• Journal of Genetic Medicine
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• v.11 no.2
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• pp.43-48
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• 2014

Chorionic villus sampling has gained importance as a tool for early cytogenetic diagnosis with a shift toward first trimester screening. First trimester screening using nuchal translucency and biomarkers is effective for screening. Chorionic villus sampling generally is performed at 10-12 weeks by either the transcervical or transabdominal approach. There are two methods of analysis; the direct method and the culture method. While the direct method may prevent maternal cell contamination, the culture method may be more representative of the true fetal karyotype. There is a concern for mosaicism which occurs in approximately 1% of cases, and mosaic results require genetic counseling and follow-up amniocentesis or fetal blood sampling. In terms of complications, procedure-related pregnancy loss rates may be the same as those for amniocentesis when undertaken in experienced centers. When the procedure is performed after 9 weeks gestation, the risk of limb reduction is not greater than the risk in the general population. At present, chorionic villus sampling is the gold standard method for early fetal karyotyping; however, we anticipate that improvements in noninvasive prenatal testing methods, such as cell free fetal DNA testing, will reduce the need for invasive procedures in the near future.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1996.04a
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• pp.10-10
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• 1996

• Research in Community and Public Health Nursing
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• v.4 no.1
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• pp.25-37
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• 1993

This study was designed to identify the performance of occupational health services of 37 industries located in Kyung in area. The data was collected by a structured questionnaire developed by the Academic society of Community Nursing. This analysis had two factors, one was related to six of the industries, and the other was the actual assignment procedures of the health team members. This study was undertaken from December 4, 1992 to January 21, 1993. The results of the study were as follows: 1. The study group was primarily manufacturing industries which employed 300-1,000 employees. 2. The actual assignment state of occupation health team members with the exception of nurses was not kept to the regulations of the industrial safety health law. 3. The following was the analysis of the performance of occupational health services with two factors: 1). The larger the size of the six industries, the more the performance of health education, health assessment, and health screening. 2) The actual. practice of occupational health team members working environmental measurement, was more frequently performed by a nurse other than health team members together. 4. 1) The subscription rate of the laborers for primary health screening was 94%, and of these 10% had the need of secondary health screening. As a results of the secondary health screening the degrees were 'A' 45%, 'C' 92%, 'R' 21%. Of these degrees 'C', 'R' 4% were follow up cases. 2) 43% of laborers needed special health screening and .of these the subscription rate was 99%. The main item of the special health screening was physical factors. After the special health screening 46% required .follow up, 30% required medical treatment, only reporting 18%, change work 8%, suspension from work place 2%.

• Korean Journal Plant Pathology
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• v.14 no.4
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• pp.339-344
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• 1998

Since the leaf inoculation procedures are time-consuming and require considerable growth chamber space, a rapid dioassay method for screening of pathogenicity of Didymella bryoniae, a casual agent of gummy stem blight in watermelon, was established in this paper. The method produced reliable results within 8 days ( 5 days for growing seedlings and 3 days for rapid disease response in the seedlings). After contaminants in the root of 4~5 day-old seedlings had been washed using sterilized water, 5 seedlings were dipped into a vial containing 12 ml of conidial suspension (106 cells/ml). After the vials were placed in a growth chamber (22$^{\circ}C$, RH 50%, 14hr light/10hr darkness) for 3 days, susceptibility and resistance of cultivars were determined by the degree of disease response on cotyledon. The result of obtained by the dip-inoculation method was well coincided with the results by the leaf inoculation procedures and the result that had been observed for several years in the field. Screening of collected watermelon cultivars by the dip-inoculation method revealed that all the 21 domestic cultivars collected were susceptible and only 3 foreign cultivars (PI 189225, PI 482322 and IT 188207) were resistant among 18 cultivars A cucumber cultivar (Marketer) and bitter cucumber were proven to be resistant against the D. bryoniae among 8 other different cucurbits tested. The SDS-PAGE patterns of total proteins from a susceptible (Keumcheon) and a resistant (PI 189225) watermelon cultivars were compared 0, 12, 24 and 36 hrs after inoculation. The amounts of two distinct protein bands (24 kDa and 70 kDa) were gradually increased after inoculation in both cultivars.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.975-981
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• 2014

Cervical cancer is an issue of foremost importance globally, specifically affecting the developing nations. Significant advances have taken place with regard to diagnosis of cervical cancer, especially with screening. Appropriate screening measures can thus reduce the incidence of cervical cancer. The most desirable screening technique should be less invasive, easy to perform, cost-effective and cover a wide range of diagnostic icons. Manual liquid based cytology (MLBC) can be considered as one of the suitable technique for screening with the above-mentioned benefits. The aim of the current study was to compare two cervical screening techniques on the basis of different morphological parameters and staining parameters by using modified acetic acid Pap staining to see the possibility of reducing time economy involved in conventional Pap staining (CPS). The study was conducted on a total 88 cases and all were analyzed with both MLBC and CPS. Forty eight cases that were regarded as satisfactory on the basis of Bethesda system by both methods were further recruited for investigation. Their morphological parameters and staining quality were compared and scored according to a scoring system defined in the study. Quality indices was calculated for both staining procedures and smear techniques.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5523-5528
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• 2014

Objective: To evaluate the implementation of screening colonoscopy amongst first-degree relatives (FDRs) of patients with colorectal cancer (CRC) in Turkey. Materials and Methods: A total of 400 first-degree relatives (mean(SD)age: 42.5(12.7) years, 55.5% were male) of 136 CRC patients were included in this cross-sectional questionnaire based survey. Data on demographic characteristics, relationship to patient and family history for malignancy other than the index case were evaluated in the FDRs of patients as were the data on knowledge about and characteristics related to the implementation of screening colonoscopy using a standardized questionnaire form. Results: The mean(SD) age at diagnosis of CRC in the index patients was 60.0(14.0) years, while mean(SD) age of first degree relatives was 42.5(12.7) years. Overall 36.3% of relatives were determined to have knowledge about colonoscopy. Physicians (66.9%) were the major source of information. Screening colonoscopy was recommended to 19.5% (n=78) of patient relatives, while 48.7% (n=38) of individuals participated in colonoscopy procedures, mostly (57.9%) one year after the index diagnosis. Screening colonoscopy revealed normal findings in 25 of 38 (65.8%) cases, while precancerous lesions were detected in 26.3% of screened individuals. In 19.0% of FDRs of patients, there was a detected risk for Lynch syndrome related cancer. Conclusions: In conclusion, our findings revealed that less than 20% of FDRs of patients had received a screening colonoscopy recommendation; only 48.7% participated in the procedure with detection of precancerous lesions in 26.3%. Rise of awareness about screening colonoscopy amongst patients with CRC and first degree relatives of patients and motivation of physicians for targeted screening would improve the participation rate in screening colonoscopy by FDRs of patients with CRC in Turkey.

• Proceedings of the ESK Conference
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• 1995.10a
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• pp.56-61
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• 1995

Multimedia systems present information by using various media, for example, video, sound, music, animation, movie, etc., in addition to the text which has long been used for conveying the information. Among many multimedia applications, the multimedia information retrieval systems commercialized in the form of multimedia encyclopedia CD-ROMs, benefit by using various media for their ability to present information in an efficient and complete way. But using various media may cause end users' confusion and furthermore, poor user-interface design often exacerbates the systems. For appropriate design of the user interface of multimedia information retrieval systems, we investigated the characteristics of the multimedia information retrieval systems and listed 35 variables that might affect the usability of the user interface. And we selected 10 variables through some procedures such as brainstorming, literature survey, expert opinion, relevance analysis and feasibility analysis, in order to perform a screening study which will remarkably reduce the cost and time in conducting subsequent human factors experiments.

• Journal of Mechanical Science and Technology
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• v.18 no.6
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• pp.1010-1018
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• 2004

This study presents the methodological aspects of combustion instability modeling and provides the numerical results of the model (sub-scale) combustion chamber, regarding geometrical dimensions and operating conditions, which are for determining the combustion stability boundaries using the model chamber. An approach to determine the stability limits and acoustic characteristics of injectors is described intensively. Procedures for extrapolation of the model operating parameters to the actual conditions are presented, which allow the hot-fire test data to be presented by parameters of the combustion chamber pressure and mixture (oxidizer/fuel) ratio, which are customary for designers. Tests with the model chamber, based on the suggested scaling method, are far more cost-effective than with the actual (full-scale) chamber and useful for injector screening at the initial stage of the combustor development in a viewpoint of combustion instabilities.

• Proceedings of the Korea Concrete Institute Conference
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• 2009.05a
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• pp.467-468
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• 2009

In this study, seismic capacity of R/C school buildings are investigated on the basis of the 2nd and 3rd level procedures of the Japanese Standard for Evaluation of Seismic Capacity of Existing R/C Buildings, push-over analysis and nonlinear dynamic analysis, respectively. In order to verify the applicability of the new method proposed in this study, relationships between evaluation results of the proposed methods shown in Part-2 and detailed evaluation methods mentioned above are compared.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2000.06a
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• pp.1900-1906
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• 2000

In this study, the vibration screening effectiveness of barriers which can isolate structures from ground-transmitted vibration generated by harmonic forces is performed. For high frequencies, the vibration screening effectiveness of barriers is analyzed from field tests, and compared with the results from numerical analyses using a commercial program, ANSYS. Using these numerical analysis procedures, the effectiveness for vibration with various low frequencies is predicted. The frequency analysis tests of surface waves are performed in order to estimate the dynamic material properties of soil for 100 Hz, 150 Hz, 200 Hz, and 250 Hz. Three-dimensional solid elements are used in order to consider the diffraction of waves in all directions. Spring-damper combination elements are used in order to avoid the reflection of waves on the boundary. The results of numerical analysis agree with those of field tests. From the results of this numerical analyses, the reduction of vibration for low frequencies induced by the traffic loads can be predicted.