• Title/Summary/Keyword: Seoul Park

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A Study on Changes and Meanings of Seoul Boramae Park as a Park Created in Relocated Sites (이전적지 공원으로서 서울 보라매공원의 변화와 의미)

  • Seo, Young-Ai;Park, Hee-Soung;Gil, Jihye;Kim, Jung-Hwa;Lee, Sang Min;Choi, Hyeyoung
    • Journal of the Korean Institute of Landscape Architecture
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    • v.51 no.1
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    • pp.85-97
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    • 2023

  • Seoul Boramae Park was opened on May 5, 1986, after the Republic of Korea Air Force Academy relocated to Cheongju City in 1985. This study aims to examine the birth and evolution of Seoul Boramae Park and diagnose the park's value being transformed from the former site of the Air Force Academy. Policy reports and newspaper data were analyzed as a research method, focusing on Seoul public records. The study results are as follows. First, Seoul Boramae Park is a large-scale park created before the policy for parks on relocated sites we enacted. Second, Seoul Boramae Park has historical value as an urban park where memories and traces of the Air Force Academy overlap. Third, Seou Boramae Park contributed to regional change by promoting the public value of parks created on the relocated sites with an urban planning method. Seoul Boramae Park has implications for Korean landscape history as a case of securing large green areas in Seoul and presenting its function and roles as a park created on a relocated site.

  • https://doi.org/10.9715/KILA.2023.51.1.085 인용 PDF

PARK2 Induces Osteoclastogenesis through Activation of the NF-κB Pathway

  • Hong, Seo Jin;Jung, Suhan;Jang, Ji Sun;Mo, Shenzheng;Kwon, Jun-Oh;Kim, Min Kyung;Kim, Hong-Hee
    • Molecules and Cells
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    • v.45 no.10
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    • pp.749-760
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    • 2022

  • Osteoclast generation from monocyte/macrophage lineage precursor cells needs to be tightly regulated to maintain bone homeostasis and is frequently over-activated in inflammatory conditions. PARK2, a protein associated with Parkinson's disease, plays an important role in mitophagy via its ubiquitin ligase function. In this study, we investigated whether PARK2 is involved in osteoclastogenesis. PARK2 expression was found to be increased during the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast differentiation. PARK2 gene silencing with siRNA significantly reduced osteoclastogenesis induced by RANKL, LPS (lipopolysaccharide), TNFα (tumor necrosis factor α), and IL-1β (interleukin-1β). On the other hand, overexpression of PARK2 promoted osteoclastogenesis. This regulation of osteoclastogenesis by PARK2 was mediated by IKK (inhibitory κB kinase) and NF-κB activation while MAPK (mitogen-activated protein kinases) activation was not involved. Additionally, administration of PARK2 siRNA significantly reduced osteoclastogenesis and bone loss in an in vivo model of inflammatory bone erosion. Taken together, this study establishes a novel role for PARK2 as a positive regulator in osteoclast differentiation and inflammatory bone destruction.

  • https://doi.org/10.14348/molcells.2022.0058 인용 PDF KSCI

Discovery of New Star Clusters in NGC 6822

  • Hwang Narae;Lee Myung Gyoon;Lee Jong Chul;Park Won-Kee;Park Hong Soo;Park Jang-Hyun;Sohn Sangmo Tony;Lee Sang-Gak;Lee Hyung Mok;Chun Mun-Suk;Lee Young-Wook;Sohn Young-Jong;Yuk In-Soo
    • The Bulletin of The Korean Astronomical Society
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    • v.29 no.2
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    • pp.26.1-26.1
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    • 2004

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