• 한국초등과학교육학회지:초등과학교육
• /
• 제17권1호
• /
• pp.33-46
• /
• 1998

This study researched the concepts that elementary school students have after having learned volcano and earthquake. The reacher collected and adjusted the journals related to this study, and sampled the concepts included in Chap. One "Moving Earth", the first term of the elementary school sixth year. The students' descriptive responses were analyzed after subjective questions on the basis of above were developed and put into. After the contents described in the answer sheets were categorized by key words and the types of concept were made out by qualitative analysis, it was showed what was differences between the sexual, regional and achievement levels. The results of this study were as follows; first, though the types of concept about volcano and earthquake were found variably, it was showed that wrong preconception was not corrected, especially the exact understanding about terms not attained to, which led to the trouble in conceptual readjustment of students. Second, though the response rate about the types of scientific concept was found high that volcano was made out of explosion and eruption of magma and lava, there were also children who described not the interior factor of globe but the surface factor. Third, according to the results divided into the interior factor of globe and the surface factor and analyzed about earthquake, there were a great number of children who responded as the surface factor though most of the students responded to the interior factor of globe. Fourth, through some types of concept, it was found that the formation of concept was much influenced by experience of children's life, curriculum, and the method of study. Fifth, In the most test question, the scientific concept was found that boys were higher than girls in the distinction of sex, the children of cities than those of town and island, and the upper group than the lower group in the achievement levels.

• 아태비즈니스연구
• /
• 제13권2호
• /
• pp.155-168
• /
• 2022

Purpose - Although the government and civic groups do not always confront each other over the Me Too movement, the two stakeholders are often conflicted. For example, the two interested parties may have different positions in the gender conflict and be often hostile due to debates over how to institutionalize and distinguish actual harm from innocence. In this situation, the strategies of the two stakeholders for their own ends are inevitably interdependent. This paper is a study on the strategic reciprocity of interested parties in relation to the Me Too Movement, which has recently raised a new discourses in our society. Design/methodology/approach - We derive equilibrium of the reciprocity between civic groups(collectively referred to as the Me Too Movement Headquarters) leading the Me Too Movement and government that must preemptively respond to new social issues, and analyze how changes in some external conditions affect the reactions of the two stakeholders. For this purpose we rely on economic methodology. Findings - In the reciprocity between the two forces, we derive an equilibrium composed of the pair of the government's optimal response level and the civic group's optimal strategy, and further derive the comparative static results according to changes in external conditions. Analysis results are mixed with intuitive results and non-intuitive ones. However, even if the result is not intuitive, rational reasoning is possible as long as it is derived through a rigorous model, and it has several implications. Research implications or Originality - Although this study is a positive approach, it is meaningful as a starting point to explore practical discussion directions and alternatives by adding another new perspective and approach to research in other social science fields with many normative studies.

• Archives of Plastic Surgery
• /
• 제49권6호
• /
• pp.710-715
• /
• 2022

Background The latissimus musculocutaneous flap (LD flap) is a useful option for breast reconstruction following mastectomy. It has the advantage of obtaining sufficient tissue padding and natural shape by using autologous tissue. However, with the emergence of the skin-sparing mastectomy technique and artificial dermis matrix, direct-to-implant (DTI) breast reconstruction has become the first choice of surgery. The purpose of this study was to compare the satisfaction levels of patients who underwent DTI and LD flap with implant using patient-reported Breast-Q results. Methods A retrospective study was performed reviewing the records of 49 women who underwent immediate breast reconstruction with DTI or LD flap with implant and responded to the BREAST-Q questionnaire after the operation. The patient-reported breast-Q results were analyzed and correlated to the demographic information and intraoperative information. Results A total of 26 patients who underwent reconstruction with LD flap with implant and 23 patients with DTI were identified and responded to the questionnaire after an average of 32.3 and 10.4 months postoperation, respectively. According to the patient response to the breast-q values, satisfaction with breast was 60.0 and 57.0 points, psychosocial well-being 61.0 and 60.0 points, and sexual well-being 41.0 and 43.0 points in the two groups. Overall, there was no significant difference in the breastQ score between the two groups. Conclusion Patients who underwent DTI breast reconstruction seemed equally satisfied with the appearance and outcome of their breast reconstruction compared with LD flap with implant. Therefore, it appears that DTI is adequately replacing LD with implant.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제15권2호
• /
• pp.143-151
• /
• 2004

연구목적：소아·청소년기 발병 강박장애는 낮은 약물반응, 높은 공존장애율, 강한 유전적 경향성을 가진다고 알려져 왔다. 그러나 현재까지 국내에서 소아·청소년기 발병 강박장애에 대한 연구는 극히 미미하다. 이에 본 연구에서는 서울대학교병원 소아·청소년 정신과 병동에 입원한 강박장애 아동들을 대상으로 임상양상, 유전부하, 약물 반응양상, 퇴원후의 경과등을 조사하여, 심각한 증상을 보이는 소아·청소년 강박장애 군의 특성을 파악하려 하였다. 방 법：최근 9년사이에 서울대병원 소아·청소년 정신과에 입원한 환아 20명(남 16, 여 4)의 자료를 조사하였고 이를 대상으로 임상적 특성을 조사하였다. 진단 및 임상 상의 정확성을 유지하기 위해 의무기록지, 심리학적 보고서, 가족 면담 자료, 간호 보고서를 모두 고려하였고, 퇴원시 확정된 진단을 일차진단으로 하였다. 결 과：1) 환아의 성비는 남성이 4：1로 우위였다. 2) 강박사고에 있어서 가장 흔한 형태는 병적의심이었고, 이어서 더러움에 대한 공포, 공격적 사고, 대칭에의 요구, 성적 강박 사고였다. 강박행동에서 가장 흔한 내용은 확인, 씻기, 숨쉬기, 움직임, 대칭, 반복적 질문, 물건수집, 정신적 강박행동 등이었다. 3) 가장 흔한 공존 장애는 우울증이었고, 그 다음으로는 다른 불안장애, 틱장애, 품행장애, 반항장애였다. 드물게 강박사고에 대한 현실검증력이 손상된 것으로 판단되는 아동도 발견되었다. 4) 정신과 질환에 대한 가족력을 살펴본 결과, 17 가족(85%)에서 2차 친척 중 정신과 장애를 앓는 사람이 발견되었다. 그리고, 강박 스펙트럼 장애로 의심되는 친척을 둔 아동이 전체의 45%(9명)이었다. 5) 약물치료로서 사분의 삼 정도의 환아들(75%)이, SSRI와 항정신병약물을 함께 복용하고 있었고, 치료 반응상 CGI에서 중등도 호전(moderate improved) 이상을 보이는 경우가 75%로 파악되었다. 6) 퇴원 후의 외래 추적 결과, 지속적인 증상의 관해를 보인 경우는 5명(25%)이었고, 부분적인 증상을 가진 채 만성적으로 지속되는 경우가 10명(50%)이었다. 결 론：심각한 소아·청소년 강박장애약물 환아들의 임상상을 국내에서는 최초로 체계적으로 조사하였다. 그 결과, 높은 공존장애율, 높은 정신과장애의 가족력, 높은 항정신병약물 복용을 보이는 것으로 조사되었다. 증상면에서도 공격적-성적 강박사고의 비율이 높았으며, 숨쉬기, 움직이기 등의 특이한 강박행동이 발견되었다. 치료로서 사분의삼 정도의 환아들(75%)이, SSRI와 항정신병약물을 함께 복용하고 있었고, 치료 반응상 CGI에서 중등도 호전(moderate improved) 이상을 보이는 경우가 75%로 파악되었다.

• 한국균학회지
• /
• 제41권1호
• /
• pp.1-8
• /
• 2013

Cop9 signalosome(CSN)은 최초 식물 발달 과정에서의 빛에 의한 전사 조절 과정에서의 억제 유전자로 처음 분리된 이후 이들이 다양한 진핵 생물 에서 매우 잘 보존되어 있음이 알려지게 되었다. 이들은 대부분 8개의 subunit으로 구성되며 26S proteasome lid와 eIF3와 구조적으로는 물론 기능적으로도 유사성을 보인다고 알려져 있다. 이들은 특히 Cullin-Ring ubiquitin ligases(CRL)의 구성 요소인 Cullin의 deneddylation을 매개하여 ubiquitin ligase의 활성을 조절한다고 알려져 있으며, 또한 세포 주기 및 checkpoint 조절에 관여한다고 보고되었다. 분열효모의 경우 CSN1 및 CSN2 결손 세포에서 S-phase로서의 진행이 지연됨이 관찰되었고 감마선 혹은 UV에 좀더 민감해지는 현상이 관찰되어 CSN이 checkpoint 조절에 관여한다는 것을 보여주었다. 곰팡이의 CSN 경우 구조적으로 더욱 상위 개체들의 그것과 더욱 유사한데, CSN이 생체 시계 리듬, 빛과 연관한 호르몬 생산, 곰팡이의 발달 과정 및 생식 주기를 조절함이 보고되었다. 또한 Aspergillus nidulans의 경우 상위개체에서 보여준 DNA 합성 및 손상, 세포 주기 조절에서의 기능이 알려지면서 CSN은 곰팡이 생활사에 필수적인 여러 과정들을 조절하는 중요한 인자임을 알 수 있다. 이로써 식물이나 포유동물 등에서 보고되었던 CSN의 주요 기능을 미생물에서도 대부분 공유하고 있음을 알 수 있고 이들이 CRL을 통한 주요 세포 활성 조절 연구에 좋은 툴로서 활용할 수 있음을 시사하고 있다.

• 한국가금학회지
• /
• 제19권4호
• /
• pp.187-195
• /
• 1992

본 연구는 난용종 순종계의 특정 집단의 주요 경제형질에 대한 단기 산란검정기록을 이용하여 유전적 개량량을 추정하기 위해 수행하였다. 통계분석에 이용된 자료는 단관 백색 레그혼종 F, K 계통에 대한 1986년부터 1991년까지 6세대간 선발결과의 기록으로서 주요 선발형질은 270일령 산란수, 시산일령, 270일령 난중 및 체중으로 분석한 결과는 다음과 같다. 1. 각 계통별 평균능력을 보면 시산일령은 매 세대당 1.94일(K) 1.32일(F)씩 감소되었고 체중은 15.39(K), 16.5g(F)씩 감소되었다. 난중은 0.09(K), -0.05g(F)씩 증가되었고 산란수는 0.56(K), -0.78(F)의 증가를 보였다. 2. 조사형질 모두의 예상 선발차에 대한 실현 선발차의 비율이 세대경과에 따라 유의하게 감소되지 않았다. 3. 분산성분에 의한 유전모수는 시산일령이 평균 0.28(F), 0.40(K), 270일령 체중이 0.29(F), 0.39(K), 산란수 (270일)가 0.25(F), 0.29(K), 270일령 난중이 0.51(F), 0.48(K)으로 추정되었다. 4. 세대당 유전적 개량은 F, K 계통 모두 일정한 경향치를 보이지 않았고 시산일령이 -2.46(F), -1.94(K), 산란수 2.01(F), 2.25(K), 270일령 난중이 0.54(F), 0.64(K)으로 추정되었다.

• 한국산학기술학회논문지
• /
• 제18권10호
• /
• pp.652-662
• /
• 2017

본 연구는 간호대학생이 임상실습 중 경험하는 폭력, 폭력에 대한 반응과 차후 행동을 알아내기 위함이다. 조사연구가 실시되었고, 자료는 2012년 4월 30일부터 7월 6일까지 수집되었다. 4개 도시의 6개 대학에서 290명의 간호대학생을 대상으로 자기설문방식이 사용되었다. 약 91%의 학생들이 폭력을 당하였다. 언어적 폭력(85.2%)이 가장 빈번하게 맞닥뜨리는 폭력의 종류였고, 신체적 위협(74.8%), 성폭력(41.0%), 신체적 폭력(26.2%)의 순서였다. 참가자들은 환자 또는 환자 가족, 의사 및 간호사와 같은 임상스탭에 의해 학대를 당하였다. 간호대학생은 폭력에 노출된 이후 생리적 또는 사회적인 면보다는 심리적인 면에서 더 부정적으로 반응하였다. 대부분의 학생들의 대처 행동은 "폭력을 가한 사람에게 반응하지 않고, 임상실습을 지속함 (51.7%)"이었고, 이러한 반응은 폭력을 경험한 후의 대처행동에서 가장 빈번하게 사용되었다(79.5%). 간호대학생이 임상 현장에서 경험하는 폭력을 예방할 수 있도록 하는 전략이 수립되어야하며, 학생들은 교육 과정에서 폭력에 대처할 수 있는 의사소통 및 방법과 관련된 정보를 제공 받을 수 있어야 한다.

• 대한핵의학회지
• /
• 제6권1호
• /
• pp.25-32
• /
• 1972

The plasma HGH concentrations were assayed in total 138 cases by the radioimmunoassay. The groups of control, typhoid fever, epidemic hemorrhagic fever, tuberculous meningitis and other febrile diseases were studied, also were the groups of hyperthyroidism, acromegaly and hypopitutarism. Insulin stimulation test was performed in control, typhoid fever and hypopituitarism. In the control group, the plasma HGH concentration in fasting (early morning) was $2.06{\pm}1.183m{\mu}g/ml$ and its upper limit was $4.5m{\mu}g/ml$. No sexual difference was observed. By the insulin stimulation, plasma HGH concentration had rised to the peak level of $24.1{\pm}15.71m{\mu}g/ml$, 60 min. after the intravenous insulin injection, then decreased to the normal level progressively. In typhoid fever, fasting HGH concentrations in febrile state and in defeverence were $2.5{\pm}1.35m{\mu}g/ml\;and\;2.2{\pm}3.32m{\mu}g/ml$ respectively, showing no significant difference with the control group. However, the levels of individual cases ranged widely, conpared with the control group. The response to the insulin stimulation test was similar to the control group. In epidemic hemorrhagic fever the HGH concentrations in oliguric phase, in diuretic phase and in convalescence were $4.2{\pm}3.71m{\mu}g/ml,\;2.2{\pm}1.30m{\mu}g/ml\;and\;3.4{\pm}3.01m{\mu}g/ml$ respectively. No significant differences were observe compared to the control, but they showed wide range of plasma HGH levels. In tuberculous meningitis, the fasting HGH concentration was $2.9{\pm}1.42m{\mu}g/ml$. In the other febrile diseases, the value was $2.5{\pm}2.23m{\mu}g/ml$. In 4 cases of hypopituitarism, the fasting HGH concentration was $2.3{\pm}0.42m{\mu}g/ml$ and ranged normally. However, the response to the insulin stimulation test was not observed. Very high plasma HGH concentrations were observed in acromegalic patients.

• 한국안광학회지
• /
• 제11권3호
• /
• pp.187-192
• /
• 2006

본 연구 목적은 조절반응량을 측정할 수 있는 양얀개방형 자동굴절검사기(auto-refractometer)를 이용하여 정시안의 실제 조절반응량을 알아보고자 하였다. 나안시력이 1.0 이상이며 등기구면굴절력이 ${\pm}0.50D$ 이하이고, 난시도수가 -0.75D 이하인, 10세부터 59세사이(평균 $25.8{\pm}12.4$) 377안(남 146안, 여 231안)을 10세 간격의 연령군으로 나누어 조절반응량, 원근거리 난시도수와 난시축 변화를 분석하였다. 연령별 조절반응량은 전체 평균은 1.47D, 10대 1.63D, 20대 1.57D, 30대 1.71D, 40대 0.97D, 50대 0.05D로 10대에서 30대까지는 약간 증가를 보였으나, 40대 이상에서 현저한 저하를 보이다가 50대에는 거의 반응하지 않는 것으로 나타났다. 성별 차이는 남자는 평균 연령 $26.4{\pm}12.3$에 조절반응량은 1.56D, 여자는 $25.5{\pm}12.5$에 1.43D로 남자가 약간 높게 나타났다. 원근거리에서 난시도수의 변화는 전체 평균은 +0.12D, 10대 +0.06D, 20대 +0.16D, 30대 +0.09D, 40대 +0.05D, 50대 +0.06D, 남자 +0.16D, 여자 +0.09D로 모든 군에서 의미 있는 차이는 없었지만, 원거리보다 근거리에서 모두 군에서 난시가 높게 나타났다. 난시축 변화는 원거리 난시축에 비해 ${\pm}10^{\circ}$ 미만으로 변한 경우가 103안(33%), 시계방향으로 $10^{\circ}$ 이상 회전이 108안(34.6%), 반사계방향으로 $10^{\circ}$ 이상 회전이 101안(32.4%)으로 나타나 근거리에서 난시축의 변화가 있는 것으로 분석되었다.

• 한국학교보건학회지
• /
• 제17권1호
• /
• pp.1-12
• /
• 2004

Purpose : this study purposed to investigate school nursing phenomena in Korea by applying ICNP, the international standard nursing classification system developed by ICN, and to compare school nursing phenomena at elementary, middle and high schools. Method : The subjects of this study are 110 nursing teachers from 82 elementary schools, 16 middle schools, and 12 high schools. In the survey, subjects were asked to score the degree to which phenomena and characteristics of Korean school nursing, identified in previous research, on a 5 point scale. Questionnaires were distributed and recovered by mail and email. The period of data collection was 6 months from July to December 2003. The general characteristics of schools and nursing teachers were represented with frequencies and percentages, the phenomena and characteristics of school nursing with the mean score of the questions, and the phenomena school nursing by school grade with ANOVA and Duncan's posterior analysis. Results : 1) As for the characteristics of schools according to school nursing phenomena related to human behavior, the mean score of questions on inadequate stress management was highest at 3.24 points followed by the score on inadequate weight control (3.23), inadequate eating habits (3.22), the risk of spine disorders (2.68), inadequate emergency management (2.62), inadequate response to sex -related problems (2.19), and smoking and drug use (1.85). 2) As for the characteristics of schools according to school nursing phenomena related to human function, the mean score of questions on oral health management was highest at 3.11 points followed by the score on the risk of digestive system disorder (2.87), improper eyesight management (2.81), the risk of respiratory system disorders (2.75), lack of sexual identity (2.52), and inadequate contagious disease control (2.12). 3) As for the mean score according to school nursing phenomena related to environment, the score of the risk of accidents in classroom was highest as 2.68 points followed by the score of the risk of accidents around the school (2.65), maladjustment to school (2.62), the risk of accidents outside the classroom (2.43), inadequate learning environment (1.83), the risk of exposure to socially and physically harmful environment factors (1.82), and inadequate waste disposal (1.77). 4) This study tested the mean scores of questions corresponding to each school nursing phenomenon in order to see if there is a difference in the school nursing phenomenon among elementary, middle and high schools, and performed Duncan's posterior comparison for school nursing phenomena. A significant difference was found at p<.1. According to the results, school nursing phenomena found to be significantly different among elementary, middle and high schools was smoking and drug use (p<.05), which appeared more problematic in high school than in elementary school. phenomena such as inadequate eating habits, inadequate weight control, inadequate response to sex-related problems and inadequate waste disposal were also found to be statistically different at p<.1; however, according to the result of Duncan's posterior comparison, no difference was found among groups in improper eating habits and improper response to sex-related problems, and a significant difference was found between middle and high schools in inadequate weight control and inadequate waste disposal. Conclusion: Based on the results of this study, it is necessary to plan school health projects focused on the characteristic school nursing phenomena that had high scores and to develop and execute school healthe projects in accordance with the characteristics of elementary, middle and high schools. Considering that the scores of school nursing phenomena related to human behavior are high, it is necessary to introduce school health promotion projects in a systematic way.