Relative mRNA expression and protein abundance of HSP70-2 and PRM1 were detected and were found to be highly expressed in bulls with HF (p<0.05) and were associated with several parameters of semen quality. Conclusion: HSP70-2 and PRM1 mRNA and protein molecules have great potential to serve as molecular markers for determining bull fertility.

Critical Low Temperature and Response of Behavioral Tolerance in Red Seabream Pagrus major fingerlings Exposed to Cold Shock (저온 충격에 노출된 참돔 Pagrus major 치어의 임계 저 수온 및 행동 내성 반응)

  • Yoon, Sung Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.1
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    • pp.575-584
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    • 2021
  • The critical low temperature and response of the behavioral tolerance of red sea bream Pagrus major fingerlings were determined using the continuous behavior monitoring system (CBMS). The behavior of the experimental organisms was observed by decreasing the water temperature by 2.0℃ and 4.0℃ every 12 hours and 24 hours in the range of 8.0-20.0℃. An unstable behavior pattern was observed in red seabream fingerlings exposed to water temperatures below 12.0℃, in which the swimming activity decreased and repeatedly stopped, regardless of the exposure time and water temperature fluctuation. The swimming ability of the organisms exposed to 8.0-10.0℃ decreased sharply, and the behavior of staying at the bottom of the test tank was observed. Only 50 % of the organisms survived due to the low-temperature stress, and all individuals died within six hours after the cold shock. In addition, the behavior index (BI) decreased rapidly, and the amplitude change of the coefficient of variation (CV) was found to have a greater variation than the other water temperatures (p<0.05). Low-temperature stress of red sea bream is promoted at 12.0℃, and it is interpreted as the tolerance limit, which can induce a sublethal response of the organisms exposed to cold shock of 8.0-10.0℃.

The Relationship between Apartment Price Index and Naver Trend Index (아파트가격지수와 네이버 트렌드지수 간의 연관성)

  • Yoo, Han-Soo
    • Land and Housing Review
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    • v.13 no.4
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    • pp.45-53
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    • 2022
  • This paper investigates empirically the lead-lag relation between the 'apartment price index' and 'Internet search volume'. This study uses Naver Trend Index as a proxy for Internet search volume. An increase in Internet search volume on the apartment price index indicates an increase in people's attention to an apartment. Different from previous studies exploring the relation between 'the released price index of the apartment' and 'Naver Trend Index', this study investigates the relation of the Naver Trend Index with 'the fundamental price component of an apartment' and 'the transitory price component of an apartment', respectively. The results of the Granger causality test reveal that there are bidirectional Granger causalities between the 'released price' and Naver Trend Index. In addition, the 'fundamental price component of an apartment' and Naver Trend Index have a feedback relation, while 'the transitory price component of an apartment' Granger causes the Naver Trend Index uni-directionally. The impulse response function analysis indicates that the shock of apartment prices increases Naver Trend Index in the first month. Overall, The close relationship between apartment prices and Naver Trend Index suggests that increases in the movement of apartment prices are positively associated with public attention on the apartment market.

A Study on the Impact of Oil Price Volatility on Korean Macro Economic Activities : An EGARCH and VECM Approach (국제유가의 변동성이 한국 거시경제에 미치는 영향 분석 : EGARCH 및 VECM 모형의 응용)

  • Kim, Sang-Su
    • Journal of Distribution Science
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    • v.11 no.10
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    • pp.73-79
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    • 2013
  • Purpose - This study examines the impact of oil price volatility on economic activities in Korea. The new millennium has seen a deregulation in the crude oil market, which invited immense capital inflow into Korea. It has also raised oil price levels and volatility. Drawing on the recent theoretical literature that emphasizes the role of volatility, this paper attends to the asymmetric changes in economic growth in response to the oil price movement. This study further examines several key macroeconomic variables, such as interest rate, production, and inflation. We come to the conclusion that oil price volatility can, in some part, explain the structural changes. Research design, data, and methodology - We use two methodological frameworks in this study. First, in regards to the oil price uncertainty, we use an Exponential-GARCH (Exponential Generalized Autoregressive Conditional Heteroskedasticity: EGARCH) model estimate to elucidate the asymmetric effect of oil price shock on the conditional oil price volatility. Second, along with the estimation of the conditional volatility by the EGARCH model, we use the estimates in a VECM (Vector Error Correction Model). The study thus examines the dynamic impacts of oil price volatility on industrial production, price levels, and monetary policy responses. We also approximate the monetary policy function by the yield of monetary stabilization bond. The data collected for the study ranges from 1990: M1 to 2013: M7. In the VECM analysis section, the time span is split into two sub-periods; one from 1990 to 1999, and another from 2000 to 2013, due to the U.S. CFTC (Commodity Futures Trading Commission) deregulation on the crude oil futures that became effective in 2000. This paper intends to probe the relationship between oil price uncertainty and macroeconomic variables since the structural change in the oil market became effective. Results and Conclusions - The dynamic impulse response functions obtained from the VECM show a prolonged dampening effect of oil price volatility shock on the industrial production across all sub-periods. We also find that inflation measured by CPI rises by one standard deviation shock in response to oil price uncertainty, and lasts for the ensuing period. In addition, the impulse response functions allude that South Korea practices an expansionary monetary policy in response to oil price shocks, which stems from oil price uncertainty. Moreover, a comparison of the results of the dynamic impulse response functions from the two sub-periods suggests that the dynamic relationships have strengthened since 2000. Specifically, the results are most drastic in terms of industrial production; the impact of oil price volatility shocks has more than doubled from the year 2000 onwards. These results again indicate that the relationships between crude oil price uncertainty and Korean macroeconomic activities have been strengthened since the year2000, which resulted in a structural change in the crude oil market due to the deregulation of the crude oil futures.

Implementation of a Prefetch method for Secondary Index Scan in MySQL InnoDB Engine (MySQL InnoDB엔진의 Secondary Index Scan을 위한 Prefetch 기능 구현)

  • Hwang, Dasom;Lee, Sang-Won
    • Journal of KIISE
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    • v.44 no.2
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    • pp.208-212
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    • 2017
  • Flash SSDs have many advantages over the existing hard disks such as energy efficiency, shock resistance, and high I/O throughput. For these reasons, in combination with the emergence of innovative technologies such as 3D-NAND and V-NAND for cheaper cost-per-byte, flash SSDs have been rapidly replacing hard disks in many areas. However, the existing database engines, which have been developed mainly assuming hard disks as the storage, could not fully exploit the characteristics of flash SSDs (e.g. internal parallelism). In this paper, in order to utilize the internal parallelism intrinsic to modern flash SSDs for faster query processing, we implemented a prefetching method using asynchronous input/output as a new functionality for secondary index scans in MySQL InnoDB engine. Compared to the original InnoDB engine, the proposed prefetching-based scan scheme shows three-fold higher performance in the case of 16KB-page sizes, and about 4.2-fold higher performance in the case of 4KB-page sizes.

Analysis of Risk Factors for Postoperative Morbidity in Perforated Peptic Ulcer

  • Kim, Jae-Myung;Jeong, Sang-Ho;Lee, Young-Joon;Park, Soon-Tae;Choi, Sang-Kyung;Hong, Soon-Chan;Jung, Eun-Jung;Ju, Young-Tae;Jeong, Chi-Young;Ha, Woo-Song
    • Journal of Gastric Cancer
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    • v.12 no.1
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    • pp.26-35
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    • 2012
  • Purpose: Emergency operations for perforated peptic ulcer are associated with a high incidence of postoperative complications. While several studies have investigated the impact of perioperative risk factors and underlying diseases on the postoperative morbidity after abdominal surgery, only a few have analyzed their role in perforated peptic ulcer disease. The purpose of this study was to determine any possible associations between postoperative morbidity and comorbid disease or perioperative risk factors in perforated peptic ulcer. Materials and Methods: In total, 142 consecutive patients, who underwent surgery for perforated peptic ulcer, at a single institution, between January 2005 and October 2010 were included in this study. The clinical data concerning the patient characteristics, operative methods, and complications were collected retrospectively. Results: The postoperative morbidity rate associated with perforated peptic ulcer operations was 36.6% (52/142). Univariate analysis revealed that a long operating time, the open surgical method, age (${\geq}60$), sex (female), high American Society of Anesthesiologists (ASA) score and presence of preoperative shock were significant perioperative risk factors for postoperative morbidity. Significant comorbid risk factors included hypertension, diabetes mellitus and pulmonary disease. Multivariate analysis revealed a long operating time, the open surgical method, high ASA score and the presence of preoperative shock were all independent risk factors for the postoperative morbidity in perforated peptic ulcer. Conclusions: A high ASA score, preoperative shock, open surgery and long operating time of more than 150 minutes are high risk factors for morbidity. However, there is no association between postoperative morbidity and comorbid disease in patients with a perforated peptic ulcer.

The Detection of the Internal Defect in the Glass Using Auto Focusing Method (자동 초점 기법을 이용한 유리 내부 결함 검출)

  • Jy, Yong-Woo;Jhang, Kyung-Young;Jung, Ji-Hwa;Kim, Suk-Jun
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.28 no.7
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    • pp.1047-1054
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    • 2004
  • Internal defects in the glass, like-as micro-voids, micro-cracks, or inclusions, easily cause the failure when the glass is exposed to the shock or the thermal variation. In order to produce the highly reliable glass product, the precision inspection of the defect in the glass is required. For this purpose, this paper proposes a machine vision technique based on the auto-focusing method, which searches the defect and measures the location under the fact that the edge image of defect must be the most clear when the focal plane of CCD camera is coincided with the defect. As for the search index, the gradient indicator is presented. The basic principles are verified through the simulations for the computer-generated defect images, where the affects of defect shape, gray level of background, and the brightness of the defect image are also analyzed. Finally, experimental results for actual glass specimens are shown to confirm the applicability of this method to the actual field.

Asian Stock Markets Analysis: The New Evidence from Time-Varying Coefficient Autoregressive Model

  • HONGSAKULVASU, Napon;LIAMMUKDA, Asama
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.9
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    • pp.95-104
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    • 2020
  • In financial economics studies, the autoregressive model has been a workhorse for a long time. However, the model has a fixed value on every parameter and requires the stationarity assumptions. Time-varying coefficient autoregressive model that we use in this paper offers some desirable benefits over the traditional model such as the parameters are allowed to be varied over-time and can be applies to non-stationary financial data. This paper provides the Monte Carlo simulation studies which show that the model can capture the dynamic movement of parameters very well, even though, there are some sudden changes or jumps. For the daily data from January 1, 2015 to February 12, 2020, our paper provides the empirical studies that Thailand, Taiwan and Tokyo Stock market Index can be explained very well by the time-varying coefficient autoregressive model with lag order one while South Korea's stock index can be explained by the model with lag order three. We show that the model can unveil the non-linear shape of the estimated mean. We employ GJR-GARCH in the condition variance equation and found the evidences that the negative shocks have more impact on market's volatility than the positive shock in the case of South Korea and Tokyo.

A Proposal of New Breaker Index Formula Using Supervised Machine Learning (지도학습을 이용한 새로운 선형 쇄파지표식 개발)

  • Choi, Byung-Jong;Park, Chang-Wook;Cho, Yong-Hwan;Kim, Do-Sam;Lee, Kwang-Ho
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.32 no.6
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    • pp.384-395
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    • 2020
  • Breaking waves generated by wave shoaling in coastal areas have a close relationship with various physical phenomena in coastal regions, such as sediment transport, longshore currents, and shock wave pressure. Therefore, it is crucial to accurately predict breaker index such as breaking wave height and breaking depth, when designing coastal structures. Numerous scientific efforts have been made in the past by many researchers to identify and predict the breaking phenomenon. Representative studies on wave breaking provide many empirical formulas for the prediction of breaking index, mainly through hydraulic model experiments. However, the existing empirical formulas for breaking index determine the coefficients of the assumed equation through statistical analysis of data under the assumption of a specific equation. In this paper, we applied a representative linear-based supervised machine learning algorithms that show high predictive performance in various research fields related to regression or classification problems. Based on the used machine learning methods, a model for prediction of the breaking index is developed from previously published experimental data on the breaking wave, and a new linear equation for prediction of breaker index is presented from the trained model. The newly proposed breaker index formula showed similar predictive performance compared to the existing empirical formula, although it was a simple linear equation.

THE SMOOTHED PARTICLE HYDRODYNAMICS AND THE BINARY TREE COMBINED INTO BTSPH: PERFORMANCE TESTS

  • KIM W. -T.;HONG S. S.;YUN H. S.
    • Journal of The Korean Astronomical Society
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    • v.27 no.1
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    • pp.13-29
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    • 1994
  • We have constructed a 3-dim hydrodynamics code called BTSPH. The fluid dynamics part of the code is based on the smoothed particle hydrodynamics (SPH), and for its Poisson solver the binary tree (BT) scheme is employed. We let the smoothing length in the SPH algorithm vary with space and time, so that resolution of the calculation is considerably enhanced over the version of SPH with fixed smoothing length. The binary tree scheme calculates the gravitational force at a point by collecting the monopole forces from neighboring particles and the multipole forces from aggregates of distant particles. The BTSPH is free from geometric constraints, does not rely on grids, and needs arrays of moderate size. With the code we have run the following set of test calculations: one-dim shock tube, adiabatic collapse of an isothermal cloud, small oscillation of an equilibrium polytrope of index 3/2, and tidal encounter of the polytrope and a point mass perturber. Results of the tests confirmed the code performance.

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