• Proceedings of the Technology Innovation Conference
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• 1996.12a
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• pp.27-62
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• 1996

As an exploratory attempt, this study examines the patterns of global R&D activities of industrial firms, focusing on the management of overseas R&D centers in terms of their location, primary missions, management style, organizational structure and communication and global human resource management system Based on a review of existing studies mainly undertaken in advanced countries and cases of foreign MNCs, several hypothetical relationships are postulated : 1) There appears a strong relationship between the purpose and location of R&D activities : 2) Different levels of global management and technological capability lead to different types of overseas R&D organizations : 3) The relationship between autonomy of overseas R&D organizations and their R&D performance will be moderated by organization size, development time pressure, and a need for internal efficiency : 4) Frequent communication between the headquarter and overseas R&D organizations will increase R&D performance 5) Mutual exchange of R&D professionals between the headquarter and overseas R&D organizations will be positively related with R&B performance. In addiction, this study explores the current state of global R&D activities of selective firms in Korea, based on ie-depth interviews, and analyzes the sources of problems in their global R&D management. Finally, theoretical and managerial implications of this study are discussed and future research directions are proposed.

• Journal of Korean Library and Information Science Society
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• v.39 no.3
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• pp.161-186
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• 2008

Through the present training condition of Korean teacher librarians and their supply-demand prospects, this paper pointed out problems both of the educational system and of its supply-demand and suggested the solution as well. Particularly, focusing on the educational system of teacher librarians and the present condition of the training organizations, this paper predicted their supply ability in the future and analyzed the demand which is necessary, when applying the standards of Korean Library Association and School Library Promotional Law with the selective situation of teacher librarians. In this way, the problems of supply-demand imbalance were indicated and, as a method for training the proper number which is required for the future demand, the rearrangement of the approval number of a course of study for the teaching profession and the establishment of Library and Information education department in education college were proposed.

• Molecules and Cells
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• v.40 no.9
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• pp.607-612
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• 2017

When mammalian cells and animals face a variety of internal or external stresses, they need to make homeostatic changes so as to cope with various stresses. To this end, mammalian cells are equipped with two critical stress responses, autophagy and cellular senescence. Autophagy and cellular senescence share a number of stimuli including telomere shortening, DNA damage, oncogenic stress and oxidative stress, suggesting their intimate relationship. Autophagy is originally thought to suppress cellular senescence by removing damaged macromolecules or organelles, yet recent studies also indicated that autophagy promotes cellular senescence by facilitating the synthesis of senescence-associated secretory proteins. These seemingly opposite roles of autophagy may reflect a complex picture of autophagic regulation on cellular senescence, including different types of autophagy or a unique spatiotemporal activation of autophagy. Thus, a better understanding of autophagy process will lead us to not only elucidate the conundrum how autophagy plays dual roles in the regulation of cellular senescence but also helps the development of new therapeutic strategies for many human diseases associated with cellular senescence. We address the pro-senescence and anti-senescence roles of autophagy while focusing on the potential mechanistic aspects of this complex relationship between autophagy and cellular senescence.

• The Journal of the Acoustical Society of Korea
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• v.29 no.2E
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• pp.55-63
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• 2010

High Intensity Focused Ultrasound (HIFU) is a noninvasive surgical method mainly targeting deeply located cancer tissue. Ultrasound is generated from an extemally located transducer and the beam is focused at the target volume, so that selective damage can be achieved without harm to overlying or surrounding tissues. The mechanism for cell killing can be combination of thermal and cavitational damage. Although cavitation can be an effective means of tissue destruction, the possibility of massive hemorrhage and the unpredictable nature of cavitational events prevent clinical application of cavitation. Hence, thermal damage has been a main focus related to HIFU research. 2D phased array transducer systems allow electronic scanning of focus, multi-foci, and anti-focus with multi-foci, so that HIFU becomes more applicable in clinical use. Currently, lack of noninvasive monitoring means of HIFU is the main factor to limit clinical applications, but development in MRI and Ultrasound Imaging techniques may be able to provide solutions to overcome this problem. With the development of advanced focusing algorithm and monitoring means, complete noninvasive surgery is expected to be implemented in the near future.

• Journal of Fashion Business
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• v.16 no.2
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• pp.124-137
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• 2012

This study aims to identify the meaning and formation cause of a style, and the essential elements of style formation, through psychobiological research as well as an analysis of the designs of Iris Van Herpen, a fashion designer, who in just 6 years has developed into a world-renowned new designer. As a result, it has been found that the psychobiological causes to form a style stem from the action of 'long-term memory', which is consolidated by 'selective attention', 'perceptional subjectivity', the principle of the 'neuron's connection specificity and invariance', and the principle of a 'neuronal signal's unilateral flow'. With such action, Herpen could develop her own original composition techniques. The formative shapes created by such composition techniques are characterized by enumeration, superposition, and hanging. The study has also found that the essential elements for a designer to be able to form his/her own style include 'aesthetic originality' in which the designer views the property of a thing from his/her inherent perspective, and finds the uniqueness from the thing that only he/she can express, 'technical differences' that are creative and original, and 'formative specificity' that is summarized into one property through an impressive shape.

• Electrical & Electronic Materials
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• v.8 no.6
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• pp.699-707
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• 1995

The material that is both conductive in electricity and transparent to the visible ray is called transparent conducting thin film. It has many fields of application such as Solar Cell, Liquid Crystal display, Vidicon on T.V, transparent electrical heater, selective optical filter, and a optical electric device , etc. In the recent papers on several TCO( transparent conducting oxide ) material, the study is mainly focusing on ITO(indium tin oxide) because ITO shows good results on both optical and electrical properties. Nowaday, in the development of LCD(Liquid Crystal display), the low temperature process to reduce the production cost and to deposit ITO on polymer substrate (or low melting substrate) has been demanded. In this study, we prepared indium tin oxide(ITO) by a cylindrical DC magnetron sputtering with Indium-tin (9:1) alloy target instead of indium-tin oxide target. The resistivity of the film deposited in oxygen partial pressure of 5% and substrate temperature of 140.deg. C. is 1.6*10$\^$-4/.ohm..cm with 85% optical transmission in viaible ray.

• Journal of Multimedia Information System
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• v.7 no.4
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• pp.249-256
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• 2020

Learning methods using various assistive and smart devices have been developed to enable independent learning of the disabled. Pointer control is the most important consideration for the disabled when controlling a device and the contents of an existing graphical user interface (GUI) environment; however, difficulties can be encountered when using a pointer, depending on the disability type; Although there are individual differences depending on the blind, low vision, and upper limb disability, problems arise in the accuracy of object selection and execution in common. A multimodal interface pilot solution is presented that enables people with various disability types to control web interactions more easily. First, we classify web interaction types using digital devices and derive essential web interactions among them. Second, to solve problems that occur when performing web interactions considering the disability type, the necessary technology according to the characteristics of each disability type is presented. Finally, a pilot solution for the multimodal interface for each disability type is proposed. We identified three disability types and developed solutions for each type. We developed a remote-control operation voice interface for blind people and a voice output interface applying the selective focusing technique for low-vision people. Finally, we developed a gaze-tracking and voice-command interface for GUI operations for people with upper-limb disability.

• Journal of Fashion Business
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• v.26 no.3
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• pp.98-115
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• 2022

The purpose of study was to analyze the process of accepting by BTS fans. The methodology used in this study was qualitative research using grounded theory and the results of the study follow. As a result of open coding, 47 concepts, 23 subcategories, and 14 categories were derived. In the axis coding stage, the casual conditions were "Recognition of BTS image," "Fascinated by BTS image," "Simple consumption of BTS image," and "Arising and expansion of curiosity about BTS image." The contextual conditions were "Accessibility of BTS image" and "Abundance of BTS image searching paths." The central phenomenon appeared to be "Immersing and studying BTS image." The arbitration conditions were "Capabilities required to reproduce BTS image" and "Motivation for contributing BTS image." The actions/interactions were "Presenting BTS image," "Contribution to the spread of BTS image," and "Involved in forming new BTS image." The result was "Emergence and expansion of new BTS image meaning" and "Strengthening attachment to BTS." Through process analysis, it was found that acceptance of BTS images consisted of five stages: "Recognition of BTS image," "Becoming curious about BTS image," "Searching BTS image," "Intervention of BTS image." and "Reproduction of BTS image." As a result of deriving the core categories through selective coding, the core category was "Forming a bond while participating in the BTS image."

• Anatomy and Cell Biology
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• v.56 no.2
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• pp.211-218
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• 2023

Despite several studies focusing on the facial arteries variable courses, the findings have significantly differed. The divergent findings have made it increasingly challenging to establish consistent correlations. Thus, as a vital artery, the facial artery is prone to numerous variations, which makes the identification of the variations vital to clinical practice, particularly for the orofacial and rhinoplastic surgery, and the increasingly selective chemotherapy procedures. The present research uses angiography images for analysis in studying the bilateral facial artery variations noted in patients undergoing carotid angiography for the evaluation of congenital anomalies, cerebral vascular malformations, and intra-arterial procedures. Conventional angiography was used, as it is a vital assessment tool that helps in the assessment of variations in the facial arteries and is suitable in evaluating smaller vascular anatomy, due to the perfect spatial resolution and portrayal of vascular anatomy. Thus, rather than normal ending of the facial artery as an angular artery, the study disclosed that in certain instances, the artery termination took the form of a superior labial artery with a small lateral nasal artery branch located closer to the midline compared to the normal cases. Also, the study has disclosed a conspicuous pre-masseteric branch with small branches originating from the infraorbital artery and providing potential compensation for the facial artery's shortness. Regardless of the infrequency of such variations, it is vital that they are considered during the performance of any facial surgical procedure.

• Childhood Kidney Diseases
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• v.28 no.2
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• pp.51-58
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• 2024

Patients with chronic kidney disease (CKD) bear a significant financial burden and face numerous complications and higher mortality rates. The progression of CKD is associated with glomerular injury caused by glomerular hyperfiltration and oxidative stress. Factors such as uncontrolled hypertension, elevated urine protein levels, anemia, and underlying glomerular disease, contribute to CKD progression. In addition to conservative treatment, several medications are available to combat the progression of CKD to end-stage kidney disease. Renin-angiotensin-aldosterone system blockers could slow the progression of CKD by reducing glomerular hyperfiltration, lowering blood pressure, and decreasing inflammation. Mineralocorticoid receptor antagonists inhibit the mineralocorticoid receptor signaling pathway, thereby attenuating inflammation and fibrosis. Sodium-glucose cotransporter 2 inhibitors exhibit protective effects on the kidneys and against cardiovascular events. Tolvaptan, a selective vasopressin V2-receptor antagonist, decelerates the rate of increase in total kidney volume and deterioration of kidney function in patients with rapidly progressive autosomal dominant polycystic kidney disease. The protective effects of AST-120 remain controversial. Due to a lack of evidence regarding the efficacy and safety of these medications in children, it is imperative to weigh the benefits and adverse effects carefully. Further research is essential to establish the efficacy and safety profiles in pediatric populations.