• Title/Summary/Keyword: Seo, Byung-Hyo

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Stability of Various Liposome Formulation Containing the Phytochemical-Peptide Derivatives (파이토케미컬 펩타이드 유도체를 포함하는 다양한 리포좀 제형의 안정성)

  • Han, Byung Seok;Kim, Su Young;Lee, Kyung Rok;Seo, Hyo Hyun;Moh, Sang Hyun
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.2
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    • pp.135-143
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    • 2016
  • In this study, we investigated the stability of the liposome formulation containing the phytochemicals-peptide derivatives. Among liposomes prepared using lecithins or surfactant under various conditions, the most stable niosome was obtained by using sodium palmitoyl sarcosinate and macadamia intergrifolia seed oil. The stability of peptide-containing niosome (N9) was confirmed by the TEM images. The N9 was stable at 0 and 45 degrees by Turbiscan, and its particle size was 95.7 nm. The N9 showed zeta potential value of -78.19 mV, and peptide-inclusion rate of 65.2% by BCA assay.

Analysis of Korean Patent Information for Air Extraction Cupping Devices

  • Lee, Tae Wook;Kim, Ku Weon;Kim, Hyo Jin;Choi, Ji Won;Choi, Seo Young;Lee, Byung Ryul;Yang, Gi Young
    • Journal of Acupuncture Research
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    • v.36 no.1
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    • pp.28-32
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    • 2019
  • Background: The purpose of this study was to collate inventors' improvements of air extraction cupping technology by reviewing patent applications in Korea. The cost of procurement and use of air extraction cupping devices are covered by health insurance. Methods: Patents registered in Korea for air extraction cupping devices from August 1992 to January 2018 (registration, expiration, rejection, abandonment, and disclosure) were analyzed to determine technology trends. The Korean patent search engine used was Kipris (www.kipris.or.kr). Results: Sixty-seven Korean patents for air extraction cupping devices were retrieved. Most patents focused on design of the top valve of the device, the device at the bottom, an internal device, and the disposable cupping glass. In total 17.9% of patents were registered and 64.2% were abolished [either from non-payment of registration fees (93%) or expiration of the patent after 10 years (7%)]. The average registration period was 3.7 years. Conclusion: The patents retrieved for this study focused on the development of the air exhaust valve, disposable cups, and skin adhesion maintenance technology in cupping devices that use air extraction. The average registration period was 3.7 years, meaning the patents that were not commercialized, expired without additional registration renewals. It is important to acquire a New Excellent Technology certificate for a cupping device to promote commercialization.

Electrochemical Characteristics of Si/SiO2/C Anode Material for Lithium-Ion Battery According to Addition of CNT and CNF Compounds (CNT와 CNF 복합첨가에 따른 Si/SiO2/C 음극활물질의 전기화학적 특성)

  • Seo, Jin-Seong;Yoon, Sang-Hyo;Na, Byung-Ki
    • Korean Chemical Engineering Research
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    • v.59 no.1
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    • pp.35-41
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    • 2021
  • Silicon is a promising next-generation anode material for lithium-ion battery, and it has been studied for commercialization due to the high theoretical capacity. However, it has problems of the volume change during charge-discharge and the poor electrical conductivity. To solve these problems, formation of SiO2 and carbon coating on the surface of silicon crystal were performed to protect the side reaction and enhance the electrical conductivity of silicon. CNT and CNF were also added to mitigate the volume change and increase the conductivity. Physical properties of asprepared samples were analyzed by XRD, SEM, and EDS. Electrochemical characteristics were investigated by electrical conductivity measurement, EIS, CV and cycle performance test. (Si/SiO2/C)+CNT&CNF showed high electrical conductivity and low charge-transfer resistance, and the capacity was 1528 mAh/g at 1st cycle and 1055 mAh/g at 50th cycle with 83% capacity retention.

Pressure Drop Analysis on Filling of Hydrogen Fuel Cell Vehicles (수소연료전지 차량 충전에서의 압력강하 분석)

  • Hyo Min Seo;Byung Heung Park
    • Journal of the Korean Institute of Gas
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    • v.27 no.1
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    • pp.38-47
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    • 2023
  • In the hydrogen filling process, hydrogen flows by the pressure difference between the supply pressure at a filling station and a storage tank in the vehicle, and the flow rate depends on the pressure difference. Therefore, it is essential to consider the pressure drop of hydrogen occurring during the filling process, and the efficiency of the hydrogen filling process can be improved through its analysis. In this study, the pressure drop was analyzed for a hose, a nozzle/receptacle coupling, a pipe, and a valve in a filling line. The pressure drops through hose and pipe, the nozzle,receptacle coupling, and the valve were calculated by using a equation for a straight conduit, a flow nozzle formula, and a gas flow respectively. In addition, as a result of comprehensive analysis of the pressure drop effect occurring in each component, it was found that the factor that has the greatest influence on the pressure drop in the entire filling line is the pressure drop through the valve. This study can be used to develop a model of the hydrogen filling process by analyzing hydrogen flow including hydrogen filling in the future.

A clinical Case Report of Spastic Patient After Stroke Treated with Gagamyounjo-tang (뇌경색 후유증으로 발생한 주관절 경직 환자의 가감윤조탕(加減潤燥湯) 치험1례)

  • Shim, Hyo-ju;Kim, Byung-chul;Woo, Sung-ho;Na, Eu-jin;Hwang, Jin-woo;Kang, Rae-yeop;Kim, Yong-ho;Seo, Ho-seok;Kim, Jin-won;Song, Su-chul
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.8 no.1
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    • pp.40-47
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    • 2007
  • Many patients have difficulties after stroke. Spasticity is an important one of that difficulties. So in these days, its management is becoming a major issue in rehabilitation. Gagamyounjo-tang was administered to a patient have had spasticity after stroke include Hyulhu(血虛) symptoms. And check the modified Ashworth Scale, Motor grade and VAS for being in the hospital. After treated with Gagamyounjo-tang, Modified Ashworth Scale, Motor grade and VAS have improved, and most of all symptoms about hyulhu(血虛) was disappeared. Based on this result, this study shows that Gagamyounjo-tang was effective in spasticity after stroke especially included Hyulhu(血虛) symptoms.

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Preparation and Characterization of Cy5.5-conjugated Biocompatible Polymeric Micellar Nanoparticles for Optical Imaging (광학 영상을 위한 Cy5.5가 결합된 생체적합성 고분자 마이셀 나노입자의 제조 및 특성분석)

  • Kim, Hyo-Jeong;Kim, Byung-Jin;Lee, Ha-Yeong;Jung, Suk Hyun;Jeong, Seo-Young;Yuk, Soon-Hong;Shin, Byung-Cheo;Seong, Ha-Soo;Choi, Youn-Woong;Ha, Dae-Chul;Choi, Sun-Hang;Lee, Soo-Min
    • Journal of Pharmaceutical Investigation
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    • v.39 no.6
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    • pp.393-400
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    • 2009
  • PHEA (hydroxyethyl-aspartamide)-mPEG (methoy-polyethyleneglycol)-$C_{16}$ (hexadecylamine)-ED (ethylenediamine) was prepared as a drug delivery carrier. The structure and molecular weight of polymers were characterized by $^1H$-NMR and gel permeation chromatography. Micelle size and shape were measured by electro-photometer light scattering and transmission electron microscope. The mean diameter of micelles was 23 nm in aqueous solution. To evaluate the potential of these polymeric micelles as a drug carrier, PSI-mPEG-$C_{16}$-ED was conjugated with Cy5.5 for Near-Infrared Fluorescent (NIRF) based optical imaging. PSI-mPEG-$C_{16}$-ED-Cy5.5 was injected intravenously into mice (n=5) and in vivo NIRF imaging was performed during 48 h after injection. The biodistribution study at 24 h after injection showed the longcirculation property of PSI-mPEG-$C_{16}$-ED-Cy5.5. Therefore, PSI-mPEG-$C_{16}$-ED micelles could be a promising drug carrier and imaging agent.

Glasswort Powder Diet Activates Lipid Metabolism in Rat (함초분 첨가 고지방식이 흰쥐의 지방대사 연구)

  • Seo, Hyo-Bin;Kwak, Yun-Young;Nam, Ju-Ock;Song, Young-Ju;Kim, Byung-Oh;Ryu, Sung-Pil
    • Journal of Life Science
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    • v.22 no.4
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    • pp.478-485
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    • 2012
  • The purpose of this study was to investigate the effects of glasswort powder intake on lipid metabolism. Rats were divided into three groups: a group fed a normal diet (CON), one fed a high fat diet (HFC), and one fed a high fat diet with glasswort powder (HFG). They were fed their respective diet for four weeks. Body weight was significantly lower (9%) in the HFG group than in the HFC group at the fourth week. According to the feces analysis, the HFG group showed the highest fat level (120% vs. CON; 138% vs. HFC) and fecal calories (110%). The concentration level of TG and LDL-C was 71.8% lower in the HFG group compared to the HFC group, while the concentration level of HDL-C was 152% higher in the HFG group. Expression of FABP in the liver was 197% greater in the HFG compared to the HFC group, with the expression of CPT-1 showing a similar tendency. These results suggest that glasswort powder intake suppresses weight gain and improves fat metabolism at the level of liver cells. From these results, we suggest that glasswort powder is effective against obesity by inhibiting the absorption of fat in the digestive tract.

Study on Landslide Flume Tests Using Stability Analysis of the Unsaturated Infinite Slope (불포화 무한사면의 안정해석을 활용한 산사태 모형실험에 관한 연구)

  • Song, Hyo-Sung;Chae, Byung-Gon;Song, Young-Suk;Choi, Jung-Hae;Seo, Won-Gyo;Woo, Ik
    • The Journal of Engineering Geology
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    • v.29 no.4
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    • pp.541-552
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    • 2019
  • In this study, landslide flume tests were performed to analyze characteristics of ground characteristics and landslide occurrence due to rainfall infiltration. As test materials, weathered granite soil and gneiss soil, the most frequent landslides in Korea, were used, and landslides were triggered by heavy rain (Intensity = 200 mm/hr). The measurement sensors were installed with 3 sets at toe, slope, top part and shallow (GL-0.2 m), middle (GL-0.4 m), and deep (GL-0.6 m) depth in the slope and measured at 10 second intervals. After landslide flume tests, the slope stability analysis was performed by applying the unsaturated soil theory based on the change of ground characteristics and compared with actual landslide occurrence from flume test. As a result of the analysis, factor of safety reflected the landslide occurrence from flume test and factor of safety decreased as rainfall infiltration, leading to slope failure. Finally we compared to the factor of safety below 1 and actual landslide occurrence time, the average difference was 1,600 seconds for weathered granite soil and 5,400 seconds for weathered gneiss soil.

Photostimulated Luminescence and Photoluminescence of SrCl2:Eu2+ Phosphors (SrCl2:Eu2+ 형광체의 광발광 및 광자극발광 특성)

  • Doh, Sih-Hong;Seo, Hyo-Jin;Kim, Young-Kook;Kim, Do-Sung;Kim, Sung-Hwan;Kim, Chan-Jung;Lee, Byung-Hwa;Kim, Wan;Kang, Hee-Dong
    • Journal of Sensor Science and Technology
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    • v.11 no.6
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    • pp.319-326
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    • 2002
  • $SrCl_2:Eu^{2+}$ phosphors were prepared by the solid phase reaction method, and their photostimulated luminescence(PSL) and photoluminescence(PL) characteristics were investigated. The PSL and PL peak of the $SrCl_2:Eu^{2+}$ phosphors are due to the $5d{\rightarrow}4f$ transition of $Eu^{2+}$ ions in phosphors. The PSL and PL spectrum obtained by the 355nm excitation was observed in $380{\sim}440\;nm$ region with the peak at 407 nm. The dose response of the PSL phosphors were linear within $2.5\;mGy{\sim}200\;mGy$ of 100 kV X-ray. The fading of the phosphors at room temperature was approximately 60% after 20 min.

Case Report of Hemiplegia after apoplexy in a Patient with Monoplegia on Right upper Extremity Treated with Herbal Prescription (우상지(右上肢) 단마비(單痲痺)가 주증(主症)인 풍비 환자의 만금탕가미방(萬金湯加味方) 투여 호전 1례)

  • Jeong, Byeong-Ju;Woo, Sung-Ho;Kim, Byung-Chul;Kim, Yong-Ho;Seo, Ho-Seok;Hwang, Gyu-Dong;Jang, Ha-Jeong;Nam, Hyo-Ick;Kim, Hoi-Young;Kim, Jin-Won
    • The Journal of Internal Korean Medicine
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    • v.27 no.1
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    • pp.288-293
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    • 2006
  • Background : Monoplegia is the paralysis of a limb. It is commonly caused by an injury to the cerebral cortex, and rarely caused by injury to the internal capsule, brain stem, or spinal cord. Most problems with cerebral cortex is derived from the occlusion of a brain cortex blood vessel due to thrombus or embolus. Objectives : This study is to see if there is a significance in thermal differences of acupoints in diagnosis and treatment of monoplegia on an upper extremity to test the validity of acupuncture and herbal treatment for it. Methods : By using Digital Infrared Thermographic Imaging(DITI), thermal differences$({\Delta}T)$ of acupoints on the upper extremity in a patient with monoplegia on the right upper extremity were measured after an attack of the disease. By giving Mangeum-tang(萬金湯) and treating the patient with acupuncture. the temperature changes of the upper extremity were examined through DITI and improvement was observed. Results : Compared with the left arm which suffered no such injury, the right recovered about 80% of sensation, and the grade of monoplegia improved from Grade O to Grade V. Also, the temperatures of right palmar-dorsal hand and the region of Weiguan(外關, Waiguan, TE5) were $1^{\circ}C$ and $1.45^{\circ}C$ higher than the same left region on admission day, but the thermal differences$({\Delta}T)$ narrowed to $0.5^{\circ}C$ by the last day. Conclusions : Results suggest that DITI screening is a reliable method of prognosis and that the time required for treatment can be estimated through this method in cases of monoplegia to an upper extremity. Also, progress in treatment is reflected in thermal differences of acupoints of the monoplegic upper extremity in accordance with the theory of meridian. This supports a role for acupuncture and herbal treatment for monoplegia.

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