• Korean Journal of Radiology
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• v.22 no.4
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• pp.502-512
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• 2021

Objective: To objectively and subjectively assess and compare the characteristics of monoenergetic images [MEI (+)] and polyenergetic images (PEI) acquired by dual-energy CT (DECT) of patients with breast cancer. Materials and Methods: This retrospective study evaluated the images and data of 42 patients with breast cancer who had undergone dual-phase contrast-enhanced DECT from June to September 2019. One standard PEI, five MEI (+) in 10-kiloelectron volt (keV) intervals (range, 40-80 keV), iodine density (ID) maps, iodine overlay images, and Z effective (Z_eff) maps were reconstructed. The contrast-to-noise ratio (CNR) and the signal-to-noise ratio (SNR) were calculated. Multiple quantitative parameters of the malignant breast lesions were compared between the arterial and the venous phase images. Two readers independently assessed lesion conspicuity and performed a morphology analysis. Results: Low keV MEI (+) at 40-50 keV showed increased CNR and SNR_{breast lesion} compared with PEI, especially in the venous phase ([CNR: 40 keV, 20.10; 50 keV, 14.45; vs. PEI, 7.27; p < 0.001], [SNR_{breast lesion}: 40 keV, 21.01; 50 keV, 16.28; vs. PEI, 10.77; p < 0.001]). Multiple quantitative DECT parameters of malignant breast lesions were higher in the venous phase images than in the arterial phase images (p < 0.001). MEI (+) at 40 keV, ID, and Z_eff reconstructions yielded the highest Likert scores for lesion conspicuity. The conspicuity of the mass margin and the visual enhancement were significantly better in 40-keV MEI (+) than in the PEI (p = 0.022, p = 0.033, respectively). Conclusion: Compared with PEI, MEI (+) reconstructions at low keV in the venous phase acquired by DECT improved the objective and subjective assessment of lesion conspicuity in patients with malignant breast lesions. MEI (+) reconstruction acquired by DECT may be helpful for the preoperative evaluation of breast cancer.

• Korean Journal of Radiology
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• v.22 no.2
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• pp.168-178
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• 2021

Objective: To provide an automatic method for segmentation and diameter measurement of type B aortic dissection (TBAD). Materials and Methods: Aortic computed tomography angiographic images from 139 patients with TBAD were consecutively collected. We implemented a deep learning method based on a three-dimensional (3D) deep convolutional neural (CNN) network, which realizes automatic segmentation and measurement of the entire aorta (EA), true lumen (TL), and false lumen (FL). The accuracy, stability, and measurement time were compared between deep learning and manual methods. The intra- and inter-observer reproducibility of the manual method was also evaluated. Results: The mean dice coefficient scores were 0.958, 0.961, and 0.932 for EA, TL, and FL, respectively. There was a linear relationship between the reference standard and measurement by the manual and deep learning method (r = 0.964 and 0.991, respectively). The average measurement error of the deep learning method was less than that of the manual method (EA, 1.64% vs. 4.13%; TL, 2.46% vs. 11.67%; FL, 2.50% vs. 8.02%). Bland-Altman plots revealed that the deviations of the diameters between the deep learning method and the reference standard were -0.042 mm (-3.412 to 3.330 mm), -0.376 mm (-3.328 to 2.577 mm), and 0.026 mm (-3.040 to 3.092 mm) for EA, TL, and FL, respectively. For the manual method, the corresponding deviations were -0.166 mm (-1.419 to 1.086 mm), -0.050 mm (-0.970 to 1.070 mm), and -0.085 mm (-1.010 to 0.084 mm). Intra- and inter-observer differences were found in measurements with the manual method, but not with the deep learning method. The measurement time with the deep learning method was markedly shorter than with the manual method (21.7 ± 1.1 vs. 82.5 ± 16.1 minutes, p < 0.001). Conclusion: The performance of efficient segmentation and diameter measurement of TBADs based on the 3D deep CNN was both accurate and stable. This method is promising for evaluating aortic morphology automatically and alleviating the workload of radiologists in the near future.

• Korean Journal of Radiology
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• v.22 no.3
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• pp.384-394
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• 2021

Objective: To quantitatively assess biochemical alterations in the cartilage of the subtalar and midtarsal joints in chronic lateral ankle instability (CLAI) patients with isolated anterior talofibular ligament (ATFL) injuries and combined calcaneofibular ligament (CFL) injuries using MRI T2 mapping. Materials and Methods: This study was performed according to regulations of the Committee for Human Research at our institution, and written informed consent was obtained from all participants. Forty CLAI patients (26 with isolated ATFL injuries and 14 with combined ATFL and CFL injuries) and 25 healthy subjects were recruited for this study. All participants underwent MRI scans with T2 mapping. Patients were assessed with the American Orthopedic Foot and Ankle Society (AOFAS) rating system. The subtalar and midtarsal joints were segmented into 14 cartilage subregions. The T2 value of each subregion was measured from T2 mapping images. Data were analyzed with ANOVA, the Student's t test, and Pearson's correlation coefficient. Results: T2 values of most subregions of the subtalar joint and the calcaneal facet of the calcaneocuboid joint in CLAI patients with combined CFL injuries were higher than those in healthy controls (all p < 0.05). However, there were no significant differences in T2 values in subtalar and midtarsal joints between patients with isolated ATFL injuries and healthy controls (all p > 0.05). Moreover, T2 values of the medial talar subregions of the posterior subtalar joint in patients with combined CFL injuries showed negative correlations with the AOFAS scores (r = -0.687, p = 0.007; r = -0.609, p = 0.021, respectively). Conclusion: CLAI with combined CFL injuries can lead to cartilage degeneration in subtalar and calcaneocuboid joints, while an isolated ATFL injury might not have a significant impact on the cartilage in these joints.

• Journal of The Korean Association For Science Education
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• v.26 no.4
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• pp.559-567
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• 2006

The purposes of this study were to investigate and compare the perception of students, their parents, and their teachers about students' scientific talent and interest, and to analyze if there is a difference among the perceptions of the three groups by students' gender. For the research, 592 Korean elementary and middle school students, their parents (N=592), and their teachers were sampled and investigated their perceptions, with the questionnaire for students, parents, and teachers developed by the authors and validated by science education experts group. The research results are; (1) in total, the perception scores of parents and teachers are higher than that of students' perception, and the average score of each group decreases by grade in every group; (2) among the students and parents groups, average perception score of male students' talents and interest was higher than that of female students, while teachers perceive averagely that there is no difference in students talents and interest by gender.

• Journal of The Korean Association For Science Education
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• v.26 no.6
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• pp.765-774
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• 2006

The purpose of this study was to suggest an instructional direction for improving scientific problem-finding ability. For this purpose, the present study made an in-depth analysis about activity on problem finding tasks of high school students in an ill-structured scientific problem situation. Subjects were divided into two groups (cooperative and individual) and two kinds of problem finding tasks were administered to two groups. Results indicated that a cooperative activity on problem finding happened to a series of steps exploring problem situation, expressing knowledge and experience, discussing provisional problems, creating various problems and selecting the best problem. Besides, a cooperative activity on problem finding depended heavily on prior knowledge and experience, and in the meantime, various scientific concepts turned out to naturally be expressed. As for the problems found out during a cooperative activity, their scores in creativity factors, including the degree of agreement in original problem selection came out to be on the whole, as excellent. In addition, the types of the problems found out in open problem situation showed that they were more various than those found out in closed problem situation. Subjects perceived that activity on problem finding had positive influence on scientific concept and science process skills. Findings of this study have the following educational implications: First, it is needed to prepare for educational environment that enables students to explore various knowledge and information. Second, the offering of various opportunities is needed to enlarge the scope of scientific knowledge and experience. Third, it is needed to prepare for a study atmosphere that lets students express their knowledge and experiences freely.

• Journal of The Korean Association For Science Education
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• v.26 no.1
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• pp.99-113
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• 2006

In this study, Korean middle school student science achievement results in the "Trends in International Mathematics and Science Study" (TIMSS 2003) were analyzed according to international benchmarks, content area, gender and student attitudes toward science. Overall Korea ranked the third internationally and had a mean score of 558. Korean students achieved top ranking in physics, but fell to the ninth place in chemistry. Unliked their counter parts in similar countries such as Singapore and Chinese Taipei, Korean students did not reach the highest benchmark. Compared to previous assessment, Korean girls showed improved performance; however, significant gender differences still exist in Korea; apparent from the better performance of boys than girls in the study. It is also noteworthy that Korean students were found to have the lowest self-confidence in learning science, a lower valuing science, and less enjoying learning science even though they produced high achievement scores.

• Journal of The Korean Association For Science Education
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• v.29 no.6
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• pp.593-610
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• 2009

The purpose of this study was to investigate students' views on the value of school science lessons and the aspects of science lessons that appeal to students. For the investigation, semi-structured in-depth interviews with 16 secondary school students were conducted. The results showed that about half of the participants thought that science lessons are important, but not all students have to learn science. And they considered only intrinsic interest and career hopes as critical elements in judging the necessity of science education for all. To appeal to students: first, science lessons should have relevance to students' career hopes, interest, curiosity, abilities, real life, experiences, and test scores. Second, they should acquire students' understanding. Third, they should include more experiments. Finally, they should be related to real life, reflect students' interest and concerns, and link new things with what students already know in terms of contexts and contents. Students thought that science lessons are not suitable for students who don't desire to pursue a science-related career. This suggests that present science curriculum perceived by students doesn't match well with the idea of science education for all. To overcome this problem, students need to be included in the debate about the relevance of science curriculum.

• Journal of The Korean Association For Science Education
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• v.29 no.2
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• pp.156-167
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• 2009

This study investigated the effects of dynamic visual on students' field independence-dependence on connecting errors and conceptual understanding in learning chemistry concepts with multiple representations. Seventh graders (N=123) at a co-ed middle school were assigned to a static visual (SV) group learning with text and static visual, and a dynamic visual (DV) group learning with text and dynamic visual. The students then learned 'Boyle's Law' and 'Charles's Law' for two class periods. Results revealed that the percentages of the DV group were lower than those of the SV group on connecting errors. However, the percentages of the students' connecting errors were still high regardless of their field independence-dependence. There was a little different tendency in the percentages of connecting errors between the two groups by students' field independence-dependence according to the types of connecting errors. The scores of the DV group were significantly higher than those of the SV group in a test on conceptual understanding. However, there was no significant interaction between the instruction and the students' field independence-dependence. Educational implications of these findings are discussed.

• Korean Journal of Environment and Ecology
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• v.37 no.6
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• pp.450-463
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• 2023

The objective of this study is to derive the core habitat of the Kirengeshoma koreana Nakai utilizing Habitat Suitability Index (HSI) and Maximum Entropy (MaxEnt) models. Expert-based models have been criticized for their subjective criteria, while statistical models face difficulties in on-site validation and integration of expert opinions. To address these limitations, both models were employed, and their outcomes were overlaid to derive the core habitat. Five variables were identified through a comprehensive literature review and spatial analysis based on appearance coordinates. The environmental variables encompass vegetation zone, forest type, crown density, annual precipitation, and effective soil depth. Through surveys involving six experts, importance rankings and SI (Suitability Index) scores were established for each variable, subsequently facilitating the creation of an HSI map. Using the same variables, the MaxEnt model was also executed, resulting in a corresponding map, which was merged to construct the definitive core habitat map. Out of 16 observed locations of K. koreana, 15 were situated within the identified core habitat. Furthermore, an area historically known to host K. koreana but not verified in the present, Mt. Yeongchwi, was found to lack a core habitat. These findings suggest that the developed models exhibit a high degree of accuracy and effectively reflect the current ecological landscape.

• The Korean Journal of Food And Nutrition
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• v.37 no.1
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• pp.1-8
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• 2024

This study investigated the effect of Lactiplantibacillus plantarum JSA22-fermented rice drinks on dextran sodium sulfate (DSS)-induced colitis in mice. Twenty-four mice were randomly assigned; No colitis (Con), colitis with tap water (DSS-only), colitis with unfermented rice (DSS-UFR), and colitis with fermented rice (DSS-FR). After inducing colitis with 2% DSS for 5 days, they were given Tap water, UFR drink, or FR drink for an additional 6 days. The DSS-FR group had significantly lower Disease Activity Index (DAI) scores compared to the DSS-only group, but no significant difference with the DSS-UFR group. Colon length was reduced in the DSS-only group. The DSS-only group had significantly higher IL-6 mRNA levels compared to the Con group, while the DSS-FR groups showed significantly lower IL-6 mRNA levels compared to the DSS-only group. These results suggest that rice drinks fermented with Lactiplantibacillus Plantarum JSA22 ameliorate the severity of DSS-colitis, by potentially reducing proinflammatory cytokines.