• 제목/요약/키워드: Se301

검색결과 81건 처리시간 0.021초

Sequential magnetic resonance spectroscopic changes in a patient with nonketotic hyperglycinemia

  • Shin, Ji-Hun;Ahn, So-Yoon;Shin, Jeong-Hee;Sung, Se-In;Jung, Ji-Mi;Kim, Jin-Kyu;Kim, Eun-Sun;Park, Hyung-Doo;Kim, Ji-Hye;Chang, Yun-Sil;Park, Won-Soon
    • Clinical and Experimental Pediatrics
    • /
    • 제55권8호
    • /
    • pp.301-305
    • /
    • 2012
  • Nonketotic hyperglycinemia (NKH) is a rare inborn error of amino acid metabolism. A defect in the glycine cleavage enzyme system results in highly elevated concentrations of glycine in the plasma, urine, cerebrospinal fluid, and brain, resulting in glycine-induced encephalopathy and neuropathy. The prevalence of NKH in Korea is very low, and no reports of surviving patients are available, given the scarcity and poor prognosis of this disease. In the current study, we present a patient with NKH diagnosed on the basis of clinical features, biochemical profiles, and genetic analysis. Magnetic resonance spectroscopy (MRS) allowed the measurement of absolute glycine concentrations in different parts of the brain that showed a significantly increased glycine peak, consolidating the diagnosis of NKH. In additional, serial MRS follow-up showed changes in the glycine/creatinine ratios in different parts of the brain. In conclusion, MRS is an effective, noninvasive diagnostic tool for NKH that can be used to distinguish this disease from other glycine metabolism disorders. It may also be useful for monitoring NKH treatment.

도심 환경에서 전파 특성 모의 해석을 위한 신호 독립 부트리 방법에 대한 연구 (Source Independent Subtree Ray Tracing Method for Wave Propagation Simulation in Urban Environment)

  • 권세웅;문현욱;오재림;윤영중
    • 한국전자파학회논문지
    • /
    • 제21권3호
    • /
    • pp.301-306
    • /
    • 2010
  • 본 논문에서는 도심과 같이 전기적으로 큰 환경에서 광선 추적법의 광선 추적을 통한 트리 구성 및 부트리 사용에 있어서 부트리 재사용을 통한 트리 생성 효율을 높이기 위해 신호원 독립 부트리 방법을 제안하였다. 신호원 독립 부트리 방법의 적용 결과, 피코셀 및 마이크로셀에서의 노드 개수가 트리 깊이 6에서 100배 감소하는 것을 확인하였으며, 노드 재사용 효율 분석을 통해 송신 위치가 변해도 전체 노드 중 88~98 %가 재사용되는 것을 확인하였다. 그러므로 제안된 신호원 독립 부트리 적용을 통해 광선 추적법 성능 개선은 물론 다중 안테나 또는 기지국 최적화와 같은 다중 송신기 사용 시 노드 재사용으로 인한 성능 개선에 유용하다.

이동최소제곱 다절점 유한요소를 이용한 새로운 전역-국부해석 (A New Global-Local Analysis Using MLS(Moving Least Square Variable-Node Finite Elements)

  • 임재혁;임세영
    • 한국전산구조공학회논문집
    • /
    • 제20권3호
    • /
    • pp.293-301
    • /
    • 2007
  • 본 연구에서는 이동최소제곱 다절점 유한요소를 이용한 새로운 전역-국부해석기법을 제시하였다. 다절점 유한요소는 요소의 변에 임의의 수 절점을 가질 수 있으므로, 여러 개의 유한요소를 요소망의 재구성 없이 동시적으로 결합시킬 수 있다. 이는 응력구배가 집중되는 곳에 유한요소망을 구성하는 데에 있어 큰 편의를 제공한다. 또한 기존의 전역-국부해석기법처럼 중첩된 요소망을 사용하거나, 지배방정식을 두 번 해석할 필요가 없기 때문에 매우 간편하고 정확하다. 제시된 방법론의 성능을 검증하기 위해 응력 집중과 관련된 다양한 다중스케일 문제를 해석하였다.

교직원의 공무상 요양급여제도 이용 현황 (The Utilization of Medical Care Benefits of School Personnel on Duty)

  • 이희우;신선미;김주자;강세원
    • 한국학교보건학회지
    • /
    • 제21권2호
    • /
    • pp.107-117
    • /
    • 2008
  • Purpose: To investigate the utilization of medical care benefits of school personnel on duty in Seoul. Method: The subjects were 551 workers under Seoul Metropolitan Office of Education(male 301, female 250) who got medical care benefits from March 2000 to February 2005. To analyze the data, frequency, chi-square test, and t-test by SAS package 9.12 were used. Result: The results show that elementary school personnel got the highest ranking, 314(57.0%). Among subjects, 57.2% personnel got accident when they were working on their own duty, 21% during school events and 13.5% were during commutes. They got medical care from orthopedics 75.9%, neurosurgery 7.6%, dental 4%, and 8 male and 2 female died during these days. The most frequent diseases of males and female were fracture and joints related disease. The reason of most health problem was due to injury(92.3%). Conclusion: The results of this study suggest that the continuous health care services like regular health check for school personnel, or social safety network to prevent injury are needed.

Multiplex PCR Detection of Waterborne Intestinal Protozoa: Microsporidia, Cyclospora, and Cryptosporidium

  • Lee, Seung-Hyun;Joung, Mi-Gyo;Yoon, Se-Joung;Choi, Kyoung-Jin;Park, Woo-Yoon;Yu, Jae-Ran
    • Parasites, Hosts and Diseases
    • /
    • 제48권4호
    • /
    • pp.297-301
    • /
    • 2010
  • Recently, emerging waterbome protozoa, such as microsporidia, Cyclospora, and Cryptosporidium, have become a challenge to human health worldwide. Rapid, simple, and economical detection methods for these major waterborne protozoa in environmental and clinical samples are necessary to control infection and improve public health. In the present study, we developed a multiplex PCR test that is able to detect all these 3 major waterborne protozoa at the same time. Detection limits of the multiplex PCR method ranged from $10^1$ to $10^2$ oocysts or spores. The primers for microsporidia or Cryptosporidium used in this study can detect both Enterocytozoon bieneusi and Encephalitozoon intestinalis, or both Cryptosporidium hominis and Cryptosporidium paNum, respectively. Restriction enzyme digestion of PCR products with BsaBI or BsiEI makes it possible to distinguish the 2 species of microsporidia or Cryptosporidium, respectively. This simple, rapid, and cost-effective multiplex PCR method will be useful for detecting outbreaks or sporadic cases of waterborne protozoa infections.

댄스스포츠 룸바 Forward Walk 시 숙련도에 따른 운동학적 특성 (Kinematic Character istics to Skill Degree during Dance Sports Rumba Forward Walk)

  • 서세미;김태삼
    • 한국운동역학회지
    • /
    • 제20권3호
    • /
    • pp.293-301
    • /
    • 2010
  • The purpose of this study was to investigate the kinematic difference between skilled and less skilled group for the forward walk at dance sports rumba. Six female players(skilled group: 3, less skilled group: 3) were participated as the subjects. To obtain the three-dimensional location coordinates in the joints and segments, it shot with 100Hz/s using 8 video cameras. Step length, shoulder rotation angle, orientation angle and angular velocity of pelvis were analyzed for each trail. The skilled group showed a bigger movement than the less skilled group at the shoulder rotation angle and ROM. The skilled group showed a bigger movement than the less skilled group at the up/down obliquity and internal/external rotation movement for pelvis. And the skilled group showed a bigger movement than the less skilled group at Maximum angle (down obliquity) of P2 and Maximum angle (up obliquity) of P3 to pelvis ROM. The skilled group showed a faster angular velocity than the less skilled group at P2 (+ direction, posterior) of anterior & posterior tilt, P2 & P3 (- direction, up) of up & down obliquity, and P2 (+ direction, external) of internal & external rotation.

FACTORS AFFECTING THE LACTATION LENGTH AND MILK YIELD IN NILI-RAVI BUFFALOES

  • Chaudhry, M.A.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제5권2호
    • /
    • pp.375-382
    • /
    • 1992
  • The effect of certain factors such as sex of calf, status of buffalo, season of calving, parity and sire on lactation length and total lactation yield was studied in 391 Nili-Ravi buffaloes. The average lactation length was $301.73{\pm}1.87$ (mean $\pm$ SE) days with a range of 181 to 505 days whereas the average lactation yield was $2031.08{\pm}19.16kg$ and ranged from 1023 to 6535 kg for 984 lactations. The differences in the means of lactation length and lactation yield due to the sex of calf were significant (p<0.05). The status of buffaloes had a significant (p<0.05) effect on lactation length but its effect on lactation yield was non-significant. The season of calving had no effect on lactation length but it influenced the lactation yield significantly. The milk yield was highest ($2150.81{\pm}43.52kg$) in buffaloes which calved in spring and lowest ($1959.92{\pm}30.83kg$) in autumn. The effect of parity on both traits under study was significant (p<0.01). The maximum and minimum lactation lengths of $309.82{\pm}3.96$ and $284.16{\pm}7.17$ days were observed in the first and sixth lactations, respectively. The milk yield was maximum ($2150.38{\pm}58.79kg$) in the seventh lactation and minimum (1818.31 60.04 kg) in the sixth lactation. The influence of sire was significant on lactation length (p<0.05) and milk yield (p<0.01).

가상현실을 이용한 중독치료 동향 분석을 위한 체계적 문헌고찰 (An Systematic Review of Trend Analysis in the Addiction Treatment Using Virtual Reality Technology)

  • 김진수;김나미;;장세은;박경은;김비
    • 한국콘텐츠학회:학술대회논문집
    • /
    • 한국콘텐츠학회 2017년도 춘계 종합학술대회 논문집
    • /
    • pp.301-302
    • /
    • 2017
  • 본 논문은 가상현실을 이용한 중독치료 동향분석을 위해 관련 연구사례들을 수집하고 중독현상별로 분류하여 치료방법과 치료의 유용성과 한계점, 발전 방안을 분석하였다. 학술연구 데이터베이스인 Science Direct, Medline, Proquest 그리고 Embase에 등재된 논문들 중 1999년부터 2016년까지 중독치료를 위해 가상현실 기술을 실험적으로 적용하고 효과를 검증한 연구 46편을 선정하여 중독의 범주별 치료효과를 분석하였다. 가상현실 치료내용은 단서노출치료를 주로 활용하고 있으며 연구대상은 청소년들보다 성인들이 더 많았다. 니코틴 중독 가상현실치료 연구가 가장 많은 수를 차지했고 그 다음으로는 알코올, 코카인/필로폰, 마리화나 순으로 확인되었다. 가상현실 치료는 다양한 중독 치료에 효과가 있었으며 인지치료와 함께 적용할 때 효과가 더 높았다. 치료의 한계점으로는 비용과 절차상 특수성, 사이버 멀미 등으로 인해 연구대상이 소수이며, 치료회기가 짧고, 장기연구 또는 추후연구를 실시한 경우 많지 않아 추후에 연구완성도를 보완하는 시도가 필요함을 알 수 있었다.

  • PDF

한국의료패널의 치과외래 이용 및 의료비 지출에 대한 4년간(2008-2011)의 변화추이 (Dental utilization and expenditures in Korea Health Panel Survey, 2008-2011)

  • 정세환
    • 대한치과의사협회지
    • /
    • 제52권5호
    • /
    • pp.291-301
    • /
    • 2014
  • Korea Health Panel Survey (KHPS) has been conducted to provide nationally representative estimates of health care use and expenditures for non-institutionalized population in Korea since 2008. The aim of this study was to present estimates from KHPS on dental utilization and expenditures from 2008 to 2011. While weighted estimates were presented for each year from 2008 to 2011, the focus of this study was on the 2011 estimates and changes in dental utilization and expenditures between 2008 and 2011. Weighted estimates were obtained using population weights and statistical significances were analysed by independent t-test or ANOVA test using SPSS version 20 for Windows. In 2011, 21.1% of Korean population obtained outpatient dental services from dentists. From 2008 to 2011, the percent of people with a dental visit in each year increased slightly. In 2011, the mean number of dental visits was 4.46. While the mean number of dental visits remained stable by 2010, it increased slightly in 2011. The total annual dental expense in 2011 for people with a visit was about 460,000 Korean Won and 10% higher in 2008. In summary, this study results highlight low rates of dental utilization and high dental expenses in Korean population.

Estimation of geometry-based manufacturing cost of complex offshore structures in early design stage

  • Nam, Jong-Ho;Sohn, Se-Hwan;Singer, David J.
    • International Journal of Naval Architecture and Ocean Engineering
    • /
    • 제4권3호
    • /
    • pp.291-301
    • /
    • 2012
  • A scalar metric for the assessment of hull surface producibility was known to be useful in estimating the complexity of a hull form of ships or large offshore structures by looking at their shape. However, it could not serve as a comprehensive measuring tool due to its lack of important components of the hull form such as longitudinals, stiffeners, and web frames attached to the hull surface. To have a complete metric for cost estimation, these structural members must be included. In this paper, major inner structural members are considered by measuring the complexity of their geometric shape. The final scalar metric thus consists of the classes containing inner members with various curvature magnitudes as well as the classes containing curved plates with single and double curvature distribution. Those two distinct metrics are merged into a complete scalar metric that accounts for the total cost estimation of complex structural bodies.