• 한국컴퓨터정보학회논문지
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• 제16권7호
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• pp.95-103
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• 2011

보다 신속하고 정확한 정보 검색에 대한 지능적이고 자동화 된 서비스 제공을 지향하는 시맨틱웹 기술의 실제적 활용이 점점 구체화 되고 있다. 이에 시맨틱 웹상에서 존재하는 방대한 양의 데이터를 관리하기 위한 표준 포맷 중 하나로 널리 사용되는 RDF로 표현된 데이터에 대한 효율적인 질의 처리는 계속적인 중요한 연구 주제가 되고 있다. RDF 데이터에 대한 전형적인 질의 처리유형은 임의의 리소스로부터 특정한 관계성을 갖는 리소스들을 검색하는 것으로 이에 대한 많은 연구들이 진행되어 왔다. 그러나, 기존의 연구들에서는 리소스간의 복잡한 관계성들의 발견(discovery) 즉, 질의 처리의 결과로 리소스간의 연관성을 반환하는 유형의 질의 처리에 대해서는 충분히 고려하지 않고 있다. 본 논문에서는 시맨틱 연관성 검색 유형의 하나인 ${\rho}$-intersect 연산의 처리를 위한 인덱싱 및 질의 처리 방안을 소개한다. 이를 위해 접미사 배열을 이용한 인덱싱과 ${\rho}$-intersect 연산의 특징을 고려한 최적화 처리 방안을 제안한다. 실험적 성능 평가는 기존 기법에 비해 제안 기법의 평균 실행 시간이 3~7배의 빠른 질의 처리 성능을 보인다.

• 한국빅데이터학회지
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• 제5권1호
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• pp.65-75
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• 2020

본 연구에서는 정부의 포괄적 네거티브 규제 정책에 의해 선정된 부산 블록체인 규제자유특구의 활성화를 위한 정책방안을 제안하고자 한다. 우리나라는 유럽이나 미국과는 달리 포지티브 규제 기반으로, 활성화가 아닌, 억제를 목적으로 하므로 경제·산업 분야에서 지속적인 개혁 대상으로 취급된다. 문재인 정부는 이러한 포지티브 규제의 문제점을 해소하기 위한 획기적인 규제 혁신 정책으로 '포괄적 네거티브 규제'로의 전환을 제시하였다. 이에 대한 실행 방안으로 규제자유특구법에 기초한 신산업 육성을 위한 1단계 규제자유특구 7곳을 우선 선정하였다. 부산시는 '블록체인 규제자유특구'로 최종 선정되었으며, 블록체인을 바탕으로 침체된 지역경제를 활성화할 기회를 확보하였다. 본 연구는 부산 블록체인 규제자유특구의 활성화를 위한 정책 연구로, 규제자유특구에서 사업화할 수 있는 부산 특화 블록체인 서비스 발굴과 함께 산업 생태계 조성을 위한 방안을 제안하고자 하였다.

• 대한전자공학회논문지TC
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• 제45권12호
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• pp.58-65
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• 2008

본 논문에서는 MANET(Mobile Ad hoc Network)에서 가상 위치 기반 라우팅을 위한 GDHT(Geographic Distributed Hash Table)를 적용하는 방법을 제안한다. 기존의 GDHT는 저장하고자할 데이터를 가상 2차원 직교좌표계에 균일하게 매핑 하였다. 그러나, 위치 기반 라우팅을 사용하는 네트워크에서 노드의 분포는 기존 GDHT의 가상 공간과 다르게 분포한다. 따라서, 기존의 GDHT를 바로 적용할 경우, 많은 데이터들이 네트워크의 외곽 또는 특정 노드에 위치하게 된다. 이는 데이터 또는 서비스 검색 거리 및 시간을 늘리는 문제를 발생시킨다. 또한, BVR(Beacon Vector Routing)이나 LCR(Logical Coordinate Routing) 좌표 요소 사이에는 서로 연관관계가 있기 때문에 일반적인 해쉬 함수를 적용할 경우, 존재할 수 없는 좌표에 매핑 될 가능성이 높아진다. 이러한 문제를 해결하기 위하여, 데이터들의 분포를 제어할 수 있도록 하고 좌표 요소 사이의 연관관계가 반영될 수 있는 "Geographic 해쉬 함수"를 제안한다. 분석과 시뮬레이션을 통하여 제안하는 방법이 데이터 분포를 제어할 수 있고, 데이터 검색 성능을 향상시킴을 보인다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제6권1호
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• pp.406-425
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• 2012

Deploying advanced home networking technologies and modern home-networked devices in residential environments provides a playground for new home applications and services. Because home multimedia entertainment is among the most essential home applications, this paper presents an appealing home media content sharing scenario: home-networked devices can discover neighboring devices and share local media content, as well as enormous amounts of Internet media content in a convenient and networked manner. This ideal scenario differs from traditional usages that merely offer local media content and require tedious manual operations of connection setup and file transfer among various devices. To achieve this goal, this study proposes a proxy gateway architecture for home multimedia content distribution. The proposed architecture integrates several functional mechanisms, including UPnP-based device discovery, home gateway, Internet media provision, and in-home media content delivery. This design addresses several inherent limitations of device heterogeneity and network interoperability on home and public networks, and allows diverse home-networked devices to play media content in an identical and networked manner. Prototypical implementation of the proposed proxy gateway architecture develops a proof-of-concept software, integrating a BitTorrent peer-to-peer client, a UPnP protocol stack, and a UPnP AV media server, as well as media distribution and management components on the OSGi home gateway platform. Practical demonstration shows the proposed design and scenario realization, offering users an unlimited volume of media content for home multimedia entertainment.

• 대한한방내과학회지
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• 제40권3호
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• pp.295-311
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• 2019

Objectives: This research aimed to investigate Chinese clinical studies on the treatment of central post-stroke pain (CPSP) and thalamic syndrome after stroke with traditional herbal medicine (THM). Methods: Randomized controlled trials verifying the effects of herbal medicine on treating CPSP and thalamic syndrome after stroke were included in the study. Electrical and hand search were conducted in the China National Knowledge Infrastructure (CNKI), National Discovery for Science Leaders (NDSL), Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (Oasis) for CPSP and thalamic syndrome after stroke. A literature search was performed in the Chinese and Korean databases for papers published from January 1, 2010 to October 1, 2018. The selected literature was assessed by Cochrane's risk of bias. Results: Twelve reports on randomized controlled trials met the inclusion criteria from the 227 identified reports. Effective rate, comparison of visual analogy scale, present pain intensity, pain grading index, recurrence rate, follow-up, and a 36-item short form survey instrument were used to evaluate the treatments. The effective rate of the treatment group was significantly higher than that of the control group in all papers. Side effects occurred less frequently in the treatment group than in the western medicine control group. Conclusions: The treatment of CPSP and thalamic syndrome after stroke with THM was shown to be highly effective. Additional well-designed clinical trials are needed. This study can be used as a basis for further research on the treatment of CPSP and thalamic syndrome after stroke.

• 대한한방내과학회지
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• 제39권6호
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• pp.1105-1115
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• 2018

Objectives: The aim of this review is to investigate clinical studies on Oriental medicine treatment for aphasia after cerebrovascular disease. Methods: Using the keywords 'Aphasia', 'Oriental medicine', 'Stroke' 'Cerebral infarction', 'Cerebral hemorrhage', and 'Clinic', we searched domestic databases, including "NDSL (National Discovery for Science Leaders)", "Korean Traditional Knowledge Portal", "OASIS (Oriental Medicine Advanced Searching Integrated System)", and "RISS (Research Information Sharing Service)". Each keyword was not searched individually, but combined in various ways. To investigate recent trends, we limited our search to papers published after 2000. Papers that did not include a specific treatment method or did not match the subject "Aphasia after stroke" were excluded. Results: Using the searching method, 13 studies were found. Of these, 12 studies were in the form of case reports, while one was in the form of a non-randomized controlled trial. These studies showed positive results for the use of Oriental medicine in terms of the Korean version of the Western Aphasia Battery (K-WAB), the evaluation form on functional performance capability and accuracy of articulatory organs developed by Lee, aphasia screening test refered in 'Assessment in Speech-Language Pathology' and adapted properly to Korean, the Communicative Ability in Daily Living Test (CADLT), the Korean Version-Boston Naming Test (K-BNT), and language assessment items included in CNS, and NIHSS. Conclusions: Of the 12 case reports, 11 studies showed positive results of the use of Oriental medicine for treatment of aphasia after cerebrovascular disease. However, more sophisticated and large-scale clinical research on aphasia should be conducted.

• 대한한방내과학회지
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• 제40권4호
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• pp.612-628
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• 2019

Objective: The aim of this review was to investigate clinical studies on Korean medical treatments for dysmenorrhea. Method: Using the keywords "dysmenorrhea," "Korean medical treatment," "acupuncture," and "herbal medicine," searches were conducted using domestic databases, including the National Discovery for Science Leaders (NDSL), the Research Information Sharing Service(RISS), and the Oriental Medicine Advanced Searching Integrated System (OASIS). The keywords were combined in various ways, instead of being searched individually. Papers that did not cover clinical studies or were not matched with the subject, absent of the abstract and text, were excluded. Results: Using the above searching method, 20 studies were found. Of these, 15 were in the form of case reports and five were in the form of randomized controlled trials. Acupuncture, herb medicine, pharmacopuncture, moxibustion, and cupping were used as treatments for dysmenorrhea. All of these studies reported that the Korean medical treatment was effective. Conclusion: According to the results, Korean medical treatments can provide an effective treatment for dysmenorrhea. However, more clinical studies on dysmenorrhea should be conducted for further clinical applications.

• 산업경영시스템학회지
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• 제44권1호
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• pp.60-70
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• 2021

Recently, with the development of technologies for the fourth industrial revolution, convergence and complex technology are being applied to aircraft, electronic home appliances and mobile devices, and the number of parts used is increasing. Increasing the number of parts and the application of convergence technologies such as HW (hardware) and SW (software) are increasing the No Defect Found (NDF) phenomenon in which the defect is not reproduced or the cause of the defect cannot be identified in the subsequent investigation systems after the discovery of the defect in the product. The NDF phenomenon is a major problem when dealing with complex technical systems, and its consequences may be manifested in decreased safety and dependability and increased life cycle costs. Until now, NDF-related prior studies have been mainly focused on the NDF cost estimation, the cause and impact analysis of NDF in qualitative terms. And there have been no specific methodologies or examples of a working-level perspective to reduce NDF. The purpose of this study is to present a practical methodology for reducing NDF phenomena through data mining methods using quantitative data accumulated in the enterprise. In this study, we performed a cluster analysis using market defects and design-related variables of mobile devices. And then, by analyzing the characteristics of groups with high NDF ratios, we presented improvement directions in terms of design and after service policies. This is significant in solving NDF problems from a practical perspective in the company.

• BMB Reports
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• 제55권11호
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• pp.547-552
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• 2022

Sorafenib, originally identified as an inhibitor of multiple oncogenic kinases, induces ferroptosis in hepatocellular carcinoma (HCC) cells. Several pathways that mitigate sorafenib-induced ferroptosis confer drug resistance; thus strategies that enhance ferroptosis increase sorafenib efficacy. Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is upregulated in human HCC tissues and plays a role in cancer cell proliferation. The aim of this study was to determine whether inhibition of ERRγ with DN200434, an orally available inverse agonist, can overcome resistance to sorafenib through induction of ferroptosis. Sorafenib-resistant HCC cells were less sensitive to sorafenibinduced ferroptosis and showed significantly higher ERRγ levels than sorafenib-sensitive HCC cells. DN200434 induced lipid peroxidation and ferroptosis in sorafenib-resistant HCC cells. Mechanistically, DN200434 increased mitochondrial ROS generation by reducing glutathione/glutathione disulfide levels, which subsequently reduced mTOR activity and GPX4 levels. DN200434 induced amplification of the antitumor effects of sorafenib was confirmed in a tumor xenograft model. The present results indicate that DN200434 may be a novel therapeutic strategy to re-sensitize HCC cells to sorafenib.

• 한국소프트웨어감정평가학회 논문지
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• 제16권2호
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• pp.77-85
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• 2020

본 논문에서는 스마트 계약의 핵심 기술로 사용되는 분산원장 기술의 운영과 분산원장 기술의 구성요소에 대하여 연구하고 분산원장의 요소기술을 차세대 만물네트워크에 적용하기 위한 해결책으로 현재 ISO/IEC JTC1 SC6에서 표준화가 진행 중인 만물네트워크 프로토콜의 사물유저 소셜 그룹 관리 기능을 이용한 분산원장 기술의 프로토콜을 제시하였다. 만물네트워크의 사물유저 소셜 그룹 관리 기능은 안정적인 프로토콜 기능과 데이터 전송 관리를 제공하고 있으며 멤버 디스커버리기능, 데이터 전송 통로 관리기능 등의 그룹 관리 기능을 제공하고 있다. 분산원장 요소 기술을 상호 합의로 적용할 수 있는 서비스를 제공할 수 있어서 분산원장 노드들의 그룹 관리 기능에 도움이 될 것으로 예상하며 표준화가 진행되고 있는 ISO/IEC JTC1 SC6의 미래 네트워크 기능과 구조에 적극 반영하고자 한다.