• Animal Systematics, Evolution and Diversity
• /
• v.16 no.2
• /
• pp.177-182
• /
• 2000

Sponges of the genus Sarcotragus are very poorly known in the world. Two new species of Sarcotragus, S. maraensis n. sp. and S. gapaensis n. sp., are described from Korea.

• Journal of Species Research
• /
• v.5 no.3
• /
• pp.443-458
• /
• 2016

Ten new species of genus Sarcotragus (Demospongiae: Dictyoceratida: Irciniidae) are described from Geomundo Island and Jejudo Island, Korea. All new species of the Sarcotragus are distinguished from the other reported species of Sarcotragus by the skeletal structure, especially fasciculate primary fibres. The characters of genus Sarcotragus have cylindrical primary fascicles filled with wads of filaments or flattened fascicles. All of the primary fibres are not cored with foreign debris. Secondary fibres have slightly fasciculate branch or plastic-like web. They are all not cored with foreign debris. All skeletal fibres are very irregular. The surface is covered with loose or tight filamentous membrane.

• Journal of Species Research
• /
• v.6 no.spc
• /
• pp.135-147
• /
• 2017

Seven new species in two genera, Sarcotragus and Bergquistia (Demospongiae: Dictyoceratida: Irciniidae), are described from Jeju Island, Korea. The separation of the two genera was made on basis of morphological evidence in skeletal structure, especially fasciculation of primary fibres and filament thickness. Two new species in the genus Sarcotragus and five new species in the genus Bergquistia are compared with other reported species.

• Natural Product Sciences
• /
• v.11 no.1
• /
• pp.50-53
• /
• 2005

Bioassay-directed fractionation of the lipophilic extract of a marine sponge Sarcotragus sp. led to the isolation of a known trisoxazole containing macrolide, mycalolide B (1). Its structure was identified by NMR and MS analyses. This is the first report on the isolation of macrolide from a sponge of the genus Sarcotragus (Order: Dictyoceratida).

• Bulletin of the Korean Chemical Society
• /
• v.23 no.10
• /
• pp.1467-1469
• /
• 2002

• Natural Product Sciences
• /
• v.21 no.4
• /
• pp.237-239
• /
• 2015

Sarcotragin C (1), a new sesterterpene metabolite was isolated from a Sarcotragus sp. sponge collected from Chuja Island, Korea. On the basis of the combined spectroscopic analyses, the structure of this compound was determined to be a linear norsesterterpene containing a leucine-derived ${\gamma}-lactam$ moiety. This compound exhibited moderate cytotoxicity against K562 and A549 cell-lines.

• Journal of the Korean Magnetic Resonance Society
• /
• v.12 no.1
• /
• pp.33-39
• /
• 2008

Four sesterterpenoids were isolated from AMPK activity-guided fraction of marine sponge Sarcotragus species. Their planar structures were determined from combination of extensive 1D and 2D NMR experiments and MS data, and the configuration at the chiral centers were assigned by comparison with the $^1H$ and $^{13}C$ chemical shifts of the known compounds. Among four compounds, compound 2 was found to be a new sarcotrine derivative. Though not strong, compounds 1-4 moderately showed AMPK activation effect on L6 myoblast cell through Western Blot analysis.

• 한국생물공학회:학술대회논문집
• /
• 2003.04a
• /
• pp.15-17
• /
• 2003

• Proceedings of the PSK Conference
• /
• 2002.10a
• /
• pp.256.1-256.1
• /
• 2002

We investigated the anti-proliferative effects of a new compound. ircinin-1. from the sponge Sarcotragus sp. on SK-MEL -2 human skin cancer cells. From the data of MTT assay, cell viability was decreased by ircinin-1 in a dose-dependent manner. We observed that the anti-proliferative effect of ircinin-1 was due to the induction of apoptosis, which was confirmed by observing the morphological changes. the increased ratio of pro-apoptotic protein Bax to anti-apoptotic protein Bcl-2, and cleavage of poly(ADP-ribose) polymerase protein, via activation of caspase-3. (omitted)

• Proceedings of the Zoological Society Korea Conference
• /
• 2002.04a
• /
• pp.70.2-70
• /
• 2002

No Abstract, See Full Text