• Journal of Oral Medicine and Pain
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• 제19권2호
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• pp.153-168
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• 1994

The aim of the present study was to investigate a relation between occlusal wear area and occlusal contact patterns. For the purpose, occlusal wear area were measured in 58 dental students and in 129 patients with temporomandibular disorders(TMDs) from dental casts. Teeth used in this study were from canine to second molar on both sides in upper arch, totally ten. Occlusal wear area on casts was marked by pencil and photocopies, and then, the area was measured with planimeter. Occlusal relation was clinically examined with regard to Angle's classification, chewing side preference, lateral guidance pattern and bruxing and/or clenching habit. T-Scan, electronic occlusal contact analyzer, was used to record occlusal contact number, contact force, contact time and occlusal balance that is TLR(total left-right statistics) during tooth contact. All measurement were repeated 3 times and the average value was used for data processing. The obtained results were as follows : 1. Mean value of occlusal wear area did not differ significantly between dental students and patients. 2. There ws not significant difference in wear area between chewing side and non-chewing side in both groups. 3. Occlusal wear area was significantly increased with age in both groups. 4. Three subgroups divided by Angle's classification did not show any difference in occlusal wear area among them, but three subgroups divided by lateral guidance pattern showed slightly significant difference between canine guide subgroup and group function subgroup in patients. Occlusal wear ares\a in group function subgroup wear larger than canine guide subgroup. 5. Mean value of wear area in patients with bruxing and/or clenching habit did not differ from those in patients without such habit. 6. Correlationship among items related to occlusal contact pattern were highly consistent and significant in dental students and only one item significantly correlated with occlusal wear area was tooth contact time.

• 한국환경성돌연변이발암원학회지
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• 제16권1호
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• pp.13-18
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• 1996

One mechanism of free-radical production by ethanol is suggested to be through the intracellular conversion of XDH to XO by increased ratio of NADH to NAD. The major mechanism for physiological compensation of cytosolic NADH/NAD balance is the malate/aspartate shutfie. Therefore, it is important to develop the method to improve the efficiency of malate/aspartate shuttle in ethanol metabolism. In the present study, various amino acids and organic acid involved in the shuttle were tested for their functional efficiency in modulating shuttle in the ethanol-perfused rat liver. The rate of ethanol oxidation in the liver perfused with aspartate alone or aspartate in combination with pyruvate, respectively, was increased by about 10% compared to control liver, but not in the tissues perfused with glummate, cysteine or pyruvate alone. Though glummate, cysteine and pyravate did not affect the ethanol oxidation significanfiy, they showed some suppresive effect on the ethanol-induced radical generation monitored by protein carbonylation analysis. Among the tested components, aspartate is confirmed to be the most efficient as a metabolic regulator for both ethanol oxidation and ethanol-induced oxidative stress in our perfusion system. These effects of aspartate would result from NAD recycling by its supplementation through the coupled aspartate aminotransferase/malate dehydrogenase reactions and the malate-aspartate shuttle.

• 대한기계학회논문집B
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• 제28권1호
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• pp.24-30
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• 2004

Analysis model for the two-phase catalytic reactor is presented. With the progress in development of micro thermofluidic devices, needs fur understanding of the phenomena in two phase reaction in cm scale has been arisen. To investigate thermal and reactive performance of down scaled two phase reactor simple analysis model that is a kind of lumped flow model is proposed. Analysis model presented is based on the experiment on mm scale model reactor. Target experiment is catalytic decomposition of 70wt％ hydrogen peroxide with existence of perovskite L $a_{0.8}$S $r_{0.2}$Co $O_3$ catalyst. It is composed of balance equations of mass and energy. Each phase is considered to be a species fur the simplicity. Axial diffusion and transversal distribution of properties are neglected. Two phase catalytic reaction is modeled as successive gasification of liquid lump around catalyst and reaction in gas phase. Heat transfer is modeled by model function ofNu number. Modeled Nu is expressed as Nu=N $u_{0}$ (1＋ $a_1$( $a_2$ $T^{-}$ $a_3$)exp( $a_4$ $T^{-1}$)exp( $a_{5}$ z). Transfer coefficients are determined by the comparison of experimental results. With the model, heat transfer characteristics are investigated. Also by the mass transfer coefficient, characteristics in mass transfer is investigated. With the result basic understanding on design and analysis of mm scale two-phase reactive device is obtained. Also it can be further applied to micro scale reactive device fabricated by micromachining.ing..

• 한국식품영양학회지
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• 제27권5호
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• pp.760-770
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• 2014

The purpose of this study was to measure the nutrition knowledge, dietary attitude, eating behavior, physical ability and locomotion of 5-year-old-children, and thereby to provide the fundamental information necessary to develop a nutritionrelated physical education program. A survey was performed on 143 5-years-old boys and 113 girls. The results were as follows. The average score in the nutrition knowledge item, was 7.22 out of a possible 10 points; in the dietary attitude item, 32.46 out of 50 points; in the eating behavior item, 26.67 out of 40 points. According to body measurement, there was a significant difference in height by gender (p<0.05), Significant differences in muscle mass and basal metabolic rate were also observed by gender (p<0.001). Gender also influenced the flexibility and reflexibility (p<0.001), with significant difference in balance of the right side (p<0.01). Although this study was limited by its cross-sectional study design, the body muscle (p<0.05) and basal metabolic rate (p<0.05) were observed to have a positive relation with nutritional knowledge. In addition, there was a significant positive correlation between nutritional knowledge and dietary attitude (p<0.01). According to the results, it is necessary to develop a long-term and systematic program with the combination of nutrition and physical education to develop correct dietary habits and for the balanced growth of children.

• The Journal of Korean Physical Therapy
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• 제19권1호
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• pp.11-22
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• 2007

Purpose: The purpose of this study were to analysis the effect on change of spinal neuron excitability during gait training of hemiplegia patients by the functional electrical stimulation. Methods: Thirty six hemiplegia patients participated in this study. Stimulation conditions of FES were pulse rate 35pps, pulse width $250{\mu}s$, and on-time 0.3 second, treatment hour was 30 min. and treatment period was once a day for five days a week through six weeks. For functional evaluations before and after treatment, Modified Ashworth Scale (MAS), active range of motion (AROM), Hmax threshold, H/Mmax ratio were measured and the following conclusions were obtained. Results: Functional evaluation showed significant changes in experimental group as MAS(p<0.01), AROM(p<0.001), compared to control group. In spinal neuron excitability evaluation, change of Hmax threshold was significantly reduced in both non weight bearing (p<0.001) and bearing condition (p<0.05), H/Mmax ratio was significantly reduced in non weight bearing (p<0.05) and bearing condition (p<0.05). Conclusion: In conclusion, application of FES to hemiplegia patients in recovery stage during gait training improved mitigation of muscular spasticity, balance adjustment and moving ability and it was interpreted that it was caused by mitigation of muscular spasticity by the spinal neuron excitability.

• 동의생리병리학회지
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• 제24권6호
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• pp.1142-1148
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• 2010

This case study was reported to show the effects of Seongnoe-gaegyubeop acupuncture treatment. The methods were applied to patients who had the sequela of cerebral vescular accident(CVA) and had no progression for 3~6 months after the onset of CVA. The patients had no progression in spite of receiving medical treatment for 3~6 months after the onset of CVA. The patients were treated with Seongnoe-gaegyubeop acupuncture treatment. The patient's standing, sitting state and activities of daily life like dressing, feeding etc were assessed by Berg balance scale, Barthel Index and Manual Muscle Testing. After 3 months of this treatment, the standing, sitting state and activities of daily life were improved. I think that acupuncture treatment of Seongnoe-gaegyubeop is effective treatment method to treat the patient who caused the sequela of CVA.

• 한국물환경학회지
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• 제30권5호
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• pp.491-502
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• 2014

As meteorology is the driving force for lake thermodynamics and mixing processes, the effects of climate change on the physical limnology and associated ecosystem are emerging issues. The potential impacts of climate change on the physical features of a reservoir include the heat budget and thermodynamic balance across the air-water interface, formation and stability of the thermal stratification, and the timing of turn over. In addition, the changed physical processes may result in alteration of materials and energy flow because the biogeochemical processes of a stratified waterbody is strongly associated with the thermal stability. In this study, a novel modeling framework that consists of an artificial neural network (ANN), a watershed model (SWAT), a reservoir operation model(HEC-ResSim) and a hydrodynamic and water quality model (CE-QUAL-W2) is developed for projecting the effects of climate change on the reservoir water temperature and thermal stability. The results showed that increasing air temperature will cause higher epilimnion temperatures, earlier and more persistent thermal stratification, and increased thermal stability in the future. The Schmidt stability index used to evaluate the stratification strength showed tendency to increase, implying that the climate change may have considerable impacts on the water quality and ecosystem through changing the vertical mixing characteristics of the reservoir.

• 대한지리학회지
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• 제42권3호
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• pp.315-331
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• 2007

한국 불교 사찰을 대표하는 불국사는 활단층인 불국사(울산)단층선이 통과하는 한반도에서 지반이 가장 불안정한 곳에 입지 한다. 사찰이 조성된 선상지 지형면의 폭이 좁고 경사가 급하므로 건축자들은 불교의 상징세계를 완성하기 위하여 부지의 남쪽과 서쪽을 확장하였다. 인위적으로 넓힌 공간에는 이 지역의 지형적 특성을 고려하여 내진 구조를 고안하여 적용하였다. 건축미를 극대화하면서 중요한 목적인 내진 기능을 작동시키기 위하여 화강암을 목재처럼 가공하거나 자연석과 다듬은 석재를 이용하여 여러 장치들을 고안하였다. 불국사에 적용된 내진 구조는 그렝이법, 목조건축 기법을 적용한 석조구조(결구), 주두석(동틀돌, 첨차석)의 이용, 유공초석의 사용이다. 석축을 구성하고 있는 각 부분들은 나름대로 지진에너지를 흡수하는 특별한 역할을 하면서 전체적으로 균형과 조화를 이루고 있다. 복잡하고 세밀한 내진 구조들을 겉으로 드러내지 않고 석축 안에 감추면서 미학적으로 절정의 건축물을 만든 건축설계는 1250년 전 신라인들의 기술 수준을 짐작하게 한다. 기교에만 치우쳐 지나치게 치장한 것으로도 보일 수 있는 이 건축물의 진정한 미는 과학에 근거한 아름다움을 추구한 것이다.

• 한국운동역학회지
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• 제19권2호
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• pp.245-255
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• 2009

본 연구는 낙상을 경험한 여성노인 20명을 각각 10명씩 연령으로 집단을 구분하고 보행 시 하지관절의 협응 능력을 분석하여 운동과학적인 기초자료를 제시하고, 불안정적인 측면의 요소에 효과적으로 대처할 수 있도록 하기 위한 것이다. 이를 위해 보행 시 하지관절의 균형에 대한 기전과 차이를 동작분석과 근전도를 이용하여 비교 분석하여 다음과 같은 결론을 얻었다. 첫째, 보행 시 고관절의 움직임에서 연령증가로 인해 충분하지 못한 지지역할로 보행자세가 저하되어 안정적 이지 못한 패턴을 보였다. 둘째, 무릎관절의 움직임에서 좌우측의 보행패턴이 상이하게 이루어지는 경향을 나타내었다. 셋째, 발목관절의 움직임에서 연령증가와 함께 활보패턴이 비정상적인 경향을 나타내었다. 또한 보행 시 하지 주요근육의 활성정도에 대해 대퇴직근과 대퇴이두근은 무릎의 굴곡을 막기 위해 근수축 활성이 증가되어 전진하는 전기적 특성을 보였고, 전경골근과 내측비복근은 이동 시 높은 전기적 수요를 나타내어 저측굴곡의 비율을 줄여 보행하는 특성을 나타내었다.

• Journal of Microbiology and Biotechnology
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• 제30권11호
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• pp.1640-1650
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• 2020

Colorectal cancer (CRC) is the leading cause of common malignant neoplasm worldwide. Many studies have analyzed compositions of gut microbiota associated with various diseases such as inflammatory bowel diseases (IBD) and colon cancer. One of the most representative bacteria involved in CRC is enterotoxigenic Bacteroides fragilis (ETBF), a species belonging to phylum Bacteroidetes. We used ETBF colonized mice with azoxymethane (AOM)/dextran sulphate sodium (DSS) and zerumbone, a compound with anti-bacterial effect, to determine whether zerumbone could restore intestinal microbiota composition. Four experimental groups of mice were used: sham, ETBF colonized AOM/DSS group, ETBF colonized AOM/DSS group zerumbone 60 mg kg-1 (ETBF/AOM/DSS + Z (60)), and only zerumbone (60 mg kg^-1)-treated group. We performed reversible dye terminators-based analysis of 16S rRNA gene region V3-V4 for group comparison. Microbiota compositions of ETBF/AOM/DSS + Z (60) group and ETBF colonized AOM/DSS group not given zerumbone were significantly different. There were more Bacteroides in ETBF/AOM/DSS + Z (60) group than those in ETBF colonized AOM/DSS group, suggesting that B. fragilis could be a normal flora activated by zerumbone. In addition, based on linear discriminant analysis of effect size (LEfSe) analysis, microbial diversity decreased significantly in the ETBF colonized AOM/DSS group. However, after given zerumbone, the taxonomic relative abundance was increased. These findings suggest that zerumbone not only influenced the microbial diversity and richness, but also could be helpful for enhancing the balance of gut microbial composition. In this work, we demonstrate that zerumbone could restore the composition of intestinal microbiota.