• 제목/요약/키워드: Screening Method

검색결과 1,958건 처리시간 0.029초

DVSF: 가상 검색을 위한 분산 시스템 (DVSF: A Distributed System for Virtual Screening)

  • 황석찬;최종선;이상근;임재훈;최재영;노경태;이지수
    • 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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    • 제9권1호
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    • pp.25-32
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    • 2003
  • 오늘날 사람들의 많은 관심을 끌고 있는 생명 공학 분야에서, 가상 검색은 컴퓨터에서 가상적으로 시뮬레이션을 수행함으로서 특정 질병에 관여하는 물질을 널다 빠르게 추출하여 신약을 설계하는 방법이다. 본 논문에서는 지역적으로 분산된 유휴 또는 전략적 자원을 이용하여 가상 검색을 효과적으로 수행할 수 있는 분산 시스템인 DVSF(Distributed Virtual Screening Facilities)를 소개한다. DVSF는 중소규모의 실험실이 가지고 있는 유휴 자원을 이용하여 최소한의 비용으로 효과적인 신약 개발을 위한 환경을 구성할 수 있도록 개발되었다.

Comparison between analytic and numerical approaches to calculate screening current induced field in HTS magnet

  • Bang, Jeseok;Kim, Seokho;Kim, Jaemin;An, Soobin;Im, Chaemin;Hahn, Seungyong
    • 한국초전도ㆍ저온공학회논문지
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    • 제21권2호
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    • pp.45-49
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    • 2019
  • This paper reports comparison between analytic and numerical simulation approaches for calculation of screening current and screening current induced field in a high temperature superconductor magnet. Bean slab model is adopted to calculate screening current and SCF analytically, while the finite element method numerically. A case study of screening current and SCF calculation are conducted with a magnet, a 7 T 68 mm cold-bore multi-width no-insulation GdBCO magnet built and tested by Massachusetts Institute of Technology Francis Bitter Magnet Laboratory. In this study, we assume the magnet is dunked in liquid nitrogen at 77 K. Furthermore, the simulation results are compared in terms of computation time and accuracy. Finally, discussion on the different methods together with the comparison between the calculations and experiment is provided.

Cervical Cancer Screening in Korean American Women: Findings from Focus Group Interviews

  • Kim, Hoo-Ja;Lee, Kyung-Ja;Lee, Sun-Ock;Kim, Sung-Jae
    • 대한간호학회지
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    • 제34권4호
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    • pp.617-624
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    • 2004
  • Purpose. Korean American women have twice the rate of cervical cancer than white women and demonstrate low rates in participation in cervical cancer screening. This study was to describe the perceptions about cervical cancer and factors related to cervical cancer screening among Korean American women. Method. Focus group methods. Results. Five themes emerged. First, knowledge about cervical cancer; misconceptions about cervical cancer, its causes, reproductive anatomy and the treatment Second, perceived meanings of having cervical cancer; most of the women felt that cervical cancer represented a loss of femininity and existential value of woman-hood. Third, knowledge about cervical cancer screening; regular medical check-ups were necessary for early detection and prevention of cervical cancer. Forth, experiences and perceived meanings of cervical cancer screening; the participants expressed their feelings; embarrassment, fear, shame and shyness. Fifth, practices of cervical cancer screening; various intervals in participating in cervical cancer screening. But they mentioned several deterrents, language, insurance, time constraint, embarrassment, fear of the screening results, misbelief about susceptibility, lack of health prevention behavior, and lack of information written in Korean. Conclusion: Results emphasize the critical need for culturally appropriate health education to encourage participation of Korean American women in cervical cancer screening.

폭 변화에 따른 잠제의 파랑 차단 성능 (Wave Screening Performance of the Submerged Breakwater With Various Crown Widths)

  • 조원철
    • 한국해안해양공학회지
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    • 제16권4
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    • pp.206-212
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    • 2004
  • 본 연구에서는 폭이 좁은 1열 및 다열 잠제 대한 파랑 차단 성능을 폭이 넓은 1열 및 2열 잠제의 파랑 차단 성능과 비교$.$연구하였다. 파동장은 선형포텐셜 이론으로 모형화 하였으며 유한요소법을 적용하여 수치해석 하였다. 수치해석 결과, 1열 잠제에서는 폭이 좁은 잠제가 폭이 넓은 잠제보다 파랑 차단 성능이 다소 떨어지나 어느 정도 효과적인 파랑 차단 성능을 보여주고 있으며, 폭이 좁은 잠제를 2열 또는 3열로 배치하였을 때에는 폭이 넓은 1열 또는 2열 잠제보다 훨씬 뛰어난 파랑 차단 성능을 보이고 있다.

폐경여성들의 자궁경부암 검사 경험 (Experience of Cervical Cancer Screening among Menopausal Women)

  • 박소미;김현경
    • 여성건강간호학회지
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    • 제9권1호
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    • pp.28-38
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    • 2003
  • The purpose of this study was to explore the experience of Pap smear screening of menopausal women in W city using a phenomenological methodology. The participants were 5 focus groups consisting of 37 menopausal women. They were selected using snowball sampling method. The data were collected through focus group interviews. Data were recorded and analyzed by Colazzi's method. Significant statements were extracted from the data resulting in 20 themes. These themes formed 12 clusters and 5 categories. The essential themes of the experience of cervical cancer screening emerged as : "unpleasant feelings during procedure", "ambivalent feelings about results", "be guided to seek health", "shrink from interaction with health professionals", "at ease about cervical cancer". The results indicated that cervical cancer prevention strategies for menopausal women need to be based on deep under standing of the personal experiences of Pap smear screening. In conclusion, it is suggested that more specified strategies are needed for menopausal women to encourage them to have regular screening.

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트리즈로 분석한 코로나19 대응 선별진료소의 진화 (The Evolution of Screening Center for COVID-19 Analyzed by TRIZ)

  • 송창룡
    • 산업경영시스템학회지
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    • 제45권3호
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    • pp.139-149
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    • 2022
  • Korea's Corona 19(COVID-19) quarantine, referred to as 'K-Quarantine', is a globally recognized quarantine system that has achieved both conflicting goals: health and economy. The quarantine system represented by 3T(Test-Trace-Treat) is not a method of blocking an area, but a method of screening and treating infected and non-infected persons. The screening center, one of the key elements of this screening treatment system, has evolved to suit the timing and situation of COVID-19, and has succeeded in initial response by conducting large-scale tests quickly and safely. By analyzing the evolution of screening centers that produced such significant results from a problem-solving point of view, it proved its meaning as a practical success case of creative problem-solving. In addition, the usefulness of TRIZ (Russian abbreviation of Theory of Solving Inventive Problem), a creative problem-solving theory, was confirmed through an analysis of actual verified cases of COVID-19 response. TRIZ is a problem-solving theory created by analyzing the regularity of invention patents, and is widely used not only in the technical field but also in the non-technical fields such as design, management, and education. The results of this study are expected to provide useful meaning and practical examples to researchers interested in system analysis and TRIZ application from a problem-solving perspective.

An Automatic Strabismus Screening Method with Corneal Light Reflex based on Image Processing

  • Huang, Xi-Lang;Kim, Chang Zoo;Choi, Seon Han
    • 한국멀티미디어학회논문지
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    • 제24권5호
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    • pp.642-650
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    • 2021
  • Strabismus is one of the most common disease that might be associated with vision impairment. Especially in infants and children, it is critical to detect strabismus at an early age because uncorrected strabismus may go on to develop amblyopia. To this end, ophthalmologists usually perform the Hirschberg test, which observes corneal light reflex (CLR) to determine the presence and type of strabismus. However, this test is usually done manually in a hospital, which might be difficult for patients who live in a remote area with poor medical access. To address this issue, we propose an automatic strabismus screening method that calculates the CLR ratio to determine the presence of strabismus based on image processing. In particular, the method first employs a pre-trained face detection model and a 68 facial landmarks detector to extract the eye region image. The data points located in the limbus are then collected, and the least square method is applied to obtain the center coordinates of the iris. Finally, the coordinate of the reflective light point center within the iris is extracted and used to calculate the CLR ratio with the coordinate of iris edges. Experimental results with several images demonstrate that the proposed method can be a promising solution to provide strabismus screening for patients who cannot visit hospitals.

폴리그라프를 활용한 산업스파이 대응방안 (Polygraph Security Screening as an Internal Control Method to Counter Industrial Espionage in Korea)

  • 이주락
    • 시큐리티연구
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    • 제20호
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    • pp.291-311
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    • 2009
  • 치열한 국제 경제환경에서 첨단기술력의 확보는 국가와 기업의 경쟁력을 결정하는 가장 중요한 요소이다. 그동안 우리나라는 기술개발에 꾸준히 노력한 결과 세계적 수준의 첨단기술을 많이 보유하게 되었다. 그러나 이로 인해 우리나라의 기업이 산업스파이의 주요 표적이 되는 결과도 뒤따랐다. 그러므로 본 연구에서는 문헌조사방법을 통해 산업스파이 문제에 대한 내부통제 방안으로서 폴리그라프 보안검사를 살펴보고, 이의 도입 시 고려하여야 할 사항들에 대하여 검토하고자 하였다. 폴리그라프 보안검사는 처벌의 확실성과 신속성을 제고하여 우리사회에 억제효과를 발생시키므로 산업스파이 통제에 상당한 효과가 있을 것으로 기대된다. 그러나 이에는 검사의 오류로 인한 피해발생의 가능성도 함께 존재한다. 따라서 폴리그라프 보안검사는 다른 보안관리수단과 함께 사용되어질 때 오류로 인한 피해의 가능성을 최소화 할 수 있다. 또 검사의 도입에 앞서, 검사의 정확성에 영향을 미치는 요인인 대응수단과 검사자의 숙련도에 대하여도 충분히 대비하여야 한다. 본 연구에서는 검사의 정확성에 영향을 미치는 요인들을 중심으로 산업스파이 대응을 위한 폴리그라프 보안검사의 활용방안을 제시하였다.

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The Simple and Rough Screening Method of Phosphorus Deficient Tolerance Rice

  • Hwang, Woon-Ha;Kim, Dae-Wook;Jeong, Jae-Heok;Jeong, Han-Yong;Lee, Hyen-Seok;Choi, Kyung-Jin;Lee, Gun-Hwi;Lee, In-Jung;Oh, Sung-Hwan
    • 한국작물학회지
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    • 제60권4호
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    • pp.412-420
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    • 2015
  • Even though phosphorus (P) is essential element for plant growth and development, it is not enough for crop production in soil. To breed more P deficient tolerance rice, screening and selection in rice population is needed. We tried to develop more simple and rough screening method for breeding of P deficient tolerance rice. In P deficient condition, tiller number was dramatically decreased among yield components in rice. Though this result, we confirmed tiller number could be the best marker in screening of P deficient tolerance rice. 480 rice genetic resources were cultivated in rice bed tray filled with P deficient soil for four weeks and each dry weight was measured. Among them, the 55 kinds of genetic resource were selected then cultivated in paddy field with 3 fertilizer conditions. Plant dry weight and tiller number in ripening stage were shown significant difference according to P condition. Plant dry weight and tiller number in ripening stage was highly correlated especially in P deficient condition. Furthermore, the tiller number in ripening stage and plant dry weight in rough screening were shown high degree correlation. Though these results, we might expect measuring of plant dry weight after cultivation in rice bed tray filled with P deficient soil could be a simple and effective screening method in selection of P deficient tolerance rice.

발색법에 의한 Peroxidase의 신속한 스크리닝법과 2, 4-DCP 분해균주의 스크리닝 (Rapid Screening Method of Peroxidase by Colorimetric Assay and Screening of 2, 4-DCP Degradable Strains)

  • 류강;이은규
    • KSBB Journal
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    • 제23권6호
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    • pp.484-488
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    • 2008
  • 본 연구에서는 peroxidase 활성의 신속한 스크리닝을 위해 peroxidase의 활성을 정량적으로 평가할 수 있는 분석으로 agar plate와 96-well plate에서 peroxdase의 활성에 비례하여 색상감도를 측정할 수 있는 colorimetric 분석법을 개발하였다. 이 방법은 RP-HPLC 결과와 매우 비례적으로 상관적인 결과를 보였다. 이 colorimetric 분석법을 사용하여, 폐수에서 한천 고체배지에서 7회에 걸친 스크리닝으로 높은 농도의 2,4-DCP(1000 ppm)에서 생존하는 균주를 스크리닝하였고 선별된 이들 균주들은 탄소원으로 2,4-DCP 만을 대사할 수 있으며 높은 peroxidase 생산량을 보였다. 분리된 균주들 중 높은 peroxidase 활성을 가지는 2,4-DCP 분해 균주를 분리하였고 최종 분리된 균주는 염색폐수의 COD를 4시간 동안 44%에서 61%까지 제거하였다. 상기의 결과에 의해 본 연구에서 개발된 발색법이 페놀화합물 분해 균주 스크리닝법이 빠르고 쉬운 난분해성 물질인 페놀 혼합물의 분해 균주 탐색에 대하여 성공적으로 적용될 수 있기를 기대한다.