• Journal of Sensor Science and Technology
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• v.5 no.5
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• pp.21-29
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• 1996

A piezoresistive silicon acceleration sensor with 8 beams, utilized by an unique silicon micromachining technique using porous silicon etching method which was fabricated on the selectively diffused (111)-oriented $n/n^{+}/n$ silicon subtrates. The width, length, and thickness of the beam was $100\;{\mu}m$, $500\;{\mu}m$, and $7\;{\mu}m$, respectively, and the diameter of the mass paddle (the region suspended by the eight beams) was 1.4 mm. The seismic mass on the mass paddle was formed about 2 mg so as to measure accelerations of the range of 50g for automotive applications. For the formation of the mass, the solder mass was loaded on the mass paddle by dispensing Pb/Sn/Ag solder paste. After the solder paste is deposited, Heat treatment was carried out on the 3-zone reflow equipment. The decay time of the output signal to impulse excitation of the fabricated sensor was observed for approximately 30 ms. The sensitivity measured through summing circuit was 2.9 mV/g and the nonlinearity of the sensor was less than 2% of the full scale output. The output deviation of each bridge was ${\pm}4%$. The cross-axis sensitivity was within 4% and the resonant frequency was found to be 2.15 KHz from the FEM simulation results.

• Molecules and Cells
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• v.42 no.3
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• pp.270-283
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• 2019

This study was aimed to explore if lncRNA MALAT1 would modify chemo-resistance of non-small cell lung cancer (NSCLC) cells by regulating miR-197-3p and p120 catenin (p120-ctn). Within this investigation, we totally recruited 326 lung cancer patients, and purchased 4 NSCLC cell lines of A549, H1299, SPC-A-1 and H460. Moreover, cisplatin, adriamycin, gefitinib and paclitaxel were arranged as chemotherapies, and half maximal inhibitory concentration (IC50) values were calculated to evaluate the chemo-resistance of the cells. Furthermore, mice models of NSCLC were also established to assess the impacts of MALAT1, miR-197-3p and p120-ctn on tumor growth. Our results indicated that MALAT1 and miR-197-3p were both over-expressed within NSCLC tissues and cells, when compared with normal tissues and cells (P < 0.05). The A549, H460, SPC-A-1 and SPC-A-1 displayed maximum resistances to cisplatin ($IC50=15.70{\mu}g/ml$), adriamycin ($IC50=5.58{\mu}g/ml$), gefitinib ($96.82{\mu}mol/L$) and paclitaxel (141.97 nmol/L). Over-expression of MALAT1 and miR-197-3p, or under-expression of p120-ctn were associated with promoted viability and growth of the cancer cells (P < 0.05), and they could significantly strengthen the chemo-resistance of cancer cells (P < 0.05). MALAT1 Wt or p120-ctn Wt co-transfected with miR-197-3p mimic was observed with significantly reduced luciferase activity within NSCLC cells (P < 0.05). Finally, the NSCLC mice models were observed with larger tumor size and weight under circumstances of over-expressed MALAT1 and miR-197-3p, or under-expressed p120-ctn (P < 0.05). In conclusion, MALAT1 could alter chemo-resistance of NSCLC cells by targeting miR-197-3p and regulating p120-ctn expression, which might assist in improvement of chemo-therapies for NSCLC.

• Journal of Korean Neurosurgical Society
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• v.65 no.1
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• pp.96-106
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• 2022

Objective : The most common complication of anterior cervical discectomy and fusion (ACDF) is cage subsidence and maintenance of disc height affects postoperative clinical outcomes. We considered cage subsidence as an inappropriate indicator for evaluating preservation of disc height. Thus, this study aimed to consider patients with complications such as reduced total disc height compared to that before surgery and evaluate the relevance of several factors before ACDF. Methods : We retrospectively reviewed the medical records of 40 patients who underwent stand-alone single-level ACDF using a polyetheretherketone (PEEK) cage at our institution between January 2012 and December 2018. Our study population comprised 19 male and 21 female patients aged 24-70 years. The minimum follow-up period was 1 year. Twenty-seven patients had preoperative bone mineral density (BMD) data on dual-energy X-ray absorptiometry. Clinical parameters included sex, age, body mass index, smoking history, and prior medical history. Radiologic parameters included the C2-7 cobb angle, segmental angle, sagittal vertical axis, disc height, and total intervertebral height (TIH) at the preoperative and postoperative periods. Cage decrement was defined as the reduction in TIH at the 6-month follow-up compared to preoperative TIH. To evaluate the bone quality, Hounsfield unit (HU) value was calculated in the axial and sagittal images of conventional computed tomography. Results : Lumbar BMD values and cervical HU values were significantly correlated (r=0.733, p<0.001). We divided the patients into two groups based on cage decrement, and 47.5% of the total patients were regarded as cage decrement. There were statistically significant differences in the parameters of measuring the HU value of the vertebra and intraoperative distraction between the two groups. Using these identified factors, we performed a receiver operating characteristic (ROC) curve analysis. Based on the ROC curve, the cut-off point was 530 at the HU value of the upper cortical and cancellous vertebrae (p=0.014; area under the curve [AUC], 0.727; sensitivity, 94.7%; specificity, 42.9%) and 22.41 at intraoperative distraction (p=0.017; AUC, 0.722; sensitivity, 85.7%; specificity, 57.9%). Using this value, we converted these parameters into a bifurcated variable and assessed the multinomial regression analysis to evaluate the risk factors for cage decrement in ACDF. Intraoperative distraction and HU value of the upper vertebral body were independent factors of postoperative subsidence. Conclusion : Insufficient intraoperative distraction and low HU value showed a strong relationship with postoperative intervertebral height reduction following single stand-alone PEEK cage ACDF.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.37 no.4
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• pp.367-375
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• 2013

In this study, the characteristics of the heat transfer coefficient and pressure drop were numerically analyzed according to the axis ratio (AR), pitch, location of vortex generator, and bump phase of the tube surface about an elliptical fin-tube heat exchanger. The boundary condition for CFD analysis was decided as a tube surface temperature of 348 K and inlet air velocity of 1-5 m/s. RSM 7th turbulent model was chosen as the numerical analysis for the sensitivity level. The analysis results indicated that the AR and transverse pitch decreased whereas the heat transfer coefficient increased. On the other hand, there was little difference in the longitudinal pitch. Furthermore, the heat transfer rate was more favorable when the vortex generator was located in front of the tube. Also, the bump phase of the tube surface indicated that the pressure drop and heat transfer were more favorable with the circle type than with the serrated type.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.44 no.4
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• pp.423-430
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• 2011

The most satisfactory split-beam transducer for fish sizing maintains a wide bearing angle region for correct fish tracking without interference from side lobes and lower sensitivity to fish echoes outside of the main lobe region to correctly measure the angular location of free-swimming fishes in the sound beam. To evaluate the performance of an experimentally developed 50 kHz split-beam transducer, the angular location of a target was derived from the electrical phase difference between the resultant signals for the pair of transducer quadrants in the horizontal and vertical planes consisting of 32 transducer elements. The electrical phase difference was calculated by cross-spectral density analysis for the signals from the pair of receiving transducer quadrants, and the directivity correction factor for a developed split-beam transducer was estimated as the fourth-order polynomial of the off-axis beam angle for the angular location of the target. The experimental results demonstrate that the distance between the acoustic centers for the pair of receiving transducer quadrants can be controlled to less than one wavelength by optimization with amplitude-weighting transformers, and a smaller center spacing provides a range of greater angular location for tracking of a fish target. In particular, a side lobe level of -25.2 dB and an intercenter spacing of $0.96\lambda$($\lambda$= wavelength) obtained in this study suggest that the angular location of fish targets distributing within a range of approximately ${\pm}28^{\circ}$ without interference from side lobes can be measured.

• Journal of Biosystems Engineering
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• v.37 no.3
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• pp.192-200
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• 2012

Purpose: Aerial application of chemicals with an agricultural helicopter allows for precise and timely spraying and reduces working labor and pollution. An attitude controller for an agricultural helicopter would be helpful to aerial application operator. The objectives of this paper are to determine the transfer function models and to estimate the handling qualities of a bare-airframe model helicopter. Methods: Transfer functions of a model unmanned helicopter were estimated by using NAVFIT and DERIVID modules of the $CIFER^{(R)}$ program to the time history data of frequency sweep flight tests. Control inputs of the transfer functions were elevator, aileron, rudder and collective pitch stick positions and the outputs were resulting on-axis movements of the fuselage. Results: Minimum realization of the transfer functions for pitch rate output to elevator control input and roll rate output to aileron control input produced second order transfer functions with undamped natural frequencies around 3.0 Hz and damping ratios of 0.139 and 0.530, respectively. The equivalent time delays of the transfer functions ranged from 0.16 to 0.44 second. Sensitivity analysis of the proposed parameters allowed derivation of minimal realization of the transfer functions. Conclusions: Handling quality of the model helicopter was addressed based on the eigenvalues of the transfer functions, corresponding undamped natural frequencies with damping ratios. The equivalent time delays of the lateral-directional motion ranged from 0.16 to 0.44 second, longer than the 0.1 to 0.15 second requirement for well-controlled typical manned aerial vehicles.

• The Research Journal of the Costume Culture
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• v.16 no.1
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• pp.88-99
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• 2008

This study aims to analyze product samples of convergence of fashion and technology, as convergence is a major trend in the age of digital paradigm, and to propose desirable directions of development for technology convergence in fashion design in the future. With bibliographic research as well as internet search of the cases of development and commercialization of convergence of fashion and technology from the 1960s, when wearable computers were first introduced as an early development form of convergence, to the present, it becomes possible to classify these cases into three groups: functionally oriented one, aesthetically oriented one, and one that combines function and aesthetics. The pros and cons of each group of these cases are discussed and an evolutionary trend is observed from the earlier stage of convergence with functionally oriented cases which tried to achieve specific purposes of the time to the later stage of convergence with emphasis on both function and aesthetics which reflects the sensitivity of the general wearers. When three groups are plotted in the positioning map with one axis of function-aesthetics and the other of industry-fashion designer, however, all three are located outside of the two axes, suggesting these elements are not very well combined. In order for the products of the fashion-technology convergence in the future to receive favorable response from the consumers, it is necessary for the fashion industry to develop a close collaboration with companies of digital technology and the convergence products not only will have to provide functional benefits of the new technology but also to satisfy the aesthetic demands of the wearers.

• Structural Engineering and Mechanics
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• v.20 no.5
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• pp.543-558
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• 2005

The natural frequencies of a long span bridge vary during its construction and it is thus difficult to apply traditional tuned liquid column dampers (TLCD) with a fixed configuration to reduce bridge vibration. The restriction of TLCD imposed by frequency tuning requirement also make it difficult to be applied to structure with either very low or high natural frequency. A semi-active tuned liquid column damper (SATLCD), whose natural frequency can be altered by active control of liquid column pressure, is studied in this paper. The principle of SATLCD with adaptive tuning capacity is first introduced. The analytical models are then developed for lateral vibration of a structure with SATLCD and torsional vibration of a structure with SATLCD, respectively, under either harmonic or white noise excitation. The non-linear damping property of SATLCD is linearized by an equivalent linearization technique. Extensive parametric studies are finally carried out in the frequency domain to find the beneficial parameters by which the maximum vibration reduction can be achieved. The key parameters investigated include the distance from the centre line of SATLCD to the rotational axis of a structure, the ratio of horizontal length to the total length of liquid column, head loss coefficient, and frequency offset ratio. The investigations demonstrate that SATLCD can provide a greater flexibility for its application in practice and achieve a high degree of vibration reduction. The sensitivity of SATLCD to the frequency offset between the damper and structure can be improved by adapting its frequency precisely to the measured structural frequency.

• The Journal of the Acoustical Society of Korea
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• v.16 no.6
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• pp.61-67
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• 1997

Piezoelectric gyroscopes are the devices to measure angular rotational velocity of a system with respect to an inertial frame of reference means of the Coriolis principle. Most of current piezoelectric gyroscopes detect rotational velocity about a single axis of rotation. This paper describes development of a new dual axial gyroscope made out of the piezoelectric ceramic, PZT, which can overcome the limitation of the current single axial type. The validity of the new structure is checked through finite element analysis. Based on the design, an experimental sample of the sensor is fabricated and its performance is discussed in comparison with the theoretical expectation. The resutls show that the present gyroscope is capable of measuring the rotational velocity over two orthogonal axes simultaneously with good enough sensitivity and distinction between the two axial components of the rotation.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.8
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• pp.232-237
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• 2013

A newly developed fall detection algorithm using the HMM (Hidden Markov Model) extracted from the video is introduced. To distinguish between the fall from personal difference fall pattern or the normal activities of daily living (ADL), HMM machine learning algorithm is used. For getting fall feature vector of video, the motion vector from the optical flow is applied to the PCA (Principal Component Analysis). The combination of the angle, ratio of long-short axis, velocity from results of PCA make the new fall feature parameters. These parameters were applied to the HMM and the results were compared and analyzed. Among the newly proposed various kinds of fall parameters, the angle of movement showed the best results. The results show that this parameter can distinguish various types of fall from ADLs with 91.5% sensitivity and 88.01% specificity.