• Restorative Dentistry and Endodontics
• /
• v.43 no.1
• /
• pp.6.1-6.2
• /
• 2018

• Korean Architects
• /
• s.515
• /
• pp.36-41
• /
• 2012

• Restorative Dentistry and Endodontics
• /
• v.44 no.1
• /
• pp.12.1-12.1
• /
• 2019

• KSBB Journal
• /
• v.30 no.1
• /
• pp.44-51
• /
• 2015

Chinese hamster ovary (CHO) cells are the most widely used mammalian host for the commercial production of recombinant proteins. However, they show relatively low yields of recombinant proteins in comparison with microbial cells. Various strategies have been tried to overcome this drawback. The acetyl moieties are attached to the N-terminus of histone by histone acetyltransferase (HAT) while histone deacetylase (HDAC) removes histone-bound acetyl groups. HDAC inhibitor (HDACi), such as sodium butyrate, sodium propionate and valproic acid, can enhance specific productivity of CHO cells. Human albumin-erythropoietin (Alb-EPO) is a novel 105 kDa protein comprising recombinant human EPO fused to human albumin. In this study, we examined the effects of HDACi on the production of Alb-EPO in CHO cells with various concentrations in the range of 0-1 mM. The results showed that sodium butyrate was found to be the best HDACi for enhancing productivity. It enhanced not only the production of Alb-EPO but also the apoptosis of recombinant CHO cells.

• Journal of Korean Medical classics
• /
• v.9
• /
• pp.381-429
• /
• 1996

Choo-Joo(鄒澍;1790-1844) was the medicine scholar who lived in the late peroid of the Chung-Dynasty and wrote "Bon-Kyung-So-Jeung(本經疏證)", "Bon-kyung-Sok-So(本經續疏)", "Bon-Kyng-Seo-So-Yo(本經序疏要)". In the books mentioned above, He annotated the chief effectiveness of herbal medicine(本草) which had been presented on "Shin-Nong-Bon-Cho-Kyung(神農本草經)" and "Myoung-Eui-Byul-Lok(名醫別錄)". He defined medical action of 315 herb-items with the many theories of various scholars. Scholars whom Choo-Joo has qoutated belong to the school of study of Chinese classics, and they have regarded "Hwang-Je-Nae-Kyung(黃帝內經)", "Shin-Nong-Bon-Cho-Kyung(神農本草經)" and "Sang-Han-Lon(傷寒論)" as great important cannon and have lived during the Myoung Chung Dynasty. The distinctive character of Choo-Joo belongs to similar academic traditions. It seems that he was appected mainly by "Bon-Cho-Gang-Mok(本草綱目)" written by Lee-Si-Jin(李時珍), Mok-Jung-Soon(繆仲淳)'s "Sin-Nonng-Bon-Cho-Kyung-So(神農本草經疏)", You-Yak-Guem(劉若金)'s "Bon-Cho-Sul(本草述)" and Yang-Si-Tae(楊時泰)'s "Bon-Cho-Sul-Gu-Won(本草述鉤元)". He contributed in two big sides. First, Choo-Joo(鄒澍) have achieved much contribution in biliographical study of Chinese classics(考證學). He analyzed the medical theory of herb-medicine, combining with "Nae-Kyung(內經)", "Sang-Han-Lon(傷寒論)" and many theory of various scholars in order to make research on the chief effectiveness that had been presented in "Shin-Nong-Bon-Cho-Kyung(神農本草經)". Therefore the practical application of medical theory and term which had been represented on classics were offered. Secondary, Choo-joo did great accomplishment in pharmacology. The point of his theory was grasping the effect of a medicine through distinctive one beyond general feature. He set up standards that grasp distintive feature as form, color, energy and taste, place of production and temper. And on the basis of these standards he investigated distinctive feature on various fields, then he induced 'the Uem-Yang-0-Haeng Theory(陰陽五行說)' from distictions. According to the these method of classification, form(形) stand for the resultant shape of herbal function, color(色) represent the active direction of herb, energy and taste(氣味) imply the ultimate active function of herb, the place of production(産地) and the period of occurrence(發生時期) symbolize symptoms. When he applied these method to seek for effetiveness, he regarded the field which revealed most representative feature as of great importance, and Combining remained distinctions with one another, he determined more accurate medicinal value. These method of obsevation solved contradiction which occured by equaly appling all medical herbs for the regular standard. The most important theory that represented in Choo-Joo(鄒澍) is to induce and to certify the distintive feature of herb into the 'Uem-Yang-0-Haeng Theory'. That is, concluded as "spring(生), growing(長), change(化), collecting(收) and storing(藏)". As the results of these studies, he made clear the action of medicine more concretly and made 'the Uem-Yang-0-Haeng Theory(陰陽五行說)' more concret and actual for applying. And he contrbuted to establish the standard for grasping the effect of medicines.

• Proceedings of the KIEE Conference
• /
• 1999.07d
• /
• pp.1741-1743
• /
• 1999

8A5H monolayers on a water surface were investigated by means of Maxwell displacement current measurement. The displacement current was generated during 8A5H monolayers compressed or irradiation with light. And displacement current pulses were found when photoisomerizations were induced in 8A5H LB films by irradiation with ultraviolet light and visible light.

• Journal of Acupuncture Research
• /
• v.21 no.4
• /
• pp.149-157
• /
• 2004

Objective : The purpose of this study is to research whether Inyeong Chon spot pulse(人迎氣口脈) could be used on application of Ohaeng-acupuncture(五行鍼法). Methods : I research ${\ll}$Naegyeong${\gg}$(內經) and annotations were excerpted and record that notied the Inyeong Chon spot pulse(人迎氣口脈). Results : Comparison of Inyeong Chon spot pulse and Deficiency Excess syndrome of meridian system is useful to use Zheng Ge(正格) and Sheng Ge(勝格) of Ohaeng-acupuncture(五行鍼法) but in application of Han Ge(寒格) and Re Ge(熱格), Inyeong Chon spot pulse(人迎氣口脈) is not useful.

• Herbal Formula Science
• /
• v.12 no.1
• /
• pp.263-276
• /
• 2004

Clinical study on one case of climacteric syndrome induced hysterectomy climacteric syndrome is symptoms of physical, mental, physiological in menopausal period. Importance of treatment of climacteric symptoms was on the rise recently. I have treated one patient who has mental depression, anxiety, impatience, impotence, palpitations, facial flushing, abdominal pain in the menopausal period in Dongshin University Oriental Hospital. I took acupunture, moxibustion, cupping, and also I made herbal medicine-gamiguibitang(加味歸脾湯). As a result, I got a good effect through above methods. So I came to write this case report.

• Journal of Acupuncture Research
• /
• v.21 no.2
• /
• pp.275-286
• /
• 2004

Objective : This study is designed to find out the effects of Cervus elaphus Herbal acupuncture on osteoarthritis in knee joint. Methods : We investigated 15 cases of patients with osteoarthritis in knee joint that arevisited in hospital of Dong-Shin Korean Traditional Medicine. We evaluated knee joint function that before and after its treatment by Lyshoim score and satisfaction of treatment by Baumgaertner nine point sacle and VAS score. Results : The sex distinction with a disease caused much more female than male at the ratio of 1 to 2.75 in the proportion of male to female. Jobs is mainly ranked with a sitting position jobs and a housewife. Approximately 73.3% of cases before our hospital have ever treated at the other clinics or hospitals. According to Lyshoim score, before treatment is 54.87 and after is 63.29, that showd stisfacally meaningful increase. According to VAS score, before treatment is 10 and after is 44.6. In evaluating of satisfaction, good are 73.2% according to Baumgaertner nine point sacle. Conclusion : According to the results, Cervus elaphus Herbal acupuncture may be effects on the increase of knee joints function and the decrease of pain on osteoarthritis in knee joint.

• Journal of Sasang Constitutional Medicine
• /
• v.20 no.3
• /
• pp.208-217
• /
• 2008

1. Background Tremor is a rhythmic, involuntary muscular contraction characterized by oscillations (to-and-fro movements) of a part of the body. Tremor is the common symptom clinically 2. Objectives The purpose of this study is to show a case of tremor patient with tremor improved by Oriental medical treatment which is based on the constitutional medicine. 3. Patient & Methods Patients were diagnosed as Taeumin by physical characteristics, posture, and symptoms and were evaluated with an interview and laboratory tests after Sasang constitutional Medicine 4. Result After Yeoldahanso-tang(熱多寒少湯) medication, Taeumin patients were improved the tremor. 5. Conclusions These case-studies show an efficient result of using Sasang traditional medicine in the treatment of tremor.