Canine skin is a highly dynamic organ that is constantly adapted to changes in its environment. It provides structural, sensory, immunologic, and physiologic functions and contributes an essential barrier function against potential environmental insults. We assessed the changes of canine skin hydration, pH, and protein contents by noninvasive method according to the frequency of application with canine commercial shampoo. Canine commercial shampoo was applied topically every other day, 5 days, and 8 days on different sites, respectively in 8 dogs. Saline-applied site was as a control. Skin hydration was increased and skin surface pH was decreased significantly in canine commercial shampoo-applied site every other day (p < 0.05). Also, skin protein concentration measured by D-squame$^{(R)}$ tape stripping method was increased significantly in canine commercial shampoo-applied site every other day (p < 0.05). There were alterations on every 5 days and 8 days, but not significantly. These results may be recognized that the frequent use of canine commercial shampoo cause abnormalities of the skin barrier function and alteration of stratum corneum integrity/cohesion. Consequently it was suggested that bathing the dog with canine commercial shampoo was appropriate every 5 or 8 days.
The enhancement of inquiry skills has been emphasized as a important objective of science education for a long time. Of these, the observation is not only a simple and basic skill, but also a very important skill, in aspect of gathering informations about the nature of all things around us, through interaction between the sense organs of body and objectives. The purpose of this study is to investigate the results of observations about the grasshopper(Oxya chinesis), made by the elementary student from the 3rd to the 6th grade, and to make use of them as the basic materials for the observative teaming and the evaluation of the observation ability. Through this study, the collected items of observation are as follows For grasshopper, a total of observation items is 95, 70 using the sight sense, 13 using the tactile sense,7 using the olfactory sense. 3 using the palate sense and 2 using the auditory sense. In this study, the findings of elementary student's observation are as follows. 1. On the whole, most of students have observed mainly by the sight and the tactile sense, when observing the grasshopper. 2. It is showed a tendency that the observation ability of student is increased with the higher grade in elementary school. 3. As the grade ascends. the observations with operating are increased, also the quantitative expression and interpretation about them are increased. 4. In the case of same grade, there is no significant difference between students' gender, though girls' ability of the observation showed somewhat higher than boys' 5. Occasionally, the interpretations on the observative facts made by student, are inaccurate. Basis on the above results, we suggested some directions for the improvement of the observative learning program in science classroom of elementary school. First, the teacher have to serve as a guide and encouragement in the observative learning class, to be accomplished the various observation, which all the sensory organ can be used by student than the sight sense. Second, to get elevated the ability of observation, it is necessary that some experimental tools(magnifying lens, stereoscope, auxiliary implements etc.) are utilized. Third, the teacher have to make often endeavors showing an example of operation, to be activated the atmosphere of operative observation.
The inner ear is a complex sensory organ responsible for hearing and balance. Formation of the inner ear is dependent on tight regulation of spatial and temporal expression of genes that direct a series of developmental processes. Recently, epigenetic regulation has emerged as a crucial regulator of the development of various organs. However, what roles higher-order chromatin organization and its regulator molecules play in inner ear development are unclear. CCCTC-binding factor (CTCF) is a highly conserved 11-zinc finger protein that regulates the three-dimensional architecture of chromatin, and is involved in various gene regulation processes. To delineate the role of CTCF in inner ear development, the present study investigated inner ear-specific Ctcf knockout mouse embryos (Pax2-Cre; $Ctcf^{fl/fl}$). The loss of Ctcf resulted in multiple defects of inner ear development and severely compromised otic neurogenesis, which was partly due to a loss of Neurog1 expression. Furthermore, reduced Neurog1 gene expression by CTCF knockdown was found to be associated with changes in histone modification at the gene's promoter, as well as its upstream enhancer. The results of the present study demonstrate that CTCF plays an essential role in otic neurogenesis by modulating histone modification in the Neurog1 locus.
Journal of The Korean Society of Integrative Medicine
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v.9
no.1
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pp.33-40
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2021
Purpose : The fascia is the body's largest sensory organ affected by mechanical stimuli such as pressure. Fascial distortion model (FDM) is one of the fascia treatment techniques, and it is based that most musculoskeletal problems are caused by three-dimensional distortion of the fascia. Until now, some studies have been conducted to investigate the effect of FDM, but it is still not enough. In this study, among the six techniques of FDM, trigger band (TB) and cylinder distortion (CyD) were applied to the forearm to investigate the immediate effect on the maximal grip strength, force sense and range of motion. Methods : 22 healthy adults in their 20s and 30s participated. Before and after the application of FDM, maximal grip strength, force sense and range of motion were measured. For analysis, a paired t-test was performed, and the significance level was set to p<.05. Results : After FDM, there were a significant differences that increased the force sense and the range of motion (p<.05). But the maximal grip strength did not show a significant difference (p>.05). Conclusion : The results of this study, the FDM did not affect maximal grip strength, but it was shown to increase the sense of force and range of motion. We assumed that it is the result of the changes in the states of the fascia and changes in the activity of mechanical receptors induced by pressure and stretch from FDM application.
Kim, Ye Youl;Park, Sun Young;Kang, Sang-In;Yoon, In-Seong;Hwang, Ji-Young;Kim, Jin-Soo
Korean Journal of Fisheries and Aquatic Sciences
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v.55
no.3
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pp.239-248
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2022
This study was conducted to compare sensory and nutritional and digestive properties of the Israeli carp Cyprinus carpio muscle (ICM) by size [normal large (NLF) and small (NSF) fish], part [ventral (VM) and dorsal (DM) muscle], and commercial value [NLF, recessive (RF) or deformed (DF) fish]. In NLF, the major amino acids were lysine, aspartic acid, and glutamic acid, whereas aspartic acid and glutamic acid were predominant in NSF, DM, VM, DF, and RF. Taurine content increased with fish size, and was higher in DM than in VM, and higher in NLF than in DF but lower than that in RF. Regardless of ICM size, part, and commercial value, potassium and iron were expected in the health function, but calcium and zinc were not expected. The major fatty acids present in ICM were 16:0, 18:1n-9, and 18:2n-6, regardless of size, part, and commercial value. The digestion rate of ICM by digestive organ was lower in NLF than in NSF, and lower in VM with a high lipid content than in DM, and lower in DF than in RF.
Journal of the Korean Society of Systems Engineering
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v.20
no.spc1
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pp.56-64
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2024
This study aims to compare and evaluate the usability of domestic and overseas XR devices. With the recent release of 'Apple Vision Pro', interest in the XR field is increasing rapidly. XR devices are being used in various fields such as defense, medical care, education, and entertainment, but the evaluation system for evaluating usability is still insufficient. Therefore, this study aims to derive improvements in domestic equipment through comparative evaluation of usability for two HMD-type devices and one glasses-type device that are released. In order to conduct the study, 20 participants in their 20s to 30s who were interested in XR devices and had no visual sensory organ-related disabilities were evaluated by wearing VR equipment. As a quantitative evaluation, electromyography through an EMG sensor and the device and body temperature of the device through a thermal imaging camera were measured. As a qualitative evaluation, the safety of wearing, ease of wearing, comfort of wearing, and satisfaction of wearing were evaluated. As a result of comparing the usability of the devices based on the results, it was confirmed that domestic HMD-type device needs improvement in the strap part.
The purpose of this study is to analyze forest healing from a Buddhist perspective and improve its effect, and the forest has a close relationship with Buddhism than any religion. the Buddha's life is connected to forest and tree, which is caused by the spiritual nature and role of forest. Healing deals with the problem of suffering of the mind, and in Buddhism, it is solved through practice. By understanding the phenomenon of delusions such as thoughts, greed, and bad feelings about sensory control, vhfptmxmhelps to escape from the desire to pursue unnecessary stimuli or external objects, Human beings can get comfort and pleasure through the five senses in the beautiful natural scenery, and find the stability of the mind. This is because when entering the forest, good environments that prevent the 6th consciousness from growing delusions way the operation of the five senses are contained in the forest, This study is a preliminary study that analyzed the effects based on the natural environmental healing factor and Buddhist theory of forests based on previous studies, As a result of examining whether Buddhism can maximize the healing effect of forest healing, it was confirmed that it can contribute to activation along with existing forest healing techniques, The verification of the effectiveness will be left as a follow-up research project through future experimental research, and this study is expected to contribute to the activation of forest healing effect.
Lee Young Su;Kwack Jeong Jin;Lee Gang Nyoung;Choi Chang Won;Kim Hee Chul
Journal of Physiology & Pathology in Korean Medicine
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v.16
no.4
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pp.630-636
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2002
After The Yellow Emperor's Canon of Internal Medicine, The text researches of pathologic change to the liver disease concluded the next, 1, The category of liver-disease(肝病) include the Symptoms of abnormality due to vital energy and blood motion, emotion and intention, muscular and reproductive function, and legions around descending liver channel. 2. In the theory that Liver-Yang energy(肝陽氣) is always overproducing, Liver-Yin blood(肝陰血) is always lacking, pathologic characteristics for liver disease is functional change of malfunction of the use of body(體用失調), So nourishing the liver and kidney is used for the principal aspects of a disease. regulating and calm the liver is used for the secondary aspects of a disease as the treatment plan, 3. If malfunctioning of the functions of dispersion and discharge(疏泄), Iiver-energy(肝氣) is becoming degected, So overproduct and overflow of ascent and exhalation of liver-yang(肝陽) is becoming blood are ascending following energy. complete usage of Yin-blood(陰血) is responsible for some kinds of mass formed by blood stasis in the early stage of pathogenesis of liver disease syndrome of the energy system as the progession of disease extravasated blood is forming. the pathologic characteristics is appeared loss of control of the vital energy and blood(體用失調) at the liver disease. 4. Sthenia-syndrome of liver(肝實證) and liver-heat syndrome(肝熱證) is appered that overproducing and overflow of dispersion(疏泄太過) and discharge is responsible for overfunctioning of liver disease or some kinds of heat syndrome such as liver fire(肝火), Sthenia of liver-yang(肝陽上亢), the syndromes of sthenic liver heat(肝實熱) are appered. deficiency of the liver(肝虛證) and cold syndrome of liver(肝寒證) is classified pathologic characteristics of cold and heat, deficiency and excess that regression of sensory, motor, mental due to lack of dispersion and discharge(疏泄不及), or intruding of the cold miasma, are degected. 5. The liver is close relation of physiologic function and internal organ such as spleen, stomach, lung, heart, kidney, gall bladder by the meridian channels, because of property of wind Zang, rapid progession is classified by phthologic charateristics.
For satisfying consumer needs, commercial facilities require a variety of sale-related space expressions and eye-catching product arrangements; space composition can also be a direct marketing strategy. The human eye is the sensory organ that acquires the largest amount of information, and an analysis of visual information helps in understanding visual relations between . However, the existing studies are mostly focused on analysis of still frames in experimental images, and there is a lack of studies analyzing gaze information based on mobile images of commercial spaces. Therefore, this study analyzed emotional responses through gaze information of space users in reality using a video of a movement route through a commercial facility. The analysis targeted straight sections of the moving route; based on the data acquired, sectional characteristics of five gaze intensity ranges were examined. As a result, section A, the starting point of the route, had a low gaze intensity, while section B had the highest gaze intensity. This indicates that, starting in section B, the subjects explored the space in a stable way and needed time to adapt to the experimental video. In relation to space characteristics of the gaze-concentrated area, display formats of the right stores in 4 of 6 sections received greater attention. The gaze of consumers was mostly focused on props, and big gaze information was revealed in showcase display formats of the stores. In conclusion, this analysis method can provide highly useful direct design data about merchandise display and merchandise component arrangement based on consumer visual preference.
Kang, Nae Gyu;Kwak, Taek Jong;Kim, Jung A;Kim, Tae Hoon;Moon, Tae Kee;Park, Sun Gyoo;Song, Da Young;Lee, Su Jin;Chang, Min Youl;Jang, Hee Jung;Choo, Jung Ha;Jeong, Su Na
Journal of the Society of Cosmetic Scientists of Korea
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v.40
no.4
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pp.373-382
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2014
The skin is an organ that covers the outside of the human body. And it regulates body temperature, performs sensory function, deliveries the drug, and represents the abnormality of the internal organs. For these reasons, people have been expressing the condition of the body based on the state of the skin of the face to detect sign of health, "you look well", "face with vitality". Depending on the degree of aging and the environment, it is a fact that skin color, skin texture, moisture and firmness could be different. In particular, the color of the skin acts as a factor that affects to determine the subjective impression such as beauty and charm. We could expect consumer's demand through the market of whitening cosmetics and skin treatment. However, existing most of the cosmetics focus on improving whiteness. The number of studies that focused on skin color is not enough. In this study, we found out the skin color condition by carrying out surveys of 100 women between 30s and 40s. Our study would be very useful to develop new cosmetic products and to satisfy customer's needs.
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