• Title/Summary/Keyword: Scoring function

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Reliability Evaluation for the Advanced Pressurized water Reactor 1400 (신형경수로 1400을 위한 신뢰성 평가)

  • 강영식
    • Journal of the Korean Society of Safety
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    • v.16 no.3
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    • pp.125-134
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    • 2001
  • The Advanced Pressurized rater Reactor 1400(APR1400) system is advanced of the successful Korean Nuclear Power Plants(KSNP) design which meets functional needs for safety enhancement reliability improvement, and control in the human-computer monitoring system. Therefore this paper describes the scoring model in order to justify the reliability and safety in APR 1400 under uncertainty. The structure of this paper consists of the human engineering, risk safety, quality function, safety organization management factors of the qualitative factors in chapter 2, and the expectation results of the normalized scoring model in chapter 3. Finally, the proposed reliability model have provided the technical flexibility not only for functional control fields but also for accidents protection systems in APR 1400 under uncertainty.

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Determining Soil Quality of Heavy Metal Contaminated Agricultural Field in Korea (중금속 오염 농경지 토양의 토양질 평가에 관한 연구)

  • Kim, Ju Hee;Chung, Doug Young;Oh, Se Jin;Kim, Rog Young;Yang, Jae E.;Park, Gwan In;Lee, Jin Soo;Kim, Sung Chul
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.6
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    • pp.1237-1241
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    • 2012
  • Heavy metal pollution in agricultural field has been a critical issue in worldwide. For this reason, remediation technologies for heavy metal polluted soil are applied especially near at the abandoned metal mine. Soil quality analysis is also an important factor for proper management in heavy metal polluted agricultural field. In this study, scoring function was utilized to evaluate soil quality in heavy metal polluted agricultural field. Among other soil properties, bulk density, soil pH, EC, $NH_4$-N, $NO_3$-N, and cation exchange capacity (CEC) were determined for minimum data set (MDS) with principal component analysis. Result showed that both upland and paddy soil contaminated with heavy metal were not suitable for crop growth except scoring of soil pH for paddy soil and CEC for upland soil. This result might indicate that chemical stabilization technology with chemical amendment could be adapted for remediation method for heavy metal polluted agiclutural field not only for heavy metal immobilization but also enhancement of soil condition for crop growth.

Survival-Related Factors of Spinal Metastasis with Hepatocellular Carcinoma in Current Surgical Treatment Modalities : A Single Institute Experience

  • Lee, Min Ho;Lee, Sun-Ho;Kim, Eun-Sang;Eoh, Whan;Chung, Sung-Soo;Lee, Chong-Suh
    • Journal of Korean Neurosurgical Society
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    • v.58 no.5
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    • pp.448-453
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    • 2015
  • Objective : Recently, the survival of patients with hepatocellular carcinoma (HCC) has been prolonged with improvements in various diagnostic tools and medical treatment modalities. Consequently, spine metastases from HCC are being diagnosed more frequently. The accurate prediction of prognosis plays a critical role in determining a patient's treatment plan, including surgery for patients with spinal metastases of HCC. We investigated the clinical features, surgical outcomes, and prognostic factors of HCC presenting with spine metastases, in patients who underwent surgery. Methods : A retrospective review was conducted on 33 HCC patients who underwent 36 operations (three patients underwent surgical treatment twice) from February 2006 to December 2013. The median age of the patients was 56 years old (range, 28 to 71; male : female=30 : 3). Results : Overall survival was not correlated with age, sex, level of metastases, preoperative Child-Pugh classification, preoperative ambulatory function, preoperative radiotherapy, type of operation, administration of Sorafenib, or the Tokuhashi scoring system. Only the Tomita scoring system was shown to be an independent prognostic factor for overall survival. Comparing the Child-Pugh classification and ambulatory ability, there were no statistically differences between patients pre- and post-operatively. Conclusion : The Tomita scoring system represents a practicable and highly predictive prognostic tool. Even though surgical intervention may not restore ambulatory function, it should be considered to prevent deterioration of the patient's overall condition. Additionally, aggressive management may be needed if there is any ambulatory ability remaining.

Quality Assessment of the Soils Used for Urban Agriculture in Seoul and its Vicinity

  • Lim, Ga-Hee;Park, Sol-Yi;Jeon, Da-Som;Yoon, Jung-Hwan;Lee, Dan-Bi;Oh, Jun-Seok;Kim, Kye-Hoon
    • Korean Journal of Soil Science and Fertilizer
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    • v.49 no.5
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    • pp.572-576
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    • 2016
  • Soil quality assessment is an important tool for environmental management in an agricultural field. It can be used to evaluate the health of the soils and to establish the basis for sustainable urban agriculture and soil management. For this study, the chemical properties of the soils used for urban agriculture were examined. Results of the soil analysis for chemical properties were applied to soil quality assessment system, which is composed of principal component analysis, application to scoring function and derivation of soil quality index (SQI). Soil pH, electrical conductivity (EC), organic matter (OM), total nitrogen (T-N) were determined for minimum data set (MDS) according to principal component analysis. Based on the results of scoring for four indicators (pH, EC, OM, T-N), soil pH was the indicator that needs the most urgent management. Results of SQI derivation showed that many of the urban farms appeared to be insufficient score in comprehensive soil quality assessment. In conclusion, soil management practices based on scores derived from soil chemical indicators need to be carried out to maintain sustainable urban agricultural soil environment and to provide easy-to-understand information to urban farmers.

Cooperative Control of the Multi-Agent System for Teleoperation (원격조종 다개체 로봇의 협동제어)

  • 황정훈;권동수
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.154-154
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    • 2000
  • The cooperative strategy for the teleoperated multi-agent system is presented. And this scheme has been applied to the teleoperated robot soccer system that is newly proposed. For the teleoperated robot soccer system, we made mapping functions to control a 2-wheeled mobile robot using a 2 DoF stickcontroller. The simulation with a real stickcontroller has been evaluated the performance of the proposed mapping function. Then, the basic cooperation strategy has been tested between teleoperated robot and autonomous robot It is shown that the multi-agent system for teleoperation can have a good performance for a job Like a scoring a goal

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양자역학으로 π-π interaction 에너지 계산을 통한 ligand binding energy 분석

  • Lee, Seung-Jin;Yun, Ji-Hui;Jang, Seong-Min;Cho, Art E.
    • Proceeding of EDISON Challenge
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    • 2013.04a
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    • pp.89-100
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    • 2013
  • 생물정보학의 다양한 이론적 내용과 계산적 방법들이 갈수록 전문화 되어짐에 따라 신약 개발, 신 물질 합성, 단백질의 구조 예측 등 다양한 분야에서 필요성이 커져가고 있다. 이 중 molecular docking 기술은 단백질과 특정 분자간의 결합 형태를 분자 모델링 기법을 통해 알아내는 방법이며 신약개발 연구에 큰 영향을 미치고 있다. Molecular docking을 통하여 분자간의 결합 형태를 예측하는 과정에서 Protein-ligand complex의 정확한 에너지 측정을 가능하게 하는 scoring function이 필요하다. 그런데 본 연구에서 사용한 B-Raf kinase protein 은 active site 부분에서 ligand와 receptor 간에 aromatic ring로 인한 ${\pi}-{\pi}$ interaction이 정확한 에너지 계산을 어렵게 한다. 이러한 ${\pi}-{\pi}$ interaction 부분의 에너지를 정확하게 계산하기 위해 양자역학 계산을 실시하였다. Active site 부분에서 ligand와 receptor에서 발생하는 각각 다른 5개의 ${\pi}-{\pi}$ interaction 구조를 준비하여 Gaussian을 통해 양자역학 에너지를 계산하였다. 그리고 이러한 결과 값들이 ligand의 활성 값과 어떤 상관관계를 갖는지 살펴보았다. 그 결과 ${\pi}-{\pi}$ interaction을 양자역학으로 계산한 값이 그렇지 않은 것보다 더 좋은 상관관계를 보여주었다. 이는 특별한 구조의 영향으로 ligand와 receptor 간의 결합에너지를 정확하게 계산하기 어려운 문제에서 양자역학을 적용할 경우 더욱 좋은 결과값을 얻을 수 있었다. 또한 이러한 데이터가 신 물질 개발이나 신약 개발 등의 다양한 분야에서 계산화학 방법이 신뢰성을 얻는데 도움 될 수 있다고 생각된다.

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Clinical Study of Oriental Medical Treatment on a Patient with Alcoholic Polyneuropathy (알코올성 다발성 신경병증의 한방치료 효과)

  • Yeom, Seung Ryong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.5
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    • pp.797-802
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    • 2012
  • Alcoholic polyneuropathy is a disorder of the peripheral nervous system that interferes with sensory, motor, and autonomic nerve function. This study was to report the effect of Oriental medical treatment on a patient with alcoholic polyneuropathy. Conservative Oriental medical treatment was done to a man of 84 years who was diagnosed as a alcoholic polyneuropathy and suffered from both distal dominant leg weakness & symmetrical paresthesia and ataxic gait. The changes of symptoms, reflexes and sensory test were checked by Toronto Clinical Neuropathy Scoring System(TCNSS). Reflexes, motor and sensory impairments were improved after the Oriental medical treatment. I reported good effects of Oriental medical treatment on alcoholic polyneuropathy. Oriental medical treatment can be helpful to improve the symptoms of alcoholic polyneuropathy.

Application of Docking Methods: An Effective In Silico Tool for Drug Design

  • Kulkarni, Seema;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.6 no.2
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    • pp.100-103
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    • 2013
  • Using computational approaches we can dock small molecules into the structures of Macromolecular targets and then score their potential complementarity to binding sites is widely used in hit identification and lead optimization techniques. This review seeks to provide the application of docking in structure-based drug design (binding mode prediction, Lead Identification and Lead optimization), and also discussed how to manage errors in docking methodology in order to overcome certain limitations of docking and scoring algorithm.

Analysis of Scoring Difficulty in Different Match Situations in Relation to First Athlete to Score in World Taekwondo Athletes (세계태권도 겨루기 선수들의 선제득점에 따른 경기 내용별 득점 난이도 분석)

  • Mi-Na Jin;Jung-Hyun Yun;Chang-Jin Lee
    • Journal of Industrial Convergence
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    • v.22 no.4
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    • pp.21-29
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    • 2024
  • This study analyzed the difficulty of scoring in different match situations in relation to which competitor scored first. The study analyzed the data from the 2022 Guadalajara World Taekwondo Championships. The analysis was performed for two separate weight classes: lightweight and heavyweight. Four game content variables were used: whether the athlete scored first, attack type, attack area, and game situation. Descriptive statistics, the Rasch model, and discrimination function questions were applied for data processing. SPSS and Winsteps were used for the statistical analysis, and the statistical significance level was set at 0.05. Consequently, in the lightweight class, the scoring frequency of the first scorer was high for all the game variables. In the heavyweight class, the scoring frequency for the first scorer was high for the attack type and attack area. By contrast, those who did not score first were more frequently found to be in a loss situation. By analyzing the scoring difficulties in different match situations based on whether the competitor scored first, the athletes who scored first in attack type most easily scored first. In losing situations, the athletes who scored first in attack area scored most easily, whereas those who did not score first scored most easily in body and match situations. For the heavyweight class, those who scored first in terms of attack type, counter-attack, and attack area scored the most easily while winning in body and match situations.