• 해양환경안전학회지
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• 제24권6호
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• pp.735-749
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• 2018

본 연구에서는 우리나라의 주요하천인 한강, 금강, 영산강, 섬진강 그리고 낙동강의 하구에서 해수중 화학적산소요구량(COD)의 농도를 결정하는 주요 요인과 수질인자에 대해 고찰하였다. 주성분분석으로 얻어진 해수중 COD 농도를 결정하는 주요요인은 염분과 클로로필-a를 중심으로 한 외래성 기원과 자생공급으로 나타났으며, 그 외 해저 퇴적층의 유기물도 영향을 미치는 것으로 나타났다. 하구해역의 COD 농도를 결정하는 수질인자들의 기여도는 회귀식 기울기를 통해 평가하였다. 조사시기별로는 전체적으로 염분의 영향을 많이 받는 것으로 나타났으며, 4월과 8월에는 클로로필-a의 영향도 함께 받는 것으로 나타났다. 하구별로는 낙동강에서는 클로로필-a, 한강과 영산강에서는 염분, 금강에서는 염분과 함께 클로로필-a의 기여도가 각각 큰 것으로 나타났으며, 섬진강에서는 염분과 클로로필-a 모두 낮은 기여를 나타내었다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6227-6231
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• 2013

In the past, hepatitis B virus (HBV) infection was endemic in the general Korean population. The association of HBV infection with the occurrence of liver cancer has been well demonstrated in several epidemiologic studies. While the mortality rates of liver cancer in Korea have decreased steadily over the last decade, the presence of hepatitis B surface antigen (HBsAg) in mothers remains high at 3-4%, and 25.5% of these HBsAg positive mothers are positive for hepatitis B e antigen (HBeAg). HBV infection caused almost a quarter of hepatocellular carcinoma (HCC) cases and one-third of deaths from HCC. These aspects of HBV infection prompted the Korean government to create a vaccination program against HBV in the early 1980s. In 1995, the Communicable Disease Prevention Act (CDPA) was reformed, and the government increased the number of HBV vaccines in the National Immunization Program (NIP), driving the vaccination rate up to 95%. In 2000, the National Health Insurance Act (NHIA) was enacted, which provided increased resources for the prevention of perinatal HBV infection. Then in 2002, the Korean government, in conjunction with the Korean Medical Association (KMA), launched an HBV perinatal transmission prevention program. The prevalence of HBsAg in children had been high (4-5%) in the early 1980s, but had dropped to below 1% in 1995, and finally reached 0.2% in 2006 after the NIP had been implemented. After the success of the NIP, Korea finally obtained its first certification of achievement from the Western Pacific Regional Office of the World Health Organization (WPRO-WHO) for reaching its goal for HBV control. An age-period-cohort analysis showed a significant reduction in the liver cancer mortality rate in children and adolescents after the NIP had been implemented. In addition to its vaccination efforts, Korea launched the National Cancer Screening Program (NCSP) for 5 leading sites of cancer, including the liver, in 1999. As a consequence of this program, the 5-year liver cancer survival rate increased from 13.2% (1996-2000) to 23.3% (2003-2008). The development of both the primary and secondary prevention for liver cancer including HBV immunization and cancer screening has been of critical importance.

• 디지털융복합연구
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• 제15권8호
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• pp.1-14
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• 2017

이 연구는 근린 보행안전 개선에 필요한 체계적 진단 매뉴얼을 개발하고, 사례연구를 통하여 매뉴얼의 구체적 적용과정과 유용성을 보여주는 것을 주목적으로 기술적 탐색적 연구이다. 선행연구 검토를 통해 개발한 진단 매뉴얼은 간접자료를 활용하는 도면/데이터 분석, 조사원에 의한 현장관찰, 그리고 주민을 대상으로 하는 이용자 설문인터뷰의 세가지 조사방법을 포함하는 혼합연구방법을 채택하고 있다. 저자는 서울 창신동 대상으로 진단 매뉴얼을 적용한 사례연구에서 세 가지 조사방법에 따른 연구결과들을 통합적으로 분석하여 대상지 내 위험지역과 위험요인들을 체계적으로 도출하는 과정을 구체적으로 기술함으로써 진단 매뉴얼의 유용성을 보여주었다. 이 연구는 실무적으로는 계획가들에게 근린 보행안전성 진단을 위한 체계적 수단을 제공했다는 점에서, 학술적으로는 여러 조사방법 간의 차이를 비교하고 통합적인 결론을 도출하는 삼각검증 프로세스를 실증적으로 보여줬다는 점에서 의의를 갖는다. 후속연구에서는 진단 매뉴얼을 더 많은 사례들에 적용하여 봄으로써 다양한 맥락에서 보다 정교하게 작동할 수 있도록 개선할 계획이다.

• 융합정보논문지
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• 제10권5호
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• pp.177-187
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• 2020

본 연구는 65세 이상 노인의 돌봄요구군을 분류하고, 군간 특성을 확인하기 위하여 수행되었다. 한국보건사 회연구원이 진행한 '2017년도 노인실태조사'의 자료를 이용한 이차자료 분석연구로, 분석대상은 2017년 노인실태 조사 참여자 중 서울시 노인 999명, 가중치 부여 1,295,491명이다. 돌봄요구군의 분류를 위하여, 의료요구, 일상생활수행 지원요구, 사회적 활동 지원요구의 특성을 파악하였다. 지원요구가 하나도 없는 일반군이 50.4%, 의료요구군이 17.9%, 일상생활수행 지원요구 또는 사회적 활동 지원요구가 있는 복지요구군이 14.2%, 의료요구와 복지요구가 모두 있는 복합요구군이 17.5%이었다. 성별, 흡연, 치매검진, 지난 1년간 외래이용, 일상생활수행 도움 여부, 비동거 자녀 또는 손녀 여부를 제외한 일반적 특성, 장기요양등급 및 장애등급 현황, 경제적 부담 및 일상생활 도움 정도, 건강행태와 건강상태, 삶의 만족도에서 돌봄요구군간 유의미한 차이를 보였다(p<.001). 복합요구군에게 의료와 복지의 통합돌봄 서비스를 우선 제공해야 한다. 특히 복합요구군은 의료, 복지, 운동, 영양, 정신건강, 간호의 요구를 모두 가지고 있는 대상자로 다학제적 팀 접근이 필요하다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.93-93
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• 2017

To develop rice cultivars with increased biomass and grain yield, superior lodging resistance is an essential trait. The new breeding approach can be adopted for the improvement of stem lodging resistance by enhancing culm strength. The resistance to breaking type lodging is attributed to bending moment of basal culm (M), which is composed of the section modulus (SM) and bending stress (BS). The resistance to the bending type lodging is attributed to flexural rigidity (FR) of stem, which is composed of the secondary moment of inertia (SMI) and Young's modulus (YM). Starch and cell wall components such as cellulose, hemicellulose and lignin also play a significant role in physical strength of culm, and thus affect lodging. Leaf Star has a superior lodging resistance due to its thick and stiff culm because of its high M and FR compared with Koshihikari. Furthermore, Leaf Star contains high densities of hemicellulose, cellulose and low lignin density in culm compared with Koshihikari. In this study, we performed QTL analysis for these traits associated with culm strength, using 94 recombinant inbred lines (RILs, $F_8$), derived from a cross between Leaf Star and Koshihikari. The SM in the RILs showed a continuous distribution. QTLs for SM were detected on chrs.2, 3 and 10. Leaf Star alleles increased SM on chrs. 2 and 3, but Koshihikari allele increased on chr.10. These QTLs overlapped with those QTLs identified using backcrossed inbred line derived from a cross between Chugoku 117 and Koshihikari, the parents of Leaf Star. The FR in Leaf Star was higher than that in Koshihikari due to the larger SMI and YM. 3 QTLs for SMI were detected on chrs.2, 3 and 10. Leaf Star alleles increased SMI on chrs.2 and 3, and Koshihikari alleles increased on chr.10. One QTL on chr.3 and two QTLs on chr.5 for hollocelulose content were detected with Leaf Star alleles contribution. Moreover, two QTLs were detected for hemicellulose density on chrs.3 and 5. Leaf Star allele increased hemicellulose density on chr.5, and Koshihikari allele increased on chr.3. Furthermore, two QTLs for cellulose density were detected on chr.5, and one QTL on chr.2. For starch content, one QTL on chr.3 and two QTLs on chr.5 with Leaf Star alleles contribution were detected. TULK-6 carrying a chromosome segment of Leaf Star on chr.5 in the Koshihikari genetic background showed higher densities of starch and hemicellulose than those in Koshihikari. These results suggest that the detected QTLs for culm strength could be utilized for the improvement of lodging resistance in rice by marker-assisted selection.

• 자원환경지질
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• 제34권1호
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• pp.71-88
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• 2001

경상지역에서 산출되는 탄산약수 중 신촌약수에 대하여 지화학적 및 동위원소 연구를 수행하였다. 신촌 탄산약수는 높은 $CO_2$분압 ($10^{-0.35}$ ~$10^{0.29}$ atm) 및 높은 총용존이온함량 (835~3,144 mg/L)을 가진 전형적인 탄산수 특성을 보이며 지화학적으로는 Ca (Na)-HCO$_3$형으로 분류된다. 지화학 및 환경동위원소 분석결과는 탄산수내 이산화탄소가 심부기원임을 지시한다. 따라서 심부기원의 $CO_2$에 의해 생성된 탄산수가 다양한 물-암석 반응을 거치면서 주로 심부의 화강암과 반응에 의해 현재의 탄산수로 진화된 것으로 판단된다. 주된 물-암석 반응은 사장석과의 반응이며 방해석의 침전이 수반되면서 Ca의 용존량이 조절되어 Na의 함량이 높아진 것으로 보인다. 이처럼 탄산수의 지화학적 특성은 주로 심부의 화강암과 반응에 의한 특징을 보여주지만 높은 K 및 $SO_4$함량으로 미루어 탄산수가 지표로 상승하는 과정에서 주변모암인 퇴적암과의 반응에 의해서도 일부 영향받은 것으로 추정된다. 또한 탄산수 내 $NO_3$함량 및 삼중 수소함량은 일반 천부지하수의 혼입가능성을 지사하고 있다. 신촌지역 자연수들의 산소 및 수소 동위원소 조성은 전체적으로 지구순환수선과 평행하게 도시되어 순환수 기원으로 추정할 수 있으며, 일부 $CO_2$분압이 높은 탄산수 시료는 동위원소적으로 더 가벼운 $CO_2$가스와 동위원소적으로 재평형을 이루었음을 보여주기도 한다. 탄산수의 탄소 동위원소 조성은 전체적으로 심부기원 $CO_2$의 영역에 해당되며, 심부기원 $CO_2$영역내에서 동위원소적으로 무거운 영역에 속하는 특징을 보인다.

• 농촌계획
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• 제23권1호
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• pp.53-63
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• 2017

Although some indicators for evaluating rural settlement conditions have been offered, these indicators could not reflect unique characteristics that rural has its own peculiarities. The rural area is identified with central districts functioned as service provision and hinterlands used its service. The aim of this study is to find a central district of rural villages and define range of its hinterlands using various physical characteristics of rural areas. Targeting areas are Yongsan and Hwanggan in Yeongdong-gun. The physical characteristics are represented by building density, number of shops among secondary and tertiary industries, official land price, and density of bus line. The rural central district is estimated by linear programming using defined the physical characteristics. Also its hinterlands used Huff model and social accessibility. The results of this study are as follows; (1) The physical characteristics in Hwanggan myeon is higher than Yongsan myeon because Hwanggan area has a large floating population for using Hwanggan station and ticket office; (2) The central district in Hwanggan has wider regional range than Yongsan. When central district estimate in rural areas, we suggest a grid diameter of Hexagon for controlling errors; (3) Considering accessibility, the life zone of 4 districts defined legally in Hwanggan use Yongsan and 2 legal districts in Hwanggan are possible to take advantage of Yongsan's life zone; (4) The results of survey targeting boundary villages between Yongsan and Hwanggan, individual drivers use central districts both Yongsan and Hwanggan, however users by public transportation (especially bus) go more to Hwanggan because bus lines to Hwanggan have many routes than to Yongsan. Evaluating the rural settlement conditions by national unit through grasping central districts and its hinterlands, these results can use as base line data and the evidence for regional development projects.

• 한국학교보건학회지
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• 제10권1호
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• pp.41-50
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• 1997

The purpose of this study is to provide fundamental data supporting facilitation of a formal health education performed by school nurses as health educators. To evaluate the teacher expertise of school nurses as health educators, this study analyzed the present status of health education and the recognition of self-confidence in teaching ability of school nurses. Self addressing questionnaire were mailed out to 340 secondary school nurses in Seoul and out of them 244 nurses (71.8%) responded to the survey. Analysis of the data was made using t-test and ANOVA in SAS program. The major results are as follows : 1. The total health instruction performance rate was 84.6% (204). Regular health instruction was carried out by 66 nurses and the rest of the 155 subjects gave irregular instruction on health education. 2. Regular health education classes was offered as a part of physical education class hour by 89.4% of the respondents whereas only 10.6% of them had formal health education classes. The survey showed that irregular health education classes were mainly held in physical education class hours (70.3%) and 14.8% had opportunities for additional classes on health education. 3. The average class for regular health education was 5 hours per week but for irregular health education classes were only one hour per semester (32.9%). 4. Among the 11 categories of health education, education on drug abuse and body structure and function and physical development occupied 95.6%, 69.6% respectably while physical training, family health, social health occupied 10.8%, 12.7%. 5. Health education was given much more at public schools (88.2%) than at private schools. 6. 232 (95.0%) school nurses agreed with the necessity of formalizing health education classes and 227 (93.1%) wanted to change their status from school nurses to formal health teachers. 7. There is a tendency to change the status from school nurse to formal health teacher, and the necessity of having a formal curriculum on health education while less recognized by the older and longer-careered nurses was more recognized by those nurses with higher education. 8. The lack of administrative support (79.5%), work burden (77.9%), and lack of teaching competency (22.1%) were the greatest problems. 9. Education on drug abuse was stressed the most whereas physical training was most neglected. 10. There is a tendency that older and longer-careered school nurses thought less positively of their status, and then 98 (81.1%) school nurses acknowledged themselves as professional teachers. 11. 176 (72.5%) school nurses agreed with the necessity of continuing education : health knowledge and teaching skills for formal health teachers. 12. 179 (73.8%) school nurses had a positive attitude and undergraduate preparation and the practice of professional health teachers. 13. The school nurses had self-confidence in their teaching competence, teaching strategies and knowledge in all 11 health education areas.

• 한국식품위생안전성학회지
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• 제31권3호
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• pp.194-200
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• 2016

돼지고기 중 5종의 곰팡이독소(아플라톡신 $B_1$, $B_2$, $G_1$, $G_2$ 및 오크라톡신 A)를 분석하기 위해 0.1% 개미산을 함유한 50% 아세토니트릴용액으로 추출한 후 고체상추출칼럼을 이용하여 정제하고, LC-MS/MS로 동시 정량할 수 있는 시험법을 마련하였다. 분석조건으로 측정한 5종의 곰팡이독소 matrix-matched 표준곡선식에서 모두 상관계수 0.998이상의 상관관계를 나타내었다. 5종의 곰팡이독소 2배의 정량한계에서 10배의 정량한계로 첨가한 시료에서 평균 회수율은 72.1~109.9%로 실험 결과들이 EU 가이드라인에서 제시하는 유효성 확인을 위한 기준을 만족함으로써 시험법의 신뢰성을 확보할 수 있었다. 충청지역 유통되고 있은 돼지고기 20건에 대한 총아플라톡신 및 오크라톡신A에 대한 오염도 조사결과 정량한계 미만으로 조사되었다.

• Tuberculosis and Respiratory Diseases
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• 제81권3호
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• pp.247-255
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• 2018

Background: Patients with acute respiratory failure secondary to tuberculous destroyed lung (TDL) have a poor prognosis. The aim of the present retrospective study was to develop a mortality prediction model for TDL patients who require mechanical ventilation. Methods: Data from consecutive TDL patients who had received mechanical ventilation at a single university-affiliated tertiary care hospital in Korea were reviewed. Binary logistic regression was used to identify factors predicting intensive care unit (ICU) mortality. A TDL on mechanical Ventilation (TDL-Vent) score was calculated by assigning points to variables according to ${\beta}$ coefficient values. Results: Data from 125 patients were reviewed. A total of 36 patients (29%) died during ICU admission. On the basis of multivariate analysis, the following factors were included in the TDL-Vent score: age ${\geq}65$ years, vasopressor use, and arterial partial pressure of oxygen/fraction of inspired oxygen ratio <180. In a second regression model, a modified score was then calculated by adding brain natriuretic peptide. For TDL-Vent scores 0 to 3, the 60-day mortality rates were 11%, 27%, 30%, and 77%, respectively (p<0.001). For modified TDL-Vent scores 0 to ${\geq}3$, the 60-day mortality rates were 0%, 21%, 33%, and 57%, respectively (p=0.001). For both the TDL-Vent score and the modified TDL-Vent score, the areas under the receiver operating characteristic curve were larger than that of other illness severity scores. Conclusion: The TDL-Vent model identifies TDL patients on mechanical ventilation with a high risk of mortality. Prospective validation studies in larger cohorts are now warranted.