• 한국정보통신학회논문지
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• 제19권1호
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• pp.149-155
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• 2015

본 논문에서는 선형성이 개선된 5MHz의 샘플링 주파수를 가지는 10-비트 디지털/아날로그 변환기를 제안한다. 제안하는 디지털/아날로그 변환기는 10-비트 R-2R 기반 디지털/아날로그 변환기, rail-to-rail 입력 범위의 차동 전압증폭기를 이용하는 출력버퍼, 그리고 바이어스 전압을 위한 밴드-갭 기준전압 회로로 구성된다. R-2R 디지털/아날로그 변환기의 2R 구현에 스위치를 위해 사용되는 인버터의 turn-on 저항 값을 포함하여 설계함으로 선형성을 개선시킨다. DAC의 최종 출력 전압 범위는 출력버퍼에 차동전압증폭기를 이용함으로 R-2R의 rail-to-rail 출력 전압으로부터 $2/3{\times}VDD$로 결정된다. 제안된 디지털/아날로그 변환기는 1.2V 공급전압과 1-poly, 8-metal을 이용하는 130nm CMOS 공정에서 구현되었다. 측정된 디지털/아날로그 변환기의 동적특성은 9.4비트의 ENOB, 58dB의 SNDR, 그리고 63dBc의 SFDR이다. 측정된 DNL과 INL은 -/+0.35LSB 미만이다. 제작된 디지털/아날로그 변환기의 면적과 전력소모는 각각 $642.9{\times}366.6{\mu}m^2$과 2.95mW이다.

• 유통과학연구
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• 제12권8호
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• pp.113-121
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• 2014

Purpose - Recently, the number of corporations that practice environmental and social responsibility, besides engaging in traditional profit-seeking activities, has been growing steadily, as interest in Corporate Social Responsibility (CSR) is increasing. Recent research on CSR practices has identified the relationship between CSR activities and corporate value as one of the main issues in this respect. Considering that donations constitute a large proportion of a company's charitable activities, we considered the extent of donation expenses as a charitable activity in order to mitigate sample selection bias. Specifically, we analyzed the impact of donation expenses on firm value, while investigating if this impact varied in response to the level of corporate governance of firms. Research design, data, and methodology - We used non-financial firms listed on the Korean Stock Exchange, having their fiscal year end in December, and the sample period was 2006-2013. For the dependent variable, Tobin's q was used as the corporate value, and for the independent variable, donations were measured as the donation-expense-to-sales ratio. Corporate governance scores, as rated by the Korea Corporate Governance Service, were used to measure corporate governance levels because they consider the overall aspects of governance, including ownership structure, the board of directors, and the audit mechanism of individual companies. To examine the impact of donations on a company in relation to the level of corporate governance, we estimated regression models using the interaction terms of the governance dummy and donation variables. Then, we further estimated the regression models of two sub-samples that were classified according to the level of corporate governance. Similar to previous studies, the study uses variables that affect firm value, such as R&D expenditure, advertising expenses, EBITDA, debt-to-equity ratio, sales growth, company age, and company size as control variables. Results - The empirical results show that firm value significantly increased in response to an increase in donation expenses. Upon including the interaction terms of governance level dummy variables and donations, the coefficients of the interaction terms show significant positive values, while those of donation variables show significant negative values. In the strong governance sub-sample, the relationship between the donation expenses and corporate value was statistically positive (+) and significant. However, in the weak governance sub-sample, the relationship between the donation expenses and corporate value was statistically insignificant and negative (-). Conclusions - The empirical results suggest that donation expenses are significantly linked to an enhanced corporate value if firms have a good corporate governance structure. However, if the corporate governance structure is weak, the same relationship is not necessarily observed. The results of this study show that if a firm has high corporate governance, CSR practices enhance the company's reputation such that it has a positive (+) relationship with corporate value. If a firm has weak corporate governance, on the other hand, CSR practices are recognized as an agency cost and do not increase corporate value.

• Journal of Korean Neurosurgical Society
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• 제65권4호
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• pp.539-548
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• 2022

Objective : Although full-endoscopic lumbar interbody fusion (Endo-LIF) has been tried as the latest alternative technique to minimally invasive transforaminal lumbar interobody fusion (MIS-TLIF) since mid-2010, the evidence is still lacking. We compared the clinical outcome and safety of Endo-LIF to MIS-TLIF for lumbar degenerative disease. Methods : We systematically searched electronic databases, including PubMed, EMBASE, and Cochrane Library to find literature comparing Endo-LIF to MIS-TLIF. The results retrieved were last updated on December 11, 2020. The perioperative outcome included the operation time, blood loss, complication, and hospital stay. The clinical outcomes included Visual analog scale (VAS) of low back pain and leg pain and Oswestry disability index (ODI), and the radiological outcome included pseudoarthosis rate with 12-month minimum follow-up. Results : Four retrospective observational studies and one prospective observational study comprising 423 patients (183 Endo-LIF and 241 MIS-TLIF) were included, and the pooled data analysis revealed low heterogeneity between studies in our review. Baseline characteristics including age and sex were not different between the two groups. Operation time was significantly longer in Endo-LIF (mean difference [MD], 23.220 minutes; 95% confidence interval [CI], 10.669-35.771; p=0.001). However, Endo-LIF resulted in less perioperative blood loss (MD, -144.710 mL; 95% CI, 247.941-41.478; p=0.023). Although VAS back pain at final (MD, -0.120; p=0.586), leg pain within 2 weeks (MD, 0.005; p=0.293), VAS leg pain at final (MD, 0.099; p=0.099), ODI at final (MD, 0.141; p=0.093) were not different, VAS back pain within 2 weeks was more favorable in the Endo-LIF (MD, -1.538; 95% CI, -2.044 to -1.032; p<0.001). On the other hand, no statistically significant group difference in complication rate (relative risk [RR], 0.709; p=0.774), hospital stay (MD, -2.399; p=0.151), and pseudoarthrosis rate (RR, 1.284; p=0.736) were found. Conclusion : Relative to MIS-TLIF, immediate outcomes were favorable in Endo-LIF in terms of blood loss and immediate VAS back pain, although complication rate, mid-term clinical outcomes, and fusion rate were not different. However, the challenges for Endo-LIF include longer operation time which means a difficult learning curve and limited surgical indication which means patient selection bias. Larger-scale, well-designed study with long-term follow-up and randomized controlled trials are needed to confirm and update the results of this systematic review.

• 지식경영연구
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• 제23권4호
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• pp.177-205
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• 2022

중소기업은 상대적으로 작은 규모와 제한된 자원으로 인해 혁신의 효율성과 효과성을 높이기 위해 개방형 혁신에 참여한다. 기존 연구들은 중소기업이 수행하는 다양한 유형의 개방형 혁신활동의 성과효과를 연구하였으나, 특히 결합형 개방형 혁신활동의 성과효과에 대한 결과가 혼재한 상황이다. 이에 본 연구는 중소기업의 결합형 개방형 혁신협력활동을 'R&D 협력활동'과 'R&D 이외의 협력활동'으로 세분화하여, 각 활동이 기업의 혁신성과와 재무성과에 미치는 효과를 Heckman의 2단계 모형을 적용하여 검정하였다. 분석 데이터로는 과학기술정책연구원(STEPI) 주관의 국가승인통계인 '2020년 한국기업혁신조사: 제조업 부문' 자료를 활용하였다. 분석결과 중소기업의 R&D 협력활동은 시장최초 상품혁신 성과에만 유의미한 정(+)의 효과가 있고, R&D 이외의 협력활동은 상품혁신, 비즈니스프로세스혁신, 시장최초 상품혁신, 자사최초 상품혁신 모두에 유의미한 정(+)의 효과가 있는 것으로 나타났다. 하지만 두 유형의 혁신협력활동 모두 재무성과에는 유의미한 효과가 없는 것으로 나타났다. 또한 이러한 혁신협력활동의 성과효과는 중소기업 내에서도 기업규모에 따라 다른 것으로 나타났다. 본 연구는 중소기업 맥락의 개방형 혁신 연구에 이론적으로 기여하며, 중소기업 경영자의 혁신전략 수립 및 관련 정책입안자의 정책 방향 도출에 참고가능한 지침을 제공한다.

• 대한한방내과학회지
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• 제44권3호
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• pp.387-401
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• 2023

Objective: This study was conducted to investigate the preventive effect of herbal medicines on restenosis after percutaneous coronary intervention (PCI) by reviewing randomized controlled trials (RCTs). Methods: RCTs were searched for herbal medicine treatment after PCI using eight online databases (PubMed, CNKI, Wanfang, J-STAGE, OASIS, ScienceON, KTKP, and KISS). Studies that confirmed restenosis through coronary angiography at follow-up were selected according to the inclusion and exclusion criteria. The primary outcome was the restenosis rate, and the secondary outcome was the angina recurrence rate. Data were extracted from the final selected studies according to the research methodology and then analyzed with Review Manager 5.4.1. Study quality was assessed using Cochrane's risk-of-bias (RoB) tool. Results: Of the 252 papers obtained through the primary search, nine studies that met the selection criteria were finally selected. In these nine studies, herbal medicine combined with western medicine was used for the experimental group, and western medicine treatment was used alone for the control group. The meta-analysis result revealed that the restenosis rate and angina recurrence rate were significantly lower in the experimental group than in the control group (RR=0.34, 95% CI: 0.22-0.53, p<0.00001, I²=0% and RR=0.47, 95% CI: 0.29-0.78, p=0.004, I²=0%, respectively). Furthermore, the quality of studies assessed by Cochrane's RoB was low. Conclusions: This study showed that the combined treatment of herbal medicine and western medicine was effective in preventing restenosis and angina after PCI. As the number of papers included in this study was small, a large number of high-quality clinical studies should be considered in the future.

• 한국농림기상학회지
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• 제12권1호
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• pp.36-44
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• 2010

본 연구는 입지환경 인자를 적용하여 수종별 지위지수 추정식을 개발하고 이를 통해 해당 입지의 산림생산력을 추정함으로서 산불 피해지의 복구을 위한 수종 선택에 필요한 정보를 제공하고자 하였다. 이를 위해 입지환경 인자를 이용하여 동해안 산불 피해지역인 강릉, 고성, 동해, 그리고 삼척 지역에 적용할 수 있는 온대 중부지역의 수종별 지위지수 추정식을 조제하였다. 본 연구에서 도출된 수종별 지위지수 추정식은 4~5개의 비교적 소수의 입지환경 인자를 이용하여 산림생산력에 대한 높은 추정능력을 보였다. 또한 이와 같이 개발된 수종별 지위지수 추정식을 대상으로 모형의 평균 편의, 정도, 표준오차 등의 3가지 평가통계량에 근거한 검증을 실시한 결과 수종별 오차가 모두 0.5m 이내로 본 연구에서 도출된 지위지수 추정식의 실용성을 입증할 수 있었다. 지위지수 추정식의 검증결과를 보면전반적으로 본 연구에서 개발된 수종별 지위지수 추정식의 평가통계량은 낮은 것으로 판명되어 실제 적용하는 데는 문제가 없는 것으로 평가되었다. 본 연구에서 개발한 수종별 지위지수 추정식은 몇가지의 입지환경 인자만으로 산불 피해지에 대한 수종별 산림생산력을 추정할 수 있는 것으로 판명되어 앞으로 활용가치가 높을 것으로 평가된다. 특히 본 연구에서 얻어진 결과는 수종별 적지판정과 이를 통한 산림의 경영 및 관리에 유용한 정보로 활용될 수 있을 것으로 기대된다. 산불 피해지역의 입지평가 기준을 설정하기 위해서는 우선 산불피해임지를 자연회복, 인공복구 방법으로 현재의 임지를 개선하고자 할 때 이를 위한 입지 및 토양환경 인자 및 기준에 따라 임지의 생산력을 고려하여 적정한 수종을 선정하여 복구를 하여야 할 것이다. 본 연구에서는 입지환경 인자에 의한 임지생산력 추정결과 물푸레나무와 굴참나무의 적지가 비교적 넓은 면적으로 분석되어 침엽수의 단순림이 많이 있는 동해안 지역의 임분을 참나무류와 같은 활엽수 수종으로 임분 구조를 개선하여 산불이 수관화로 확산되는 큰 피해를 막을 수 있을 뿐만 아니라 산불의 피해를 저감하는 내화수림대의 역할을 할 수 있을 것으로 판단된다.

• Asia pacific journal of information systems
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• 제22권3호
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• pp.53-74
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• 2012

A challenge in fostering virtual communities is the continuous supply of knowledge, namely members' willingness to contribute knowledge to their communities. Previous research argues that giving away knowledge eventually causes the possessors of that knowledge to lose their unique value to others, benefiting all except the contributor. Furthermore, communication within virtual communities involves a large number of participants with different social backgrounds and perspectives. The establishment of mutual understanding to comprehend conversations and foster knowledge contribution in virtual communities is inevitably more difficult than face-to-face communication in a small group. In spite of these arguments, evidence suggests that individuals in virtual communities do engage in social behaviors such as knowledge contribution. It is important to understand why individuals provide their valuable knowledge to other community members without a guarantee of returns. In virtual communities, knowledge is inherently rooted in individual members' experiences and expertise. This personal nature of knowledge requires social interactions between virtual community members for knowledge transfer. This study employs the social capital theory in order to account for interpersonal relationship factors and identity theory for individual and group factors that may affect knowledge contribution. First, social capital is the relationship capital which is embedded within the relationships among the participants in a network and available for use when it is needed. Social capital is a productive resource, facilitating individuals' actions for attainment. Nahapiet and Ghoshal (1997) identify three dimensions of social capital and explain theoretically how these dimensions affect the exchange of knowledge. Thus, social capital would be relevant to knowledge contribution in virtual communities. Second, existing research has addressed the importance of identity in facilitating knowledge contribution in a virtual context. Identity in virtual communities has been described as playing a vital role in the establishment of personal reputations and in the recognition of others. For instance, reputation systems that rate participants in terms of the quality of their contributions provide a readily available inventory of experts to knowledge seekers. Despite the growing interest in identities, however, there is little empirical research about how identities in the communities influence knowledge contribution. Therefore, the goal of this study is to better understand knowledge contribution by examining the roles of social capital and identity in virtual communities. Based on a theoretical framework of social capital and identity theory, we develop and test a theoretical model and evaluate our hypotheses. Specifically, we propose three variables such as cohesiveness, reciprocity, and commitment, referring to the social capital theory, as antecedents of knowledge contribution in virtual communities. We further posit that members with a strong identity (self-presentation and group identification) contribute more knowledge to virtual communities. We conducted a field study in order to validate our research model. We collected data from 192 members of virtual communities and used the PLS method to analyse the data. The tests of the measurement model confirm that our data set has appropriate discriminant and convergent validity. The results of testing the structural model show that cohesion, reciprocity, and self-presentation significantly influence knowledge contribution, while commitment and group identification do not significantly influence knowledge contribution. Our findings on cohesion and reciprocity are consistent with the previous literature. Contrary to our expectations, commitment did not significantly affect knowledge contribution in virtual communities. This result may be due to the fact that knowledge contribution was voluntary in the virtual communities in our sample. Another plausible explanation for this result may be the self-selection bias for the survey respondents, who are more likely to contribute their knowledge to virtual communities. The relationship between self-presentation and knowledge contribution was found to be significant in virtual communities, supporting the results of prior literature. Group identification did not significantly affect knowledge contribution in this study, inconsistent with the wealth of research that identifies group identification as an important factor for knowledge sharing. This conflicting result calls for future research that examines the role of group identification in knowledge contribution in virtual communities. This study makes a contribution to theory development in the area of knowledge management in general and virtual communities in particular. For practice, the results of this study identify the circumstances under which individual factors would be effective for motivating knowledge contribution to virtual communities.

• Journal of Gastric Cancer
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• 제20권2호
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• pp.152-164
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• 2020

Purpose: To compare long-term disease-free survival (DFS) between patients receiving tegafur/gimeracil/oteracil (S-1) or capecitabine plus oxaliplatin (CAPOX) adjuvant chemotherapy (AC) for gastric cancer (GC). Materials and Methods: This retrospective multicenter observational study enrolled 983 patients who underwent curative gastrectomy with consecutive AC with S-1 or CAPOX for stage II or III GC at 27 hospitals in Korea between February 2012 and December 2013. We conducted propensity score matching to reduce selection bias. Long-term oncologic outcomes, including DFS rate over 5 years (over-5yr DFS), were analyzed postoperatively. Results: The median and longest follow-up period were 59.0 and 87.6 months, respectively. DFS rate did not differ between patients who received S-1 and CAPOX for pathologic stage II (P=0.677) and stage III (P=0.899) GC. Moreover, hazard ratio (HR) for recurrence did not differ significantly between S-1 and CAPOX (reference) in stage II (HR, 1.846; 95% confidence interval [CI], 0.693-4.919; P=0.220) and stage III (HR, 0.942; 95% CI, 0.664-1.337; P=0.738) GC. After adjustment for significance in multivariate analysis, pT (4 vs. 1) (HR, 11.667; 95% CI, 1.595-85.351; P=0.016), pN stage (0 vs. 3) (HR, 2.788; 95% CI, 1.502-5.174; P=0.001), and completion of planned chemotherapy (HR, 2.213; 95% CI, 1.618-3.028; P<0.001) were determined as independent prognostic factors for DFS. Conclusions: S-1 and CAPOX AC regimens did not show significant difference in over-5yr DFS after curative gastrectomy in patients with stage II or III GC. The pT, pN stage, and completion of planned chemotherapy were prognostic factors for GC recurrence.

• 대한골관절종양학회지
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• 제16권1호
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• pp.14-20
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• 2010

목적: 지방육종의 국소재발과 원격전이 및 무병생존율에 영향을 미치는 예후인자들에 대해 알아보고자 하였다. 대상 및 방법: 1993년 이후 치료받은 52명의 지방육종 환자들을 대상으로 진단시 연령, 종양의 크기, 발생 부위, 조직학적 유형, 조직학적 악성도, 절제 유형, 수술적 절제연, 항암화학요법 및 방사선 치료가 국소재발, 원격 전이 그리고 무병생존율에 미치는 영향을 분석하였다. 평균 추시기간은 39개월이었고 통계적 분석에는 단일변수 및 다중변수 회귀분석을 이용하였다. 결과: 국소 재발이 11예(21.2%)에서 발생하였으며 원격전이는 4예(8%)에서 발생하였다. 지속적 무병생존율은 술 후 4년에 67%였다. 단일변수 분석에서 조직학적 악성도, 절제연, 항암화학요법, 방사선 치료가 국소재발과 관련이 있었으나(p<0.05) 다중변수 분석에서는 절제연과 항암화학요법, 방사선 치료가 불량한 예후인자로 나타났다. 종양이 체간에서 발생한 경우 통계적으로 유의하게 원격 전이율이 높았다(p<0.05). 무병생존율에 대한 단일변수 분석에서는 조직학적 악성도 및 항암화학요법이 유의한 차이를 보였으나(p<0.05) 다중변수 분석에서는 유의한 인자가 없었다. 결론: 선택오차를 고려할 때 절제연 양성이 국소재발의 불량한 예후인자였으며 종양이 체간에서 발생한 경우 원격 전이율이 높았다. 무병생존율과 관련하여서는 유의한 인자가 없었다.

• Journal of Yeungnam Medical Science
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• 제8권2호
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• pp.150-157
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• 1991

보건연구개발 사업을 위한 지역사회 진단의 일환으로 도시 영세지역 주민을 대상으로 시행한 건강진단 조사의 결과를 요약하면 다음과 같다. 전체 대상주민 2,591명중 건강진단에 참여한 영세지역 주민은 437명(16.9%)였으며 남자는 9.9% 여자는 23.9%가 참여하였다. 연령별로는 60세 이상군이 42%로 가장 높은 참여율을 나타냈고 20-29세군이 5.9%로 가장 낮았다. 건강진단에서 이상소견율은 남자가 38.7%, 여자가 45.8%였으며 전체적으로 43.7%였고 연령별로는 60세 이상군이 69.8%로 가장 높고 10-19세군이 10.9%로 가장 낮았다. 국제질병분류(ICD 17 대분류)에 의한 질병분포는 소화기계 질병이 23.7%로 가장 높았고 순환기계 질병 19.7%, 신경계 및 감각기 질병 13.2% 순이었다. Screening test에서 헤마토크릿치가 낮은 경우가 14.6%, 고혈압이 10.1%, 청력손실 5.5%, 간기능이상 4.1%, 당뇨가 2.3%, 단백뇨가 1.4%, chest X-선상 이상소견이 0.9%였다.