• 대한인간공학회지
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• 제29권1호
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• pp.113-120
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• 2010

This research is to evaluate the arousal level by using cardiovascular response. PPG was used in this study as one of the method of measuring it rather than ECG (Electrocardiography) for the purpose of solving ergonomic problem of sensing. The participants were in the age group of 20 (mean=24, standard deviation=1.25): five men and five women. Each experiment composed with four identical sets. First, a black screen was displayed for 30 second rest. Then, the prepared 6 pair images were randomly presented for 10 second stimulation and for 30 second non-stimulation. PPG was measured on the earlobes of experimenters at 200Hz sampling frequency. PPG amplitude, PPI(Pulse to Pulse Interval), and PRV(Pulse Rate Variability) were analyzed according to arousal level. T-test was performed to compare between the PPG variables of rest and relaxation, rest and arousal, and relaxation and arousal. Relative to the rest state, PPG amplitude decreased in relaxed state and increased in aroused state. Relative to the rest state, PPI decreased in both emotional states. However, more significant decline was observed in aroused state. PRV's LF and HF were used in the form of LF/HF to compare between the relaxed and the aroused state. Therefore, PPG signal showed significant differences between relaxed and aroused state. In conclusion, evaluation of human arousal level used in the PPG analysis demonstrated that PPG has better usability and comforter measurement than ECG and is clearly an alternative method of measuring arousal level.

• Journal of the Korean Data and Information Science Society
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• 제24권6호
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• pp.1359-1368
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• 2013

대학 입학사정관제는 기존의 대학입학제도에 대한 개선 방안으로 수능 위주의 학생선발에서 벗어나 학생부 (교과와 비교과)와 학생의 잠재력, 대학의 설립이념 등을 고려하여 대학입학제도에 대한 패러다임을 전환하려는 의도에서 도입되었다. 입학사정관제의 특징 중에 하나는 입학사정관제도에 의해서 선발된 학생들을 선발자체에 그치지 않고 추후 관리를 통하여 창의적인 인재를 육성하고자 하는 것이다. 통상적으로 입학사정관제도에 의한 학생선발은 학생부 (서류전형)와 발표 토론 및 면접 등의 내용을 토대로 선발된다. 입학사정관제에 의한 학생들에 대한 평가는 주로 정성적인 평가이기 때문에 평가를 하는데 있어서 입학사정관의 주관이 개입되어 학생선발에 있어서 객관성이 떨어질 수 있다는 문제점이 제기된다. 본 연구에서는 이러한 입학사정관제에 의한 학생선발 과정에 있어서 학생들이 불이익을 받지 않도록 학생선발의 객관성을 유지할 수 있는 알고리즘을 제시한다.

• 한국환경보건학회지
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• 제43권2호
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• pp.122-129
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• 2017

Objectives: Most of the $PM_{10}$ in subway stations is spread by the train-induced wind from the tunnels. Therefore, in order to improve air quality in subway stations, it is important to remove the $PM_{10}$ from the tunnels. After the installation of PSD (platform screen doors), the influence of train-induced wind and $PM_{10}$ at the platform has decreased, but is estimated to have increased in subway tunnels. This study was conducted to investigate the control of $PM_{10}$ in subway tunnels by applying a 500-fold diluted solution mixed with a humectant using a natural polymer. Methods: For this purpose, we tested the dust reduction effect in a laboratory and corrosion test and water pollution using fish and aquatic plants for the natural dust collecting agent. In the tunnel of a subway station, we used the natural dust collecting agent over 15 days. The study was carried out on $PM_{10}$ control during operation, which accounts for more than 70% of subway dust. Results: As results, the natural dust collecting agent exhibited an excellent dust control effect, and it was safe for water quality and soil. It showed the effect of controlling $PM_{10}$ in the subway tunnel by 49.5- 64.7% over 15 days. The use of the dust collecting agent for the control of $PM_{10}$ could be confirmed in the subway. Conclusion: It is necessary to clearly explain the major portions of chemical components contained in $PM_{10}$ to figure out the characteristics of $PM_{10}$ and to develop effective reduction measures to decrease the adverse effects of $PM_{10}$ in the subway.

• 한국HCI학회논문지
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• 제5권2호
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• pp.1-6
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• 2010

본 연구에서는 장애인이나 게이머를 위해 눈의 움직임과 머리의 움직임으로 제어가 가능한 헤드 마우스를 제안하였고, 제안한 마우스를 기존의 마우스와 비교하였다. 마우스 포인터의 이동은 머리 움직임의 회전각도 정보를 활용하였고, 클릭이나 더블 클릭의 이벤트는 눈의 깜빡임을 이용하였다. 기존의 각속도계를 이용한 마우스에서 적분으로 인한 누적오차는 적분을 하지 않고 데드 존을 갖는 비선형 상대 좌표계 방식을 통하여 해결하였고, 추가적으로 이동 거리와 가속도를 함께 고려하여 직관적인 마우스 포인터 제어가 가능하도록 하였다. 주변광의 영향을 최소화하도록 광원 제어 회로를 설계하여 외부 광원의 변화에도 마우스 이벤트 검출에 영향을 받지 않도록 하였다. 제안한 마우스를 응시점을 이용한 마우스(퀵글랜스)와 비교한 결과, 20회 클릭하는 실험에서는 약 21%, Dasher를 이용한 문자입력실험에서도 약 25%, 화상키보드를 이용한 문자입력 실험에서도 약 37% 짧은 입력 시간을 보였다. 그리고 카메라 마우스와의 비교에서도 제안한 헤드 마우스가 우수한 성능을 보였다.

• Geomechanics and Engineering
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• 제14권3호
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• pp.271-281
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• 2018

A jointed rock slope stability evaluation was simulated by a discontinuous deformation analysis numerical method to investigate the process and safety factors for different crack distributions and different overloading situations. An optimized method using Discontinuous Deformation Analysis for Rock Failure (DDARF) is presented to perform numerical investigations on the jointed rock slope stability evaluation of the Dagangshan hydropower station. During the pre-processing of establishing the numerical model, an integrated software system including AutoCAD, Screen Capture, and Excel is adopted to facilitate the implementation of the numerical model with random joint network. These optimizations during the pre-processing stage of DDARF can remarkably improve the simulation efficiency, making it possible for complex model calculation. In the numerical investigations on the jointed rock slope stability evaluations using the optimized DDARF, three calculation schemes have been taken into account in the numerical model: (I) no joint; (II) two sets of regular parallel joints; and (III) multiple sets of random joints. This model is capable of replicating the entire processes including crack initiation, propagation, formation of shear zones, and local failures, and thus is able to provide constructive suggestions to supporting schemes for the slope. Meanwhile, the overloading numerical simulations under the same three schemes have also been performed. Overloading safety factors of the three schemes are 5.68, 2.42 and 1.39, respectively, which are obtained by analyzing the displacement evolutions of key monitoring points during overloading.

• Asian Pacific Journal of Cancer Prevention
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• 제16권13호
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• pp.5181-5185
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• 2015

Background: CCAT1 has been reported to be linked with pathogenesis of malignancies including colon cancer and gastric cancer. However, the regulatory effect of CCAT1 in hepatocellular carcinoma (HCC) remains unclear. The purpose of this research was to identify any role of CCAT1 in the progression of HCC. Materials and Methods: Real time-PCR was performed to test the relative expression of CCAT1 in HCC tissues. A computation screen of CCAT1 promoter was conducted to search for transcription-factor-binding sites. The association of c-Myc with CCAT1 promoter in vivo was tested by Pearson correlation analysis and chromatin immunoprecipitation assay. Additionally, Kaplan-Meier analysis and Cox proportional hazards analyses were performed. Results: c-Myc directly binds to the E-box element in the promoter region of CCAT, and when ectopically expressed increases promoter activity and expression of CCAT1. Moreover, Kaplan-Meier analysis demonstrated that the patients with low expression of CCAT1 demonstrated better overall and relapse-free survival compared with the high expression group. Cox proportional hazards analyses showed that CCAT1 expression was an independent prognostic factor for HCC patients. Conclusions: The findings demonstrated CCAT1, acting as a potential biomarker in predicting the prognosis of HCC, is regulated by c-Myc.

• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10809-10812
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• 2015

Background: Human papillomavirus (HPV) DNA testing is an effective method to screen for precancerous changes in the cervix. Samples from self-collection rather than Pap smear can potentially be used to test for HPV as they are more acceptable and preferred for use in certain settings. The objective of this study was to compare HPV DNA testing from self-collected vaginal swabs and physician-collected cervical swabs. Materials and Methods: A total of 101 self-collected vaginal and physician-collected cervical swabs of known cytology from Thai women were tested by electrochemical DNA chip assay. The specimens were divided into 4 groups: 29 with normal cytology, 14 with atypical squamous cells of undetermined significance (ASCUS), 48 with low-grade squamous intraepithelial lesion (LSIL), and 10 with high-grade squamous intraepithelial lesion (HSIL). Results: Positive detection rates of HPV from self-collected swabs were similar to those from physician-collected swabs. Among specimens with abnormal cytology, HPV was found in 50% of self-collected swabs and 47.2% of physician-collected swabs. In specimens with normal cytology, 17.2% of self-collected swabs and 24.1% of physician-collected swabs were positive for HPV. Concordance was relatively high between results from self-collected and physician-collected samples. The most common HPV genotype detected was HPV 51. Conclusions: HPV DNA testing using self-collected swabs is a feasible alternative to encourage and increase screening for cervical cancer in a population who might otherwise avoid this important preventive examination due to embarrassment, discomfort, and anxiety.

• 방송공학회논문지
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• 제25권1호
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• pp.113-116
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• 2020

본 논문은 360도 동영상과 감각효과(Sensorial Effects)가 피실험자의 몰입도, 만족도, 실재감에 미치는 영향을 측정하기 위한 사용자 경험(Quality of Experience: QoE) 평가 실험 방법을 제안한다. 피실험자는 발향장치가 부착된 헤드 마운티드 디스플레이(Head Mounted Display: HMD)를 착용한 상태에서 감각효과가 동반된 360도 동영상을 경험한 후, 몰입도, 만족도, 실재감에 대한 설문에 응답한다. 응답 분석 결과 제안된 실험방법이 360도 VR 동영상과 감각효과에 대한 피실험자의 몰입도, 만족도, 실재감 등을 측정하기에 적합한 실험 방법임을 확인하였다. 반면, 360도 동영상을 시청하는 도중 비교 실험을 위한 회색 화면을 삽입하게 되면 몰입도와 실재감에 상당한 저하를 일으키는 것으로 파악되었다.

• 대한의생명과학회지
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• 제19권4호
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• pp.315-329
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• 2013

This study was conducted to evaluate the distribution, frequency, sensitization rate, and types of specific allergen in allergic patients. We analyzed allergens of 12,882 allergic patient's serum referred for Medical Laboratory using MAST Allergy Screen Test (Inhalation/food panel) from April, 2010 to March, 2011. Allergen reactivity were not detected in 833/12,882 (6.5%) allergic patients and the other allergic patients had two or more types of allergens of food and inhalant, respectively. In the distribution of the allergen food 73.4% (9,450/12,882 patients) was much higher than the pollen 26.6% (3,432/12,882 patients). The sensitization rate to each allergen showed garlic 26.7%, egg white 21.5% of food allergens, mugwort 24.9%, ragweed short 19.6% of pollen allergens, Candida albicans 10.5%, Alternaria spp. 7.9% of fungus allergens, and showed high sensitized rate to Dermatophagoides farinae 90.2%, Dermatophagoides pteronyssinus 77.8%, house dust 57% of indoor allergens, respectively. The specific allergens of food allergen, fungus allergen, and indoor allergen were more frequent in young child than adult, but pollen allergens were frequent in adult than young child. In seasonal distribution, the food allergen were frequent in summer and autumn, the pollen allergen in autumn, fungus allergen in spring and in winter, and indoor allergen in autumn and in winter. In conclusion, the mite of Dermatophagoides farinae and Dermatophagoides pteronyssinus, and house dust showed the highest sensitization rate in specific allergen of allergic patients. The allergens showed difference feature according to the age, region, and types of allergen.

• 한국균학회지
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• 제14권4호
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• pp.265-271
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• 1986

털목이버섯의 저분자 독성물질로부터 다음과 같은 결론을 얻었다. 털목이버섯 열수추출액의 $LD_{50}$은 복강 및 경구투여시 각각 1.25와 4.18 g/kg이었다. 건조 털목이버섯 100 g에는 650$\sim$700 mouse lethal unit(=MLU)이 함유되어 있었다. 열수총추출액, C분흑 및 최종성분의 1 MLU는 각각 및 28.5, 25.0 및 12.0 mg/mouse이었다. 독성물질의 일반적일 증상은 행동둔화, 체모기립, 전율, 두부진동, 안구돌출, 사지마비, 사망직전의 급격한 다리운동 및 호흡마비 등이었다.