• Proceedings of the Korean Society for Bioinformatics Conference
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• 2005.09a
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• pp.287-293
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• 2005

Predicting RNA secondary structure as accurately as possible is very important in functional analysis of RNA molecules. However, different prediction methods and related parameters including terminal GU pair of helices, minimum length of helices, and free energy systems often give different prediction results for the same RNA sequence. Then, which structure is more important than the others? i.e. which combinations of the methods and related parameters are the optimal? In order to investigate above problems, first, three prediction methods, namely, random stacking of helical regions (RS), helical regions distribution (HD), and Zuker's minimum free energy algorithm (ZMFE) were compared by taking 1139 tRNA sequences from Rfam database as the samples with different combinations of parameters. The optimal parameters are derived. Second, Zuker's dynamic programming method for prediction of RNA secondary structure was revised using the above optimal parameters and related software BJRNAFold was developed. Third, the effects of short-range interaction were studied. The results indicated that the prediction accuracy would be improved much if proper short-range factor were introduced. But the optimal short-range factor was difficult to determine. A user-adjustable parameter for short-range factor was introduced in BJRNAFold software.

• Journal of Power Electronics
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• v.12 no.3
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• pp.377-386
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• 2012

An interleaved bridgeless buck-boost AC/DC converter is presented in this paper to achieve the characteristics of low conduction loss, a high power factor and low harmonic and ripple currents. There are only two power semiconductors in the line current path instead of the three power semiconductors in a conventional boost AC/DC converter. A buck-boost converter operated in the boundary conduction mode (BCM) is adopted to control the active switches to achieve the following characteristics: no diode reverse recovery problem, zero current switching (ZCS) turn-off of the rectifier diodes, ZCS turn-on of the power switches, and a low DC bus voltage to reduce the voltage stress of the MOSFETs in the second DC/DC converter. Interleaved pulse-width modulation (PWM) is used to control the switches such that the input and output ripple currents are reduced such that the output capacitance can be reduced. The voltage doubler topology is adopted to double the output voltage in order to extend the useable energy of the capacitor when the line voltage is off. The circuit configuration, principle operation, system analysis, and a design example are discussed and presented in detail. Finally, experiments on a 500W prototype are provided to demonstrate the performance of the proposed converter.

• Journal of Microbiology
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• v.35 no.1
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• pp.40-46
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• 1997

The pWHM220 cosmid with a 24-kb insert cloned from Streptomyces albus ATCC 21838 induces the biosynthesis of a polysther antibiotic similar to salinomycin in Streptomyces invidans. We have analyzed this region by DNA sequencing as well as Southern blot hybridization with type I and type II polyketide synthase (PKS) probes. Surprisingly, we found another set of type II SKS genes only 10-kb from the original PKS genes, salABCDE. The DNA sequence revealed two complete open reading frames (ORFs) named salB2 and salC2, and one partial ORF that does not resemble any known DNA or deduced protein sequence. The salC2 should code for chain length determining factor while the deduced amino acid sequence encoded by salB2 exhibits high similarity to .betha.-ketoacyl synthase from different PKS gene clusters. The highest identity was found for .betha.-keetoacyl synthases from S. argillaceus (MtmP. 59.1% identity), the mithramycin producer and from S. venezuelae ISP5230 (JadA, 52.3% identity), the jadomycin producer. The SalC2 protein clearly resembles its counterparts in order aromatic PKS gene clusters that are believed to influence the length of the polyketide chain. The highest identities observed were to that of S. argillaceus (MtmK, 62.3%) and S. venezuelae ISP 5230 (JadB, 55.1%) proteins, Moreover, the deduced amino acid sequences of the salB2 and salC2 products were 29.0% identical.

• Smart Structures and Systems
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• v.16 no.5
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• pp.919-935
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• 2015

The Hilbert-Huang transform (HHT) consists of empirical mode decomposition (EMD) and Hilbert spectral analysis. EMD has been successfully applied for identification of mode shapes of structures based on input-output approaches. This paper aims to extend application of EMD for output-only identification of mode shapes of linear structures. In this regard, a new simple and efficient method based on band-pass filtering and EMD is proposed. Having rather accurate estimates of modal frequencies from measured responses, the proposed method is capable to extract the corresponding mode shapes. In order to evaluate the accuracy and performance of the proposed identification method, two case studies are considered. In the first case, the performance of the method is validated through the analysis of simulated responses obtained from an analytical structural model with known dynamical properties. The low-amplitude responses recorded from the UCLA Factor Building during the 2004 Parkfield earthquake are used in the second case to identify the first three mode shapes of the building in three different directions. The results demonstrate the remarkable ability of the proposed method in correct estimation of mode shapes of the linear structures based on rather accurate modal frequencies.

• Transactions of the Korean Society of Mechanical Engineers
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• v.14 no.2
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• pp.298-309
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• 1990

In this paper, a new method is suggested to analyze impulsive stresses at loading poing of concentrated impact load under certain impact conditions determined by impact velocity, stiffness of plate and mass of impact body, etc. The impulsive stresses are analyzed by using the three dimensional dynamic theory of elasticity so as to analytically clarify the generation phenomenon of cone crack at the impact fracture of fragile materials (to be discussed if the second paper). The Lagrange's plate theory and Hertz's law of contact theory are used for the analysis of impact load, and the approximate equation of impact load is suggested to analyze the impulsive stresses at the impact point to decide the ranage of impact load factor. When impact load factors are over and under 0.263, approximate equations are suggested to be F(t)=Aexp(-Bt)sinCt and F(t)=Aexp(-bt) {1-exp(Ct)} respectively. Also, the inverse Laplace transformation is done by using the F.F.T.(fast fourier transform) algorithm. And in order to clarity the validity of stress analysis method, experiments on strain fluctuation at impact point are performed on a supported square glass plate. Finally, these analytical results are shown to be in close agreement with experimental results.

• The Journal of the Korea Contents Association
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• v.11 no.3
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• pp.449-459
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• 2011

This study was to explore the effect of local community on participation of local festival. In order to carry out the empirical study, 320 survey questionnaires were collected in Cheonan. AMOS 4.0 and SPSS Win 12.0 statistics packages were utilized for analysis of SEM. The study results were as follows: first, analysis on the relationship between identity and participation of local festival(interest of festival participation, extent of local festival, intention of local festival) Showed that identity effected every factor of participation of local festival, second, dependence effected interest of festival participation and intention of local festival, third, social friendship can't effected every factor of participation of local festival.

• Journal of Distribution Science
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• v.12 no.9
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• pp.73-82
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• 2014

Purpose - This study aims to illustrate the relationship between demographic factors and perceived risk types, supposing that Korean customers tend to postpone buying or hesitate to purchase the new version of hand sets, because of an early buying risk. Research design, data, and methodology - In addition to existing perceived risk types, the authors introduced an early buying risk. In order to measure each variable, also, the study has employed a five-point Liker-scale. To increase research reliability and validity, the research adopted an exploratory factor analysis, a confirmatory factor analysis, and one-way ANOVA. Results - First, there were statistically significant differences between financial risk and the group. Second, there weren't any statistically significant differences between the group means among the four perceived risk types (Performance Risk, Social Risk, Psychological Risk, and Physical Risk) and 4 factors (Gender, Age, Job, and Education). Lastly, job is apparently differentiated from others (Gender, Age, and Education). Conclusions - The authors found that customers regarded an early buying risk as one of the important perceived risk types, when purchasing a hand set.

• Journal of the Korea Safety Management & Science
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• v.13 no.4
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• pp.25-33
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• 2011

Workers in logistics centers also are exposed to serious musculoskeletal disorders the same as workers in general manufacturing due to operating forklifts and other labor duties. The frequency of these work related injuries decreases, workers' job satisfaction In addition, it causes many employees questioning a job change, which is regarded as the primary factor which drops the productivity. In this paper, we conducted a survey ti perceive the correlation between work related injuries in the fields of distribution centers and job satisfaction. Furthermore we made statistical analysis with our findings. The results of our analysis showed that the frequency of work related injuries due to workers' repetitive loading and unloading work is the primary factor which lowers job satisfaction. In order to improve aforementioned problem we propose first of all loading and unloading on pallet basis, second of all automation and computerization of logistics systems, and third of all ensurinf sufficient break time.

• Geomechanics and Engineering
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• v.35 no.2
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• pp.149-163
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• 2023

This paper presents stability evaluation of unlined tunnels with semi-circular arch and straight sides (SASS) driven in non-homogeneous and anisotropic undrained clay. Numerical analysis has been conducted based on lower bound finite element limit analysis with second order cone programming under plane strain condition. The solutions will be used for the assessment of stability of unlined semi-circular arch tunnels and tunnels in which semi-circular roof is supported over rectangular/square sections. The stability charts have been generated in terms of a non-dimensional factor considering linear variation in undrained anisotropic strength for normally consolidated and lightly over consolidated clay with depth, and constant undrained anisotropic strength for heavily over-consolidated clay across the depth. The effect of normalized surcharge pressure on ground surface, non-homogeneity and anisotropy of clay, tunnel cover to width ratio and height to width ratio of tunnel on the stability factor and associated zone of shear failure at yielding have been examined and discussed. The geometry of tunnel in terms of shape and size, and non-homogeneity and anisotropy in undrained strength of clay has been observed to influence significantly the stability of unlined SASS tunnels.

• Journal of Institute of Control, Robotics and Systems
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• v.9 no.6
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• pp.425-434
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• 2003

The disturbance observer(DOB) has been widely used in high speed and high precision motion control applications and the characteristics of DOB have been investigated in depth. Though most of DOB's have been implemented as the discrete-time form in digital devices, we are still short of the researches on discrete-time DOB (DDOB) in spite of rich references on continuous-time DOB. In this paper, we discuss about the disturbance rejection property and measurement noise effect of discrete-time DOB. Especially, we will focus on revealing the role of sampling time in designing the discrete-time DOB and show the validity of analysis through simulations and experiments for optical disk drive systems.