• 정보교육학회논문지
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• 제18권4호
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• pp.461-470
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• 2014

본 논문은 스크래치데이 행사에 참여한 초등학생과 중학생을 대상으로 SW 교육에 대한 인식을 조사하였다. 2013, 2014년에 실시된 스크래치 행사에 참여한 558명의 학생에게 창의컴퓨팅 교육을 실시하고, 학생들의 인식을 묻는 설문을 통하여 우리나라 SW 교육의 인식을 파악, 분석하였다. 분석 결과, 학생들은 창의컴퓨팅 교육을 재미있고, 유용하다고 생각하고 있으며, 학교교육에서도 교육이 이루어지기를 희망하고 있었다. 또한, 사용의도 측면에서는 남학생이 여학생보다 긍정적으로 인식하고 있었으며, 사전에 스크래치 교육을 경험한 학생들이 그렇지 않은 학생들보다 유용성, 사용의도에서 더 긍정적으로 인식하고 있었다. 구조방정식 모형 분석에서는 창의컴퓨팅 교육의 재미, 용이성, 유용성이 학교교육에 적용해야 한다는 인식에 영향을 주는 것으로 나타났다. 이를 통해 SW교육이 초 중등 교육에서 필요하며 학교 현장에서 적용 가능성을 도출하였다.

• 한국임상수의학회지
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• 제27권4호
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• pp.311-314
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• 2010

Bartonella henselae 는 고양이할큄병의 원인체이다. 고양이가 Bartonella spp.의 주된 보유숙주이기는 하지만, 최근 애완견의 할큄에 의한 고양이할큄병 발생이 보고되었다. 8두의 개에 1 ml의 인산완충식염수에 부유한 $2{\times}10^8CFU$의 B. henselae Houston-1을 0일에 피내주사하고, 동량을 21, 28, 36, 58, 64일째에 추가로 피내주사 하였다. B. henselae 감염을 nested PCR을 통해 확인하였다. B. henselae-PCR 양성군이 음성군에 비해 B. henselae로 말초혈액단 핵구를 자극한 후 얻은 배양상청액에서의 IFN-$\gamma$ 농도가 유의성 있게 높았다. B. henselae자극시, Th1활성을 보이는 개 말초혈액단핵구의 면역양상은 Th2활성을 보인다고 알려진 고양이와는 다른 것으로 보인다.

• 한국컴퓨터정보학회논문지
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• 제26권4호
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• pp.133-142
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• 2021

본 연구의 목적은 여성노인을 대상으로 모던댄스, 아쿠아로빅, 복합운동 프로그램을 실시한 후 신체조성과 신체기능체력에 대한 변화 비교하여 여성노인에게 가장 적합한 운동이 무엇인지를 살펴보고자 실시되었다. 연구의 대상자는 J도에 거주하는 노인여성 47명을 대상으로 MDG(n=13) AEG(n=11), CEG(n=11), CG(n=12)을 무작위로 집단을 모집하여 12주간 주3회 1시간씩 운동을 실시하였다. 이 연구의 결과 통제그룹에 비해 grip strength, chair stand, arm curl, 2 minute step, 244cm up and go에서 유의한 차이를 보였으며, Back scratch는 MDG와 CEG에서만 운동 후 유의하게 감소하였으나 Chair sit and reach에서는 변화가 보이지 않았다. 본 연구결과 운동그룹 중 모던댄스(MDG)가 운동 후 가장 많은 신체기능체력이 향상된 것으로 나타났으며, 노인들에게 유연성과 관절의 가동성을 증진 시킬 수 있는 추가적인 운동프로그램이 필요하다. 또한 자신의 흥미에 맞는 운동을 자발적으로 참여하여 지속성 있게 하는 것이 중요할 것으로 생각된다.

• 산업경영시스템학회지
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• 제43권4호
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• pp.116-122
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• 2020

Human and material resource planning is one representative example of Operations Research. Resource planning is important not only in civilian settings but also in military ones. In the Air Force, flight scheduling is one of the primary issues that must be addressed by the personnel who are connected to flight missions. However, although the topic is of great importance, relatively few studies have attempted to resolve the problem on a scientific basis. Each flight squadron has its own scheduling officers who manually draw up the flight schedules each day. While mistakes may not occur while drafting schedules, officers may experience difficulties in systematically adjusting to them. To increase efficiency in this context, this study proposes a mathematical model based on a binary variable. This model automatically drafts flight schedules considering pilot's mission efficiency. Furthermore, it also recommends that schedules be drawn up monthly and updated weekly, rather than being drafted from scratch each day. This will enable easier control when taking the various relevant factors into account. The model incorporates several parameters, such as matching of the main pilots and co-pilots, turn around time, availability of pilots and aircraft, monthly requirements of each flight mission, and maximum/minimum number of sorties that would be flown per week. The optimal solution to this model demonstrated an average improvement of nearly 47% compared with other feasible solutions.

• 한국재료학회지
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• 제16권10호
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• pp.606-613
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• 2006

This study was purposed to evaluate the influence of anodically oxidized film on titanium (Ti) onto MG-63 osteoblast-like cell attachment and activity. Only scratch lines created by polishing were seen in ASR and ANO-1 groups. About $1.5{\mu}m$-thick homogeneous oxide film which has pores of about $0.5{\mu}m$ diameter were formed in ANO-12. The crystalline structure of the oxide films formed by anodization in phosphoric acid electrolyte was $TiP_2O_7$. The total protein amounts of ANO-1 and ANO-12 groups showed higher values of maximum protein amount than that of AS-R group. At 3 days of incubation, total protein amount showed higher value in ANO-2 when comparing to that of AS-R (p<0.05). Based on the results of ALPase activity test, the degree of MG-63 cell differentiation for initial mineralization matrix formation was similar. For all the test groups after 1 day of incubation, MG-63 cells grew healthily in mono-layer with dendritic extensions. After incubation for 3 days, the specimen surfaces were covered more densely by cells, and numerous micro filaments were extruding to the extracellular matrix.

• Toxicological Research
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• 제22권3호
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• pp.221-228
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• 2006

Bonogen shampoo is composed of several plant extracts which are known to be used in oriental medicine. This study was carried out to investigate the effects of Bonogen shampoo on hair growth in an alopecia model of C57BL/6 mice. There were eight male and female experimental groups including distilled water(DW: negative control), a commercial shampoo[M], 3% minoxidil (MXD) and Bonogen shampoo(BNG). Dorsal skin hair of six-week-old mice was trimmed with an electric clipper carefully not to damage the skin. The next day, mice without skin scratch were selected, randomized and separated in 10 mice per group. The test compounds were topically treated with 0.15 ml per mouse or dorsal skin for 21 days daily and then washed thoroughly with DW. The hair regrowth was determined photographically at 0, 4, 7, 10, 15, 18, and 21 days and histologically at day 21. No clinical signs were observed in all mice. Although body weight was slightly increased in 3% MXD group than other groups, it was not significant. Hair regrowth began to be promoted after 14 days and appeared a distinct regrowth pattern in all animals by topical treatment of test compounds at 18 days. In particular, the topical treatment of bonogen shampoo or 3% MXD for 21 days to dorsal skin accelerated hair regrowth faster than DW or M shampoo. At 21 days, the hair regrowth promotion speed was in order of 3% MXD>BNG>M>DW. The bonogen shampoo or 3% MXD also promoted hair follicle elongation compared to the negative control. These results suggest that bonogen shampoo has hair growth promoting activities and may be useful for treatment of bald or alopecia.

• 대한소아치과학회지
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• 제29권3호
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• pp.362-370
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• 2002

최근 20년간 다양한 종류의 심미 수복재가 개발되었고, 특히 지난 5년 동안에는 그 수에 있어서 극적인 증가추세를 보였다. 최근 들어, ormocer라는 새로운 종류의 광중합형 수복재료가 소개되었는데, 화학 분야에서는 이미 오래 전부터 알려져 있던 성분으로, 광학렌즈 등의 표면경화제로 이용되어 오다가 최근 치과용 수복재에 도입되었다. 'Ormocer' 란 'Organically Modified Ceramics'의 약자로 'Ormosils' (Organically Modified Silicates)로도 알려져 있다. 그러나, 이 새로운 수복재에 대한 연구는 아직 미흡한 실정이다. 본 연구에서는 서로 다른 계통의 광중합형 수복재들(Z-100, Surefil, Tetric Ceram, Dyract AP)과 ormocer(Admira)를 압축강도와 굴곡강도 측면에서 비교 평가하고, 구강내 환경과 유사한 조건에서 수분흡수가 그 물성에 미치는 영향을 평가할 목적으로 시도되어 다음과 같은 결과를 얻었다. 1. 1일 후에 측정한 Admira의 압축강도는 Surefil보다는 낮았으나, 다른 재료들과는 유의한 차이를 나타내지 않았다(p>0.05). 2. 1일 후에 측정한 Admira의 굴곡강도는 다른 4종의 재료에 비해서 낮았다(p<0.05). 2일부터는 3종의 복합레진에 비해서 낮았다(p<0.05). 3. 실험기간(30일) 중 hybrid composite resin군(Z-100, Tetric Ceram)과 packable resin(Surefil)군 간에는 압축강도와 굴곡강도에서 유의한 차이가 없었다(p>0.05). 4. 실험에 사용된 5종의 수복재 모두 압축강도와 굴곡강도가 2일까지 증가하다가 7일부터 감소하였다(p<0.05). 5. 각 재료의 시간에 따른 압축강도와 굴곡강도의 변화양상은 통계적으로 유사하였다(p>0.05).

• BMB Reports
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• 제52권4호
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• pp.289-294
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• 2019

The present study evaluated the role of AHNAK in Bartonella henselae infection. Mice were intraperitoneally inoculated with $2{\times}10^8$ colony-forming units of B. henselae Houston-1 on day 0 and subsequently on day 10. Blood and tissue samples of the mice were collected 8 days after the final B. henselae injection. B. henselae infection in the liver of Ahnak-knockout and wild-type mice was confirmed by performing polymerase chain reaction, with Bartonella adhesion A as a marker. The proportion of B. henselae-infected cells increased in the liver of the Ahnak-knockout mice. Granulomatous lesions, inflammatory cytokine levels, and liver enzyme levels were also higher in the liver of the Ahnak-knockout mice than in the liver of the wild-type mice, indicating that Ahnak deletion accelerated B. henselae infection. The proportion of CD4+interferon-${\gamma}$ ($IFN-{\gamma}^+$) and $CD4^+$ interleukin $(IL)-4^+$ cells was significantly lower in the B. henselae-infected Ahnak-knockout mice than in the B. henselae-infected wild-type mice. In vitro stimulation with B. henselae significantly increased $IFN-{\gamma}$ and IL-4 secretion in the splenocytes obtained from the B. henselae-infected wild-type mice, but did not increase $IFN-{\gamma}$ and IL-4 secretion in the splenocytes obtained from the B. henselae-infected Ahnak-KO mice. In contrast, $IL-1{\alpha}$, $IL-1{\beta}$, IL-6, IL-10, RANTES, and tumor necrosis $factor-{\alpha}$ secretion was significantly elevated in the splenocytes obtained from both B. henselae-infected wild-type and Ahnak-knockout mice. These results indicate that Ahnak deletion promotes B. henselae infection. Impaired $IFN-{\gamma}$ and IL-4 secretion in the Ahnak-knockout mice suggests the impairment of Th1 and Th2 immunity in these mice.

• Strategy21
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• 통권37호
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• pp.5-31
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• 2015

The Republic of Korean Navy (ROKN) started from scratch. However, ROKN demonstrated its Blue Navy capabilities successfully to the entire world by conducting "Operation Early Dawn" at the Aden Bay, Yemen in Jan 2011. On the event of the 70th anniversary of the ROKN, I would like to retrospect past gleaning from voyages and challenges we had in the past. At the very inception of the ROKN, Korean government as well as senior military leaders recognized that it had no time to spare to clean up military those were insinuated deeply by communist agents. It was the top priority of the government. The Mongumpo Operation which was not well known, conducted by ROKN was one of the clean-up drive. The Korean War sometimes called as "a fire from land put-off at the sea". The world famous "Incheon Landing" which reversed war situation from the Nakdong Perimeter also done by Sea Power. ROKN conducted various maritime operations including not only Incheon Landing, but amphibious operation at Hungnam, mine sweeping, sea convoy, Wonsan Withdrawal. On the same day of the Korean War started, 25th June 1950, unless the victory of the ROKNS Baekdusan (PC 701) at the Korean Strait, the waning lamp light of Korea could not be rekindled by the participation of the U.N. The ROKN rescued the 17th regiment of Korean Army from the isolation at the Ongjin Peninsular and transported gold and silver bars stored at the Bank of Korea to the Navy supply deposit in Jinhae safely. ROKN special intelligence unit conducted critical HUMINT which led Incheon Landing success. One of important mission ROKN conducted successfully was not only transporting war fighting materials but also U.S. provided grains to starving Koreans. ROKN participated Vietnam campaign from 1960s and conducted numerous maritime transportation operations supplying materials to Vietnam military forces along the long coastal lines. Experienced Naval Officers and enlisted men who discharged and acquired as merchant marine certificate supported most of the U.S. sea lift operations throughout the Vietnam campaign. ROK-US Combined Forces which had been honed and improved its war fighting capabilities through the Korean War and out of Vietnam jungle playing key deterrent against threat from north Korea. However, those threat level will be completely different when north Korea finish its nuclear weapon ambition. In order to stand firm against north Korean nuclear threat, I would like to expect strong political leadership supporting nuclear submarine for ROKN.