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Warthin's Tumor of the Parotid Gland (이하선의 Warthin씨 종양)

  • Lee Kang-Young;Chung Woong-Youn;Park Cheong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.12 no.2
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    • pp.177-180
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    • 1996
  • Warthin's tumor is a benign and slow growing tumor found exclusively in the parotid gland or the periparotid lymph nodes. It mostly affects males between the age of forty to seventy years and is closely related with smoking history. Between January 1981 and June 1996, 42 patients underwent surgical excision of Warthin's tumor of the parotid gland; which made up 10.6% of all parotid gland surgeries(398 cases) during the same period. Their ages ranged from 36 to 75 years with a mean age of 56 years. There were 33 male and 9 female patients with a 4.3 : 1 male to female ratio. The majority of the tumors were situated in the parotid tail whereas one was in the deep lobe. Bilateral simultaneous involvements of the parotid gland were found in 4 patients(9.5%) ; therefore total of 46 parotid glands were involved. Four(8.7%) of the 46 parotid glands had multifocal tumors ranginging from two to three lumps. Tumor sizes varied from 1.5 to 6.0cm with mean diameter of 3.lcm. Of the 42 patients, 26(61.9%) were diagnosed preoperatively or peroperatively by means of CT scans, ultrasound, 99m-Tc. scan, fine needle aspiration cytology or intraoperative frozen section biopsy. Of the 46 tumors, 30 underwent a superficial(n=29) or total(n=1) parotidectomy and for 16 cases with tumors suspected preoperatively or peroperatively of being single Warthin's tumor, only enucleation was performed. No cases of recurrence were identified during the follow up period regardless of type of operation performed, however the postoperative complication rate was much higher in the parotidectomy group(33.3%) than in the enucleation only group(12.5%). We feel that an enucleation procedure may be appropriate for the patients with single Warthin's tumor.

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Temporospatial clustering analysis of foot-and-mouth disease transmission in South Korea, 2010~2011 (시공간 클러스터링 분석을 이용한 2010~2011 국내 발생 구제역 전파양상)

  • Bae, Sun-Hak;Shin, Yeun-Kyung;Kim, Byunghan;Pak, Son-Il
    • Korean Journal of Veterinary Research
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    • v.53 no.1
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    • pp.49-54
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    • 2013
  • To investigate the transmission pattern of geographical area and temporal trends of the 2010~2011 foot-and-mouth disease (FMD) outbreaks in Korea, and to explore temporal intervals at which spatial clustering of FMD cases space-time analysis based on georeferenced database of 3,575 burial sites, from 30 November 2010 to 23 February 2011, was performed. The cases represent approximately 98.1% of all infected farms (n = 3,644) during the same period. Descriptive maps of spatial patterns of the outbreaks were generated by ArcGIS. Spatial Scan Statistics, using SaTScan software, was applied to investigate geographical clusters of FMD cases across the country. Overall, spatial heterogeneity was identified, and the transmission pattern was different by province. Cattle have more clusters in number but smaller in size, as compared to the swine population. In addition, spatiotemporal analysis and the comparison of clustering patterns between the first 7 days and days 8 to 14 of the outbreak revealed that the strongest spatial clustering was identified at the 7-day interval, although clustering over longer intervals (8~14 days) was also observed. We further discussed the importance of time period elapsed between FMD-suspected notice and the date of confirmation, and emphasized the necessity of region-specific and species-specific control measures.

A 10-year follow-up study on clinical outcomes of dental implant rehabilitation using surgical guide

  • Haoyun Li;Mi Young Eo;Kezia Rachellea Mustakim;Soung Min Kim
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.50 no.2
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    • pp.70-79
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    • 2024
  • Objectives: The surgical guide is a static computer-assisted device used for implant surgery planning and guidance. By taking an impression and referring to the patients' three-dimensional computed tomography scan of the desired implant site, a surgical guide can be created. During surgery, the surgical guide aids in achieving the designed implant placement position and direction. We examined and evaluated the long-term clinical outcomes of implant surgery using surgical guides. Materials and Methods: This study investigated a total of 15 patients with 32 implants that were placed using surgical guides from 2009 to 2011 with a mean follow-up period extended beyond 10 years. Patient demographics and implant survival rates were recorded. We analyzed marginal bone loss (MBL) by assessing the radiographs acquired at installation, three months after installation, and one month, one, two, and five years after prosthesis delivery. Results: The mean patient age was 57.33 years at implant placement. Of the 32 implants, five implants were placed in the anterior region and 27 implants were in the posterior region. Six implants failed and three of them were replaced, resulting in an 81.25% survival rate. The mean follow-up period was 10 years and nine months. Mean MBL compared to post-installation was significantly higher than at three months after installation, and one month, one, two, and five years after prosthesis delivery. Mean MBL at three months after installation, and one month, one year, and two years were significantly higher compared to the previous visit (P<0.05). However, MBL at five years after prosthesis delivery did not differ significantly compared to at two years. Conclusion: In this study, implant rehabilitation assisted by surgical guides exhibited favorable survival rates. With the limitation of the sample amount in this study, further research and more samples are required to evaluate the long-term clinical effectiveness of surgical guides.

USE OF CORTICOSTEROIDS IN THE TREATMENT OF LOCALIZED LANGERHANS CELL HISTIOCYTOSIS OF THE MANDIBLE : CASE REPORT (Corticosteroid를 이용한 하악에 발현된 Langerhans Cell Histiocytosis의 치료 : 증례보고)

  • Choi, Jung-Yong;Lee, Sang-Hwa;Yoon, Hyun-Joong
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.31 no.3
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    • pp.249-253
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    • 2009
  • Langerhans cell histiocytosis(LCH), previously known as histiocytosis X, is rare, proliferative disorder in which the accumulation of pathologic Langerhans cell leads to tissue infiltration and destruction. The jaw is involved 10~20% of all LCH and most common oral symptoms are jaw swelling or a palpation mass. Most of subjects are males and disease appears to start before the age of 10 years. An 11 years old girl was referred from pediatric department. Histological examination confirmed the diagnosis LCH. She was treated intra-lesional injection of corticosteroid. The overall outcome was excellent. After a follow-up period of 20 month, the patient present with no evidence of residual disease on Panoramic view and whole body bone scan. We report this early recognized LCH case treated by corticoid injection in good progress with literature review.

Trace Measurement of Ruthenium by Adsorptive Stripping Voltammetry (벗김 전압전류법에 의한 루테늄의 미량 측정)

  • Czae, Myung Zoon;Kwon, Young Soon;Kim, So Jin
    • Journal of the Korean Chemical Society
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    • v.41 no.5
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    • pp.246-250
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    • 1997
  • In the presence of optimum amounts of hydroxylamine, trace ruthenium(III) can be conveniently determined in acidic (boric) media by coupling catalytic hydrogen processes with adsorptive accumulation of the catalyst, using differential pulse voltammetry. Cyclic voltammetry was used to characterize the redox and interfacial processes. Optimal experimental conditions were found to be a stirred borate (0.015 M, pH 2.5) solution containing 0.55 M hydroxylamine, a preconcentration potential of - 0.70 V, and a scan rate of 5 mV/s. With a 7 min accumulation period the detection limit was 3${\times}$10-10 M. The possible interferences by other platinum group metals are investigated.

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Pulmonary Nodular Lymphoid Hyperplasia in a 33-Year-Old Woman

  • Park, Ji Ye;Park, Seong Yong;Haam, Seokjin;Jung, Joonho;Koh, Young Wha
    • Journal of Chest Surgery
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    • v.51 no.2
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    • pp.133-137
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    • 2018
  • Pulmonary nodular lymphoid hyperplasia is a reactive lymphoproliferative disease. It is very rare, which means that many aspects of the disease are unknown or have not been proven. Pulmonary nodular lymphoid hyperplasia can be symptomatic or asymptomatic, progressive or not, and solitary or multiple, and a surgical approach is the current treatment of choice. We present a case of pulmonary nodular lymphoid hyperplasia that was visualized as multiple ground glass opacities on a computed tomography (C T) scan, and observed for 1 year because the patient was pregnant. Over this period, the number and extent of the opacities progressed, but no symptoms were reported. A surgical biopsy was done and some remaining lesions regressed on follow-up CT scans, while others progressed, without any appearance of symptoms.

Reverse engineering of concentric plug cover by 3D scanning and development of injection mold (3D 스캔을 이용한 콘센트 커버의 역설계 및 금형 개발)

  • Kim, Dong-Wook;Choi, Young-Rock;Shin, Sang-Eun;Kim, Sei-Hwan;Choi, Kyu-Kwang;Han, Seong-Ryeol
    • Design & Manufacturing
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    • v.9 no.1
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    • pp.18-22
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    • 2015
  • Mold making and product manufacturing process was made by a die through a number of stages. Thereby, it takes a long period of time from the manufacture of mold until passed the products to consumers. However, it is not possible to meet the diverse desires purchasing of consumer. We made a 3D CAD Model aligned with product scan data using reverse engineering. Utilizing thereafter flow analysis to derive the optimal mold conditions, by applying the condition, and devised a mold fabrication process that is much shorter than the conventional process for fabricating a mold. In this study, the outlet cover to the product, it describes a process, as a result, it was confirmed that the number of steps can be shortened much more than the conventional process.

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Adsorptive Stripping Voltammetric Determination of Ruthenium (흡착 벗김법에 의한 루테늄 정량)

  • Hong, Tae-Kee;Kwon, Young-Soon;Czae, Myung-Zoon
    • Analytical Science and Technology
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    • v.10 no.2
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    • pp.119-125
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    • 1997
  • A stripping voltammetric procedure for determining ruthenium was developed, based on the adsorptive accumulation of ruthenium in the presence of hydrazine in acidic acetate buffer. After preconcentration of ruthenium compelex and reduction, the ruthenium-catalyzed hydrogen current at -0.84V was measured by differential pulse voltammetry. Optimal experimental conditions were found to be a stirred acetate buffer solution(pH 2.0) containing 0.01M acetate and 0.01M hydrazine, accumulation potential of -0.76V, and a scan rate of 5mV/s. The detection limit was $2{\times}10^{-9}M$ for a 7 min accumulation period. The possible interferences by other platinum group metals were also investigated.

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Open Lung Biopsy for Diffuse Interstitial Lung Disease (미만성 간질성 폐질환의 개흉 폐 생검)

  • Seong, Suk-Hwan;Seo, Pil-Won
    • Journal of Chest Surgery
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    • v.27 no.10
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    • pp.850-853
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    • 1994
  • Open lung biopsy was performed in thirty patients for the diagnosis and staging evaluation of interstitial lung disease during the period from January 1987 until December 1992. The age of the patients ranged from 14 to 71 years [mean 48 years], and the patients consisted of 14 males and 16 females. Preoperative FEV1`s were from 0.80 liter to 3.88 liters [mean 1.66]. Other non-invasive diagnostic studies such as PCNA, bronchoalveolar lavage, TBLB, and gallium scan were also done in addition to X-ray and high-resolution chest CT. Tweaty-eight were correctly diagnosed and 2 cases were not [diagnostic yield rate 93.3%]. Among the 28 cases,pathologic diagnosis influenced further treatment regimens and prognostic expectations in 23 cases [82.1%]. The diagnostic non-invasive studies other than open lung biopsy yielded a correct diagnosis without staging only in 5 cases. There was no mortality and only one complication, ARDS ; however, the patient recovered after 5 days ventilator support. Open lung biopsy, which is the gold standard for the diagnosis and staging evaluation of interstitial lung disease can be done safely and has value in clinical decision making. Also knowledge of the involvement of the lesion is important for proper selection of the biopsy site.

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Detection of Recurrence in a Surveillance Program for Epithelial Ovarian Cancer

  • Suprasert, Prapaporn;Chalapati, Wadwilai
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7193-7196
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    • 2013
  • Ovarian cancer patients need a surveillance program for the detection of tumor progression after completion of treatment. The methods generally consist of history taking, physical examination, tumor marker monitoring and imaging. However, the details of recurrence detection with each method are not well defined. To clarify this issue, ovarian cancer patients who achieved complete or partial responses and developed tumor progression at the follow up time between January 2004 and December 2010 in University Hospital Chiang Mai, Thailand, were reviewed. Clinical data, CA 125 level and imaging results at the tumor progression time were recorded and analyzed. There were 144 ovarian cancer patients meeting the inclusion criteria with the mean age of 51 years and 62.5% of them were in an advanced stage. Complete response was achieved in 89 patients (61.8%) after primary treatment. The median progression free survival and overall survival were 15.5 months and 37.5 months, respectively. Abnormal symptoms presented in 49.3% of the studied patients and 59.7% developed physical examination abnormalities. In addition, CA 125 was elevated in 89.6% while in 74.3% of tumor progression was identified by CT-scan. Short treatment time period and a high level of CA 125 were significant independent prognostic factors in these patients. In conclusion, careful history taking, physical examination and monitoring of CA 125 levels are important methods for tumor progression detection in a surveillance program for epithelial ovarian cancer patients.