• Title/Summary/Keyword: Series Expansion

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Clinical Factors and Perioperative Strategies Associated with Outcome in Preinjury Antiplatelet and Anticoagulation Therapy for Patients with Traumatic Brain Injuries

  • Pang, Chang Hwan;Lee, Soo Eon;Yoo, Heon
    • Journal of Korean Neurosurgical Society
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    • v.58 no.3
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    • pp.262-270
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    • 2015
  • Objective : Long-term oral anticoagulation or antiplatelet therapy has been used with increasing frequency in the elderly. These patients are at increased risk of morbidity and mortality from expansion of intracranial hemorrhage. We conducted a single-center retrospective case control study to evaluate risk factors associated with outcomes and to identify the differences in outcome in traumatic brain injury between preinjury anticoagulation use and without anticoagulation. Methods : A retrospective study of patients who underwent craniotomy or craniectomy for acute traumatic cerebral hemorrhage, between January 2005 and December 2014 was performed. Results : A consecutive series of 50 patients were evaluated. The factors significantly differed between the two groups were initial Prothrombin Time-International Normalized Ratio, initial platelet count, initial Glasgow Coma Scale score, and postoperative intracranial bleeding. Mean Glasgow Outcome Scale (GOS) score were similar between the two groups. In the patient with low-energy trauma only, no significant differences in GOS score, postoperative bleeding and many other factors were observed. The contributing factors to postoperative bleeding was preinjury anticoagulation and its adjusted odds ratio was 12 [adjusted odds ratio (OR), 12.242; p=0.0070]. The contributing factors to low GOS scores, which mean unfavorable neurological outcomes, were age (adjusted OR, 1.073; p=0.039) and Rotterdam scale score for CT scans (adjusted OR, 3.123; p=0.0020). Conclusion : Preinjury anticoagulation therapy contributed significantly to the occurrence of postoperative bleeding. However, preinjury anticoagulation therapy in the patients with low-energy trauma did not contribute to the poor clinical outcomes or total hospital stay. Careful attention should be given to older patients and severity of hemorrhage on initial brain CT.

Weighted Integral Method for an Estimation of Displacement COV of Laminated Composite Plates (복합적층판의 변위 변동계수 산정을 위한 가중적분법)

  • Noh, Hyuk-Chun
    • Journal of the Korean Society for Advanced Composite Structures
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    • v.1 no.2
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    • pp.29-35
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    • 2010
  • In addition to the Young's modulus, the Poisson's ratio is also at the center of attention in the field stochastic finite element analysis since the parameters play an important role in determining structural behavior. Accordingly, the sole effect of this parameter on the response variability is of importance from the perspective of estimation of uncertain response. To this end, a formulation to determine the response variability in laminate composite plates due to the spatial randomness of Poisson's ratio is suggested. The independent contributions of random Poisson's ratiocan be captured in terms of sub-matrices which include the effect of the random parameter in the same order, which can be attained by using the Taylor's series expansion about the mean of the parameter. In order to validate the adequacy of the proposed formulation, several example analyses are performed, and then the results are compared with Monte Carlo simulation (MCS). A good agreement between the suggested scheme and MCS is observed showing the adequacy of the scheme.

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Development of a numerical modelling technique for evaluation of a long-term chemical deterioration of tunnel shotcrete lining (터널 숏크리트 라이닝의 장기 화학적 열화 손상 평가를 위한 수치 모델링 기법 개발)

  • Shin, Hyu-Soung;Kim, Dong-Gyou
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.9 no.3
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    • pp.299-307
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    • 2007
  • In this study, a new concept for simulating a physical damage of tunnel shotcrete lining due to a long-term chemical deterioration has been proposed. It is known that the damage takes place mainly by internal cracks, reduction of stiffness and strength, which results mainly from volume expansion of the lining and corrosion of cement materials, respectively. This damage mechanism of shotcrete lining appears similar in most kinds of chemical reactions in tunnels. Therefore, the mechanical deterioration mechanism induced by a series of chemical reactions was generalized in this study and mathematically formulated in the framework of thermodynamics. The numerical model was implemented to a 3D finite element code, which can be used to simulate behaviour of tunnel structures undergoing external loads as well as chemical deterioration in time. A number of illustrative examples were given to show a feasibility of the model in tunnel designs.

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Measuring impac of electronic publications on scholarly communication using bibliometric analysis (전자출판물의 확산에 따른 학술커뮤니케이션 변화의 계량서지학적 분석)

  • Shin, Eun-Ja
    • Journal of the Korean Society for information Management
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    • v.20 no.3
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    • pp.31-49
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    • 2003
  • Electronic publications, including e-journals, show a rapid expansion due to its several advantages for the academic and research community. The purpose of this study is to analyze the impact of e-journals on scholarly communication. The impact factors and immediacy indices were provided via JCR social science edition have been used to conduct a series of analysis on three subject fields, economics, law and psychology. The data from the last eight years show that the impact factors of e-journals have not changed, but immediacy indices have intensely increased in recent two years. Significant increase of immediacy indices is probably due to prevalence of e-journals or electronic sources of articles. The result reveals that e-journals play an important role in speeding up the scholarly communication. It is expected that the findings of this study can contribute to more efficient management of the digital libraries.

A Comparative Coagulopathic Study for Treatment of Vasospasm by Using Low- and High-molecular Weight Hydroxyethyl Starches

  • Hwang, Sung-Ho;Won, Yu-Sam;Yu, Jang-Sun;Yang, Jae-Young;Choi, Chun-Sik
    • Journal of Korean Neurosurgical Society
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    • v.42 no.5
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    • pp.377-381
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    • 2007
  • Objective : High-molecular-weight hydroxyethyl starch (HES) compromises blood coagulation more than does low-molecular-weight HES. We compared the effects of low- and high-molecular-weight HES for the treatment of vasospasm and investigated the dose relationship with each other. Methods : Retrospectively, in a series of consecutive 102 patients with subarachnoid hemorrhage (SAH), 35 patients developed clinical symptoms of vasospasm of these fourteen patients were treated with low-molecular weight HES for volume expansion while the other 21 received high-molecular-weight HES as continuous intravenous infusion. Prothrombin time (PT), partial thromboplastin time (PIT), fibrinogen level, and platelet count were all measured prior to initiation, during treatment and after termination of therapy for symptomatic vasospasm. The total dose of HES ranged from 5 L to 14 L and median infusion duration was 10 days. Results : A more pronounced PTT prolongation was observed in high-molecular-weight HES group compared with low-molecular-weight HES group. No other coagulation parameters were altered. Dosage (=duration) shows a positive correlation with PTT. Clinically, significant bleeding episodes were noted in four patients who received high-molecular-weight HES. Conclusion : Coagulopathy was developed in direct proportion to molecular weight of starch and dosages. We propose the extreme caution in the administration of HES solution for the vasospasm treatment.

Studies on the Cycle Simulation for a Geothermal Heat Pump System using CO2 as Refrigerant (CO2 지열 히트펌프 사이클 모사에 관한 연구)

  • Kim, Young-Jae;Chang, Keun-Sun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.6
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    • pp.2888-2897
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    • 2011
  • The performance of a geothermal heat pump system using carbon dioxide was investigated by the steady-state cycle simulation program developed in this study. A parametric study was carried out in order to investigate the effect of various operating conditions on the performance of the basic cycle without an IHX(internal heat exchanger). The simulation program consists of several Fortran subroutines for simulating indoor and outdoor heat exchangers, compressors, and expansion valves and Visual Basic subroutines for the graphic user interface(GUI) consisted with pre-processor for input data and post-processor for the output data. Refprop V6.01 was used for estimating the thermodynamic properties and equilibrium behaviors of carbon dioxide. The simulation results were validated by comparing experimental data through a series of case studies. The cycle simulation program developed in this work would seem to be a useful tool in optimizing and establishing economical and efficient operating conditions in the $CO_2$ geothermal heat pump system.

Facet Query Expansion with an Object-Based Thesaurus in Reusable Component Retrieval Systems (재사용 부품 검색 시스템에서 객체기반 시소러스를 이용한 패싯 질의의 확장)

  • Choi, Jae-Hun;Kim, Ki-Heon;Yang, Jae-Dong;Lee, Dong-Gil
    • Journal of KIISE:Software and Applications
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    • v.27 no.2
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    • pp.168-179
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    • 2000
  • In reusable component retrieval systems with facet-based schemes, facet queries are generally used for representing the characteristics of components relevant to users. This paper proposes an expanded facet query equipped with an object-based thesaurus to precisely formulate user's intents. To evaluate the query, a component retrieval system is also designed and implemented. For exactly retrieving the components, user's query should include relevant facet values capable of fully specifying their characteristics. However, simply listing a series of facet values directly inputted by users, conventional queries fails to precisely represent user's intents. Our query, called expanded facet query, employs fuzzy boolean operators and object-based thesaurus; the former logically expresses the fuzzy connectives between facet queries and required components, whereas the latter helps users appropriately select the specific facet values into the query. A thesaurus query is provided to recommend the relevant facet values with their fuzzy degrees from the thesaurus as well. Furthermore, our retrieval system can automatically formulate queries with the recommended facet values, if necessary.

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Ice cliff retreat and sea-ice formation observed around King Sejong Station in King George Island, West Antarctica (세종기지 주변에서 관찰된 빙벽 후퇴와 바다 결빙)

  • Chung, Ho-Sung;Lee, Bang-Yong;Chang, Soon-Keun;Kim, Ji-Hee;Kim, Yea-Dong
    • Ocean and Polar Research
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    • v.26 no.1
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    • pp.1-10
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    • 2004
  • Ice cliff retreat and sea-ice formation around King Sejong Station in King George Island were analysed and compared with air temperature change. Analysis of 33-year (1969-2001) air temperature records at Bellingshausen Station has revealed regional atmospheric warming, and the increasing rate of air temperature Is equivalent to a warming of $1^{\circ}C$ for 27-year period. Here we present time-series of observations for the areal extent of the ice cliff and ice sheet, showing that they have retreated dramatically in the past 45 years (1956-2001). Retreat of 1,050 m in length of the ice clifr has changed the Marian Cove into a low rectangular form of 4 km in length and 1 to 1.3km in width. The retreat rates have since increased from 6 m/yr of the Primary investigated Period to 54 and 81m/yr in the recent years. Exceptionally, the ice cliff had been advanced of 21m in length for a year between 1987 and 1988 of cold winters. Ice sheet in King George Island also shows a similar decrease, and the decreasing extent is much larger at the southern part of the Main Cove, relatively more exposed to the sun, than at the northern part. Comparing sea-ice formation in winter with air temperature data shows a pattern starting to freeze below $-5^{\circ}C$ and to thaw over $-3^{\circ}C$. It is conclusively estimated that the patterns and magnitudes of ice cliff retreat and sea-ice formation are consistent with fluctuations of the air temperature, and that the recent rapid retreat of ice cliff and less formation of sea-ice are caused especially by the warming trends in autumn accompanied with expansion of summer thawing period.

The Performance of a Horizontal Flexible Membrane Breakwater in Waves (파랑중 수평형 유연막 방파제 성능해석)

  • Cho I.H.;Hong S.W.;Kim M.H.
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.1 no.2
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    • pp.27-39
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    • 1998
  • The interaction of monochromatic incident waves with a horizontal flexible membrane is investigated in the context of two-dimensional linear hydro-elastic theory. First, analytic diffraction and radiation solutions for a submerged impermeable horizontal membrane are obtained. Second, the theoretical prediction was compared with a series of experiments conducted in a two-dimensional wave tank at Texas A&M University. The measured reflection and transmission coefficients reasonably follow the trend of predicted values. Using the developed computer program, the performance of surface-mounted or submerged horizontal membrane wave barriers is tested with various system parameters and wave characteristics. It is found that the properly designed horizontal flexible membrane can be an effective wave barrier.

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Osteoplasty in Acute Vertebral Burst Fractures

  • Park, Sang-Kyu;Bak, Koang-Hum;Cheong, Jin-Hwan;Kim, Jae-Min;Kim, Choong-Hyun
    • Journal of Korean Neurosurgical Society
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    • v.40 no.2
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    • pp.90-94
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    • 2006
  • Objective : Acute vertebral burst fractures warrant extensive fixation and fusion on the spine. Osteoplasty [vertebroplasty with high density resin without vertebral expansion] has been used to treat osteoporotic vertebral compression fractures. We report our experiences with osteoplasty in acute vertebral burst fractures. Methods : Twenty-eight cases of acute vertebral burst fracture were operated with osteoplasty. Eighteen patients had osteoporosis concurrently. Preoperative MRI was performed in all cases to find fracture level and to evaluate the severity of injury. Preoperative CT revealed burst fracture in the series. The patients with severe ligament injury or spinal canal compromise were excluded from indication. Osteoplasty was performed under local anesthesia and high density polymethylmethacrylate[PMMA] was injected carefully avoiding cement leakage into spinal canal. The procedure was performed unilaterally in 21 cases and bilaterally in 7 cases. The patients were allowed to ambulate right after surgery. Most patients discharged within 5 days and followed up at least 6 months. Results : There were 12 men and 16 women with average age of 45.3[28-82]. Five patients had 2 level fractures and 2 patients had 3 level fractures. The average injection volume was 5.6cc per level Average VAS [Visual Analogue Scale] improved 26mm after surgery. The immediate postoperative X-ray showed 2 cases of filler spillage into spinal canal and 4 cases of leakage into the retroperitoneal space. One patient with intraspinal leakage was underwent the laminectomy to remove the resin. Conclusion : Osteoplasty is a safe and new treatment option in the burst fractures. Osteoplasty with minimally invasive technique reduced the hospital stay and recovery time in vertebral fracture patients.