• Journal of the Korean Magnetics Society
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• v.17 no.4
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• pp.156-161
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• 2007

To develop array magnetic sensors, specular-type giant magnetoresistive- spin valve (GMR-SV) film of Glass/Ta(5)MiFe(7)/IrMn(10)NiFe(5)/$O_2$/CoFe(5)/Cu(2.6)/CoFe(5)/$O_2$/NiFe(7)/Ta(5)(nm) was deposited by using a high-vacuum sputtering system. One of 15 way sensors in the area of $8{\times}8mm^2$ was Patterned a size of $20{\times}80{\mu}m^2$ in multilayer sample by Photo-lithography. All of 15 sensors with Cu electrodes were measured a uniform magnetic properties by 2-probe method. The highest magnetic sensitivity of MR and output voltage measured nearby an external magnetic field of 5 Oe were MS = 0.5%/Oe and ${\triangle}$V= 3.0 mV, respectively. An easy-axis of top-free layers of $CoFe/O_2/NiFe$ with shape anisotropy was perpendicular to one of bottom-pinned layers $IrMn/NiFe/O_2/CoFe$. When the sensing current increased from 1 mA to 10 mA, the output working voltage uniformly increased and the magnetic sensitivity was almost stable to use the nano-magnetic devices with good sensitive properties.

• Analytical Science and Technology
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• v.20 no.5
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• pp.424-433
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• 2007

An analytical method for the determination of thyroid hormones in plasma samples has been studied by solid-phase extraction and high-performance liquid chromatography/diode array detector (DAD)/electrospray ionization (ESI)-mass spectrometer. Seven thyroid hormones were successfully separated by gradient elution on the reverse phase Hypersil ODS column (4.6 mm I.D., 250 mm length, particle size $5{\mu}m$) with ammonium formate buffer and acetonitrile. In addition, these compounds were confirmed by UV spectra and ESI-mass Spectra. The extraction recoveries of thyroid hormones in the plasma sample (at pH 3) were in the range of 74.5-115.7 % with solid-phase extraction by C18, followed by elution with 4 mL of methanol. The calibration curves showed good linearity with the correlation coefficients ($r^2$) varying from 0.9939 to 0.9978 and the detection limits of all analytes were obtained in the range of 20-50 ng/mL (38.1-162.8 pmol/mL). As a result, thyroxine was found in the range of 50.98-112.97 ng/mL in normal plasma samples.

• The Research Journal of the Costume Culture
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• v.9 no.4
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• pp.616-628
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• 2001

The purpose of this research is to create a polyester sample book that serves as a point of reference that exporters in the Taegu area can allude to when exporting to the U.S. By getting this project off the ground, we can expect to make a worthy contribution to the manufacture of high-quality, value-added fashion & textile goods. The research was conducted as follows. First, a study was carried out in the local market ensued by consumer surveys with regards to consumer attitude on man-made fibers, market researches, and interviews with experts, all in conjunction with the Color Association of the U.S. Also, a diverse array of fabric swatches were collected from Manhattans fabric wholesalers and then classified by color and fabric type fur the sample book. In short, this research found that man-made fibers have full marketability in the U.S. Thus, in order for Taegus synthetic textile firms to be successful in exporting to the US, it is essential that they come up with fabrics that have properties resembling natural fibers such as having a soft hand, natural sheen, smooth draping, and diverse textures as well as being in line with the current trends. In addition, it is also necessary to develop fabrications that are versatile and functional. Thus, by developing innovative fabrications, the synthetic textile business will turn toward the production of high-quality synthetics and will also provide a platfrom for strengthening the competitive edge of Koreas textile & fashion business.

• Bioinformatics and Biosystems
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• v.1 no.1
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• pp.67-72
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• 2006

The aim of this paper is to discuss the effect of missing values in detecting differentially expressed genes in a cDNA microarray experiment in the context of a one sample problem. We conducted a cDNA micro array experiment to detect differentially expressed genes for the metastasis of colorectal cancer based on twenty patients who underwent liver resection due to liver metastasis from colorectal cancer. Total RNAs from metastatic liver tumor and adjacent normal liver tissue from a single patient were labeled with cy5 and cy3, respectively, and competitively hybridized to a cDNA microarray with 7775 human genes. We used $M=log_2(R/G)$ for the signal evaluation, where Rand G denoted the fluorescent intensities of Cy5 and Cy3 dyes, respectively. The statistical problem comprises a one sample test of testing E(M)=0 for each gene and involves multiple tests. The twenty cDNA microarray data would comprise a matrix of dimension 7775 by 20, if there were no missing values. However, missing values occur for various reasons. For each gene, the no missing proportion (NMP) was defined to be the proportion of non-missing values out of twenty. In detecting differentially expressed (DE) genes, we used the genes whose NMP is greater than or equal to 0.4 and then sequentially increased NMP by 0.1 for investigating its effect on the detection of DE genes. For each fixed NMP, we imputed the missing values with K-nearest neighbor method (K=10) and applied the nonparametric t-test of Dudoit et al. (2002), SAM by Tusher et al. (2001) and empirical Bayes procedure by $L\ddot{o}nnstedt$ and Speed (2002) to find out the effect of missing values in the final outcome. These three procedures yielded substantially agreeable result in detecting DE genes. Of these three procedures we used SAM for exploring the acceptable NMP level. The result showed that the optimum no missing proportion (NMP) found in this data set turned out to be 80%. It is more desirable to find the optimum level of NMP for each data set by applying the method described in this note, when the plot of (NMP, Number of overlapping genes) shows a turning point.

• Korean Journal of Pharmacognosy
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• v.40 no.4
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• pp.298-302
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• 2009

Samultang is one of traditional medicine composed of Paeonia lactiflora, Angelica gigas, Rehmannia glutinosa and Cnidium officinale. To develop simultaneous determination of paeoniflorin, decursin and 5-HMF in Samultang, a high performance liquid chromatography with diode array detector was used. To separate three marker components, Dionex $C_{18}$ column (5 ${\mu}m$, 120 ${\AA}$, 4.6 mm${\times}$150 mm) was used with a gradient elution system of water and methanol. UV wavelength of detector set at 230 nm and 280 nm. This method was validated by linearity, precision test and recovery test. Calibration curves of three standard components were showed good linear regression ($R^2$>0.9973). LOD and LOQ ranged from 0.08 ${\mu}g$/ml to 0.38 ${\mu}g$/ml and 0.25 ${\mu}g$/ml to 1.16 ${\mu}g$/ml, respectively. The relative standard deviations (RSDs) of data of the inter-day and intra-day experiments were less than 0.54% and 0.89%, respectively. The measured results of recovery test were varied from 93.36 to 107.79 with RSD values 0.01~1.45%. The established method was applied for separation of bio-conversion Samultang sample and compared with control sample.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.48 no.4
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• pp.153-159
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• 2011

The MUSIC (MUltiple SIgnal Classification) method estimates the directions of arrival (DOAs) of the signals impinging on a sensor array based on the fact that the noise subspace is orthogonal to the signal subspace. In the conventional MUSIC, an estimate of the basis for the noise subspace is obtained by eigendecomposing the sample matrix, which is computationally expensive. In this paper, we present a simple DOA estimation method which finds an estimate of the signal subspace basis directly from the columns of the sample matrix from which the noise power components are removed. DOA estimates are obtained by searching for minimum points of a cost function which is defined using the estimated signal subspace basis. The minimum points are efficiently found through the Brent method which employs parabolic interpolation. Simulation shows that the simple estimation method virtually has the same performance as the complex conventional method based on the eigendecomposition.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.40 no.1
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• pp.15-23
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• 2003

This paper proposes a fast direction of arrival (DOA) estimation algorithm that can rapidly estimate incidence angles of incoming signals using a pseudo covariance matrix. The conventional subspace DOA estimation methods such as MUSIC (multiple signal classification) algorithms need many sample signals to acquire covariance matrix of input signals. Thus, it is difficult to estimate the DOAs of signals because they cannot perform DOA estimation during receiving sample signals. Also if the D0As of signals are changing rapidly, conventional algorithms cannot estimate incidence angles of signals exactly. The proposed algorithm obtains bearing response and directional spectrum after acquiring pseudo covariance matrix of each snapshot. The incidence angles can be exactly estimated by using the bearing response and directional spectrum. The proposed DOA estimation algorithm uses only concurrent snapshot so as to obtain covariance matrix. Compared to conventional DOA estimation methods. The proposed algorithm has an advantage that can estimate DOA of signal rapidly.

• Journal of Korea Water Resources Association
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• v.51 no.5
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• pp.383-393
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• 2018

The regional frequency analysis is the method which uses not only sample of target station but also sample of neighborhood stations in which are classified as hydrological homogeneous regions. Consequently, identification of homogeneous regions is a very important process in regional frequency analysis. In this study, homogeneous regions for regional frequency analysis of precipitation were identified by the self-organizing map (SOM) which is one of the artificial neural network. Geographical information and hourly rainfall data set were used in order to perform the SOM. Quantization error and topographic error were computed for identifying the optimal SOM map. As a result, the SOM model organized by $7{\times}6$ array with 42 nodes was selected and the selected stations were classified into 6 clusters for rainfall regional frequency analysis. According to results of the heterogeneity measure, all 6 clusters were identified as homogeneous regions and showed more homogeneous regions compared with the result of previous study.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.495-497
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• 2015

Galaxies can be "pre-processed" in the low-density outskirts by ambient medium in the filaments or tidal interactions with other galaxies while falling into the cluster. In order to probe how early on and by which mechanisms galaxies can be affected before they enter high-density cluster environments, we are carrying out an atomic hydrogen ($H\small{I}$) imaging study of a sample of galaxies selected from three filamentary structures around the Virgo cluster. Our sample consists of 14 late-type galaxies, which are potentially interacting with their surroundings. The $H\small{I}$ observations have been done using the Westerbork Synthesis Radio Telescope, the Giant Metrewave Radio Telescope, and the Jansky Very Large Array with column density sensitivity of ${\approx}3-5{\times}10^{19}cm^{-2}$ in $3{\sigma}$ per channel, which is low enough to detect faint $H\small{I}$ features in the outer disks of galaxies. In this work, we present the Hi data of two galaxies that were observed with GMRT. We examine the $H\small{I}$ morphology and kinematics to find the evidence for gas-gas and/or tidal interactions, and discuss which mechanism(s) could be responsible for pre-processing in these cases.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.08a
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• pp.275-275
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• 2013

Osteoblast is one of cells related with osseointegration and many research have conducted the adhesion of osteoblast onto the surface of implant. In the osseointegration, biocompatibility of the implant and cell adhesion to the surface are important factors. The researches related to cell adhesion have a direction from micro-scaled surface roughness to nano-scaled surface roughness with advancing nanotechnology. A cell reacts and sense to stimuli from extracellular matrix (ECM) and topography of the ECM [1]. Thus, for better osseointegration, we should provide an environment similar to ECM. In this study, we synthesize TiO2 nanowires using hydrothermal reaction because TiO2 provides inertness to titanium on its surface and enables it used as an implant material for the orthopedic treatment such as fixation of the bone fracture [2]. Ti substrate is immersed into NaOH aqueous solution. The solution are heated at $140{\sim}200^{\circ}C$ for various time (10~720 minutes). After heat treatment, we take out the sample and immerse it into HCl aqueous solution for 1 hour. The acid treated sample is heated again at $500^{\circ}C$ for 3 hours [3]. Then, we culture osteoblast on the TiO2 nanowires. For investigating cell adhesion onto nanostructured surface, we conduct several tests such as MTT assay, ALP (Alkaline phosphatase) activity assay, measuring calcium expression, and so on. These preliminary results of the cell culture on the nanowires are foundation for investigating cell-material interaction especially with nanostructure interaction.