• Journal of Embryo Transfer
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• v.24 no.2
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• pp.109-113
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• 2009

Serial ultrasonography was performed to measure the normal appearance of uterine during estrous cycle and to determine whether the unterine appearance was related to the sex hormone, progesterone and estrogen. The uterine appearances, shape, diameter and echogenicity were daily monitored with ultrasonography in 9 Miniature Schnauzer dogs undergoing II estrous cycles. During proestrus and estrous, the uterus became hypoechoic but developed hyperechoic luminal echo. In the longitudinal view, the shape of the uterus occasionally changed from rectangular to coiled or serpentine, compared to other stages of the cycle. The diameter of the uterus during proestrus and estrous was larger (range: 0.60${\sim}$0.86 mm) than other stages (range: 0.48${\sim}$0.62 mm) of the cycle. The rising estrogen concentrations (range: 14.51${\sim}$16.86 pg/ml) in plasma during proestrus correlated with changes in the uterus (p<0.05). Progesterone concentrations were 0.08${\sim}$0.15 ng/ml at the onset of proestrus, but rose 1.06${\sim}$1.26 ng/ml at the end of proestrus. There was no relation to progesterone concentration from onset of estrus (p>0.05). There was dramatical changes in normal uterus and sex hormone during estrous cycle. Especially, the appearance, shape and diameter of uterus were related to plasma estrogen concentration during proestrus, correlated with other stages of the cycle.

• Journal of Veterinary Clinics
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• v.25 no.5
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• pp.424-428
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• 2008

A 10-year-old castrated male Schnauzer (case 1) and a 13-year-old intact male Schnauzer (case 2) was referred with mass of left hind limb. We performed hemogram, serum chemistry, radiography, ultrasonography, computed tomography, fine needle aspiration and histopathology. The complete blood counts and serum biochemistry results were within the reference range. Radiography showed cutaneous mass with soft tissue density. The lesions of two dogs were revealed a definite marginated hyperechoic mass with vascularization in ultrasonography. Computed tomography showed an isodense mass in the left hind limb region with minimal contrast enhancing in case 1 and heterogenous enhancement in case 2. Cytology from ultrasonographic guided aspiration of the mass was suspected fibrous tissue-derived benign cell in two dogs. A surgical excision was performed in two dogs. In histological examination of the resected mass, cutaneous fibroma was revealed. The two patients were successfully treated by surgery and postoperative care. This report decribes and compares radiographic, ultrasonographic, computed tomographic, cytologic and histopathologic features of the cutaneous fibroma of two schnauzer dogs.

• Journal of Veterinary Clinics
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• v.25 no.6
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• pp.501-505
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• 2008

Serial ultrasonographic examinations were performed on 9 Miniature Schnauzer bitches from day 15 of gestation until parturition to determine the ultrasonographic measurement of gestational structures. Ovulation was designated the day that plasma progesterone concentration exceeded 4.0 ng/ml (day 0). Extra-fetal structures were measured from day 17 or 18 to 60. Outer uterine diameter (OUD) increased from $6.50{\pm}1.06mm$ ($Mean{\pm}SD$) to $50.89{\pm}5.62mm$, inner chorionic cavity diameter (ICCD) increased from $2.10{\pm}0.15mm$ to $37.15{\pm}4.36mm$, and length of placenta (PL) increased from $7.50 {\pm}1.41mm$ to $40.62{\pm}3.27mm$. OUD and ICCD were significantly and linearly relative to gestational age especially through day 37, whereas PL was not significantly relative to gestational age. Of the extra-fetal structures, ICCD was the most accurate for estimation of gestational age before day 38 of gestation. Fetal structures increased at a linear rate to parturition. Fetal crown-rump length (CRL) increased from $2.55{\pm}0.07mm$ on day 22 to $85.25{\pm}9.89mm$ on day 48. Fetal head diameter (HD) increased from $3.43{\pm}0.64mm$ on day 27 to $25.06{\pm}0.41mm$ on day 63. Fetal body diameter (BD) increased from $ 5.96{\pm}0.84mm$ on day 30 to $43.76{\pm}3.36mm$ on day 63. Of the fetal structures, HD was the most accurate for estimation of gestational age after day 38 to parturition.

• Journal of Embryo Transfer
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• v.24 no.3
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• pp.151-157
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• 2009

Serial ultrasonography was conducted on Miniature Schnauzer bitches, on purpose to observe the ultrasonographic appearance of normal ovaries and ovarian structures during the estrous cycle. The size of ovaries was increased from $76.8{\pm}7.5mm^2(Mean{\pm}S.D)$ on Day-12 (Day-0=ovulation day) to $114.4{\pm}5.5mm^2$ on Day-8 and there was no significantly different between both ovaries. The ovaries were recognized by its proximity to the caudal renal pole and appeared moderately echogenic oval shape with a smooth contour. The size of follicles was increased from $8.1{\pm}4.5mm^2$ on Day-12 to $114.4{\pm}5.5mm^2$ on Day-0 and there was no significantly different between both ovaries. The number of follicles was increased from $2.8{\pm}0.7$ on Day-12 to $1.1{\pm}0.1$ on Day-0 and there was no significantly different between both ovaries. The follicles were small anechoic fluid-filled structures in early of proestrus, more increased, and indistinguished from each follicles in late of proestrus. The size of corpora lutea was increased from $19.3{\pm}2.1mm^2$ on Day-0 to $26.4{\pm}8.1mm^2$ on Day-8 and there was no significantly different between both ovaries. The number of corpora lutea was increased from $1.4{\pm}0.6$ on Day-0 to $2.9{\pm}0.4$ on Day-38 and there was no significantly different between both ovaries. The corpora lutea were small anechoic cavity and thin hyperechoic wall in early of diestrus, became more hyperechoic, and increased homogenous structures. The results of this study would be useful for differential diagnosis between normal and abnormal structures of ovaries.

• Journal of Embryo Transfer
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• v.25 no.1
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• pp.77-84
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• 2010

This study was carried out the normal serial ultrasonographic appearance of the postpartum uterine involution with small pet bitches. Postpartum changes in uterine shape, architecture, echogenicity and diameter were monitored with ultrasonography in small pet bitches (Miniature Schnauzer, Cocker Spaniel and Shih-tzu). In the Miniature Schnauzer bitches, uterine diameter of the placental sites and interplacental sites were decreased from $24.31{\pm}1.65\;mm$ at 1 day to $13.56{\pm}0.76\;mm$at 7 day, and $15.19{\pm}1.28\;mm$ at 1 day to $10.41{\pm}0.76\;mm$ at 7 day postpartum. In the Cocker Spaniel, the placental sites and interplacental sites were decreased from $24.90{\pm}1.62\;mm$ at 1 day to $14.14{\pm}1.21\;mm$at 7 day, and $15.33{\pm}1.47\;mm$ at 1 day to $10.19{\pm}0.83\;mm$ at 7 day postpartum. In the Shih-tzu, the placental sites and interplacental sites were decreased from $23.96{\pm}1.55\;mm$at 1 day to $13.84{\pm}0.94\;mm$ at 7 day, and $14.93{\pm}1.29\;mm$ at 1 day to $9.98{\pm}0.84\;mm$ at 7 day postpartum. And uterine diameter was no statistically significant difference among bitches (p>0.05). At 67 days, the uterine diameter in Miniature Schnauzer bitches were 6~7 mm both placental and interplacental sites, and the uterine horns showed uniform hypoechoic, tubular structures without enlargement. In present study, the involution of the uterus was completed at 67 days after parturition in Miniature Schnauzer, and 65 days in Cocker Spaniel and the Shih-tzu. There were no significant differences of normal postpartum uterine involution between small pet bitches (p>0.05). In conclusion, the postpartum involution of small pet bitches appeared to be completed normally at 65~67 days after parturition and could be identified by gross findings such as vaginal discharges and ultrasonographic findings of uterine shape and echogenicity.

• Journal of Veterinary Clinics
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• v.25 no.2
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• pp.79-84
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• 2008

For estimating the ovulation time in Miniature Schnauzer dogs during the estrous cycle, radioimmunoassay of plasma estradiol-$17{\beta}$ and progesterone concentrations was conducted on blood samples in 21 pregnant and 13 non pregnant dogs. When Day 0 was that plasma progesterone concentrations exceeded 4.0 ng/ml, on Day 64, parturition day, progesterone declined below 1.0 ng/ml with $0.92\;{\pm}\;0.29\;ng/ml$ and when Day 0 was that plasma progesterone concentrations declined below 1.0 ng/ml, on Day -64, progesterone increased above 4.0 ng/ml with $4.56\;{\pm}\;0.87\;ng/ml$. Gestational length was $63.71\;{\pm}\;1.35$ (Mean${\pm}$S.D.) days from plasma progesterone concentrations exceeded 4.0 ng/ml and was $66.29\;{\pm}\;1.98$ days from first male acceptance. The plasma estradiol-$17{\beta}$ concentrations reached maximum value with $28.20\;{\pm}\;2.86\;pg/ml$ on Day .2, and plasma progesterone concentrations reached $5.90\;{\pm}\;0.36 ng/ml, 5.18\;{\pm}\;0.32 ng/ml on Day 0, and the maximum of 61.58\;{\pm}\;10.47 ng/ml on Day 19 and 56.05\;{\pm}\;8.86\;ng/ml$ on Day 16 in pregnant and non pregnant dogs, respectively. Afterward, plasma progesterone concentrations declined below 1.0 ng/ml on Day 64 with $0.92\;{\pm}\;0.29\;ng/ml$ in pregnant cycles and on Day 58 with $0.95\;{\pm}\;0.63\;ng/ml$ in non pregnant dogs. No difference were found pregnant and non pregnant dogs in plasma estradiol-$17{\beta}$ and progesterone concentrations (p<0.01). Based on first male acceptance (Day 0), the maximum of plasma estradiol-$17{\beta}$ concentrations ($29.31\;{\pm}\;3.61\;pg/ml$) occurred on Day -1 and plasma progesterone concentrations exceeded 4.0 ng/ml on Day 2 in pregnant ($5.37\;{\pm}\;0.76\;ng/ml$) and non pregnant ($4.25\;{\pm}\;0.80\;ng/ml$) dogs. These results suggest that in Miniature Schnauzers, the ovulation occurred when plasma progesterone concentrations exceeded 4.0 ng/ml, 3 days after plasma estradiol-$17{\beta}$ peak and 2 days after first male acceptance.

• Journal of Embryo Transfer
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• v.23 no.1
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• pp.13-18
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• 2008

Vaginal cytology with behavioral observation was performed in 34 estrous cycles in 16 Miniature Schnauzer dogs to evaluate the its usefulness. The mean duration of proestrus and estrus in Miniature Schnauzer based on behavioral observation and vaginal cytology was $7.58{\pm}1.50$ (Mean ${\pm}$S.D., range: $5{\sim}10$) and $8.46{\pm}2.82\;(6{\sim}17)$ days for proestrus, and $6.97{\pm}1.66\;(4{\sim}10)$ and $10.29{\pm}2.61\;(6{\sim}19)$ days for estrus, respectively. The duration of each phase of the estrous cycle was not significantly different based on between behavioral observation and vaginal cytology. The gestational length from the first day of male acceptance was $66.55{\pm}2.91\;(64{\sim}76)$ days, $57.70{\pm}1.92\;(54{\sim}62)$ days from the first male refusal, and $56.90{\pm}1.62\;(54{\sim}60)$ days from the onset of cytologic diestrus, respectively. Vaginal cytology during the estrous cycle were significantly characteristic of large intermediate cells in proestrus, anuclear cells in estrus, small intermediate cells in diestrus, and parabasal cells and small intermediate cells in anestrus (p<0.001), respectively. Cornification index (CI) by vaginal cytology was higher in proestrus ($69.90{\pm}1.44%$) and estrus ($91.35{\pm}1.09%$), then it was decreased in diestrus ($13.53{\pm}1.28%$) and anestrus ($1.16{\pm}1.26%$).

• Journal of Animal Science and Technology
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• v.53 no.5
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• pp.429-434
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• 2011

The objectives of this research were to determine the effects of brown rice (BR) on food intake, digestion, energy value, and fecal characteristics. Three replacement levels which BR replaced 0, 15 and 30% of wheat flour were tested. Six female Miniature Schnauzer (8~9 month age, initial mean body weight 5.0 ${\pm}$ 0.3 kg) were assigned to treatments in replicated $3{\times}3$ Latin square design. Total tract digestibilities of DM, OM, acid hydrolyzed fat and gross energy except CP increased linearly (P<0.01), and observed digestible energy and metabolizable energy values also increased linearly (P=0.001 and P=0.006, respectively) with increasing BR replacement level. Wet and dry fecal output decreased linearly (P<0.001, P=0.004) with increasing BR inclusion to the diets and BR 30% treatment reduced wet fecal output up to 21% of that of control. Quadratic (P<0.01) effects was observed in fecal score for dog fed BR and fecal ammonia concentration tended to increase linearly (P=0.07) in response to increasing BR replacement level. It seems that the increase in fecal ammonia concentration may be partially related to the decrease in shortchain fatty acid concentration (P=0.001). This study clearly demonstrates that BR improves nutrients digestibility and fecal characteristics of dog.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2006.05a
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• pp.185-185
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• 2006

• Journal of Veterinary Clinics
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• v.33 no.1
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• pp.43-47
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• 2016

A 7-year-old castrated male Schnauzer was presented with melena and inappetence. Laboratory examination revealed mild anemia. Abdominal ultrasonography showed abnormal enlargement of intestinal segment and a oval mass with soft tissue density. After surgical resection of the enlarged intestine including the mass, histopathologic examination showed that the mass was tentatively diagnosed as synchronous occurrence of gland cell- and mesenchymal cell-origin tumors. Subsequently, immunohistochemistry showed positivity to cytokeratin AE1/AE3 in the gland cells and positivity to ${\alpha}-smooth$ muscle-specific actin, but negative expression of c-Kit, suggesting the co-existence of adenocarcinoma and leiomyosarcoma. Follow-up examination after 3-year of the surgery confirmed that the dog remained healthy and did not show recurrence of the tumors.