• Title/Summary/Keyword: Screening Methodology

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Seismic Capacity Evaluation of Low-Rise Reinforced Concrete Buildings in Korea (국내 저층 철근콘크리트 건물의 내진성능 평가)

  • Lee, Kang-Seok;Kim, Yong-In;Min, Kyung-Min
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.11a
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    • pp.241-244
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    • 2008
  • The authors proposed a new rapid-screening method for more reasonably evaluating seismic capacities of medium and low-rise RC buildings controlled by both shear and flexure in Ref. [1]. The method proposed in Ref. [1] was based on relationships between required strengths of each failure system for ductility factors and damage degrees of overall system derived from the view-point of ductility factors. The proposed method was also verified using observed real damage data of low-rise RC buildings caused by past earthquakes. Results indicated that the methodology proposed in Ref. [1] compares well with real damages and is a useful strategy for rapidly identifying low-rise RC buildings having high potential seismic risk. In this study, in order to verify the applicability of the new methodology proposed in Ref. [1] to real RC building systems, seismic capacities of existing eleven low-rise RC buildings in Korea are evaluated based on the new method.

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Enhanced Production of Cellulase-Free Thermoactive Xylanase Using Corncob by a Black Yeast, Aureobasidium pullulans CBS 135684

  • Bankeeree, Wichanee;Lotrakul, Pongtharin;Prasongsuk, Sehanat;Kim, Seung Wook;Punnapayak, Hunsa
    • Korean Chemical Engineering Research
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    • v.54 no.6
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    • pp.822-829
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    • 2016
  • Our aim was to optimize the production of cellulase-free thermoactive xylanase by Aureobasidium pullulans CBS 135684 with statistical methodology based on experimental designs. Among eleven variables, the nutrient sources that had significant effect on xylanase production were corncob, $(NH_4)_2SO_4$, xylose, $KH_2PO_4$ and tween 80, identified by the initial screening method of Plackett-Burman. The optimum concentrations of these five components were subsequently investigated using response surface methodology. The optimal concentrations ($g{\cdot}l^{-1}$) for maximum production of xylanase were corncob, 39.0; $(NH_4)_2SO_4$, 3.0; xylose, 1.8; $KH_2PO_4$ 1.4; and tween 80, 1.4, respectively. An improved xylanase yield of $8.74{\pm}0.84U{\cdot}ml^{-1}$ was obtained with optimized medium which is 2.1-fold higher production than previously obtained results ($4.10{\pm}0.10U{\cdot}ml^{-1}$) after 48 h of cultivation. In addition, the xylanase production under optimal condition reached $10.09{\pm}0.27U{\cdot}ml^{-1}$ after 72 h of cultivation.

An Application-embedded method to trace OTT viewing patterns on smartphone (스마트폰에서의 OTT(Over The Top)서비스 시청패턴 추적 어플리케이션 설계 : 티빙(tving)을 중심으로)

  • Choi, Sun-Young;Kim, Min-Soo;Kim, Myoung-Jun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.4
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    • pp.1000-1006
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    • 2014
  • This study focuses on the fact that a OTT service is vigorously used for smart phones, and suggests a design of method to trace the experiences of watching television contents. For this purpose, we developed logging functions and embedded them into existing OTT service application to record flow and pattern of watching context. This paper suggests a log file format which can accurately and precisely record watching actions of users per-second methodology rather than former per-minute methodology. Moreover, this study shows that the application can trace watching attitude according to occurring events by characteristics and playing modes of realtime broadcasting, VOD, advertisement contents. In addition, based on the result of the study, this paper discusses educational, operational meaning of the method such as methodological application in mobile ethnography field or survey for total screening rate.

Methodology of Springback Prediction of Automotive Parts Applied 3rd Generation AHSS Using the Progressive Meta Model (프로그레시브 메타모델을 이용한 3세대 초고장력강판 적용 차체 부품의 스프링백 예측 방법론)

  • Yoon, J.I.;Oh, K.H.;Lee, S.R.;Yoo, J.H.;Kim, T.J.
    • Transactions of Materials Processing
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    • v.29 no.5
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    • pp.241-250
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    • 2020
  • In this study, the methodology of the springback prediction of automotive parts applied 3rd generation AHSS was investigated using the response surface model analysis based on a regression model, and the meta model analysis based on a Kriging model. To design the learning data set for constructing the springback prediction models, and the experimental design was conducted at three levels for each processing variable using the definitive screening designs method. The hat-shaped member, which is the basic shape of the member parts, was selected and the springback values were measured for each processing type and processing variable using the finite element analysis. When the nonlinearity of the variables is small during the hat-shaped member forming, the response surface model and the meta model can provide the same processing parameter. However, the accuracy of the springback prediction of the meta model is better than the response surface model. Even in the case of the simple shape parts forming, the springback prediction accuracy of the meta model is better than that of the response surface model, when more variables are considered and the nonlinearity effect of the variables is large. The efficient global optimization algorithm-based Kriging is appropriate in resolving the high computational complexity optimization problems such as developing automotive parts.

Proposal for the list of potential radionuclides of interest during NPP site characterization or final status surveys

  • Seo, Hyung-Woo;Oh, Jae Yong;Shin, Weon Gyu
    • Nuclear Engineering and Technology
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    • v.53 no.1
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    • pp.234-243
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    • 2021
  • In the research or project planning for the decommissioning of a nuclear power plant, one of several preparations will be the establishment of a list of potential radionuclides to be considered at the time of characterization or final status surveys. Reliable data for selection of potential radionuclides during the transition period to prepare for decommissioning will depend heavily on historical data at the site or, where possible, sampling analysis. However, during the transition period, direct sampling can be challenging, depending on the circumstances of the site or national regulation. A methodology of selecting potential radionuclides for nuclear facility sites which largely consists of three major processes: production of initial list of radionuclides, selection of the insignificant radionuclide that will be eliminated, and consideration of site characterization or sampling. For developing a preliminary list of potential radionuclides for Kori Unit 1 decommissioning, the list of initial radionuclides was made referring to the technical documents applied at decommissioned NPPs in the U.S and additional reference materials applied until the operation of NPPs in Korea. For the screening of insignificant radionuclides, we applied criterion of less than 0.1% of the amount of radioactivity inventory and confirmed the dose fraction using the RESRAD code. The final suit of radionuclides was established, which should be supplemented by reflecting site characterization and sampling process in the future. Thus, the methodology and results for the selection of potential radionuclides suggested in this paper can give an insight as a future reference to deriving DCGLs in relation to site remediation of decommissioning nuclear plants.

A Case Study of Expanding the Health Impact Assessment on the Residential Development Projects (주거지 개발계획에 대한 건강영향평가 확대와 사례분석)

  • Kim, Eunchae;Ha, Jongsik;Tak, Jongseok
    • Journal of Environmental Impact Assessment
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    • v.31 no.4
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    • pp.250-264
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    • 2022
  • The development projects subject to health impact assessment (HIA) in the current environmental impact assessment (EIA) system are limited to some projects under Article 12 of the Enforcement Decree of the Environmental Health Act (Additional Assessment Objects Subject to Health Impact Assessment Items), but health impact-related matters are being evaluated and reviewed during consultation. In particular, when a development site is planned around some pollutant sources in a residential development plan, it is evaluated and reviewed whether the site meets the risk criteria through a current concentration survey of major hazardous air pollutants. This study prepared a quantitative method to confirm the validity of the location of the residential area to be developed in the residential development plan and proposed a plan to expand the project subject to HIA within the EIA procedure. A detailed methodology was proposed by reviewing the screening and scoping procedures of the EIA system, and a case analysis of the urban development plan discussed in the past was conducted to verify the methodology.

Robust ridge regression for nonlinear mixed effects models with applications to quantitative high throughput screening assay data (비선형 혼합효과모형에서의 로버스트 능형회귀 방법과 정량적 고속 대량 스크리닝 자료에의 응용)

  • Yoo, Jiseon;Lim, Changwon
    • The Korean Journal of Applied Statistics
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    • v.31 no.1
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    • pp.123-137
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    • 2018
  • A nonlinear mixed effects model is mainly used to analyze repeated measurement data in various fields. A nonlinear mixed effects model consists of two stages: the first-stage individual-level model considers intra-individual variation and the second-stage population model considers inter-individual variation. The individual-level model, which is the first stage of the nonlinear mixed effects model, estimates the parameters of the nonlinear regression model. It is the same as the general nonlinear regression model, and usually estimates parameters using the least squares estimation method. However, the least squares estimation method may have a problem that the estimated value of the parameters and standard errors become extremely large if the assumed nonlinear function is not explicitly revealed by the data. In this paper, a new estimation method is proposed to solve this problem by introducing the ridge regression method recently proposed in the nonlinear regression model into the first-stage individual-level model of the nonlinear mixed effects model. The performance of the proposed estimator is compared with the performance with the standard estimator through a simulation study. The proposed methodology is also illustrated using quantitative high throughput screening data obtained from the US National Toxicology Program.

Construction of a Focused Library of 2-benzylimino-1,3-thiazolines and Their Fungicidal Activities (2-벤질이미노-1,3-티아졸린 유도체의 집중 라이브러리의 구축 및 이들의 살균활성)

  • Park, Ik-Kyu;Lim, Chul-Soo;Nam, Kee-Dal;Shin, Dong-Yoon;Choi, Kyung-Ja;Cho, Kwang-Yun;Hahn, Hoh-Gyu
    • The Korean Journal of Pesticide Science
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    • v.10 no.2
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    • pp.149-152
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    • 2006
  • Construction of focused library of 2-benzylimino-1,3-thiazolines 7 through molecular modification of 3-alkyl-2-phenylimino-1,3-thiazolines 1 which showed selective fungicidal activity against rice blast and their fungitoxic activity against 6 kinds of typical plant diseases was described. Fifty four compounds of focused library of 2-benzylimino-1,3-thiazolines 7 were synthesized from the reaction of the corresponding $\gamma$-chloroacetoacetanilides 6 with N-benzyl thioureas 5 by parallel synthetic methodology. As results of fungicidal screening against the typical plant diseases, twenty eight kinds of 7 at 100 ${\mu}g$ $mL^{-1}$ showed the control value over 50% against tomato late blight.

Development of Sensible Brassiere for Middle Aged Women -Investigation of consumer's Needs and Evaluation of Commercial Brassiere for the Development of Subjective Measurement Scale and Screening of Design Parameters- (중년 여성의 감성 Brassiere 개발(제1보) -소비자 요구 분석을 기초로 한 제품 디자인 요소 추출-)

  • 김정화;이선영;홍경희
    • Journal of the Korean Society of Clothing and Textiles
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    • v.24 no.5
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    • pp.714-723
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    • 2000
  • The purpose of this study is to develop functional and sensible brassiere for middle-aged women. As a methodology, engineering design process, especially, QFD(Quality Function Deployment) was adopted to translate consumer's needs into product design parameters. Wearing tests of commercial brassiere were performed for the development o subjective measurement scale. The environmental condition was controlled at 28$\pm$1$^{\circ}C$, 65$\pm$3%RH. As results, subjective measurement scale and dimension for the evaluation of sensible brassiere were extracted from factor analysis. Four factors were fitting, aesthetic property, pressure sensation, displacement of brassiere due to movement. Regression equations with the subjective evaluation descriptors were developed for the prediction of wearing comfort of brassiere. (R2=.82) The most critical design parameter was wire-related property and second one was stretchability of main material of brassiere. Also, wearing comfort of brassiere was affected by the interaction of initial stretchability of wing and support of strap.

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Effects of Tobacco Smoking on the Dorsum of the Tongue and Buccal Epithelium

  • Al Shammari, Abdullah Faraj;AL Ibrahim, Ibrahim Khalil;Alaauldeen, Amjad Ibrahim;Merza, Randa Fouad;Ahmed, Hussain Gadelkarim
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.10
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    • pp.4713-4718
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    • 2016
  • Objective: The aim of this study was to assess the effects of tobacco smoking on the dorsum of the tongue and buccal epithelium. Methodology: This case control cross-sectional study was conducted with 174 smoking and non-smoking volunteers living in the city of Hail, Northern KSA. Cytological Materials were obtained from buccal mucosa and dorsum of the tongue, and assessed using cytopathological methods. Results: In buccal smears, cytological atypia was observed in 17 out of 101 (16.8%) smoker cases but only 3/73(4.1%) of the controls. For cytological atypia in buccal and tongue smears, the adjusted odd ratio (OR) and the 95% confidence interval (CI) were found to be 4.7 (1.3-16.8), P < 0.016)) and 4.3 (0.93- 20.2), P <0.06)), respectively, in the two sites. Conclusion: Tobacco smoking is a major risk factor for occurrence of cytological atypia, which might subsequently develop into oral precancerous and cancerous lesions. Oral exfoliative cytology is an easy and cheap non-invasive procedure which appears highly suitable for screening populations at risk of developing oral cancer.