• Title/Summary/Keyword: Separation Line

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An Experimental Study on the Flow Around a Simplified 2-Dimensional Vehicle-Like body (단순화된 2차원 자동차형 물체주위의 유동에 관한 실험적 연구)

  • 유정열;김사량;강신형;백세진;이택시;김응서
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.13 no.1
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    • pp.178-189
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    • 1989
  • An experimental study has been performed to study the effect of the base slant angle of a 1/10 scale two-dimensional vehicle-like body on its wake flow including the recirculating region, where the simplified shape of the body has been originated from a profile of a domestic passenger car. In the case of a Reynolds number based on the length of the model R=7.96*10$^{5}$ , the surface pressure coefficient, the mean velocity and the turbulent stresses have been measured, while the flow visualization technique using wool tuft has been adopted as well. When the base slant angle of the model is 15.deg., the free stream flowing parallel to the slant is observed to be separated from the lower edge of the slant, thus forming the smallest recirculating region. When the base slant angles are 30.deg. and 45.deg., the free streams are separated from the upper edge of the slant and the sizes of the recirculating zones are observed to be almost the same as when the base slant angle is 0.deg. From these observations, it is conjectured that between the base slant angles of 15.deg. and 30.deg. there exists a critical angle at which the size of the recirculating region becomes minimum and as the slant angle becomes larger than this critical angle the separation line moves along the slant towards the rear edge of the roof. Through the flow visualization technique, the existence of the two counter-rotating bubbles in the recirculating region has been clearly observed and verified.

A study on separation and characterization of matrix metalloproteinase-9 inhibitors from natural plants (천연 식물 추출물에서 Matrix Metalloproteinase-9 활성 억제제의 분리 및 특성화에 관한 연구)

  • Hur, Yong-Chul;Park, Sung-Woo;Kim, Tai-Jin
    • Analytical Science and Technology
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    • v.18 no.3
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    • pp.188-193
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    • 2005
  • Three different oriental natural plants (Angelicae Dahuricae Radix, Sanguisorba Officinalis L, Euonymus alatus) were extracted with 70% methanol under refluxing for 4 hr in order to investigate their inhibitory effect on Matrix Metalloproteinase-9 (MMP-9) by a modified gelatin zymography, where only euonymus alatus showed the inhibitory effect on the activity of Matrix MMP-9. The fraction was collected by using the mixture of ethyl acetate and hexane on silica gel column. Seven portions were obtained and three fractions of them (first, third and forth) showed inhibitory effect on the zymography. To verify the effect of these substances on cells, human hepatoma, Hep3B cells as a cancer model, and Chang liver cells as a normal model were selected. In order to examine the cell viability, $1{\mu}g/mL$ of each extract was treated on cells. Most of the methanol soluble fractions showed negligible toxicity on human liver cell line.

Real-time monitoring of net setting and hauling process in fishing operations of Danish seine vessel using ECDIS (ECDIS에 의한 외끌이 기선저인망 어선의 투양망 조업 과정의 실시간 모니터링)

  • Lee, Dae-Jae;Byun, Duck-Soo
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.43 no.4
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    • pp.347-354
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    • 2007
  • This paper describes on the real-time monitoring of net setting and hauling process for fishing operations of Danish seine vessels in the southern waters of Korea as an application of a PC based ECDIS system. Tracking of fishing process was performed for the large scale Danish seine vessel of G/T 90 and 350 PS class using the fishing gear which the length of net, ground rope, head rope and sweep line including warp in both sides were 86m, 104m, 118m and 3,200m, respectively. Tracking information for net setting and hauling process was continuously recorded for 23 fishing operations performed on November and December, 2003. All measurement data, such as trawl position, heading, towing course and past track which was individually time stamped during data acquisition, was processed in real time on the ECDIS and displayed simultaneously on the ENC chart. The results indicated that after the separation of a marker buoy from Danish seiner, the averaged running speed of vessel and the averaged setting period while shooting the seine on the course of diamond shape to surround the fish school in the 23 fishing operations were 8.3 knots and 13.1 minutes, respectively. And with the maker buoy taken on board, the averaged running speed of vessel and the averaged towing period while closing the seine on the straight route was 1.0 knots and 47.0 minutes, respectively. After the closing stage of hand rope, the hand rope was towed by the averaged speed of 2.2 knots during the 13.0 minutes. The average area for route of diamond shape swept by sweep lines of the seine in 23 fishing grounds was $709,951.6m^2$. Further investigation is also planed to provide more quantitative tracking information and to achieve more effective surveillance and control of Danish seine vessels in EEZ fishing grounds.

Effect of Phosphodiesterase in Regulating the Activity of Lysosomes in the HeLa Cell Line

  • Hong, Eun-Seon;Kim, Bit-Na;Kim, Yang-Hoon;Min, Jiho
    • Journal of Microbiology and Biotechnology
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    • v.27 no.2
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    • pp.372-379
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    • 2017
  • The transport of lysosomal enzymes into the lysosomes depends on the phosphorylation of their chains and the binding of the phosphorylated residues to mannose-6-phosphate receptors. The efficiency of separation depends more on the phosphodiesterases (PDEs) than on the activity of the phosphorylation of mannose residues and can be determined in vitro. PDEs play important roles in regulation of the activation of lysosomes. The expression of proteins was confirmed by western blotting. All PDE4 series protein expression was reduced in high concentrations of rolipram. As a result of observing the fluorescence intensity after rolipram treatment, the lysosomal enzyme was activated at low concentrations and suppressed at high concentrations. High concentrations of rolipram recovered the original function. Antimicrobial activity was not shown in either 10 or $100{\mu}M$ concentrations of rolipram in treated HeLa cells in vitro. However, the higher anticancer activity at lower rolipram concentration was shown in lysosomal enzyme treated with $10{\mu}M$ of rolipram. The anticancer activity was confirmed through cathepsin B and D assay. Tranfection allowed examination of the relationship between PDE4 and lysosomal activity in more detail. Protein expression was confirmed to be reduced. Fluorescence intensity showed decreased activity of lysosomes and ROS in cells transfected with the antisense sequences of PDE4 A, B, C, and D. PDE4A showed anticancer activity, whereas lysosome from cells transfected with the antisense sequences of PDE4 B, C, and D had decreased anticancer activity. These results showed the PDE4 A, B, C, and D are conjunctly related with lysosomal activity.

TREATMENT OF FUSED PERMANENT MANDIBULAR LATERAL AND CENTRAL INCISORS: REPORTS OF CASES (유합된 하악 영구 중절치와 측절치의 치료에 관한 증례보고)

  • Han, Jeong-Jae;Kim, Dae-Eop;Lee, Kwang-Hee
    • Journal of the korean academy of Pediatric Dentistry
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    • v.24 no.4
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    • pp.795-804
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    • 1997
  • Developmental dental morphological anomalies are fusion, gemination, twinning, concrescence and etc. They may cause many problems in conservative, periodontal and esthetic aspects. Fusion is a condition where two separate tooth buds unite at some stage in their development to form a bifid crown. If tooth contact occurs early, at least before the start of calcification, the two teeth may be completely unites to form a single large tooth. If tooth contact occurs after the time when a portion of the tooth crown has completed its formation, there may be union of the roots only. In fusion the dentin is always confluent. Fusion teeth is more common in the deciduous than in the permanent dentition. Fused teeth are relatively rare, and are mostly mandibular anterior teeth. Fusion of normal and supernumerary teeth or between normal teeth may occurs. The exact etiology factor of fusion is unknown, but genetic and environmental factors seems to be related. A variety of complications and subsequent treatments have been suggested on this teeth. Periodontal conditions may arise due to a groove formed at the line of fusion of the two teeth. Crowding or Protrusion with potential for malocclusion or delayed eruption of adjacent teeth. Fusion teeth appear in the anterior region, they usually cause esthetic problems. Treatments vary depending on the problem, the location, and the extent of fusion. Treatment of fused teeth has been reported from endodontic, orthodontic, periodontic, surgical and multidisciplinary. This report presents the esthetic improvements by separation of two clinical crowns. Bone reduction or endodontic treatments are not required.

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A Study on Combustion and Heat Transfer in Premixed Impinging Flames of Syngas(H2/CO)/Air Part II: Heat Transfer Characteristics (합성가스(H2/CO)/공기 예혼합 충돌화염의 연소 및 열전달 연구 Part II : 열전달 특성)

  • Sim, Keunseon;Jeong, Byeonggyu;Lee, Yongho;Lee, Keeman
    • Journal of Hydrogen and New Energy
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    • v.25 no.1
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    • pp.59-71
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    • 2014
  • An experimental study has been conducted to investigate the heat transfer characteristics of laminar syngas/air mixture with 10% hydrogen content impinging normally to a flat plate of cylinder. Effects of impinging distance, Reynolds number and equivalence ratio as major parameters on heat fluxes of stagnation point and radial direction were examined experimentally by the direct photos and data acquisitions from heat flux sensor. In this work, we could find the incurved flame behavior of line shaped inner top-flame in very closed distance between flat plate and burner exit, which has been not reported from general gas-fuels. There were 3 times of maximum and 2 times minimum heat flux of stagnation point with respect to the impinging distance for the investigation of Reynolds number and equivalence ratio effect. It was confirmed that the maximum heat flux of stagnation point in 1'st and 2'nd peaks increased with the increase of the Reynolds number due to the Nusselt number increment. There was a third maximum rise in the heat flux of stagnation point for larger separation distances and this phenomenon was different each for laminar and turbulent condition. The heat transfer characteristics between the stagnation and wall jet region in radial heat flux profiles was investigated by the averaged heat flux value. It has been observed that the values of averaged heat flux traced well with the characteristics of major parameters and the decreasing of averaged heat flux was coincided with the decreasing trend of adiabatic temperature in spite of the same flow condition, especially for impinging distance and equivalence ratio effects.

Fabrication of EEG Measuring System with High Precision Characteristics (고정밀도의 뇌파측정시스템 개발 연구)

  • 도영수;장호경;한병국
    • Progress in Medical Physics
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    • v.13 no.3
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    • pp.156-162
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    • 2002
  • In this study, we attempted in preparing high precision EEG measuring equipment. To measure EEG in high efficiency, pre-amplifier should get high performance common mode rejection ratio. Also, separation amplifier is essential to eliminate common line noise. So, our study were pointed at elevating the efficiency of eliminating noise, user safety and low noise characteristics. Prepared high precision pre-amplifier for EEG was A/D converted to automatically classify $\alpha$ wave, $\beta$ wave and $\theta$ wave. And converted data were Fast Fourier Transformed with real time DSP (Digital Signal Processing). Clinical demonstrations were carried out with healthy students, aged between 20 to 26 who has no histories of illness. To recognize the efficiency of the EEG, prepared EEG were used with MS equipment in low stimulated state and high stimulated state. Then, we studied at the effect of sensitivity on brain wave. From this study, it is known that our EEG equipment is efficient in sensitivity evaluation and suitable stimulations for each psychological state are required.

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A Study on the Joint and Splice of wooden Structure at Geunjeongjeon Hall of Gyeongbok Palace in the late Joseon Dynasty (조선후기 경복궁 근정전 주요 구조재의 맞춤과 이음에 관한 연구)

  • Jung, Yun-Sang
    • Journal of architectural history
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    • v.16 no.1
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    • pp.83-99
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    • 2007
  • This study examines the joint and splice of wooden structure at Geunjeongjeon Hall of Gyengbok Palace, which was constructed in the late Joseon Dynasty. The scope of the study is on the part of columns, the bracket sets, and the frame structure. This research also deals with the relationship between vortical load and horizontal load. Firstly, the examination of the joint and splice methods between the pillar and penetrating ties is on the joint and splice methods of the outer and corner. Through the investigation, it is verified that the joint methods between pillar and penetrating tie on the outer and corner pillars is the method of Sagal joints(cross joints, 사개맞춤). Joints used between pillar and penetrating tie are dovetailed tenon joints, between columns and Anchogong(안초공), between columns and Choikgong(초익공) are tenon joint(장부맞춤). Secondly, the examination of the joint and splice methods of the bracket set is on that of Salmi and Cheomcha(첨차), and Salmi and Janghyeo(장혀). Joints used between Salmi and Cheomcha, Salmi and Janghyeo are halved joint, and between each Janghyeo are stepped dovetailed splice. It is Cheomcha that is used the Jujang-Cheomcha(주장첨차) on center line. Therefore it is connected with each bracket set, which gets to is the strong system, easy and convenient on the construction of that. Thirdly, the frame structure of wooden architecture in royal palace is consist of purlins and beams, Janghyeo(장혀, timber under purlin), tall columns, king posts, etc. Through the investigation, it is verified that the joint and splice methods between purlins and beams are used with the methods of Sungeoteok joint(숭어턱맞춤). It is verified that the joint and splice methods between beams and high columns are used with methods of mortise and tenon joint(장부맞춤), is highly related with tensile force. To reduce the separation of parts, sangi(산지) and tishoi(띠쇠) are used as a counterproposal, which were generally used for architecture in royal Palaces in the late Joseon Dynasty and continued to be used until these days common wooden architecture.

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A Facility Design Model for 1300 Capacity School Foodservice with Adjacency and Bubble Diagrams (근접요구도와 버블다이어그램을 적용한 1300식 규모의 학교급식 시설 설계 모델)

  • Jang, Sun-hee;Chang, Hye-Ja
    • Korean Journal of Community Nutrition
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    • v.16 no.1
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    • pp.98-112
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    • 2011
  • This study aimed to suggest a 1300 scale of a middle school foodservice facility floor plan which was compliant to the principle of HACCP, as well as ensuring food and work safety, and the flow of personnel and food materials. which consisted of 46 nutrition teachers and 6 experts, responded with a questionnaire on the relationship of functional area and space. Using their opinions, key principles for the design of the facility were single direction movement of food materials, customers and workers; minimization of the cross-contamination through the separation of functional space; and securement of customer-focused efficiency; staff-centered convenience and efficiency; and work and food safety. After the completion of an adjacency diagram, bubble diagram and program statement, the functional areas of a 1300 scale middle school food-service facility were allocated as follows: $9.9\;m^2$ for the receiving area, $56.1\;m^2$ for the pre-preparation area, $10.5\;m^2$ for the food storage area, $6.0\;m^2$ for the supplies storage area, $97.8\;m^2$ for the cooking area, $33.6\;m^2$ for the service area, $52.5\;m^2$ for dish washing area, cafeteria $410.5\;m^2$, $4.5\;m^2$ for the front room, for a total of $725.8\;m^2$. Expert groups have pointed to limitations within this model as there are no windows in the office for the influx of fresh outside air and a need for the straight line installation of steam-jacket and frying kettles on the sides of windows. This study can be useful as the guidelines for estimating the investment cost of the facility and placing the placement of functional areas and equipment in the renovation of the facility. It can be also useful data for a methodology of foodservice facility design.

Analysis of Equivalent Circuit Approach for Ridge Type CPW Traveling - Wave Structure (릿지 형태 CPW 진행파형 구조의 등가회로 분석)

  • 윤상준;공순철;옥성해;윤영설;구민주;박상현;최영완
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.41 no.3
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    • pp.45-54
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    • 2004
  • Microwave characteristics of ridge type CPW traveling-wave(TW) electroabsorption modulator and photodetector are affected by the thickness of intrinsic layer, width of guiding layer, and the separation of signal and ground electrodes. These factors are determined effective index of microwave and characteristic impedance due to changing of capacitance(C) and inductance(L) of device. However, conventional equivalent circuit of TW-structure is approximated to microstrip and CPW transmission line by distribution of electric and magnetic fields, respectively. In this paper, we analyzed microwave characteristics of TW-structure and found more accurate value of C and L by using finite difference time domain (FDTD) method. These values are adopted circuit element of equivalent circuit. Microwave characteristics obtained by the FDTD and equivalent circuit model show good agreement.