• 통합자연과학논문집
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• 제5권2호
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• pp.65-71
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• 2012

Neuropeptide Y (NPY), a 36-amino acid polypeptide, is a member of the pancreatic polypeptide family, which consists of NPY, peptide YY (PYY) and pancreatic polypeptide (PP). The neuropeptide Y (NPY) receptors called Y receptors belongs to G-protein coupled that are involved in a variety of physiological functions such as appetite regulation, circadian rhythm and anxiety. Five receptor subtypes have been cloned in mammals (Y1, Y2, Y4, Y5, and Y6) of which four are functional. In this short review, information about the functional NYP receptors was analyzed. Sequence analyses were done between these receptors to identify the relationships between them. Phylogram was generated between these receptors to identify the close homologue between these receptors. Our sequence analyses found that Y1 and Y4 receptors are close than the other receptors. Further structure based analysis could be useful to identify subtype selective antagonists and dual antagonists targeting Y1 and Y4 receptors.

• 대한한의학원전학회지
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• 제20권4호
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• pp.119-126
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• 2007

The biological and pathological states of lung, spleen, liver and kidneys are determined by nature and emotion of sorrow, anger, joy and pleasure, It is considered that the music, besides medicine or acupuncture, can be a way of treating as a therapeutics for the treatment of Sasangin's diseases. This study is to find out a way of music therapy for the treatment of Sasangin's diseases. The ways of music therapy in each constitution based on 'the great and small of Viscera and Bowels' and 'the exhale and inhale, the drawing in and sending out' are as follows: 1. In case of Soeumin, a skip going up melodic progression, dotted rhythm and the major triad harmonic progression are recommended to improve the Qi of warm Yang. 2. In case of Soyangin, in regular sequence down melodic progression, a sixteenth note and the minor triad harmonic progression are recommended to improve the Qi of cool Yin. 3. In case of Taeumin, in regular sequence going up melodic progression, a sixteenth note and the bright and active the major triad harmonic progression are recommended to improve the Qi of dispersing exhale. 4. In case of Taeyangin, a skip down melodic progression, a quarter note and a diminished triad harmonic progression are recommended to improve the Qi of gathering inhale.

• 대한약침학회지
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• 제26권3호
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• pp.276-284
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• 2023

Objectives: Previous studies have shown that anger can lead to frontal lobe α (8-13 Hz) band asymmetry (FAA) in electroencephalogram (EEG), in accordance with motivational direction. This pilot study aimed to investigate the impact of acupuncture on FAA elicited by anger. Methods: Thirty-four right-handed participants scoring above 75 points on the Novaco Anger Scale were included. Baseline EEG signals were recorded for eight minutes using a 32-channel cap under comfortable conditions. Anger was induced through a nine-minute sequence of Articulated Thoughts in Simulated Situations (ATSS) task. Following that, participants received acupuncture at GB20 and GB21 for 10 minutes. Fast Fourier transform was employed for frequency analysis, and repeated measure ANOVA was conducted for statistical analysis. Results: The results revealed that participants exhibited significantly higher FAA (p = 0.026), particularly in the left hemisphere, after the ATSS task sequence compared to the baseline. During acupuncture treatment, the greater left-sided FAA was significantly reduced (p = 0.027) and reversed. Upon the cessation of acupuncture, FAA returned to a value between the baseline and the anger-evoked stage (p = 0.046). Conclusion: The EEG results of this study revealed that anger stimulation induced an increase in left-sided FAA, which was effectively alleviated by acupuncture. This led to an immediate restoration of FAA asymmetry induced by anger. These findings suggest the potential of acupuncture as a treatment option for reducing FAA associated with anger.

• Journal of Photoscience
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• 제9권2호
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• pp.17-20
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• 2002

We have cloned a cDNA for an opsin (Boceropsin) from the silkworm larval brain which was suggested to contain the photoperiodic receptor. Its deduced amino acid sequence was composed of 381 amino acids and included amino acid residues highly conserved in insect visual pigments. This opsin belonged to the long wavelength photoreceptor group of insect opsins, and are presumed to be photoperiodic receptor. RT-PCR analysis revealed that Boceropsin mRNA is expressed in the larval brain, but not in the subesophageal (Sg) and thoracic ganglion. Immunohistochemical analyses demonstrated that Boceropsin protein is present bilaterally in some defined cells localized in the brain of the Bombyx larva. Boceropsin was considered not to be involved in the circadian photoreception, because carotenoids are not indispensable for the photoreception and formation of circadian rhythms in the silkworm.

• 한국환경과학회지
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• 제12권4호
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• pp.383-391
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• 2003

The purpose of this research explain the meaning of the environmental design principles and cultural landscape pattern(dualistic space organization) of the Hahoe(河回:winding river village) the Yangdong(良洞) traditional village. Village's space organizations based on Shamanism, fin-yang and Five elements principle, Feng-shui idea, social system and Confucian ideas. And it were accomplish curat landscape pattern(village:form+object=pattern) through the frame of settlement space. As a central persons of villages(the Hahoe $.$ the Yangdong) construction, Suhae(西厓) experienced tough Chunghyodang - Wonjichongsa - Ogyonchongsa - Pyongsansowon channel(忠孝堂 -遠志精舍 -玉端精含 -脣山書院) and Kyomam(謙 ) experienced tough Yangjindang - Binyeonchongsa - Kyomamchongsa - Hwachonsodang(養眞堂 - 賓淵精舍 - 謙庵f精舍 - 花川書堂) channel. Also Woojae(愚齋) experienced tough Suhbackdang - Khankachung - Dongkangsowon(書百堂 - 觀稼停 - 東江書院) and Hoejae(晦齋) experienced tough Moochumdang - Hyangdan - Oaksansowon(無添堂 - 香壇 - 玉山書院). It is space organization of themselves interact contrast and sequence principles with competition in good faith. And ecological art-space, that is, environmental spare organizations of traditional village has been reflected harmony between nature and artificiality, spatial rhythm and sequence, spatial hierarchy between upper classes and humble class, permeability space, asymmetrical balance, aesthetic space perception. The humble classes hold a ceremony Hahoe's Pyolsingut-Talnori(maskdance drama), Dangjae(堂祭:religious service) at the Dang(堂:shamanism spot) and Yangdong's Sohraesulnori, Hohminori. And the upper class hold a ceremony Hahoe's Julbulnori and Yangdong's Chungjanori connected with culture of confucianism. Specially, the cultural structure cf the village is evidence of a contrast between the upper class and the humble classes, time, method and location of ceremony(performance).

• 한국실내디자인학회논문집
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• 제23권2호
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• pp.108-116
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• 2014

This study is based on the arguments of Sofia Sarah and concept of 'Sequence Narrative' of Nigel Coates, the founder of Nato. Specifically, this study was conducted under the premise that narrative exhibition space will affect the engagement of viewers. As a result of this study, a method of analyzing a science museum's exhibition space was presented using the narrative structure and the following attributes of visuals: sequence of viewing; spatial tension; spatial pace. The findings are as follows. In terms of 'spatial tension', the exhibiton space with the following progression was more likely to provide viewers with in-depth experience: 'raise of tension' - 'change of pace' - detente.' Although the limited sample doesn't lead to verification of the analysis method and conclusion of its significance, the following was clearly revealed: Exhibiton space that utilizes the structure and attributes of a narrative that provides progression and dramatic tension, as if the viewers were watching a film, is more likely to offer in-depth experience than other spaces. In terms of 'phase transition', the following was revealed: Pace variation around the space with the strongest spatial tension could affect the concentration and engagement of viewers. It suggests the following fact: Spatial rhythm and speed variation in the area with the strongest visual emphasis encourage viewers to feel the spatial changes, maintain their concentration, and continue their viewing.

• Journal of Pharmaceutical Investigation
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• 제27권3호
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• pp.181-187
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• 1997

The purpose of this work was to investigate pharmacokinetics of alcohol as a function of dose and time of administration of ethanol. The pharmacokinetics of alcohol 15 min after and before oral administration of aspartate-containing compositions to rats were also evaluated. The retention time of acetaldehyde, alcohol and isopropyl alcohol an internal standard in gas chromatogram was 3.6, 6.0 and 10.5 min, respectively. The maximum concentration of alcohol $(C_{max})$ and area under the blood concentration (AUC) were significanly increased as a function of ethanol dose in a nonlinear fashion. The significant diurnal variation of alcohol pharmacokinetics was also noted, showing fast metabolism and elimination when given orally in the night time. When APAP was given after administration alcohol (1g/kg) to rats, AUC and $C_{max}$ were increased when compared to alcohol only. However, AUC and $C_{max}$ were decreased when aspartate or standard complex compositions containing aceaminophen (APAP, 250mg). sodium L-aspartate(25 mg), dl-methionine (125 mg) and anhydrous caffeine (25 mg) was orally given by coupling malate/asparate shuttle in hepatocyte. The blood alcohol concentration profiles between aspartate and standard complex compositions were similar when given before or after administration alcohol (1g/kg) to rats. No significant difference of administration sequence was observed. However, it was noted that AUC and $C_{max}$ of standard complex compositions given before alcohol administration were significantly lower when compared with alcohol only. Based on these findings, dose, time of administration and composition of drugs to improve alcohol metabolism and elimination were considered to be important in the pharmacokinetics of alcohol. The administration sequence of drug compositions and alcohol might be also considerd.

• BMB Reports
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• 제41권8호
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• pp.587-592
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• 2008

Cotesia vestalis is an endoparasitoid of Plutella xylostella larvae and injects a polydnavirus (CvBV) into its host during oviposition. In this report we characterize the gene, CvBV3307, and its products. CvBV3307 is located on segment S33 of the CvBV genome, is 517 bp, and encodes a putative protein of 122 amino acids, including a serine-rich region. The expression pattern of CvBV3307 in parasitized larvae and the subcellular localization of CvBV3307 only in granulocytes indicated that it might be involved in early protection of parasitoid eggs from host cellular encapsulation and in manipulating the hormone titer and developmental rhythm of host larvae. Western blot analysis showed that the size of the immunoreactive protein (about 55 kDa) in parasitized hosts at 48 hours post parasitization (h p.p.) is much larger than the predicted molecular weight of 13.6 kDa, which suggests that CvBV3307 undergoes extensive post-translational modification in hosts.

• 정보처리학회논문지D
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• 제14D권4호
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• pp.381-388
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• 2007

데이터 전송 기술의 발달과 디지털 기기의 다양한 보급으로 소비자들은 디지털 콘텐츠를 생산하는 주체로 변화하였다. 생성되는 다양한 콘텐츠 중 사용자는 동영상 제작에 큰 관심을 보였으며, 그 중 음악과 사진으로 동영상을 제작하는 방법은 사용자에게 보다 손쉽게 동영상을 만들 수 있도록 제공되었다. 그러나 현재의 방법은 사진과 사진간의 연관성이 결여되었을 뿐 아니라, 음악의 리듬과 관계없이 일정 시간 간격에 따라 사진이 변화한다. 본 논문에서는 음악 분석을 통하여 음악 리듬에 따라 사진이 변화하고, 사진 분석을 통하여 사진 간의 연관성을 나타낼 수 있는 동영상 제작 방법을 제안한다. 음악 분석은 RMS를 이용하여 리듬이 강한 부분을 찾았으며, 사진 분석은 구조 단순도와 얼굴 영역 추출을 이용하여 인물 사진과 풍경사진으로 분류하였다. 사진 분석은 86.4%의 성공률을 보였으며, 이를 이용하여 음악 리듬에 맞은 사진 변화 위치와 사진간의 연관성을 가진 순서 배치를 할 수 있었다. 따라서 음악 분석과 사진 분석을 이용한 자연스럽고 효과적인 동영상을 제작 할 수 있다.

• 한국HCI학회:학술대회논문집
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• 한국HCI학회 2009년도 학술대회
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• pp.482-486
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• 2009

기존의 음악 플레이어들은 녹음 되거나 디지털적으로 캡쳐 된 음악정보를 재생 하여 사용자들이 "한 방향"으로의 수동적인 감상을 가능하게 하였다. 본 논문에서는 mp3나 wav 로 형태로 실제로 연주 되고 녹음 된 음악에서의 특정 음표의 시간적인 위치를 찾아내는 알고리즘을 소개 하도록 한다. 찾아내고자 하는 음표의 악보를 이용하면, 우선 주어진 녹음 된 음악 파일에서의 해당 음표의 위치를 시간적인 순서대로 예측 할 수 있다. 그러나, 연주/녹음된 음악은 악보에 나와 있는 대로 연주 되지 않고 대부분 시간적으로 혹은 심지어 내용적으로 변화가 있게 마련이다. 따라서 추가적인 분석을 통하여 음표의 정확한 위치를 찾아나가게 되고, 그 위치로부터 이러한 예측 및 교정작업 (prediction/correction)을 계속적으로 수행하게 된다. 이러한 부가적인 정보를 이용하여 사용자가 음표의 위치에 (즉 리듬에) 기반한 인터액션을 통하여 실제 음악을 연주하는 듯 한 사용자 경험을 줄 수 있다.